Effects of dopaminergic modulation on the integrative properties of the ventral striatal medium spiny neuron.

abstract：:The earliest neural response to a mechanical perturbation, the short-latency stretch response (R1: 20-45 ms), is known to exhibit "automatic gain-scaling" whereby its magnitude is proportional to preperturbation muscle activity. Because gain-scaling likely reflects an intrinsic property of the motoneuron pool (via the...

journal_title：Journal of neurophysiology

authors： Pruszynski JA,Kurtzer I,Lillicrap TP,Scott SH

更新日期：2009-08-01 00:00:00

abstract：:Cats were reared in total darkness from birth until 4-5 mo of age (DR cats, n = 7) or with very brief visual experience (1 or 2 days) during an otherwise similar period of dark rearing [DR(1) cats, n = 3; DR(2) cats, n = 7]. Single-cell recordings were made in area 17 of visual cortex at the end of this rearing period...

journal_title：Journal of neurophysiology

authors： Mower GD,Christen WG

更新日期：1985-02-01 00:00:00

abstract：:Synaptic currents are frequently assumed to make a major contribution to the extracellular field potential (EFP). However, in any neuronal population, the explicit separation of synaptic sources from other contributions such as postsynaptic spikes remains a challenge. Here we take advantage of the simple organization ...

journal_title：Journal of neurophysiology

authors： McColgan T,Kuokkanen PT,Carr CE,Kempter R

更新日期：2019-03-01 00:00:00

abstract：:The functional role of sensory input to the motor cortex was studied by interrupting two major input pathways. One was the dorsal column, which sends the input directly through the thalamus to the motor cortex, and the other was the sensory cortex, which transfers its input through association fibers. Removal of the s...

journal_title：Journal of neurophysiology

authors： Asanuma H,Arissian K

更新日期：1984-08-01 00:00:00

abstract：:1. Evidence for local excitatory synaptic connections in CA1 of the rat hippocampus was obtained by recording excitatory postsynaptic potentials (EPSPs) intracellularly from pyramidal cells during local microapplications of glutamate. 2. Experiments were performed in hippocampal slices cut parallel to (transverse slic...

journal_title：Journal of neurophysiology

authors： Christian EP,Dudek FE

更新日期：1988-01-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:Augmenting (or incremental) responses are progressively growing potentials elicited by 5- to 15-Hz stimulation within the thalamus, cerebral cortex, or by setting into action reciprocal thalamocortical neuronal loops. These responses are associated with short-term plasticity processes in thalamic and cortical neurons....

journal_title：Journal of neurophysiology

authors： Timofeev I,Steriade M

更新日期：1998-05-01 00:00:00

abstract：:1. In cultured rat locus coeruleus neurons, somatostatin or met-enkephalin induces an inwardly rectifying K+ conductance. This inward rectifier was analyzed at the single-channel level. 2. Using the inside-out patch-clamp, guanosine 5'-triphosphate (GTP) application to the cytoplasmic side in the presence of somatosta...

journal_title：Journal of neurophysiology

authors： Grigg JJ,Kozasa T,Nakajima Y,Nakajima S

更新日期：1996-01-01 00:00:00

abstract：:Effective connectivity between cortical areas decreases during slow wave sleep. This decline can be observed in the reduced interareal propagation of activity evoked either directly in cortex by transcranial magnetic stimulation (TMS) or by sensory stimulation. We present here a large-scale model of the thalamocortica...

journal_title：Journal of neurophysiology

authors： Esser SK,Hill S,Tononi G

更新日期：2009-10-01 00:00:00

abstract：:Previous studies of visual processing in humans using event-related potentials (ERPs) have demonstrated that task-related modulations of an early component called the "N1" wave (140-200 ms) reflect the operation of a voluntary discrimination process. Specifically, this component is larger in tasks requiring target dis...

