Questioning the depolarizing effects of GABA during early brain development.

abstract：:Gamma-aminobutyric acid type A (GABAA) receptors expressed within the medial preoptic area (mPOA) are known to play a critical role in regulating sexual and neuroendocrine functions. In the rat brain, high levels of expression of the gamma1 subunit mRNA of the GABAA receptor are restricted to a limited number of regio...

journal_title：Journal of neurophysiology

authors： Nett ST,Jorge-Rivera JC,Myers M,Clark AS,Henderson LP

更新日期：1999-01-01 00:00:00

abstract：:Previous behavioral work has shown the existence of both anticipatory and reactive grip force responses to predictable load perturbations, but how the brain implements anticipatory control remains unclear. Here we recorded electroencephalographs while participants were subjected to predictable and unpredictable extern...

journal_title：Journal of neurophysiology

authors： Kourtis D,Kwok HF,Roach N,Wing AM,Praamstra P

更新日期：2008-02-01 00:00:00

abstract：:The primate posterior thalamus has been proposed to contribute to pain sensation, but its precise role is unclear. This is in part because spinothalamic tract (STT) neurons that project to the posterior thalamus have received little attention. In this study, antidromic mapping was used to identify individual STT neuro...

journal_title：Journal of neurophysiology

authors： Davidson S,Zhang X,Khasabov SG,Simone DA,Giesler GJ Jr

更新日期：2008-10-01 00:00:00

abstract：:Reports of cholecystokinin (CCK) binding and expression of CCK receptors in neonatal rodent spinal cord suggest that CCK may influence neuronal excitability. In patch-clamp recordings from 19/21 ventral horn motoneurons in neonatal (PN 5-12 days) rat spinal cord slices, we noted a slowly rising and prolonged membrane ...

journal_title：Journal of neurophysiology

authors： Oz M,Yang KH,Shippenberg TS,Renaud LP,O'Donovan MJ

更新日期：2007-09-01 00:00:00

abstract：:Rewards in the natural environment are rarely predicted with complete certainty. Uncertainty relating to future rewards has typically been defined as the variance of the potential outcomes. However, the asymmetry of predicted reward distributions, known as skewness, constitutes a distinct but neuroscientifically under...

journal_title：Journal of neurophysiology

authors： Burke CJ,Tobler PN

更新日期：2011-11-01 00:00:00

abstract：:Intrathecally applied nicotine reduces bradykinin-induced plasma extravasation (BK-induced PE) in the rat knee joint. This depression is mediated by the hypothalamo-pituitary-adrenal (HPA) axis and is enhanced by interruption of impulse traffic in afferents of the abdominal vagus nerve. Like intrathecal nicotine, elec...

journal_title：Journal of neurophysiology

authors： Miao FJ,Jänig W,Green PG,Levine JD

更新日期：1997-09-01 00:00:00

abstract：:Spontaneous and stimulus-evoked excitatory postsynaptic currents (EPSCs) were recorded in calyx nerve terminals from the turtle vestibular lagena to quantify key attributes of quantal transmission at this synapse. On average, EPSC events had a magnitude of ∼ 42 pA, a rise time constant of τ(0) ∼ 229 μs, decayed to bas...

journal_title：Journal of neurophysiology

authors： Highstein SM,Mann MA,Holstein GR,Rabbitt RD

更新日期：2015-06-01 00:00:00

abstract：:Thalamic intralaminar and medial nuclei participate mainly in affective and motivational aspects of pain processing. Unique to the present study were identification and characterization of spontaneously active neurons in the central lateral nucleus (CL) of the intralaminar thalamus, which were found to respond only to...

journal_title：Journal of neurophysiology

authors： Ren Y,Zhang L,Lu Y,Yang H,Westlund KN

更新日期：2009-07-01 00:00:00

abstract：:The continuous perception of motion-through-depth is critical for both navigation and interacting with objects in a dynamic three-dimensional (3D) world. Here we used 3D tracking to simultaneously assess the perception of motion in all directions, facilitating comparisons of responses to motion-through-depth to fronto...

