Motor-unit synchronization is not responsible for larger motor-unit forces in old adults.

abstract：:Although frequency-dependent short-term presynaptic plasticity has been of long-standing interest, most studies have emphasized modulation of the synchronous, phasic component of transmitter release, most evident with a single or a few presynaptic stimuli. Asynchronous transmitter release, vesicle fusion not closely t...

journal_title：Journal of neurophysiology

authors： Chang CY,Mennerick S

更新日期：2010-01-01 00:00:00

abstract：:How does the motor system choose the speed for any given movement? Many current models assume a process that finds the optimal balance between the costs of moving fast and the rewards of achieving the goal. Here, we show that such models also need to take into account a prior representation of preferred movement speed...

journal_title：Journal of neurophysiology

authors： Hammerbeck U,Yousif N,Greenwood R,Rothwell JC,Diedrichsen J

更新日期：2014-01-01 00:00:00

abstract：:1. High-threshold Ca2+ currents were studied in large pyramidal cells acutely dissociated from the rat amygdaloid complex. L-, N-, and P-type currents were present in about equal proportions in these cells and accounted for most of the whole-cell current. ...

journal_title：Journal of neurophysiology

authors： Foehring RC,Scroggs RS

更新日期：1994-01-01 00:00:00

abstract：:Dopaminergic modulation produces a variety of functional changes in the principal cell of the striatum, the medium spiny neuron (MSN). Using a 189-compartment computational model of a ventral striatal MSN, we simulated whole cell D1- and D2-receptor-mediated modulation of both intrinsic (sodium, calcium, and potassium...

journal_title：Journal of neurophysiology

authors： Moyer JT,Wolf JA,Finkel LH

更新日期：2007-12-01 00:00:00

abstract：:We have shown previously that in the acutely spinalized anesthetized rat the activities of many dorsal horn interneurons (DHN) at the T(10) level are correlated positively with both ongoing and stimulus-evoked renal sympathetic nerve activity (RSNA) and therefore may belong to networks generating RSNA after acute, cer...

journal_title：Journal of neurophysiology

authors： Chau D,Johns DG,Schramm LP

更新日期：2000-05-01 00:00:00

abstract：:Changes to cerebral miRNA expression have been implicated in the progression of Alzheimer's disease (AD), as miRNAs that regulate the expression of gene products involved in amyloid beta (Aβ) processing, such as BACE1, are dysregulated in those that suffer from AD. Exercise training improves cognition and reduces BACE...

journal_title：Journal of neurophysiology

authors： Dungan CM,Valentino T,Vechetti IJ Jr,Zdunek CJ,Murphy MP,Lin AL,McCarthy JJ,Peterson CA

更新日期：2020-12-01 00:00:00

abstract：:Most studies investigating neural representations of species-specific vocalizations in non-human primates and other species have involved studying neural responses to vocalization tokens. One limitation of such approaches is the difficulty in determining which acoustical features of vocalizations evoke neural response...

journal_title：Journal of neurophysiology

authors： DiMattina C,Wang X

更新日期：2006-02-01 00:00:00

abstract：:Endocannabinoids released from the postsynaptic neuronal membrane can activate presynaptic CB1 receptors and inhibit neurotransmitter release. In hippocampal slices, depolarization of the CA1 pyramidal neurons elicits an endocannabinoid-mediated inhibition of gamma-aminobutyric acid release known as depolarization-ind...

journal_title：Journal of neurophysiology

authors： Sheinin A,Talani G,Davis MI,Lovinger DM

更新日期：2008-08-01 00:00:00

abstract：:1. Biventer cervicis (BC) is an anatomically complex muscle that is divided by tendinous inscriptions into five in-series compartments of motor units. We have analyzed the fiber architecture and fiber-type composition of these different compartments using microdissection and histochemical methods. 2. BC narrows as it ...

journal_title：Journal of neurophysiology

authors： Richmond FJ,Armstrong JB

更新日期：1988-07-01 00:00:00

abstract：:Responses have been recorded from primary endings of muscle spindles in the cat soleus muscle. Changes in spindle responsiveness were measured following a period of conditioning that consisted of a series of rapid stretches or of tetanic ventral root stimulation. In the testing procedure the response of a single spind...

