Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade.

abstract：:The concept of hierarchical motor control has been viewed as a means of progressively decreasing the number of variables manipulated by each higher control level. We tested the hypothesis that turning an individual bimanual force-production task into a joint (two-participant) force-production task would lead to positi...

journal_title：Journal of neurophysiology

authors： Masumoto J,Inui N

更新日期：2015-06-01 00:00:00

abstract：:Persistent inward currents are important to motoneuron excitability and firing behaviors and also have been implicated in excitotoxicity. In particular, L-type Ca2+ channels, usually located on motoneuron dendrites, play a primary role in amplification of synaptic inputs. However, recent experimental findings on L-typ...

journal_title：Journal of neurophysiology

authors： Mousa MH,Elbasiouny SM

更新日期：2020-10-01 00:00:00

abstract：:Neocortical circuits exhibit a rich dynamic repertoire, and their ability to achieve entrainment (adjustment of their frequency to match the input frequency) is thought to support many cognitive functions and indicate functional flexibility. Although previous studies have explored the influence of various circuit prop...

journal_title：Journal of neurophysiology

authors： Papasavvas CA,Trevelyan AJ,Kaiser M,Wang Y

更新日期：2020-03-01 00:00:00

abstract：:The tactile sensations mediated by the whisker-trigeminal system allow rodents to efficiently detect and discriminate objects. These capabilities rely strongly on the temporal and spatial structure of whisker deflections. Subthreshold but also spiking receptive fields in the barrel cortex encompass a large number of v...

journal_title：Journal of neurophysiology

authors： Le Cam J,Estebanez L,Jacob V,Shulz DE

更新日期：2011-08-01 00:00:00

abstract：:Flexible behavior requires the ability to delay a response until it is appropriate. This can be achieved by holding either a sensory or a motor representation online. Here we assess whether maintenance of sensory or motor material drives the motor system to different functional states, as indexed by alterations of cor...

journal_title：Journal of neurophysiology

authors： van den Hurk P,Mars RB,van Elswijk G,Hegeman J,Pasman JW,Bloem BR,Toni I

更新日期：2007-02-01 00:00:00

abstract：:In the present study, we sought to unravel how exploratory movements affect length perception of rods that are held in and wielded by hand. We manipulated the mechanical rod properties--mass (m), first moment of mass distribution (M), major principal moment of inertia (I(1))--individually, allowing us to assess the re...

journal_title：Journal of neurophysiology

authors： Debats NB,van de Langenberg RW,Kingma I,Smeets JB,Beek PJ

更新日期：2010-11-01 00:00:00

abstract：:Cold-sensitive and nociceptive neural pathways interact to shape the quality and intensity of thermal and pain perception. Yet the central processing of cold thermosensation in the human brain has not been extensively studied. Here, we used magnetoencephalography and EEG in healthy volunteers to investigate the time c...

journal_title：Journal of neurophysiology

authors： Fardo F,Vinding MC,Allen M,Jensen TS,Finnerup NB

更新日期：2017-05-01 00:00:00

abstract：:The timing of brief stationary sounds has been shown to alter the perceived speed of visual apparent motion (AM), presumably by altering the perceived timing of the individual frames of the AM stimuli and/or the duration of the interstimulus intervals (ISIs) between those frames. To investigate the neural correlates o...

journal_title：Journal of neurophysiology

authors： Kafaligonul H,Albright TD,Stoner GR

更新日期：2018-09-01 00:00:00

abstract：:The two-dimensional distribution of population activity in the superior colliculus (SC) during saccadic eye movements in the monkey was estimated using radial basis functions. To make these ensemble activity estimates, cells in the deeper layers of the SC were recorded over much of the rostrocaudal (caudal to 3.8 mm f...

journal_title：Journal of neurophysiology

authors： Anderson RW,Keller EL,Gandhi NJ,Das S

更新日期：1998-08-01 00:00:00

abstract：:Synaptic dynamics comprise a variety of interacting processes acting on a wide range of time scales. This enables a synapse to perform a large array of computations, from temporal and spatial filtering to associative learning. In this study, we describe how changing synaptic gain via long-term plasticity can act to sh...

