Task-dependent selectivity of movement-related neuronal activity in the primate prefrontal cortex.

abstract：:Nervous systems are thought to encode information as patterns of electrical activity distributed sparsely through networks of neurons. These networks then process information by transforming one pattern of electrical activity into another. To store information as a pattern, a neural network must strengthen synapses be...

journal_title：Journal of neurophysiology

authors： Jackson MB

更新日期：2013-12-01 00:00:00

abstract：:1. Single-unit recordings were made, under moderate gaseous anesthesia (33% O2-66% N2O + 0.5/0.6% halothane), in the ventrobasal (VB) thalamic complex of rats (n = 42) with a mononeuropathy created 2-3 wk beforehand, by four loose ligatures around the common sciatic nerve. Before the recording session, three behaviora...

journal_title：Journal of neurophysiology

authors： Guilbaud G,Benoist JM,Jazat F,Gautron M

更新日期：1990-11-01 00:00:00

abstract：:1. Using the patch-clamp technique, we investigated whether the glutamate-elicited current in mechanically isolated cone photoreceptors from the salamander retina is generated by a Cl- channel or a glutamate transporter. 2. The current reversed near the equilibrium potential for Cl-, was decreased by three Cl- channel...

journal_title：Journal of neurophysiology

authors： Picaud SA,Larsson HP,Grant GB,Lecar H,Werblin FS

更新日期：1995-10-01 00:00:00

abstract：:Single-unit recordings were obtained from 107 horizontal semicircular canal-related central vestibular neurons in three alert squirrel monkeys during passive sinusoidal whole-body rotation (WBR) while the head was free to move in the yaw plane (2.3 Hz, 20 degrees /s). Most of the units were identified as secondary ves...

journal_title：Journal of neurophysiology

authors： Gdowski GT,McCrea RA

更新日期：1999-07-01 00:00:00

abstract：:A prominent characteristic of neurons in the whisker system is their selectivity to the direction in which a whisker is deflected. The aim of this study was to determine how information about whisker direction is encoded at successive levels of the lemniscal pathway. We made extracellular recordings under identical co...

journal_title：Journal of neurophysiology

authors： Bale MR,Petersen RS

更新日期：2009-11-01 00:00:00

abstract：:Behavioral, ethological, and electrophysiological evidence suggests that the highly unpleasant, bitter taste of a concentrated quinine hydrochloride (QHCL) should activate the human amygdala. In the present study, healthy subjects tasted 0.02 M QHCL or water while regional cerebral blood flow (rCBF) was assayed with H...

journal_title：Journal of neurophysiology

authors： Zald DH,Hagen MC,Pardo JV

更新日期：2002-02-01 00:00:00

abstract：:Long-term synaptic depression (LTD) of cerebellar parallel fiber-Purkinje cell synapses is a form of use-dependent synaptic plasticity that may be studied in cell culture. One form of LTD is induced postsynaptically through an mGlu1/Ca influx/protein kinase Cα (PKCα) cascade, and its initial expression requires phosph...

journal_title：Journal of neurophysiology

authors： Linden DJ

更新日期：2012-01-01 00:00:00

abstract：:Previous studies have demonstrated that locally administered cannabinoids attenuate allodynia and hyperalgesia through activation of peripheral cannabinoid receptors (CB(1) and CB(2)). However, it is currently unknown if cannabinoids alter the response properties of nociceptors. In the present study, correlative behav...

journal_title：Journal of neurophysiology

authors： Potenzieri C,Brink TS,Pacharinsak C,Simone DA

更新日期：2008-11-01 00:00:00

abstract：:1. Dopamine-containing neurons of the rat midbrain were recorded intracellularly in vitro. Anoxia (2-5 min) caused reversible membrane hyperpolarization (4-25 mV), which blocked spontaneous firing of action potentials. Under voltage clamp, anoxia produced an outward current (100-1,000 pA) associated with an increase i...

journal_title：Journal of neurophysiology

authors： Mercuri NB,Bonci A,Johnson SW,Stratta F,Calabresi P,Bernardi G

更新日期：1994-03-01 00:00:00

abstract：:The functional role of sensory input to the motor cortex was studied by interrupting two major input pathways. One was the dorsal column, which sends the input directly through the thalamus to the motor cortex, and the other was the sensory cortex, which transfers its input through association fibers. Removal of the s...

