Slow brain potential and oscillatory EEG manifestations of impaired temporal preparation in Parkinson's disease.

abstract：:Gene delivery to the primate central nervous system via recombinant adeno-associated viral vectors (AAV) allows neurophysiologists to control and observe neural activity precisely. A current limitation of this approach is variability in vector transduction efficiency. Low levels of transduction can foil experimental m...

journal_title：Journal of neurophysiology

authors： Mendoza SD,El-Shamayleh Y,Horwitz GD

更新日期：2017-05-01 00:00:00

abstract：:Adaptive processes are crucial in maintaining the accuracy of body movements and rely on error storage and processing mechanisms. Although classically studied with adaptation paradigms, evidence of these ongoing error-correction mechanisms should also be detectable in other movements. Despite this connection, current ...

journal_title：Journal of neurophysiology

authors： Wong AL,Shelhamer M

更新日期：2014-05-01 00:00:00

abstract：:1. The selectivity of adaptation to unidirectional motion was examined in neurons of the cat striate cortex. Following prolonged stimulation with a unidirectional high-contrast grating, the responsivity of cortical neurons was reduced. In many units this decrease was restricted to the direction of prior stimulation. T...

journal_title：Journal of neurophysiology

authors： Marlin SG,Hasan SJ,Cynader MS

更新日期：1988-04-01 00:00:00

abstract：:1. The retinotopic organization of retinal inputs from the lateral eye of Limulus to the optic ganglia of the brain was determined from microelectrode recordings of nerve impulses. 2. The central connections of the natural subunits of the lateral optic nerve were determined using cobalt impregnation of cut axons. 3. C...

journal_title：Journal of neurophysiology

authors： Chamberlain SC,Barlow RB Jr

更新日期：1982-08-01 00:00:00

abstract：:The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the exclusive relay of retinal information en route to the visual cortex. Although much of our understanding about dLGN comes from studies done in higher mammals, such as the cat and primate, the mouse as a model organism has moved to the forefront as a t...

journal_title：Journal of neurophysiology

authors： Guido W

更新日期：2018-07-01 00:00:00

abstract：:Normative theories posit that value-based decision-making is context independent. However, decisions between two high-value options can be suboptimally biased by the introduction of a third low-value option. This context-dependent modulation is consistent with the divisive normalization of the value of each stimulus b...

journal_title：Journal of neurophysiology

authors： Itthipuripat S,Cha K,Rangsipat N,Serences JT

更新日期：2015-07-01 00:00:00

abstract：:An increase in L-arginine hemolymph concentration acts as a postingestion signal inhibiting Aplysia feeding. At physiological concentrations (a 10-μM increase over background), the inhibitory effect of L-arginine is too weak to block feeding in hungry animals. However, a 10-μM increase in L-arginine concentration acts...

journal_title：Journal of neurophysiology

authors： Miller N,Saada R,Markovich S,Hurwitz I,Susswein AJ

更新日期：2011-04-01 00:00:00

abstract：:1. Single-electrode voltage-clamp recordings were made from CA3 pyramidal cells in organotypic hippocampal slice cultures for measurement of membrane currents underlying both the gamma-aminobutyric acid (GABA)-mediated, Cl- -dependent inhibitory postsynaptic potential (IPSC), evoked in response to stimulation of the m...

journal_title：Journal of neurophysiology

authors： Thompson SM,Gähwiler BH

更新日期：1989-03-01 00:00:00

abstract：:Endocannabinoids are lipid derivatives that mediate paracrine and juxtacrine signaling between cells. In the hippocampal CA1 region, a retrograde endocannabinoid signal suppresses GABA release by acting on presynaptic cannabinoid receptor-1 (CB1) and can be functionally manifested as depolarization-induced suppression...

journal_title：Journal of neurophysiology

authors： Zhu PJ,Lovinger DM

更新日期：2010-02-01 00:00:00

abstract：:Compression apparel is popular in both medical and sport performance settings. Perceived benefits are suggested to include changes in sensory feedback transmission caused by activation of mechanoreceptors. However, little is known about effects of compression apparel on sensorimotor control. Our purpose was to mechani...

journal_title：Journal of neurophysiology

authors： Barss TS,Pearcey GEP,Munro B,Bishop JL,Zehr EP

更新日期：2018-07-01 00:00:00

abstract：:1. Intracellular recordings were made from layer VI pyramidal cells in in vitro slice preparations of the cat motor cortex (area 4 gamma). Layer VI pyramidal cells were identified morphologically by intracellular injection of biocytin. 2. Of 22 layer VI pyramidal cells examined, single action potentials were followed ...