journal_title：Journal of neurophysiology

authors： Lewis JE,Maler L

更新日期：2004-02-01 00:00:00

abstract：:Interhemispheric interactions through the corpus callosum play an important role in the control of bimanual forces. However, the extent to which physiological connections between primary motor cortices are modulated during increasing levels of bimanual force generation in intact humans remains poorly understood. Here ...

journal_title：Journal of neurophysiology

authors： Long J,Tazoe T,Soteropoulos DS,Perez MA

更新日期：2016-03-01 00:00:00

abstract：:The rate and the total amount of Ca2+ elevation in the presynaptic terminals of bullfrog sympathetic ganglia depend on the firing frequency of the terminals. Carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial uncoupler, was used for testing whether mitochondrial Ca2+ uptake is one of the mechanisms that ...

journal_title：Journal of neurophysiology

authors： Peng YY

更新日期：1998-07-01 00:00:00

abstract：:The role of GAT-3 transporters in regulating GABA(A) receptor-mediated inhibition was examined in the rat neocortex using an in vitro slice preparation. Pharmacologically isolated GABA(A) receptor-mediated responses were recorded from layer V neocortical pyramidal cells, and the effects of SNAP-5114, a GAT-3 GABA tran...

journal_title：Journal of neurophysiology

authors： Kinney GA

更新日期：2005-12-01 00:00:00

abstract：:The basal ganglia participate in motor functions and are implicated in the pathophysiology of movement disorders. It has been shown in primates that the activity of many neurons in one of the basal ganglia output nuclei, the internal segment of the globus pallidus, changes with active or passive movements. The involve...

journal_title：Journal of neurophysiology

authors： Wichmann T,Kliem MA

更新日期：2004-02-01 00:00:00

abstract：:Recent evidence implicates the superior colliculus (SC) in cognitive processes, such as target selection and control of spatial attention, in addition to the execution of saccadic eye movements. We report here the presence of a cognitive response in some cells in the SC in a task that requires the long-term associatio...

journal_title：Journal of neurophysiology

authors： Lee KM,Keller EL

更新日期：2006-06-01 00:00:00

abstract：:The neuronal mechanism which gives rise to the synchronization of motor-unit discharges has been inferred from an analysis of the interspike intervals of individual motor-unit discharges recorded from the soleus muscle. The motor units were divided into two groups on the basis of characteristic changes in their spike ...

journal_title：Journal of neurophysiology

authors： Mori S

更新日期：1975-07-01 00:00:00

abstract：:Damage to the cerebellum causes characteristic movement abnormalities but is thought to have minimal impact on somatosensory perception. Traditional clinical assessments of patients with cerebellar lesions reveal no perceptual deficits despite the fact that the cerebellum receives substantial somatosensory information...

journal_title：Journal of neurophysiology

authors： Bhanpuri NH,Okamura AM,Bastian AJ

更新日期：2012-03-01 00:00:00

abstract：:In layer 2/3 of neocortex, brief trains of action potentials in pyramidal neurons (PNs) induce the mobilization of endogenous cannabinoids (eCBs), resulting in a depression of GABA release from the terminals of inhibitory interneurons (INs). This depolarization-induced suppression of inhibition (DSI) is mediated by ac...

journal_title：Journal of neurophysiology

authors： Lemtiri-Chlieh F,Levine ES

更新日期：2007-11-01 00:00:00

abstract：:Human functional magnetic resonance imaging (fMRI) studies, as well as lesion, drug, and single-cell recording studies in animals, suggest that the striatum plays a key role in associating sensory events with rewarding actions, both by facilitating reward processing and prediction (i.e., reinforcement learning) and by...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Seger CA

更新日期：2013-10-01 00:00:00

abstract：:The relation between impedance change and the location and magnitude of a tonic synaptic conductance was examined in compartmental motoneuron models based on previously published data. The dependency of motoneuron impedance on system time constant (tau), electrotonic length (L), and dendritic-to-somatic conductance ra...

