Selective impact of MeCP2 and associated histone deacetylases on the dynamics of evoked excitatory neurotransmission.

abstract：:Response properties of cells in the infragranular layers of cortical area 17 of the cat were examined in the absence of input from supragranular layers. Supragranular activity was silenced either reversibly by cooling the surface of cortex or permanently by making a cryogenic lesion of the supragranular layers. Visual...

journal_title：Journal of neurophysiology

authors： Schwark HD,Malpeli JG,Weyand TG,Lee C

更新日期：1986-10-01 00:00:00

abstract：:Understanding neural responses with natural stimuli has increasingly become an essential part of characterizing neural coding. Neural responses are commonly characterized by a linear-nonlinear (LN) model, in which the output of a linear filter applied to the stimulus is transformed by a static nonlinearity to determin...

journal_title：Journal of neurophysiology

authors： Sharpee TO,Miller KD,Stryker MP

更新日期：2008-05-01 00:00:00

abstract：:An important new study by Kvarta, Bradbrook, Dantrassy, Bailey, and Thompson (J Neurophysiol 114: 1713-1724, 2015) examined the effects of persistent stress and excessive glucocorticoid levels on hippocampal function and emotional behavior in rodents. The authors specifically implicate the temporoammonic pathway as be...

journal_title：Journal of neurophysiology

authors： McGinn MA,Pahng AR

更新日期：2017-02-01 00:00:00

abstract：:Epiretinal implants for the blind are designed to stimulate surviving retinal neurons, thus bypassing the diseased photoreceptor layer. Single-unit or multielectrode recordings from isolated animal retina are commonly used to inform the design of these implants. However, such electrical recordings provide limited info...

journal_title：Journal of neurophysiology

authors： Weitz AC,Behrend MR,Lee NS,Klein RL,Chiodo VA,Hauswirth WW,Humayun MS,Weiland JD,Chow RH

更新日期：2013-04-01 00:00:00

abstract：:The preceding study demonstrated that normal subjects compensate for the additional interaction torques generated when a reaching movement is made during voluntary trunk rotation. The present paper assesses the influence of trunk rotation on finger trajectories and on interjoint coordination and determines whether sim...

journal_title：Journal of neurophysiology

authors： Pigeon P,Bortolami SB,DiZio P,Lackner JR

更新日期：2003-01-01 00:00:00

abstract：:The voltage-gated K(+) channel Kv1.3 has been reported to regulate transmitter release in select central and peripheral neurons. In this study, we evaluated its role at the synapse between visceral sensory afferents and secondary neurons in the nucleus of the solitary tract (NTS). We identified mRNA and protein for Kv...

journal_title：Journal of neurophysiology

authors： Ramirez-Navarro A,Glazebrook PA,Kane-Sutton M,Padro C,Kline DD,Kunze DL

更新日期：2011-06-01 00:00:00

abstract：:Our goal was to understand how patterns of excitation and inhibition, interacting across arrays of ganglion cells in space and time, generate the spiking output pattern for each ganglion cell type. We presented the retina with a 1-s flashed square, 600 microm on a side, and measured patterns of excitation and inhibiti...

journal_title：Journal of neurophysiology

authors： Roska B,Molnar A,Werblin FS

更新日期：2006-06-01 00:00:00

abstract：:The stress hormone corticosterone increases the amplitude of the slow afterhyperpolarization (sAHP) in CA1 pyramidal neurons, without affecting resting membrane potential, input resistance, or action potential characteristics. We here examined how corticosterone affects these properties in the basolateral amygdala (BL...

journal_title：Journal of neurophysiology

authors： Liebmann L,Karst H,Sidiropoulou K,van Gemert N,Meijer OC,Poirazi P,Joëls M

更新日期：2008-02-01 00:00:00

abstract：:We recorded single-unit activity of 25 units in the parafoveal representation of macaque V1 to transient appearance of sinusoidal gratings. Gratings were systematically varied in spatial phase and in one or two of the following: contrast, spatial frequency, and orientation. Individual responses were compared based on ...

journal_title：Journal of neurophysiology

authors： Victor JD,Purpura KP

更新日期：1998-08-01 00:00:00

abstract：:Task-dependent selectivity of movement-related neuronal activity in the primate prefrontal cortex. J. Neurophysiol. 80: 3392-3397, 1998. We studied movement-related neuronal activity in the dorsolateral prefrontal cortex from the perspective of a general role for the prefrontal cortex in controlling motor behavior to ...

