Functional CB1 receptors are broadly expressed in neocortical GABAergic and glutamatergic neurons.

abstract：:It has been shown that tetanic stimulation of area 2 of the somatosensory cortex produces long-term potentiation in neurons in area 4gamma, and this has been suggested as the basis of learning new motor skills. The purpose of this study was to further elucidate the characteristics of this projection by the use of evok...

journal_title：Journal of neurophysiology

authors： Caria MA,Kaneko T,Kimura A,Asanuma H

更新日期：1997-06-01 00:00:00

abstract：:In experiments on slices (from 100- to 150-g Sprague-Dawley rats) kept at 33 degreesC, we studied the effects of brief hypoxia (2-3 min) on CA1 neurons. In whole cell recordings from submerged slices, with electrodes containing only KMeSO4 and N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, and in the presence of...

journal_title：Journal of neurophysiology

authors： Erdemli G,Xu YZ,Krnjević K

更新日期：1998-11-01 00:00:00

abstract：:1. H reflexes were elicited in the second interosseous muscle of the hindpaw of the anesthetized dog during passive rotation of the shank about the ipsilateral or contralateral knee. Reflexes sampled at four points in the cycle of movement were compared with stationary controls. For both the ipsilateral and contralate...

journal_title：Journal of neurophysiology

authors： Misiaszek JE,Barclay JK,Brooke JD

更新日期：1996-11-01 00:00:00

abstract：:To characterize spike coding in spinal neurons during rhythmic locomotor activity, we recorded from individual cells in the lumbar spinal cord of neonatal rats by using the on-cell patch-clamp technique. Locomotor activity was induced by N-methyl-D aspartate (NMDA) and 5-hydroxytryptamine (5-HT) and monitored by ventr...

journal_title：Journal of neurophysiology

authors： Raastad M,Kiehn O

更新日期：2000-05-01 00:00:00

abstract：:1. The intersegmental coordination during undulatory locomotion in lamprey is characterized by a constant phase lag between consecutive segments, that is, the ratio between the intersegmental time lag and the cycle duration remains constant. It is shown that the spinal 5-HT (serotonin) system can, in a graded fashion,...

journal_title：Journal of neurophysiology

authors： Matsushima T,Grillner S

更新日期：1992-06-01 00:00:00

abstract：:During locomotion, contacting an obstacle generates a coordinated response involving flexion of the stimulated leg and activation of extensors contralaterally to ensure adequate support and forward progression. Activation of motoneurons innervating contralateral muscles (i.e., crossed extensor reflex) has always been ...

journal_title：Journal of neurophysiology

authors： Frigon A,Rossignol S

更新日期：2008-02-01 00:00:00

abstract：:1. The sensorimotor synapse of Aplysia expresses various shortlasting changes in synaptic efficacy including homosynaptic depression (HSD) and heterosynaptic facilitation by serotonin (5-HT) either at nondepressed sensory neuron (SN) synaptic connections or at SN synaptic connections first depressed by HSD. We examine...

journal_title：Journal of neurophysiology

authors： Sun ZY,Schacher S

更新日期：1996-10-01 00:00:00

abstract：:Sopite syndrome, centered around the drowsiness, lethargy, and irritability associated with motion sickness, can be induced by exposure to low-frequency motion. It is known that the vestibular apparatus plays an important role in the pathogenesis of motion sickness, which features several autonomic responses, and we h...

journal_title：Journal of neurophysiology

authors： Foster M,Singh N,Kwok K,Macefield VG

更新日期：2020-12-01 00:00:00

abstract：:1. Patch-clamp methods were used to study recombinant glutamate receptor (GluR) ion channels expressed in human embryonic kidney cells (HEK 293) after transfection of the cells with cDNAs encoding kainate (KA)-type GluR subunits. Cells were transiently or stably transfected with the fully edited (R) version of GluR6 o...

