Activation of GIRK channels by muscarinic receptors and group II metabotropic glutamate receptors suppresses Golgi cell activity in the cochlear nucleus of mice.

abstract：:1. Whole cell patch-clamp techniques, combined with direct visualization of neurons, were used to study voltage-dependent potassium currents in layer 1 neurons and layer II/III pyramidal cells. 2. In the presence of tetrodotoxin, step depolarizations evoked an outward current. This current had a complex waveform and a...

journal_title：Journal of neurophysiology

authors： Zhou FM,Hablitz JJ

更新日期：1996-08-01 00:00:00

abstract：:Glutamate-receptor-mediated synaptic transmission was studied in morphologically identified hippocampal dentate granule cells (DGCs; n = 31) with the use of whole cell patch-clamp recording and intracellular injection of biocytin or Lucifer yellow in slices prepared from surgically removed medial temporal lobe specime...

journal_title：Journal of neurophysiology

authors： Isokawa M,Levesque M,Fried I,Engel J Jr

更新日期：1997-06-01 00:00:00

abstract：:In adults, locomotor movements are accommodated to various support surface conditions by means of specific anticipatory locomotor adjustments and changes in the intersegmental coordination. Here we studied the kinematic strategies of toddlers at the onset of independent walking when negotiating various support surface...

journal_title：Journal of neurophysiology

authors： Dominici N,Ivanenko YP,Cappellini G,Zampagni ML,Lacquaniti F

更新日期：2010-03-01 00:00:00

abstract：:Cell-surface glutamate transporters are essential for the proper function of early cortical networks because their dysfunction induces seizures in the newborn rat in vivo. We have now analyzed the consequences of their inhibition by DL-TBOA on the activity of the developing CA1 rat hippocampal network in vitro. DL-TBO...

journal_title：Journal of neurophysiology

authors： Cattani AA,Bonfardin VD,Represa A,Ben-Ari Y,Aniksztejn L

更新日期：2007-10-01 00:00:00

abstract：:1. The selectivity of adaptation to unidirectional motion was examined in neurons of the cat striate cortex. Following prolonged stimulation with a unidirectional high-contrast grating, the responsivity of cortical neurons was reduced. In many units this decrease was restricted to the direction of prior stimulation. T...

journal_title：Journal of neurophysiology

authors： Marlin SG,Hasan SJ,Cynader MS

更新日期：1988-04-01 00:00:00

abstract：:Damage to the cerebellum causes characteristic movement abnormalities but is thought to have minimal impact on somatosensory perception. Traditional clinical assessments of patients with cerebellar lesions reveal no perceptual deficits despite the fact that the cerebellum receives substantial somatosensory information...

journal_title：Journal of neurophysiology

authors： Bhanpuri NH,Okamura AM,Bastian AJ

更新日期：2012-03-01 00:00:00

abstract：:The ventral nucleus of the lateral lemniscus (VNLL) is a major auditory nucleus that sends a large projection to the inferior colliculus. Despite its prominence, the responses of neurons in the VNLL have not been extensively studied. Previous studies in nonecholocating species have used anesthesia, which is known to a...

journal_title：Journal of neurophysiology

authors： Batra R,Fitzpatrick DC

更新日期：1999-09-01 00:00:00

abstract：:The brain's ability to integrate information from different senses is acquired only after extensive sensory experience. However, whether early life experience instantiates a general integrative capacity in multisensory neurons or one limited to the particular cross-modal stimulus combinations to which one has been exp...

journal_title：Journal of neurophysiology

authors： Xu J,Yu L,Stanford TR,Rowland BA,Stein BE

更新日期：2015-02-01 00:00:00

abstract：:Gene delivery to the primate central nervous system via recombinant adeno-associated viral vectors (AAV) allows neurophysiologists to control and observe neural activity precisely. A current limitation of this approach is variability in vector transduction efficiency. Low levels of transduction can foil experimental m...

journal_title：Journal of neurophysiology

authors： Mendoza SD,El-Shamayleh Y,Horwitz GD

更新日期：2017-05-01 00:00:00

abstract：:Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radia...