journal_title：Journal of neurophysiology

authors： Kang Y,Kayano F

更新日期：1994-08-01 00:00:00

abstract：:Spontaneous and stimulus-evoked excitatory postsynaptic currents (EPSCs) were recorded in calyx nerve terminals from the turtle vestibular lagena to quantify key attributes of quantal transmission at this synapse. On average, EPSC events had a magnitude of ∼ 42 pA, a rise time constant of τ(0) ∼ 229 μs, decayed to bas...

journal_title：Journal of neurophysiology

authors： Highstein SM,Mann MA,Holstein GR,Rabbitt RD

更新日期：2015-06-01 00:00:00

abstract：:A total of 51 dorsal horn units responsive to heat were isolated and their receptive fields characterized (i.e., response properties and adequate stimuli determined) in pentobarbital-anesthetized, paralyzed rats. In 39 of the 51 units, the descending inhibition of heat-evoked activity produced by focal electrical stim...

journal_title：Journal of neurophysiology

authors： Jones SL,Gebhart GF

更新日期：1986-11-01 00:00:00

abstract：:Moth pheromones cause rises in intracellular Ca(2+) concentrations that activate Ca(2+)-dependent cation channels in antennal olfactory receptor neurons. In addition, mechanisms of adaptation and sensitization depend on changes in cyclic nucleotide concentrations. Here, cyclic nucleotide-activated currents in cultured...

journal_title：Journal of neurophysiology

authors： Krannich S,Stengl M

更新日期：2008-11-01 00:00:00

abstract：:Corneal-responsive neurons were recorded extracellularly in two regions of the spinal trigeminal nucleus, subnucleus interpolaris/caudalis (Vi/Vc) and subnucleus caudalis/upper cervical cord (Vc/C1) transition regions, from methohexital-anesthetized male rats. Thirty-nine Vi/Vc and 26 Vc/C1 neurons that responded to m...

journal_title：Journal of neurophysiology

authors： Hirata H,Hu JW,Bereiter DA

更新日期：1999-11-01 00:00:00

abstract：:The aim of this study was to determine whether neuronal activity in the macaque supplementary eye field (SEF) is influenced by the rule used for saccadic target selection. Two monkeys were trained to perform a variant of the memory-guided saccade task in which any of four visible dots (rightward, upward, leftward, and...

journal_title：Journal of neurophysiology

authors： Olson CR,Gettner SN,Ventura V,Carta R,Kass RE

更新日期：2000-09-01 00:00:00

abstract：:The rapid detection of sensory inputs is crucial for survival. Sensory detection explicitly requires the integration of incoming sensory information and the ability to distinguish between relevant information and ongoing neural activity. In this study, head-fixed rats were trained to detect the presence of a brief def...

journal_title：Journal of neurophysiology

authors： Ollerenshaw DR,Bari BA,Millard DC,Orr LE,Wang Q,Stanley GB

更新日期：2012-07-01 00:00:00

abstract：:1. Whole cell patch-clamp techniques, combined with direct visualization of neurons, were used to study voltage-dependent potassium currents in layer 1 neurons and layer II/III pyramidal cells. 2. In the presence of tetrodotoxin, step depolarizations evoked an outward current. This current had a complex waveform and a...

journal_title：Journal of neurophysiology

authors： Zhou FM,Hablitz JJ

更新日期：1996-08-01 00:00:00

abstract：:The superior colliculus (SC) provides signals for the generation of saccades via a direct pathway to the brain stem burst generator (BG). In addition, it sends saccade-related activity to the BG indirectly through the cerebellum via a relay in the nucleus reticularis tegmenti pontis (NRTP). Lesions of the oculomotor v...

journal_title：Journal of neurophysiology

authors： Kaneko CR,Fuchs AF

更新日期：2006-06-01 00:00:00

abstract：:1. The little brown bat, Myotis lucifugus, employs biosonar pulses containing broadband frequency-modulated (FM) sounds of only one harmonic during the initial phases of echolocation. Neurons throughout the auditory cortex exhibit delay-dependent facilitation to artificial pulses and echoes at particular echo delays. ...