journal_title：Journal of neurophysiology

authors： Gregory JE,Morgan DL,Proske U

更新日期：1986-08-01 00:00:00

abstract：:1. A quantal analysis of transmission at the identified molluscan synapse, V2-RPr1, was performed during development. The study was intended to determine the pre- and postsynaptic contributions to the marked changes in transmitter release described in the previous report. 2. The success of the quantal analysis was pre...

journal_title：Journal of neurophysiology

authors： Pawson PA,Chase R

更新日期：1988-12-01 00:00:00

abstract：:An important new study by Kvarta, Bradbrook, Dantrassy, Bailey, and Thompson (J Neurophysiol 114: 1713-1724, 2015) examined the effects of persistent stress and excessive glucocorticoid levels on hippocampal function and emotional behavior in rodents. The authors specifically implicate the temporoammonic pathway as be...

journal_title：Journal of neurophysiology

authors： McGinn MA,Pahng AR

更新日期：2017-02-01 00:00:00

abstract：:To investigate the nature of the visuomotor transformation, previous studies have used pointing tasks and examined how adaptation to a spatially localized mismatch between vision and proprioception generalizes across the workspace. Whereas some studies found extensive spatial generalization of single-point remapping, ...

journal_title：Journal of neurophysiology

authors： Malfait N,Henriques DY,Gribble PL

更新日期：2008-01-01 00:00:00

abstract：:Such perisaccadic mislocalization is maximal in the direction of the saccade and varies systematically with the target-saccade onset delay. We have recently shown that under head-fixed conditions perisaccadic errors do not follow the quantitative predictions of current visuomotor models that explain these mislocalizat...

journal_title：Journal of neurophysiology

authors： van Wetter SM,van Opstal AJ

更新日期：2008-10-01 00:00:00

abstract：:Primary afferent fibers from the electroreceptors of mormyrid electric fish use a latency code to signal the intensity of electrical current evoked by the fish's own electric organ discharge (EOD). The afferent fibers terminate centrally in the deep and superficial granular layers of the electrosensory lobe with morph...

journal_title：Journal of neurophysiology

authors： Zhang J,Han VZ,Meek J,Bell CC

更新日期：2007-03-01 00:00:00

abstract：:The centre médian-parafascicular (CM-Pf) complex is located at the posterior intralaminar nuclei of the thalamus and forms part of the nonspecific thalamocortical projection system and the internal circuit of the basal ganglia. However, the functional roles of this complex remain to be fully elucidated. Here we have e...

journal_title：Journal of neurophysiology

authors： Minamimoto T,Kimura M

更新日期：2002-06-01 00:00:00

abstract：:For human locomotion, varying environments require adjustments of the motor system. We asked whether age affects gait balance recovery adaptation, its retention over months, and the transfer of adaptation to an untrained reactive balance task. Healthy adults (26 young, 27 middle-aged, and 25 older; average ages 24, 52...

journal_title：Journal of neurophysiology

authors： König M,Epro G,Seeley J,Potthast W,Karamanidis K

更新日期：2019-11-01 00:00:00

abstract：:Many electrophysiologists view neurotransmitter transporters as tiny vacuum cleaners, operating continuously to lower extracellular neurotransmitter concentration to zero. However, this is not consistent with their known behavior, instead only reducing extracellular neurotransmitter concentration to a finite, nonzero ...

journal_title：Journal of neurophysiology

authors： Richerson GB,Wu Y

更新日期：2003-09-01 00:00:00

abstract：:ALS (amyotrophic lateral sclerosis) is an adult-onset and deadly neurodegenerative disease characterized by a progressive and selective loss of motoneurons. Transgenic mice overexpressing a mutated human gene (G93A) coding for the enzyme SOD1 (Cu/Zn superoxide dismutase) develop a motoneuron disease resembling ALS in ...

journal_title：Journal of neurophysiology

authors： Kuo JJ,Schonewille M,Siddique T,Schults AN,Fu R,Bär PR,Anelli R,Heckman CJ,Kroese AB

更新日期：2004-01-01 00:00:00

abstract：:1. In the European rock lobster, Homarus gammarus, two bilaterally symmetrical pairs of commissural neurons, P and commissural pyloric (CP), evoke excitatory postsynaptic potentials in the neurons of the pyloric motor network. The present paper shows that the two commissural neurons also exert a modulatory control ove...