journal_title：Journal of neurophysiology

authors： Klassen TL,Buckingham SD,Atherton DM,Dacks JB,Gallin WJ,Spencer AN

更新日期：2006-05-01 00:00:00

abstract：:We demonstrate distinct α- (7-14 Hz) and β-band (15-30 Hz) rhythms in rat somatosensory cortex in vivo using epidural electrocorticography recordings. Moreover, we show in rats that a genuine β-rhythm coexists alongside β-activity that reflects the second harmonic of the arch-shaped somatosensory α-rhythm. This demons...

journal_title：Journal of neurophysiology

authors： Fransen AM,Dimitriadis G,van Ede F,Maris E

更新日期：2016-06-01 00:00:00

abstract：:1. The primary functions of the superior colliculus (SC) are thought to include both the spatial localization of sensory stimuli and the initiation of an orienting response. It has been hypothesized that, in cat, both of these SC functions may be influenced by feedback from the extraocular muscles. The present investi...

journal_title：Journal of neurophysiology

authors： Nelson JS,Meredith MA,Stein BE

更新日期：1989-12-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) are comprised of different subunits. NR2 subunits confer different pharmacological and biophysical properties to NMDARs. Although NR2B subunit expression is uniform throughout striatum, NR2A subunit expression is greater laterally. Pharmacologically isolated NMDAR-mediated excit...

journal_title：Journal of neurophysiology

authors： Chapman DE,Keefe KA,Wilcox KS

更新日期：2003-01-01 00:00:00

abstract：:The lateral hypothalamus (LH) and the central nucleus of the amygdala (CeA) exert an influence on ingestive behavior and are reciprocally connected to gustatory and viscerosensory areas, including the nucleus of the solitary tract (NST) and the parabrachial nuclei (PbN). We investigated the effects of LH and CeA stimu...

journal_title：Journal of neurophysiology

authors： Li CS,Cho YK,Smith DV

更新日期：2005-03-01 00:00:00

abstract：:Using microstimulation to imprint meaningful activity patterns into intrinsically highly interconnected neuronal substrates is hampered by activation of fibers of passage leading to a spatiotemporal "blur" of activity. The focus of the present study was to characterize the shape of this blur in the neocortex to arrive...

journal_title：Journal of neurophysiology

authors： Butovas S,Schwarz C

更新日期：2003-11-01 00:00:00

abstract：:Perceptual decision making is often modeled as perfect integration of sequential sensory samples until the accumulated total reaches a fixed decision bound. In that view, the buildup of neural activity during perceptual decision making is attributed to temporal integration. However, an alternative explanation is that ...

journal_title：Journal of neurophysiology

authors： Carland MA,Marcos E,Thura D,Cisek P

更新日期：2016-02-01 00:00:00

abstract：:Extracellular discharges from single neurons in the internal segment of the globus pallidus (GPi) were recorded and analyzed for rate changes associated with visually guided forearm rotations to four different targets. We sought to examine how GPi neurons contribute to movement preparation and execution. Unit discharg...

journal_title：Journal of neurophysiology

authors： Gdowski MJ,Miller LE,Parrish T,Nenonene EK,Houk JC

更新日期：2001-02-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00

abstract：:High-frequency burstlike electrical conditioning stimulation (HFS) applied to human skin induces an increase in mechanical pinprick sensitivity of the surrounding unconditioned skin (a phenomenon known as secondary hyperalgesia). The present study assessed the effect of frequency of conditioning stimulation on the dev...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Gousset S,Bouvy J,Stouffs A,Lebrun L,van Neerven SGA,Mouraux A

更新日期：2019-09-01 00:00:00

abstract：:1. Using patch-clamp recordings, expression of voltage-activated ion channels by identified glial cells in situ was studied in hippocampal slices derived from 5- to 24-day-old rats. Glial cells were filled with Lucifer yellow during recording, and were identified by staining for glial fibrillary acidic protein (GFAP)....

journal_title：Journal of neurophysiology

authors： Sontheimer H,Waxman SG

更新日期：1993-11-01 00:00:00

abstract：:1. Single-unit and multiunit activities were recorded at the area 17-18 border of each cortical hemisphere in paralyzed cats anesthetized with nitrous oxide supplemented with halothane. Cross-correlation histograms (CCHs) were computed between 86 pairs of single units and 99 pairs of multiunit activities. Visually evo...