journal_title：Journal of neurophysiology

authors： Hoshi E,Shima K,Tanji J

更新日期：1998-12-01 00:00:00

abstract：:Outward K+ currents were recorded using a whole cell patch-clamp configuration, from acutely dissociated adult rat cutaneous afferent dorsal root ganglion (DRG) neurons (L4 and L5) identified by retrograde labeling with Fluoro-gold. Recordings were obtained 16-24 h after dissociation from cells between 39 and 49 mm in...

journal_title：Journal of neurophysiology

authors： Everill B,Rizzo MA,Kocsis JD

更新日期：1998-04-01 00:00:00

abstract：:We have found new evidence for gamma-aminobutyric acid (GABA)-induced intrinsic optical changes associated with a voltage-sensitive dye signal in the early embryonic chick brain stem slice. The slices were prepared from 8-day-old embryos, and they were stained with a voltage-sensitive dye (NK2761). Pressure ejection o...

journal_title：Journal of neurophysiology

authors： Momose-Sato Y,Sato K,Hirota A,Kamino K

更新日期：1998-04-01 00:00:00

abstract：:We hypothesized that epilepsy affects the activity of the autonomic nervous system even in the absence of seizures, which should manifest as differences in heart rate variability (HRV) and cardiac cycle. To test this hypothesis, we investigated ECG traces of 91 children and adolescents with generalized epilepsy and 25...

journal_title：Journal of neurophysiology

authors： Sivakumar SS,Namath AG,Tuxhorn IE,Lewis SJ,Galán RF

更新日期：2016-04-01 00:00:00

abstract：:Synaptic currents are frequently assumed to make a major contribution to the extracellular field potential (EFP). However, in any neuronal population, the explicit separation of synaptic sources from other contributions such as postsynaptic spikes remains a challenge. Here we take advantage of the simple organization ...

journal_title：Journal of neurophysiology

authors： McColgan T,Kuokkanen PT,Carr CE,Kempter R

更新日期：2019-03-01 00:00:00

abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...

journal_title：Journal of neurophysiology

authors： Valeyev AY,Hackman JC,Holohean AM,Wood PM,Katz JL,Davidoff RA

更新日期：1999-07-01 00:00:00

abstract：:Previous studies of spiral ganglion neuron electrophysiology have shown that specific parameters differ according to cochlear location, with apical neurons being distinctly different from basal neurons. To align these features more precisely along the tonotopic axis of the cochlea, we developed a novel spiral ganglion...

journal_title：Journal of neurophysiology

authors： Liu Q,Davis RL

更新日期：2007-10-01 00:00:00

abstract：:The octopus cells of the posteroventral cochlear nucleus receive inputs from auditory-nerve fibers and form one of the major ascending auditory pathways. They respond to acoustic and electrical stimulation transiently and are believed to carry temporal information in the precise timing of their action potentials. The ...

journal_title：Journal of neurophysiology

authors： Cai Y,Walsh EJ,McGee J

更新日期：1997-08-01 00:00:00

abstract：:1. Compartmental models were used to compute the time constants and coefficients of voltage and current transients in hypothetical neurons having tapering dendrites or soma shunt and in a serially reconstructed motoneuron with soma shunt. These time constants and coefficients were used in equivalent cylinder formulas ...

journal_title：Journal of neurophysiology

authors： Holmes WR,Rall W

更新日期：1992-10-01 00:00:00

abstract：:1. The synaptic connections of 44 single identified muscle spindle Ia afferents and of 21 Golgi tendon organ (Ib) afferents from medial gastrocnemius (MG) were studied in 46 cats by the spike-triggered averaging of synaptic noise in 803 motoneurons of various types. 2. The well-known monosynaptic Ia excitatory connect...

journal_title：Journal of neurophysiology

authors： Watt DG,Stauffer EK,Taylor A,Reinking RM,Stuart DG

更新日期：1976-11-01 00:00:00

abstract：:The spider VS-3 slit-sense organ contains two types of primary mechanoreceptor neurons that are morphologically similar but have different electrical behavior. Type A neurons fire only one or two action potentials in response to a mechanical or electrical step of any amplitude above the threshold, whereas type B neuro...