journal_title：Journal of neurophysiology

authors： Nagy F,Cardi P

更新日期：1994-06-01 00:00:00

abstract：:1. Using patch-clamp methods, we show that brief prepulses to very positive voltages increase (facilitate) the amplitude of current through Ca2+ channels during a subsequent test pulse in some, but not all, dorsal root ganglion (DRG) sensory neurons. The amplitude of this facilitated current generally increases when t...

journal_title：Journal of neurophysiology

authors： Womack MD,McCleskey EW

更新日期：1995-05-01 00:00:00

abstract：:We characterized the electroresponsive and morphological properties of neurons in the bed nucleus of the stria terminalis (BNST). Previously, Rainnie and colleagues distinguished three cell types in the anterolateral region of BNST (BNST-AL): low-threshold bursting cells (LTB; type II) and regular spiking neurons that...

journal_title：Journal of neurophysiology

authors： Rodríguez-Sierra OE,Turesson HK,Pare D

更新日期：2013-11-01 00:00:00

abstract：:1. The proton-gated current was investigated in whole-cell configuration of the neurons isolated from bullfrog heart parasympathetic ganglia with the use of the "concentration-clamp" technique, which combines intracellular perfusion and extremely rapid exchange of external solution within 1-2 ms, under a single-electr...

journal_title：Journal of neurophysiology

authors： Kim DK,Tateishi N,Akaike N

更新日期：1990-05-01 00:00:00

abstract：:Proinflammatory cytokines may sensitize primary sensory neurons and facilitate development of neuropathic pain processes after peripheral nerve injury. The goal of this study was to determine whether responses of dorsal root ganglion (DRG) neurons to exogenous tumor necrosis factor alpha (TNF-alpha) are altered in a c...

journal_title：Journal of neurophysiology

authors： Liu B,Li H,Brull SJ,Zhang JM

更新日期：2002-09-01 00:00:00

abstract：:The primate posterior thalamus has been proposed to contribute to pain sensation, but its precise role is unclear. This is in part because spinothalamic tract (STT) neurons that project to the posterior thalamus have received little attention. In this study, antidromic mapping was used to identify individual STT neuro...

journal_title：Journal of neurophysiology

authors： Davidson S,Zhang X,Khasabov SG,Simone DA,Giesler GJ Jr

更新日期：2008-10-01 00:00:00

abstract：:1. The modulation of the voltage-activated Ca2+ current by the neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFa) was investigated in dissociated central neurons from Helix aspersa using whole-cell voltage-clamp recording techniques. External Ba2+ was always used as the charge carrier in this study, and the intracellular Ca2+ c...

journal_title：Journal of neurophysiology

authors： Yakel JL

更新日期：1991-06-01 00:00:00

abstract：:We have demonstrated that 4-aminopyridine-3-methanol (4-AP-3-MeOH), a 4-aminopyridine derivative, significantly restores axonal conduction in stretched spinal cord white-matter strips and shows no preference in restoring large and small axons. This compound is 10 times more potent when compared with 4-AP and other der...

journal_title：Journal of neurophysiology

authors： Sun W,Smith D,Fu Y,Cheng JX,Bryn S,Borgens R,Shi R

更新日期：2010-01-01 00:00:00

abstract：:Male zebra finches produce a song consisting of a canonical sequence of syllables, learned from a tutor and repeated throughout its adult life. Much of the neural circuitry responsible for this behavior is located in the cortical premotor region HVC (acronym is name). In a recent study from our laboratory, we found th...

journal_title：Journal of neurophysiology

authors： Galvis D,Wu W,Hyson RL,Johnson F,Bertram R

更新日期：2017-08-01 00:00:00

abstract：:The macaque middle temporal area (MT) is exquisitely sensitive to visual motion and there is a large amount of evidence that neural activity in MT is tightly correlated with the perception of motion. The mechanisms by which MT neurons achieve their directional selectivity, however, have received considerably less atte...

journal_title：Journal of neurophysiology

authors： Krekelberg B,Albright TD

更新日期：2005-05-01 00:00:00

abstract：:1. Plasticity at the connections between sensory neurons and their follower cells in Aplysia has been used extensively as a model system to examine mechanisms of simple forms of learning. Earlier studies have concluded that serotonin (5-HT) is a key modulatory transmitter and that it exerts its short-term actions via ...

journal_title：Journal of neurophysiology

authors： Sugita S,Goldsmith JR,Baxter DA,Byrne JH

更新日期：1992-08-01 00:00:00