journal_title：Journal of neurophysiology

authors： Howe JR

更新日期：1996-07-01 00:00:00

abstract：:Ion channel modulation by the peptide myomodulin (MM) has been demonstrated in a wide variety of organisms including Aplysia, Lymnaea, and Pleurobranchaea. This neural and muscular modulation has been shown to be important for shaping and modifying behavior. In this paper, we report that MM modulates several distinct ...

journal_title：Journal of neurophysiology

authors： Wang Y,Strong JA,Sahley CL

更新日期：1999-07-01 00:00:00

abstract：:Changes to cerebral miRNA expression have been implicated in the progression of Alzheimer's disease (AD), as miRNAs that regulate the expression of gene products involved in amyloid beta (Aβ) processing, such as BACE1, are dysregulated in those that suffer from AD. Exercise training improves cognition and reduces BACE...

journal_title：Journal of neurophysiology

authors： Dungan CM,Valentino T,Vechetti IJ Jr,Zdunek CJ,Murphy MP,Lin AL,McCarthy JJ,Peterson CA

更新日期：2020-12-01 00:00:00

abstract：:Action-potential propagation into the axon terminals of olfactory receptor cells was measured with the use of voltage-sensitive dye imaging in the isolated spiny lobster brain. Conditioning shocks to the olfactory nerve, known to cause long-lasting suppression of olfactory lobe neurons, allowed the selective imaging o...

journal_title：Journal of neurophysiology

authors： Wachowiak M,Cohen LB

更新日期：1998-08-01 00:00:00

abstract：:1. The modulation of reflex responses in up to 10 simultaneously recorded hindlimb muscles was studied in unrestrained cats walking on a treadmill. Single electrical shocks of various strengths were applied to different skin areas of teh hindlimb at different times of the step cycle while the resulting EMG responses w...

journal_title：Journal of neurophysiology

authors： Duysens J,Loeb GE

更新日期：1980-11-01 00:00:00

abstract：:We asked if the information about stimulus motion used in a visual working-memory task is localized in space. Monkeys compared the directions of two moving random-dot stimuli, sample and test, separated by a temporal delay and reported whether the stimuli moved in the same or in different directions. By presenting the...

journal_title：Journal of neurophysiology

authors： Zaksas D,Bisley JW,Pasternak T

更新日期：2001-08-01 00:00:00

abstract：:Our perception of the positions of objects in our surroundings is surprisingly unaffected by movements of the eyes, head, and body. This suggests that the brain has a mechanism for maintaining perceptual stability, based either on the spatial relationships among visible objects or internal copies of its own motor comm...

journal_title：Journal of neurophysiology

authors： Churan J,Guitton D,Pack CC

更新日期：2011-10-01 00:00:00

abstract：:Hyolaryngeal elevation is essential for airway protection during swallowing and is mainly a reflexive response to oropharyngeal sensory stimulation. Targeted intramuscular electrical stimulation can elevate the resting larynx and, if applied during swallowing, may improve airway protection in dysphagic patients with i...

journal_title：Journal of neurophysiology

authors： Burnett TA,Mann EA,Stoklosa JB,Ludlow CL

更新日期：2005-12-01 00:00:00

abstract：:Contrast thresholds for detection of stationary and flickering gratings were measured behaviorally for each eye of cats raised with induced convergent strabismus. The performance of the deviating eye was inferior to that of the nondeviating eye when test patterns were stationary. Flicker served to reduce the performan...

journal_title：Journal of neurophysiology

authors： Holopigian K,Blake R

更新日期：1983-07-01 00:00:00

abstract：:The nucleus gracilis (NG) receives an abundance of visceral input from various abdominal organs and is proposed to play an important role in visceral pain processing. The purpose of this study was to investigate the necessity of the NG for colorectal input into the ventral posterolateral (VPL) nucleus of the thalamus....

journal_title：Journal of neurophysiology

authors： Al-Chaer ED,Westlund KN,Willis WD

更新日期：1997-07-01 00:00:00

abstract：:Neural oscillations are observed ubiquitously in the mammalian brain, but their stability is known to be rather variable. Some oscillations are tonic and last for seconds or even minutes. Other oscillations appear as unstable bursts. Likewise, some oscillations rely on excitatory AMPAergic synapses, but others are GAB...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Voytek B