journal_title：Journal of neurophysiology

authors： Torkkeli PH,French AS

更新日期：2002-03-01 00:00:00

abstract：:Retinal Müller cells are highly permeable to potassium as a consequence of their intrinsic membrane properties. Therefore these cells are able to play an important role in maintaining potassium homeostasis in the vertebrate retina during light-induced neuronal activity. Polyamines and other factors present in Müller c...

journal_title：Journal of neurophysiology

authors： Solessio E,Rapp K,Perlman I,Lasater EM

更新日期：2001-04-01 00:00:00

abstract：:Postembryonic developmental changes in electrophysiological properties of the AIY interneuron class were investigated using whole cell voltage clamp. AIY interneurons displayed an increase in cell capacitance during larval development, whereas steady-state current amplitude did not increase. The time course of the out...

journal_title：Journal of neurophysiology

authors： Faumont S,Boulin T,Hobert O,Lockery SR

更新日期：2006-06-01 00:00:00

abstract：:1. The present study was designed to determine the effects of microstimulation of the medullary reticular formation (MRF) on the locomotor activity of the cat in the absence of phasic afferent feedback from the limbs. To this end, both short (33 ms) and long (200 ms) trains of stimuli (trains of 0.2-ms pulses at 330 H...

journal_title：Journal of neurophysiology

authors： Perreault MC,Rossignol S,Drew T

更新日期：1994-01-01 00:00:00

abstract：:1. The discharge of individual neurons in the visual cortex and lateral geniculate nucleus (LGN) of anesthetized and paralyzed cats and kittens was examined for the presence of oscillatory activity. Neural firing was evoked through the monoptic or dichoptic presentation of drifting gratings and random sequences of fla...

journal_title：Journal of neurophysiology

authors： Ghose GM,Freeman RD

更新日期：1992-11-01 00:00:00

abstract：:The exercise pressor reflex, a crucial component of the cardiovascular response under physiological and pathophysiological states, is activated via metabolic and mechanical mediators that originate from contracting muscles and stimulate group III and IV afferents. We reported previously that stimulation of mu opioid r...

journal_title：Journal of neurophysiology

authors： Hassan B,Kim JS,Farrag M,Kaufman MP,Ruiz-Velasco V

更新日期：2014-12-15 00:00:00

abstract：:1. We have stimulated responses of stellate cells in the anteroventral cochlear nucleus (AVCN) to single-formant stimuli (SFSs) with the use of recorded auditory-nerve fiber (ANF) responses as inputs. In particular, two important features of temporal discharge patterns, the phase locking to best frequency (BF) tones a...

journal_title：Journal of neurophysiology

authors： Wang X,Sachs MB

更新日期：1995-04-01 00:00:00

abstract：:The continuous perception of motion-through-depth is critical for both navigation and interacting with objects in a dynamic three-dimensional (3D) world. Here we used 3D tracking to simultaneously assess the perception of motion in all directions, facilitating comparisons of responses to motion-through-depth to fronto...

journal_title：Journal of neurophysiology

authors： Bonnen K,Huk AC,Cormack LK

更新日期：2017-09-01 00:00:00

abstract：:The mechanisms behind the therapeutic effects of electrical stimulation of the brain in epilepsy and other disorders are poorly understood. Previous studies in vitro have shown that uniform electric fields can suppress epileptiform activity through a direct polarizing effect on neuronal membranes. Such an effect depen...

journal_title：Journal of neurophysiology

authors： Mikkelsen R,Andreasen M,Nedergaard S

更新日期：2013-06-01 00:00:00

abstract：:Numerous models of the oculomotor neuronal integrator located in the prepositus hypoglossi nucleus (PHN) involve both highly tuned recurrent networks and intrinsic neuronal properties; however, there is little experimental evidence for the relative role of these two mechanisms. The experiments reported here show that ...

journal_title：Journal of neurophysiology

authors： Idoux E,Serafin M,Fort P,Vidal PP,Beraneck M,Vibert N,Mühlethaler M,Moore LE

更新日期：2006-07-01 00:00:00

abstract：:Hyolaryngeal elevation is essential for airway protection during swallowing and is mainly a reflexive response to oropharyngeal sensory stimulation. Targeted intramuscular electrical stimulation can elevate the resting larynx and, if applied during swallowing, may improve airway protection in dysphagic patients with i...

journal_title：Journal of neurophysiology

authors： Burnett TA,Mann EA,Stoklosa JB,Ludlow CL

更新日期：2005-12-01 00:00:00