journal_title：Journal of neurophysiology

authors： Nowak LG,Munk MH,Nelson JI,James AC,Bullier J

更新日期：1995-12-01 00:00:00

abstract：:Abductor hallucis is the largest muscle in the arch of the human foot and comprises few motor units relative to its physiological cross-sectional area. It has been described as a postural muscle, aiding in the stabilization of the longitudinal arch during stance and gait. The purpose of this study was to describe the ...

journal_title：Journal of neurophysiology

authors： Kelly LA,Racinais S,Cresswell AG

更新日期：2013-08-01 00:00:00

abstract：:The ablation of afferent input results in the reorganization of sensory and motor cortices. In the primary visual cortex (V1), binocular retinal lesions deprive a corresponding cortical region [lesion projection zone (LPZ)] of visual input. Nevertheless, neurons in the LPZ regain responsiveness by shifting their recep...

journal_title：Journal of neurophysiology

authors： McManus JN,Ullman S,Gilbert CD

更新日期：2008-05-01 00:00:00

abstract：:A series of studies were carried out to investigate the role of the cerebellar flocculus and ventral paraflocculus in the ability to voluntarily cancel the vestibuloocular reflex (VOR). Squirrel monkeys were trained to pursue moving visual targets and to fixate a head stationary or earth stationary target during passi...

journal_title：Journal of neurophysiology

authors： Belton T,McCrea RA

更新日期：2000-09-01 00:00:00

abstract：:Visual input provides vital information for helping us modify our walking pattern. For example, artificial optic flow can drive changes in step length during locomotion and may also be useful for augmenting locomotor training for individuals with gait asymmetries. Here we asked whether optic flow could modify the acqu...

journal_title：Journal of neurophysiology

authors： Finley JM,Statton MA,Bastian AJ

更新日期：2014-03-01 00:00:00

abstract：:1. The properties of parietal neurons were studied in four adult rhesus monkeys during fast arm movements. The animals were trained to perform flexion or extension of the forearm about the elbow in response to specific auditory cues. Single neuron activity was recorded in 272 area 5 neurons, 81 neurons of the somatose...

journal_title：Journal of neurophysiology

authors： Burbaud P,Doegle C,Gross C,Bioulac B

更新日期：1991-08-01 00:00:00

abstract：:Regulation of feeding behavior involves the integration of multiple physiological and neurological pathways that control both nutrient-seeking and consummatory behaviors. The consummatory phase of ingestion includes stereotyped oromotor movements of the tongue and jaw that are controlled through brain stem pathways. T...

journal_title：Journal of neurophysiology

authors： Nasse JS,Travers JB

更新日期：2014-08-01 00:00:00

abstract：:Reach-to-grasp movements require information about the distance and size of target objects. Calibration of this information could be achieved via feedback information (visual and/or haptic) regarding terminal accuracy when target objects are grasped. A number of reports suggest that the nervous system alters reach-to-...

journal_title：Journal of neurophysiology

authors： Bingham GP,Mon-Williams MA

更新日期：2013-12-01 00:00:00

abstract：:1. This paper examines the electrophysiological properties of cultured rat adrenal chromaffin cells at different stages of neuron-like morphological differentiation in response to nerve growth factor (NGF). 2. Chromaffin cells display a large variability in the morphological changes after exposure to NGF. However, a m...

journal_title：Journal of neurophysiology

authors： Islas-Suárez L,Gómez-Chavarín M,Drucker-Colín R,Hernández-Cruz A

更新日期：1994-10-01 00:00:00

abstract：:Single-unit activity was recorded from the caudate nucleus (CD), globus pallidus, and entopeduncular nucleus (GP-ENTO) in awake, partially restrained kittens. The purpose of this experiment was to assess the ability of developing basal ganglia structures to process natural facial somatosensory information and compare ...

journal_title：Journal of neurophysiology

authors： Schneider JS,Levine MS,Hull CD,Buchwald NA

更新日期：1985-07-01 00:00:00