更新日期：2020-07-01 00:00:00

abstract：:We examined which motor areas would participate in the coding of a simple opposition of the thumb triggered by auditory, somatosensory and visual signals. We tested which motor areas might be active in response to all three modalities, which motor structures would be activated specifically in response to each modality...

journal_title：Journal of neurophysiology

authors： Naito E,Kinomura S,Geyer S,Kawashima R,Roland PE,Zilles K

更新日期：2000-03-01 00:00:00

abstract：:Iontophoresis of glutamate at sites on the apical dendrite 278-555 microm from the somata of rat neocortical pyramidal neurons evoked low-threshold, small, slow spikes and/or large, fast spikes in 71% of recorded cells. The amplitude of the small, slow spikes recorded at the soma averaged 9.1 mV, and their apparent th...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1997-05-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00

abstract：:1. Current- and voltage-clamp studies were conducted on isolated rat adrenal chromaffin cells to identify the voltage-dependent ion channels mediating inward currents. 2. Mean resting membrane potential of the isolated cells was -62 +/- 3 (SE) mV. Evoked action potentials were both Na+ and Ca2+ based, and whole cell v...

journal_title：Journal of neurophysiology

authors： Hollins B,Ikeda SR

更新日期：1996-08-01 00:00:00

abstract：:1. Inhibitors of extracellular carbonic anhydrase (CAo) offer much promise as diagnostic tools in the study of the synaptic basis of activity-induced alkaline transients in the brain. However, most of the present information related to the effects of CAo blockers in nervous tissue comes from experiments that involve s...

journal_title：Journal of neurophysiology

authors： Voipio J,Paalasmaa P,Taira T,Kaila K

更新日期：1995-08-01 00:00:00

abstract：:A desirable goal of functional MRI (fMRI), both clinically and for basic research, is to produce detailed maps of cortical function in individual subjects. Single-subject mapping of the somatotopic hand representation in the human primary somatosensory cortex (S1) has been performed using both phase-encoding and block...

journal_title：Journal of neurophysiology

authors： Besle J,Sánchez-Panchuelo RM,Bowtell R,Francis S,Schluppeck D

更新日期：2013-05-01 00:00:00

abstract：:1. Whole cell patch-clamp recordings were made of low-voltage-activated (LVA) calcium (Ca2+) currents using 2 mM barium (Ba2+) as charge carrier. Acutely dissociated neurons from medial septum (MS) and the nucleus of the diagonal band (nDB) were examined in young adult (1-3 mo) and aged (24-26 mo) Fischer 344 rats. 2....

journal_title：Journal of neurophysiology

authors： Murchison D,Griffith WH

更新日期：1995-08-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:Apical dendrites of layer 5 pyramidal cells in a slice preparation of rat sensorimotor cortex were depolarized focally by long-lasting glutamate iontophoresis while recording intracellularly from their soma. In most cells the firing pattern evoked by the smallest dendritic depolarization that evoked spikes consisted o...

journal_title：Journal of neurophysiology

authors： Schwindt P,Crill W

更新日期：1999-03-01 00:00:00

abstract：:The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...

journal_title：Journal of neurophysiology

authors： Zayachkivsky A,Lehmkuhle MJ,Ekstrand JJ,Dudek FE

更新日期：2015-11-01 00:00:00

abstract：:A previous neurophysiological investigation demonstrated an increase in functional projections of expiratory bulbospinal neurons (EBSNs) in the segment above a chronic lateral thoracic spinal cord lesion that severed their axons. We have now investigated how this plasticity might be manifested in thoracic motoneurons ...

journal_title：Journal of neurophysiology

authors： Ford TW,Anissimova NP,Meehan CF,Kirkwood PA

更新日期：2016-01-01 00:00:00