journal_title：Journal of neurophysiology

authors： Paschal WG,Wong D

更新日期：1994-07-01 00:00:00

abstract：:1. Areas of cerebellar cortex related to saccadic eye movements were ablated in three Macaca mulatta monkeys trained to fixate visual targets. There followed a postoperative dysmetria of saccadic eye movements which appeared to be the result of an impairment specifically within the saccadic system. 2. Convergent evide...

journal_title：Journal of neurophysiology

authors： Ritchie L

更新日期：1976-11-01 00:00:00

abstract：:N-Acetylaspartylglutamate (NAAG) is an agonist at the type 3 metabotropic glutamate receptor (mGluR3), which is coupled to a Gi/o protein. When activated, the mGluR3 receptor inhibits adenylyl cyclase and reduces the cAMP-mediated second-messenger cascade. Long-term potentiation (LTP) in the medial perforant path (MPP...

journal_title：Journal of neurophysiology

authors： Lea PM 4th,Wroblewska B,Sarvey JM,Neale JH

更新日期：2001-03-01 00:00:00

abstract：:Motor performance induces a postexercise increase in corticomotor excitability that may be associated with motor learning. We investigated whether there are hemispheric differences in the extent and/or time course of changes in corticomotor excitability following a manipulation task (Purdue pegboard) and their relatio...

journal_title：Journal of neurophysiology

authors： Garry MI,Kamen G,Nordstrom MA

更新日期：2004-04-01 00:00:00

abstract：:The effect of acute intrahippocampal infusion of brain-derived neurotrophic factor (BDNF) on synaptic transmission in the dentate gyrus was investigated in urethan-anesthetized rats. Medial perforant path-evoked field potentials were recorded in the dentate hilus and BDNF-containing buffer was infused (4 microl, 25 mi...

journal_title：Journal of neurophysiology

authors： Messaoudi E,Bârdsen K,Srebro B,Bramham CR

更新日期：1998-01-01 00:00:00

abstract：:Tissue injury in early life can produce distinctive effects on pain processing, but little is known about the underlying neural mechanisms. Neonatal inflammation modulates excitatory synapses in spinal nociceptive circuits, but it is unclear whether this results directly from altered afferent input. Here we investigat...

journal_title：Journal of neurophysiology

authors： Li J,Walker SM,Fitzgerald M,Baccei ML

更新日期：2009-10-01 00:00:00

abstract：:Based on the findings of the preceding paper, it is known that auditory and visual signals have been translated into common coordinates at the level of the superior colliculus (SC) and share a motor circuit involved in the generation of saccadic eye movements. It is not known, however, whether the translation of senso...

journal_title：Journal of neurophysiology

authors： Jay MF,Sparks DL

更新日期：1987-01-01 00:00:00

abstract：:Voluntary and stimulus-driven shifts of attention can modulate the representation of behaviorally relevant stimuli in early areas of visual cortex. In turn, attended items are processed faster and more accurately, facilitating the selection of appropriate behavioral responses. Information processing is also strongly i...

journal_title：Journal of neurophysiology

authors： Serences JT,Saproo S

更新日期：2010-07-01 00:00:00

abstract：:Ifenprodil is a selective blocker of NMDA receptors that are heterodimers composed of GluN1/GluN2B subunits. This pharmacological profile has been extensively used to test the role of GluN2B-containing NMDA receptors in learning and memory formation. However, ifenprodil has also been reported to have actions at a numb...

journal_title：Journal of neurophysiology

authors： Delaney AJ,Power JM,Sah P

更新日期：2012-03-01 00:00:00

abstract：:Recent work has investigated the link between motor learning and sensory function in arm movement control. A number of findings are consistent with the idea that motor learning is associated with systematic changes to proprioception (Haith A, Jackson C, Mial R, Vijayakumar S. Adv Neural Inf Process Syst 21: 593-600, 2...

journal_title：Journal of neurophysiology

authors： Wong JD,Kistemaker DA,Chin A,Gribble PL

更新日期：2012-12-01 00:00:00

abstract：:How the CNS masters the many degrees of freedom of the musculoskeletal system to control goal-directed movements is a long-standing question. We have recently provided support to the hypothesis that the CNS relies on a modular control architecture by showing that the phasic muscle patterns for fast reaching movements ...

journal_title：Journal of neurophysiology

authors： d'Avella A,Fernandez L,Portone A,Lacquaniti F

更新日期：2008-09-01 00:00:00