journal_title：Journal of neurophysiology

authors： Hopf JM,Vogel E,Woodman G,Heinze HJ,Luck SJ

更新日期：2002-10-01 00:00:00

abstract：:1. Using floating electrodes, we recorded from neck-muscle spindle afferents in the C2 dorsal root ganglion of the decerebrate cat. Nerves to dorsal neck muscles were cut so that the afferents presumably originated mainly from ventral and ventrolateral perivertebral muscles and sternocleidomastoid. One goal of our exp...

journal_title：Journal of neurophysiology

authors： Kasper J,Wilson VJ,Yamagata Y,Yates BJ

更新日期：1989-10-01 00:00:00

abstract：:Cortical pyramidal cells are constantly bombarded by synaptic activity, much of which arises from other cortical neurons, both in normal conditions and during epileptic seizures. The action potentials generated by barrages of synaptic activity may exhibit a variable site of origin. Here we performed simultaneous whole...

journal_title：Journal of neurophysiology

authors： Shu Y,Duque A,Yu Y,Haider B,McCormick DA

更新日期：2007-01-01 00:00:00

abstract：:Moth pheromones cause rises in intracellular Ca(2+) concentrations that activate Ca(2+)-dependent cation channels in antennal olfactory receptor neurons. In addition, mechanisms of adaptation and sensitization depend on changes in cyclic nucleotide concentrations. Here, cyclic nucleotide-activated currents in cultured...

journal_title：Journal of neurophysiology

authors： Krannich S,Stengl M

更新日期：2008-11-01 00:00:00

abstract：:Our goal was to understand how patterns of excitation and inhibition, interacting across arrays of ganglion cells in space and time, generate the spiking output pattern for each ganglion cell type. We presented the retina with a 1-s flashed square, 600 microm on a side, and measured patterns of excitation and inhibiti...

journal_title：Journal of neurophysiology

authors： Roska B,Molnar A,Werblin FS

更新日期：2006-06-01 00:00:00

abstract：:Arrays of closely spaced quartz-insulated, platinum-tungsten microelectrodes are widely used to obtain acute recordings from chronically prepared subjects. These electrodes have excellent recording characteristics and can be fabricated to a wide variety of tip specifications. Typically, in such experiments, electrodes...

journal_title：Journal of neurophysiology

authors： Swadlow HA,Bereshpolova Y,Bezdudnaya T,Cano M,Stoelzel CR

更新日期：2005-05-01 00:00:00

abstract：:1. Somatic K currents of cultured hippocampal, striatal, and spinal cord neurons of embryonic rat were recorded under voltage clamp in membrane spheres ("blebs") excised by means of a tight-seal pipette. 2. The somatic K current in blebs was subject to rapid and near complete inactivation during 300-ms depolarizations...

journal_title：Journal of neurophysiology

authors： Rizzo MA,Nonner W

更新日期：1992-11-01 00:00:00

abstract：:In sensory systems, the thalamus has historically been considered a relay station. Neural representations of temporal modulations in the auditory system undergo considerable changes as they pass from the inferior colliculus (IC) to the auditory cortex. We sought to determine in awake primates the extent to which audit...

journal_title：Journal of neurophysiology

authors： Bartlett EL,Wang X

更新日期：2007-02-01 00:00:00

abstract：:The problem of how the hippocampus encodes both spatial and nonspatial information at the cellular network level remains largely unresolved. Spatial memory is widely modeled through the theoretical framework of attractor networks, but standard computational models can only represent spaces that are much smaller than t...

journal_title：Journal of neurophysiology

authors： Hedrick KR,Zhang K

更新日期：2016-08-01 00:00:00

abstract：:The brain can precisely encode the temporal relationship between tactile inputs. While behavioural studies have demonstrated precise interfinger temporal judgments, the underlying neural mechanism remains unknown. Computationally, two kinds of neural responses can act as the information source. One is the phase-locked...

journal_title：Journal of neurophysiology

authors： Kuroki S,Watanabe J,Nishida S

更新日期：2016-03-01 00:00:00

abstract：:In contrast to hand movements, the existence of a neural representation of saccade kinematics is unclear. Saccade kinematics is typically thought to be specified by motor error/desired displacement and generated by brain stem circuits that are not penetrable to voluntary control. We studied the influence of instructed...