journal_title：Journal of neurophysiology

authors： Bonnen K,Huk AC,Cormack LK

更新日期：2017-09-01 00:00:00

abstract：:The role of the nitric oxide (NO)-cGMP signaling cascade in modulation of peripheral nociception is controversial. Although behavioral studies have suggested both pro- and anti-nociceptive effects, little is known about the direct action of this signaling cascade on primary afferent nociceptive neurons that mediate th...

journal_title：Journal of neurophysiology

authors： Levy D,Strassman AM

更新日期：2004-08-01 00:00:00

abstract：:Some neurons in early visual cortex are highly selective for the position of oriented edges in their receptive fields (simple cells), whereas others are largely position insensitive (complex cells). These characteristics are reflected in their sensitivity to the spatial phase of moving sine-wave gratings: simple cell ...

journal_title：Journal of neurophysiology

authors： Cloherty SL,Ibbotson MR

更新日期：2015-01-15 00:00:00

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00

abstract：:The octopus cells of the posteroventral cochlear nucleus receive inputs from auditory-nerve fibers and form one of the major ascending auditory pathways. They respond to acoustic and electrical stimulation transiently and are believed to carry temporal information in the precise timing of their action potentials. The ...

journal_title：Journal of neurophysiology

authors： Cai Y,Walsh EJ,McGee J

更新日期：1997-08-01 00:00:00

abstract：:Properties of calcium spikes revealed during GABAA receptor antagonism in hippocampal CA1 neurons from guinea pigs. J. Neurophysiol. 78: 2269-2279, 1997. Intracellular electrical responses and changes in intracellular calcium concentration ([Ca2+]i) in response to activation of synaptic inputs and to DC injections wer...

journal_title：Journal of neurophysiology

authors： Miura M,Yoshioka M,Miyakawa H,Kato H,Ito KI

更新日期：1997-11-01 00:00:00

abstract：:We have used a slice preparation of the infant rat midbrain to examine converging inputs onto neurons in the deeper multisensory layers of the superior colliculus (dSC). Electrical stimulation of the superficial visual layers (sSC) and of the auditory nucleus of the brachium of the inferior colliculus (nBIC) evoked ro...

journal_title：Journal of neurophysiology

authors： Skaliora I,Doubell TP,Holmes NP,Nodal FR,King AJ

更新日期：2004-11-01 00:00:00

abstract：:The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

journal_title：Journal of neurophysiology

authors： Dahlem K,Valko Y,Schmahmann JD,Lewis RF

更新日期：2016-05-01 00:00:00

abstract：:Intracellular recordings were made from rhythm-generating interneurons in the Lymnaea feeding system. The feeding pattern is a three-phase rhythm of interneuronal activity (N1, N2, N3) corresponding to protraction, rasp, and swallow. We describe the firing pattern and anatomy of the premotor interneurons, each of whic...

journal_title：Journal of neurophysiology

authors： Elliott CJ,Benjamin PR

更新日期：1985-12-01 00:00:00

abstract：:Visual tracking of moving targets requires the combination of smooth pursuit eye movements with catch-up saccades. In primates, catch-up saccades usually take place only during pursuit initiation because pursuit gain is close to unity. This contrasts with the lower and more variable gain of smooth pursuit in cats, whe...

journal_title：Journal of neurophysiology

authors： de Brouwer S,Missal M,Lefèvre P

更新日期：2001-08-01 00:00:00

abstract：:Whereas Kvbeta2 subunits modulate potassium current properties carried by Kv1 channel complexes in heterologous systems, little is known about the contributions of Kvbeta2 subunits to native potassium channel function. Using antisense approaches and in situ recordings from Xenopus embryo spinal cord neurons, we tested...

journal_title：Journal of neurophysiology

authors： Pineda RH,Knoeckel CS,Taylor AD,Estrada-Bernal A,Ribera AB

更新日期：2008-10-01 00:00:00

abstract：:The human motor system regulates arm mechanics to produce stable postures during interactions with different physical environments. This occurs partly via involuntary mechanisms, including stretch reflexes. Previous single-joint studies demonstrated enhanced reflex sensitivity during interactions with compliant enviro...

journal_title：Journal of neurophysiology

authors： Perreault EJ,Chen K,Trumbower RD,Lewis G

更新日期：2008-05-01 00:00:00

abstract：:1. Retzius (R) neurons of the fifth and sixth segmental ganglia of the leech, called R(5,6) neurons are specialized to innervate the adjacent reproductive organs and are morphologically and functionally distinct from R neurons of standard ganglia [R(x) cells]. In this study the electrical properties of the R(x) and R(...

