Evidence for functionally distinct synaptic NMDA receptors in ventromedial versus dorsolateral striatum.

abstract：:Following stepping in-place on the surface of a rotating circular treadmill, a subject attempting to step in-place or walk in a straight line across the floor without vision will rotate relative to space. This adaptation, termed podokinetic after-rotation (PKAR), transfers to backward walking following forward walking...

journal_title：Journal of neurophysiology

authors： Earhart GM,Melvill Jones G,Horak FB,Block EW,Weber KD,Fletcher WA

更新日期：2002-02-01 00:00:00

abstract：:The superior colliculus (SC) provides signals for the generation of saccades via a direct pathway to the brain stem burst generator (BG). In addition, it sends saccade-related activity to the BG indirectly through the cerebellum via a relay in the nucleus reticularis tegmenti pontis (NRTP). Lesions of the oculomotor v...

journal_title：Journal of neurophysiology

authors： Kaneko CR,Fuchs AF

更新日期：2006-06-01 00:00:00

abstract：:Proinflammatory cytokines may sensitize primary sensory neurons and facilitate development of neuropathic pain processes after peripheral nerve injury. The goal of this study was to determine whether responses of dorsal root ganglion (DRG) neurons to exogenous tumor necrosis factor alpha (TNF-alpha) are altered in a c...

journal_title：Journal of neurophysiology

authors： Liu B,Li H,Brull SJ,Zhang JM

更新日期：2002-09-01 00:00:00

abstract：:Many laboratories have reported the successful regeneration of neurons across damaged portions of the spinal cord. Associated improvements in hindlimb locomotor movements have been attributed to the formation of functional neuronal connections with the locomotor central pattern generator (CPG). However, regenerating a...

journal_title：Journal of neurophysiology

authors： Yakovenko S,Kowalczewski J,Prochazka A

更新日期：2007-03-01 00:00:00

abstract：:Extracellular discharges from single neurons in the internal segment of the globus pallidus (GPi) were recorded and analyzed for rate changes associated with visually guided forearm rotations to four different targets. We sought to examine how GPi neurons contribute to movement preparation and execution. Unit discharg...

journal_title：Journal of neurophysiology

authors： Gdowski MJ,Miller LE,Parrish T,Nenonene EK,Houk JC

更新日期：2001-02-01 00:00:00

abstract：:In the rodent whisker system, a key model for neural processing and behavioral choices during active sensing, whisker motion is increasingly recognized as only part of a broader motor repertoire employed by rodents during active touch. In particular, recent studies suggest whisker and head motions are tightly coordina...

journal_title：Journal of neurophysiology

authors： Schroeder JB,Ritt JT

更新日期：2016-04-01 00:00:00

abstract：:Leopard frog saccular hair cells exhibit an electrical resonance in response to a depolarizing stimulus that has been proposed to contribute to the tuning properties of the frog sacculus by acting as an electrical band-pass filter. With the whole cell patch-clamp technique, we have investigated the effect of temperatu...

journal_title：Journal of neurophysiology

authors： Smotherman MS,Narins PM

更新日期：1998-01-01 00:00:00

abstract：:In rats, whisker trimming during development leads to persistent alterations in the function of cortical barrel circuits and to behavioral deficits later in life. Here we examined how whisker trimming begun either at birth (P0) or on postnatal day 12 (P12), around the onset of whisking behavior, affects receptive fiel...

journal_title：Journal of neurophysiology

authors： Shoykhet M,Land PW,Simons DJ

更新日期：2005-12-01 00:00:00

abstract：:This study of chronic incomplete spinal cord injury (SCI) subjects investigated patterns of central motor drive (i.e., central activation) of the plantar flexors using interpolated twitches, and modulation of soleus H-reflexes during lengthening, isometric, and shortening muscle actions. In a recent study of the knee ...

journal_title：Journal of neurophysiology

authors： Kim HE,Corcos DM,Hornby TG

更新日期：2015-07-01 00:00:00

abstract：:Synaptic plasticity in the amygdala is thought to underlie aversive or rewarding learning and emotional memories. In this study, different mechanisms were found to underlie synaptic plasticity in lateral (LA) and basolateral (BLA) amygdala pathways to the primary output nucleus of the amygdala, the central amygdala (C...