journal_title：Journal of neurophysiology

authors： Asanuma H,Arissian K

更新日期：1984-08-01 00:00:00

abstract：:Glutamate is the primary excitatory transmitter in axons innervating the hypothalamic suprachiasmatic nucleus (SCN) and is responsible for light-induced phase shifts of circadian rhythms generated by the SCN. By using self-innervating single neuron cultures and patch-clamp electrophysiology, we studied metabotropic gl...

journal_title：Journal of neurophysiology

authors： Chen G,van den Pol AN

更新日期：1998-10-01 00:00:00

abstract：:The orthodromic synaptic responses, membrane properties, and responses of dentate gyrus granule cells (DGCs) to several convulsant agents were studied in the in vitro hippocampal slice preparation. Orthodromic stimulation via the perforant pathway (PP) evoked excitatory-inhibitory postsynaptic potentials (EPSP-IPSP) s...

journal_title：Journal of neurophysiology

authors： Fricke RA,Prince DA

更新日期：1984-02-01 00:00:00

abstract：:Electrical transmission is a dynamically regulated form of communication and key to synchronizing neuronal activity. The bag cell neurons of Aplysia are a group of electrically coupled neuroendocrine cells that initiate ovulation by secreting egg-laying hormone during a prolonged period of synchronous firing called th...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Standage D,Groten CJ,Blohm G,Magoski NS

更新日期：2015-02-01 00:00:00

abstract：:Neurons in the medial superior olive (MSO) are tuned to the interaural time difference (ITD) of sound arriving at the two ears. MSO neurons evoke a strongest response at their best delay (BD), at which the internal delay between bilateral inputs to MSO matches the external ITD. We performed extracellular recordings in...

journal_title：Journal of neurophysiology

authors： Day ML,Semple MN

更新日期：2011-10-01 00:00:00

abstract：:The grip force applied to maintain grasp of a handheld object has been typically reported as tightly coupled to the load force exerted by the object as it is actively manipulated, occurring proportionally and consistently in phase with changes in load force. However, continuous grip force-load force coupling breaks do...

journal_title：Journal of neurophysiology

authors： Grover FM,Schwab SM,Silva PL,Lorenz T,Riley MA

更新日期：2019-12-01 00:00:00

abstract：:N-arachidonoyldopamine (NADA) is an endogenous molecule found in the nervous system that is capable of acting as a vanilloid agonist via the TRPV1 receptor and as a cannabinoid agonist via the CB1 receptor. Using anesthetized rats, we investigated the neural correlates of behavioral thermal hyperalgesia produced by NA...

journal_title：Journal of neurophysiology

authors： Huang SM,Walker JM

更新日期：2006-02-01 00:00:00

abstract：:Despite substantial advances in the field, particularly resulting from physiological studies in animals, the neural mechanisms underlying the generation of many motor behaviors in humans remain unclear. A recent study (Cappellini G et al. J Neurophysiol 104: 3064-3073, 2010) sheds more light on this topic. Like the st...

journal_title：Journal of neurophysiology

authors： Chiovetto E

更新日期：2011-04-01 00:00:00

abstract：:Hyperphagia is common in diabetes and may worsen hyperglycemia and diabetic complications. The responsible mechanisms are not well understood. The hypothalamus is a key center for the control of appetite and energy homeostasis. The ventromedial nucleus (VMH) and arcuate nucleus (ARC) are two critical nuclei involved i...

journal_title：Journal of neurophysiology

authors： Li JY,Wu X,Lee A,Zhou SY,Owyang C

更新日期：2019-03-01 00:00:00

abstract：:1. In cultured rat locus coeruleus neurons, somatostatin or met-enkephalin induces an inwardly rectifying K+ conductance. This inward rectifier was analyzed at the single-channel level. 2. Using the inside-out patch-clamp, guanosine 5'-triphosphate (GTP) application to the cytoplasmic side in the presence of somatosta...

journal_title：Journal of neurophysiology

authors： Grigg JJ,Kozasa T,Nakajima Y,Nakajima S

更新日期：1996-01-01 00:00:00

abstract：:We have used the rat hippocampal slice preparation as a model system for studying the epileptogenic consequences of a reduction in neuronal Na+-K+ pump activity. The cardiac glycosides (CGs) strophanthidin and dihydroouabain were used to inhibit the pump. These drugs had readily reversible effects, provided they were ...