journal_title：Journal of neurophysiology

authors： Merz DC

更新日期：1995-03-01 00:00:00

abstract：:P/Q-type voltage-dependent Ca(2+) channels (VDCCs) are highly expressed in the cerebellum, and mutations of these channels are associated with disrupted motor function. Several allelic variants of the alpha1A pore-forming subunit of P/Q-type VDCCs have been described, and mice homozygous for these mutations exhibit ga...

journal_title：Journal of neurophysiology

authors： Katoh A,Jindal JA,Raymond JL

更新日期：2007-02-01 00:00:00

abstract：:Single-channel recording techniques were used to characterize mechanosensitive channels in identified (1.1'-dioctadecyl-3,3,3', 3'-tetramethylindocarbocyanine methanesulfonate labeled) colon sensory neurons dissociated from adult S1 dorsal root ganglia. Channels were found in 30% (7/23) of patches in a cell-attached c...

journal_title：Journal of neurophysiology

authors： Su X,Wachtel RE,Gebhart GF

更新日期：2000-08-01 00:00:00

abstract：:Recent studies have pointed to olfactory system beta oscillations of the local field potential (15-30 Hz) and their roles both in learning and as specific responses to predator odors. To describe odorant physical properties, resultant behavioral responses and changes in the central olfactory system that may induce the...

journal_title：Journal of neurophysiology

authors： Lowry CA,Kay LM

更新日期：2007-07-01 00:00:00

abstract：:Perceptual decision making is often modeled as perfect integration of sequential sensory samples until the accumulated total reaches a fixed decision bound. In that view, the buildup of neural activity during perceptual decision making is attributed to temporal integration. However, an alternative explanation is that ...

journal_title：Journal of neurophysiology

authors： Carland MA,Marcos E,Thura D,Cisek P

更新日期：2016-02-01 00:00:00

abstract：:Recent discoveries of visceral nociceptive inputs sharing the classical tactile pathway in the dorsal-column medial lemniscus system have opened a new venue for the investigation of somatovisceral interactions. The current study was designed to determine whether somatic innocuous inputs modulate visceral nociceptive t...

journal_title：Journal of neurophysiology

authors： Zhang HQ,Al-Chaer ED,Willis WD

更新日期：2002-09-01 00:00:00

abstract：:Neurons in monkey orbitofrontal cortex (OF) are known to respond to reward-predicting cues with a strength that depends on the value of the predicted reward as determined 1) by intrinsic attributes including size and quality and 2) by extrinsic factors including the monkey's state of satiation and awareness of what ot...

journal_title：Journal of neurophysiology

authors： Roesch MR,Olson CR

更新日期：2005-10-01 00:00:00

abstract：:Considerable evidence suggests that brain stem pedunculopontine tegmentum (PPT) cholinergic cells are critically involved in the normal regulation of wakefulness and rapid eye movement (REM) sleep. However, much of this evidence comes from indirect studies. Thus, although involvement of PPT cholinergic neurons has bee...

journal_title：Journal of neurophysiology

authors： Datta S,Siwek DF

更新日期：1997-06-01 00:00:00

abstract：:Families of peptide neuromodulators are believed to play important roles in neural networks that control behaviors. Here, we investigate the expression and role of one such group of modulators, the myomodulins, in the feeding system of Lymnaea stagnalis. Using a combination of in situ hybridization and antibody staini...

journal_title：Journal of neurophysiology

authors： Perry SJ,Straub VA,Kemenes G,Santama N,Worster BM,Burke JF,Benjamin PR

更新日期：1998-05-01 00:00:00

abstract：:We report a novel phenomenon produced by focused ultrasound (US) that may be important for understanding its effects on cell membranes. When a US burst (2.1 MHz, 1-mm focal diameter, 0.1-1 MPa) was focused on a motor axon of the crayfish neuromuscular junction, it consistently produced a fast hyperpolarization, which ...

journal_title：Journal of neurophysiology

authors： Lin JW,Yu F,Müller WS,Ehnholm G,Okada Y

更新日期：2019-02-01 00:00:00