journal_title：Journal of neurophysiology

authors： Fu Y,Shinnick-Gallagher P

更新日期：2005-05-01 00:00:00

abstract：:We characterized the electroresponsive and morphological properties of neurons in the bed nucleus of the stria terminalis (BNST). Previously, Rainnie and colleagues distinguished three cell types in the anterolateral region of BNST (BNST-AL): low-threshold bursting cells (LTB; type II) and regular spiking neurons that...

journal_title：Journal of neurophysiology

authors： Rodríguez-Sierra OE,Turesson HK,Pare D

更新日期：2013-11-01 00:00:00

abstract：:With each eye movement, stationary objects in the world change position on the retina, yet we perceive the world as stable. Spatial updating, or remapping, is one neural mechanism by which the brain compensates for shifts in the retinal image caused by voluntary eye movements. Remapping of a visual representation is b...

journal_title：Journal of neurophysiology

authors： Merriam EP,Genovese CR,Colby CL

更新日期：2007-02-01 00:00:00

abstract：:Orexin-producing neurons are clearly essential for the regulation of wakefulness and sleep because loss of these cells produces narcolepsy. However, little is understood about how these neurons dynamically interact with other wake- and sleep-regulatory nuclei to control behavioral states. Using survival analysis of wa...

journal_title：Journal of neurophysiology

authors： Diniz Behn CG,Kopell N,Brown EN,Mochizuki T,Scammell TE

更新日期：2008-06-01 00:00:00

abstract：:In the first visual synapse of the insect compound eye, both the presynaptic and postsynaptic signals are graded, nonspiking changes in membrane voltage. The synapse exhibits tonic transmitter release (even in dark) and strong adaptation to long-lasting light backgrounds, leading to changes also in the dynamics of sig...

journal_title：Journal of neurophysiology

authors： Uusitalo RO,Weckström M

更新日期：2000-04-01 00:00:00

abstract：:A preparation is described in which the thoracic ganglia of the crayfish are isolated together with the thoracocoxal muscle receptor organ (TCMRO) of the fourth leg. This preparation allows intracellular analysis of both centrally generated and reflex activity in leg motor neurons (MNs). The isolated thoracic ganglia ...

journal_title：Journal of neurophysiology

authors： Sillar KT,Skorupski P

更新日期：1986-04-01 00:00:00

abstract：:A large array of neuroscientific techniques, including in vivo electrophysiology, two-photon imaging, optogenetics, lesions, and microdialysis, require access to the brain through the skull. Ideally, the necessary craniotomies could be performed in a repeatable and automated fashion, without damaging the underlying br...

journal_title：Journal of neurophysiology

authors： Pak N,Siegle JH,Kinney JP,Denman DJ,Blanche TJ,Boyden ES

更新日期：2015-06-01 00:00:00

abstract：:We recorded local field potentials (LFPs) and single-unit activity simultaneously in the macaque primary visual cortex (V1) and studied their responses to drifting sinusoidal gratings that were chosen to be "optimal" for the single units. Over all stimulus conditions, the LFP spectra have much greater power in the low...

journal_title：Journal of neurophysiology

authors： Henrie JA,Shapley R

更新日期：2005-07-01 00:00:00

abstract：:We investigated the afferents and intracortical synaptic organization of the anterior cingulate cortex (ACC) during noxious electrical stimulation. Extracellular field potentials were recorded simultaneously from 16 electrodes spanning all layers of the ACC in male Sprague-Dawley rats anesthetized by halothane inhalat...

journal_title：Journal of neurophysiology

authors： Yang JW,Shih HC,Shyu BC

更新日期：2006-12-01 00:00:00

abstract：:The topographical response of a portion of an isofrequency contour in primary cat auditory cortex (AI) to a series of monaural and binaural stimuli was studied. Responses of single neurons to monaural and a matrix of binaural characteristic frequency tones, varying in average binaural level (ABL) and interaural level ...

journal_title：Journal of neurophysiology

authors： Nakamoto KT,Zhang J,Kitzes LM

更新日期：2004-01-01 00:00:00

abstract：:Responses to tones, clicks, and noise were recorded from chinchilla auditory-nerve fibers (ANFs). The responses to noise were analyzed by computing the zeroth-, first-, and second-order Wiener kernels (h0, h1, and h2). The h1s correctly predicted the frequency tuning and phases of responses to tones of ANFs with low c...