journal_title：Journal of neurophysiology

authors： McCarren M,Alger BE

更新日期：1987-02-01 00:00:00

abstract：:When sudden environmental stimuli signaling threat occur in the portion of space surrounding the body (defensive peripersonal space), defensive responses are enhanced. Recently Bisio et al. (Bisio A, Garbarini F, Biggio M, Fossataro C, Ruggeri P, Bove M. J Neurosci 37: 2415-2424, 2017) showed that a marker of defensiv...

journal_title：Journal of neurophysiology

authors： Bufacchi RJ

更新日期：2017-10-01 00:00:00

abstract：:If a laterally displacing prism is placed in front of one eye of a person or monkey with the other eye occluded, they initially will point to one side of a target that is located directly in front of them. Normally, people and monkeys adapt easily to the displaced vision and correct their aim after a few trials. If th...

journal_title：Journal of neurophysiology

authors： Baizer JS,Kralj-Hans I,Glickstein M

更新日期：1999-04-01 00:00:00

abstract：:In this study, we examined the effect of arachidonic acid (AA) on the BK alpha-subunit with or without beta-subunits expressed in Xenopus oocytes. In excised patches, AA potentiated the hSlo-alpha current and slowed inactivation only when beta2/3 subunit was co-expressed. The beta2-subunit-dependent modulation by AA p...

journal_title：Journal of neurophysiology

authors： Sun X,Zhou D,Zhang P,Moczydlowski EG,Haddad GG

更新日期：2007-01-01 00:00:00

abstract：:Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radia...

journal_title：Journal of neurophysiology

authors： Klassen TL,Buckingham SD,Atherton DM,Dacks JB,Gallin WJ,Spencer AN

更新日期：2006-05-01 00:00:00

abstract：:Single-channel recording techniques were used to characterize mechanosensitive channels in identified (1.1'-dioctadecyl-3,3,3', 3'-tetramethylindocarbocyanine methanesulfonate labeled) colon sensory neurons dissociated from adult S1 dorsal root ganglia. Channels were found in 30% (7/23) of patches in a cell-attached c...

journal_title：Journal of neurophysiology

authors： Su X,Wachtel RE,Gebhart GF

更新日期：2000-08-01 00:00:00

abstract：:Speech stimuli give rise to neural activity in the listener that can be observed as waveforms using magnetoencephalography. Although waveforms vary greatly from trial to trial due to activity unrelated to the stimulus, it has been demonstrated that spoken sentences can be discriminated based on theta-band (3-7 Hz) pha...

journal_title：Journal of neurophysiology

authors： Howard MF,Poeppel D

更新日期：2010-11-01 00:00:00

abstract：:Although G-protein-coupled (metabotropic) receptors are known to modulate the production of motor patterns, evidence from the escape swim central pattern generator (CPG) of the nudibranch mollusk, Tritonia diomedea, suggests that they might also participate in the generation of the motor pattern itself. The dorsal swi...

journal_title：Journal of neurophysiology

authors： Clemens S,Katz PS

更新日期：2001-01-01 00:00:00

abstract：:1. We examined the role of gamma-aminobutyric acid (GABA)-mediated inhibition in shaping excitatory tuning curves and creating selectivity for frequency-modulated (FM) sweeps in 29 neurons in the central nucleus of the inferior colliculus (ICC) of the pallid bat, with the use of single-unit recording coupled with the ...

journal_title：Journal of neurophysiology

authors： Fuzessery ZM,Hall JC

更新日期：1996-08-01 00:00:00

abstract：:1. Intracellular recordings near the output terminals of an identified interneuron (the descending contralateral movement detector, DCMD) in the locust revealed the occurrence of depolarizing synaptic potentials. These presynaptic depolarizing potentials were evoked by spikes in both DCMDs, by auditory stimuli, and by...

journal_title：Journal of neurophysiology

authors： Pearson KG,Goodman CS

更新日期：1981-03-01 00:00:00

abstract：:The mechanical actions of various ankle muscles were changed by surgically crossing or transferring the tendons in kittens. After the kittens grew to adults, both hindlimbs were implanted with multiple electromyogram (EMG) recording and cutaneous nerve stimulation electrodes to compare the activity of altered and norm...

journal_title：Journal of neurophysiology

authors： Loeb GE

更新日期：1999-12-01 00:00:00