journal_title：Journal of neurophysiology

authors： Maltenfort MG,Phillips CA,McCurdy ML,Hamm TM

更新日期：2004-09-01 00:00:00

abstract：:Several studies have demonstrated that motor adaptations to a novel task environment can be transferred between limbs. Such interlimb transfer of motor commands is consistent with the notion of centrally driven strategies that can be generalized across different frames of reference. So far, studies of interlimb transf...

journal_title：Journal of neurophysiology

authors： Houldin A,Chua R,Carpenter MG,Lam T

更新日期：2012-08-01 00:00:00

abstract：:Visual input provides vital information for helping us modify our walking pattern. For example, artificial optic flow can drive changes in step length during locomotion and may also be useful for augmenting locomotor training for individuals with gait asymmetries. Here we asked whether optic flow could modify the acqu...

journal_title：Journal of neurophysiology

authors： Finley JM,Statton MA,Bastian AJ

更新日期：2014-03-01 00:00:00

abstract：:In the rodent whisker system, a key model for neural processing and behavioral choices during active sensing, whisker motion is increasingly recognized as only part of a broader motor repertoire employed by rodents during active touch. In particular, recent studies suggest whisker and head motions are tightly coordina...

journal_title：Journal of neurophysiology

authors： Schroeder JB,Ritt JT

更新日期：2016-04-01 00:00:00

abstract：:The rapid detection of sensory inputs is crucial for survival. Sensory detection explicitly requires the integration of incoming sensory information and the ability to distinguish between relevant information and ongoing neural activity. In this study, head-fixed rats were trained to detect the presence of a brief def...

journal_title：Journal of neurophysiology

authors： Ollerenshaw DR,Bari BA,Millard DC,Orr LE,Wang Q,Stanley GB

更新日期：2012-07-01 00:00:00

abstract：:Senosory neurons manifest pronounced changes in excitability during maturation, but the factors contributing to this ubiquitous developmental phenomenon are not well understood. To assess the contribution of intrinsic membrane properties to such changes in excitability, in the present study whole cell patch-clamp reco...

journal_title：Journal of neurophysiology

authors： Wang GY,Ratto G,Bisti S,Chalupa LM

更新日期：1997-12-01 00:00:00

abstract：:The tail and paws in rodents are heat exchangers involved in the maintenance of core body temperature (T(core)). They are also the most widely used target organs to study acute or chronic "models" of pain. We describe the fluctuations of vasomotor tone in the tail and paws in conditions of thermal neutrality and the c...

journal_title：Journal of neurophysiology

authors： El Bitar N,Pollin B,Karroum E,Pincedé I,Mouraux A,Le Bars D

更新日期：2014-11-01 00:00:00

abstract：:Support-surface movements are commonly used to examine balance control. Subjects typically receive a series of identical or randomly interspersed multidirectional balance perturbations and the atypical "first trial reaction" (evoked by the first perturbation) is often excluded from further analysis. However, this proc...

journal_title：Journal of neurophysiology

authors： Oude Nijhuis LB,Allum JH,Borm GF,Honegger F,Overeem S,Bloem BR

更新日期：2009-06-01 00:00:00

abstract：:Small lesions designed to completely destroy the cortical zone of representation of a restricted band of frequency were introduced within the primary auditory cortex (AI) in adult cats. Physiological mapping was used to guide placement of lesions. Sound-localization performance was evaluated prior to and after inducti...

journal_title：Journal of neurophysiology

authors： Jenkins WM,Merzenich MM

更新日期：1984-11-01 00:00:00

abstract：:To probe the mechanism of visual suppression, we have raised macaques with strabismus by disinserting the medial rectus muscle in each eye at 1 mo of age. Typically, this operation produces a comitant, alternating exotropia with normal acuity in each eye. Here we describe an unusual occurrence: the development of seve...

journal_title：Journal of neurophysiology

authors： Adams DL,Economides JR,Horton JC

更新日期：2015-05-01 00:00:00

abstract：:For primary auditory cortex (AI) laminae, there is little evidence of functional specificity despite clearly expressed cellular and connectional differences. Natural sounds are dominated by dynamic temporal and spectral modulations and we used these properties to evaluate local functional differences or constancies ac...

journal_title：Journal of neurophysiology

authors： Atencio CA,Schreiner CE

更新日期：2010-01-01 00:00:00