journal_title：Journal of neurophysiology

authors： Temchin AN,Recio-Spinoso A,van Dijk P,Ruggero MA

更新日期：2005-06-01 00:00:00

abstract：:Foot drop is very common among people with chronic incomplete spinal cord injury (SCI) and likely stems from SCI that disturbs the corticospinal activation of the ankle dorsiflexor tibialis anterior (TA). Thus, if one can recover or increase the corticospinal excitability reduced by SCI, motor function recovery may be...

journal_title：Journal of neurophysiology

authors： Thompson AK,Fiorenza G,Smyth L,Favale B,Brangaccio J,Sniffen J

更新日期：2019-03-01 00:00:00

abstract：:Working memory (WM) performance is impaired by the presence of external interference. Accordingly, more efficient processing of intervening stimuli with practice may lead to enhanced WM performance. To explore the role of practice on the impact that interference has on WM performance, we studied young adults with elec...

journal_title：Journal of neurophysiology

authors： Berry AS,Zanto TP,Rutman AM,Clapp WC,Gazzaley A

更新日期：2009-09-01 00:00:00

abstract：:Motor-unit synchronization, which is a measure of the near simultaneous discharge of action potentials by motor units, has the potential to influence spike-triggered average force and the steadiness of a low-force isometric contraction. The purpose of the study was to estimate the contribution of motor-unit synchroniz...

journal_title：Journal of neurophysiology

authors： Semmler JG,Steege JW,Kornatz KW,Enoka RM

更新日期：2000-07-01 00:00:00

abstract：:Optogenetic activation of axons is a powerful approach for determining the synaptic properties and impact of long-range projections both in vivo and in vitro. However, because of the difficulty of measuring activity in axons, our knowledge of the reliability of optogenetic axonal stimulation has relied on data from so...

journal_title：Journal of neurophysiology

authors： Hass CA,Glickfeld LL

更新日期：2016-11-01 00:00:00

abstract：:1. The sensory responsiveness of cells in the inferior olive is known to be suppressed during certain phases of active movement. These experiments were designed to test the possibility that activity in the rubrospinal pathway contributes to this suppression. We recorded from cells sensitive to light touch located in o...

journal_title：Journal of neurophysiology

authors： Weiss C,Houk JC,Gibson AR

更新日期：1990-10-01 00:00:00

abstract：:We recorded single-unit activity of 25 units in the parafoveal representation of macaque V1 to transient appearance of sinusoidal gratings. Gratings were systematically varied in spatial phase and in one or two of the following: contrast, spatial frequency, and orientation. Individual responses were compared based on ...

journal_title：Journal of neurophysiology

authors： Victor JD,Purpura KP

更新日期：1998-08-01 00:00:00

abstract：:Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rat...

journal_title：Journal of neurophysiology

authors： Moorman DE,Olson CR

更新日期：2007-05-01 00:00:00

abstract：:1. Monkeys with large unilateral surgical ablations of striate cortex, sustained either in adulthood or at 5-6 wk of age, were trained on an oculomotor detection and localization task and tested with visual stimuli in the hemifields ipsilateral and contralateral to the lesion 2-5 yr after surgery. 2. Monkeys with lesi...

journal_title：Journal of neurophysiology

authors： Moore T,Rodman HR,Repp AB,Gross CG,Mezrich RS

更新日期：1996-12-01 00:00:00

abstract：:It is well established that neural networks respond to a wide variety of modulatory substances by which they can become reconfigured, yet few studies have examined the effects of neurotransmitter mixtures on such networks. In a previous study of the medicinal leech using triple intracellular recordings, we found that ...

journal_title：Journal of neurophysiology

authors： Mesce KA,Crisp KM,Gilchrist LS

更新日期：2001-05-01 00:00:00

abstract：:In rat CA1 hippocampal pyramidal neurons (HPNs), somatostatin (SST) has inhibitory postsynaptic actions, including hyperpolarization of the membrane at rest and augmentation of the K+ M-current. However, the effects of SST on synaptic transmission in this brain region have not been well-characterized. Therefore we use...

journal_title：Journal of neurophysiology

authors： Tallent MK,Siggins GR

更新日期：1997-12-01 00:00:00