journal_title：Journal of neurophysiology

authors： Gopal A,Jana S,Murthy A

更新日期：2017-09-01 00:00:00

abstract：:1. Large, projection-like neurons from the adult (> 3 wk post-natal) rat globus pallidus (GP) were acutely isolated and subjected to whole-cell voltage-clamp (n = 37). Ca2+ currents were isolated pharmacologically in cells with whole-cell capacitances of 15-34 pF. 2. With 5 mM Ba2+ as a charge carrier, whole-cell curr...

journal_title：Journal of neurophysiology

authors： Surmeier DJ,Seno N,Kitai ST

更新日期：1994-03-01 00:00:00

abstract：:The properties of the vestibuloocular reflex (VOR) when the axis of rotation is behind the eyes and fixation of a near target is required were studied in the monkey. The magnitude of VOR gain in each eye was found to be above 1.0 and near the ideal value for stabilizing a retinal image. Evidence that this large VOR ga...

journal_title：Journal of neurophysiology

authors： Viirre E,Tweed D,Milner K,Vilis T

更新日期：1986-08-01 00:00:00

abstract：:The basal ganglia participate in motor functions and are implicated in the pathophysiology of movement disorders. It has been shown in primates that the activity of many neurons in one of the basal ganglia output nuclei, the internal segment of the globus pallidus, changes with active or passive movements. The involve...

journal_title：Journal of neurophysiology

authors： Wichmann T,Kliem MA

更新日期：2004-02-01 00:00:00

abstract：:In vitro whole cell patch-clamp recordings of stellate cells in layer II of medial entorhinal cortex show a subthreshold membrane potential resonance in response to a sinusoidal current injection of varying frequency. Physiological recordings from awake behaving animals show that neurons in layer II medial entorhinal ...

journal_title：Journal of neurophysiology

authors： Heys JG,Giocomo LM,Hasselmo ME

更新日期：2010-07-01 00:00:00

abstract：:Transcranial magnetic stimulation (TMS) is increasingly used to modify brain activity noninvasively and to study brain-behavior relations. However, results can be variable and the conditions that affect the functional efficacy of TMS remain unclear. Here we show that on-line TMS can either facilitate or suppress perce...

journal_title：Journal of neurophysiology

authors： Silvanto J,Cattaneo Z,Battelli L,Pascual-Leone A

更新日期：2008-05-01 00:00:00

abstract：:Extracellular recordings of 209 neurons were obtained with carbon fiber-containing multibarrel micropipettes. The cells were isolated in the primary somatosensory cortex of cats anesthetized with barbiturate and classified according to the nature of their response to natural stimuli, the nature of the surrounding mult...

journal_title：Journal of neurophysiology

authors： Dykes RW,Landry P,Metherate R,Hicks TP

更新日期：1984-12-01 00:00:00

abstract：:Microsleeps are brief episodes of arousal level decrease manifested through behavioral signs. Brain activity during microsleep in the presence of external stimulus remains poorly understood. In this study, we sought to understand neural responses to auditory stimulation during microsleep. We gave participants the simp...

journal_title：Journal of neurophysiology

authors： Yong Z,Tan JH,Hsieh PJ

更新日期：2019-12-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:Contusion-type injuries to the spinal cord are characterized by tissue loss and disruption of spinal pathways. Midcervical spinal cord injuries impair the function of respiratory muscles and may contribute to significant respiratory complications. This study systematically assessed the impact of a 100-kDy unilateral C...

journal_title：Journal of neurophysiology

authors： Rana S,Sieck GC,Mantilla CB

更新日期：2017-02-01 00:00:00

abstract：:1. The extracellular activity of 45 antidromically identified spinocervical tract (SCT) neurons responsive to light mechanical stimulation of the glabrous surfaces of the forepaw was examined in raccoons anesthetized with pentobarbital sodium. An additional seven neurons had peripheral receptive fields (RFs) located o...

journal_title：Journal of neurophysiology

authors： Hirata H,Pubols BH Jr

更新日期：1989-01-01 00:00:00