Localizing visual discrimination processes in time and space.

abstract：:Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

journal_title：Journal of neurophysiology

authors： Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

更新日期：2012-05-01 00:00:00

abstract：:The ventroposterior region of the thalamus of mongrel cats was searched to locate zones activated by somatic stimuli. By using stimuli that selectively excited Pacinian corpuscles, areas activated by this class of afferent fibers were differentiated from regions activated by other classes of cutaneous mechanoreceptors...

journal_title：Journal of neurophysiology

authors： Herron P,Dykes R

更新日期：1986-12-01 00:00:00

abstract：:The McGurk illusion is a prominent example of audiovisual speech perception and the influence that visual stimuli can have on auditory perception. In this illusion, a visual speech stimulus influences the perception of an incongruent auditory stimulus, resulting in a fused novel percept. In this high-density electroen...

journal_title：Journal of neurophysiology

authors： Roa Romero Y,Senkowski D,Keil J

更新日期：2015-04-01 00:00:00

abstract：:Microglia constitute ~10-20% of glial cells in the adult human brain. They are the resident phagocytic immune cells of the central nervous system and play an integral role as first responders during inflammation. Microglia are commonly classified as "HM" (homeostatic), "M1" (classically activated proinflammatory), or ...

journal_title：Journal of neurophysiology

authors： von Maydell D,Jorfi M

更新日期：2019-10-01 00:00:00

abstract：:1. We studied adenosine's action on synaptic transmission from primary afferent fibers to neurons of the substantia gelatinosa (SG) using tight-seal whole cell recordings in transverse slices of hamster spinal cord. Adenosine had two actions, hyperpolarization of the postsynaptic membrane and depression of the excitat...

journal_title：Journal of neurophysiology

authors： Li J,Perl ER

更新日期：1994-10-01 00:00:00

abstract：:We investigated spike-frequency adaptation of neurons sensitive to interaural phase disparities (IPDs) in the inferior colliculus (IC) of urethane-anesthetized guinea pigs using a stimulus paradigm designed to exclude the influence of adaptation below the level of binaural integration. The IPD-step stimulus consists o...

journal_title：Journal of neurophysiology

authors： Ingham NJ,McAlpine D

更新日期：2004-02-01 00:00:00

abstract：:Neurons of the avian nucleus laminaris (NL) compute the interaural time difference (ITD) by detecting coincident arrivals of binaural signals with submillisecond accuracy. The cellular mechanisms for this temporal precision have long been studied theoretically and experimentally. The myelinated axon initial segment in...

journal_title：Journal of neurophysiology

authors： Ashida G,Abe K,Funabiki K,Konishi M

更新日期：2007-03-01 00:00:00

abstract：:The study of quadrupeds has furnished most of our understanding of mammalian locomotion. To allow a more direct comparison of coordination between the four limbs in humans and quadrupeds, we studied crawling in the human, a behavior that is part of normal human development and mechanically more similar to quadrupedal ...

journal_title：Journal of neurophysiology

authors： Patrick SK,Noah JA,Yang JF

更新日期：2009-02-01 00:00:00

abstract：:1. In cultured rat locus coeruleus neurons, somatostatin or met-enkephalin induces an inwardly rectifying K+ conductance. This inward rectifier was analyzed at the single-channel level. 2. Using the inside-out patch-clamp, guanosine 5'-triphosphate (GTP) application to the cytoplasmic side in the presence of somatosta...

journal_title：Journal of neurophysiology

authors： Grigg JJ,Kozasa T,Nakajima Y,Nakajima S

更新日期：1996-01-01 00:00:00

abstract：:1. The effects of dorsal raphe (DR) stimulation on neural activity in the rat lateral hypothalamic area (LHA), including specific glucose-sensitive neurons, were investigated by extracellular and intracellular recording in vivo, and the neurotransmitters involved were determined. 2. In 67 adult male anesthetized rats,...

journal_title：Journal of neurophysiology

authors： Kai Y,Oomura Y,Shimizu N

更新日期：1988-08-01 00:00:00

abstract：:Pyramidal cells in the dorsal cochlear nucleus (DCN) show three characteristic discharge patterns in response tones: pauser, buildup, and regular firing. Experimental evidence suggests that a rapidly inactivating K+ current (I(KIF)) plays a critical role in generating these discharge patterns. To explore the role of I...

journal_title：Journal of neurophysiology

authors： Kanold PO,Manis PB

更新日期：2001-02-01 00:00:00

abstract：:L-type calcium channels couple membrane depolarization in neurons to numerous processes including gene expression, synaptic efficacy, and cell survival. To establish the contribution of L-type calcium channels to various signaling cascades, investigators have relied on their unique pharmacological sensitivity to dihyd...

journal_title：Journal of neurophysiology

authors： Lipscombe D,Helton TD,Xu W

更新日期：2004-11-01 00:00:00

abstract：:People naturally direct their gaze to visible hand movement goals. Doing so improves reach accuracy through use of signals related to gaze position and visual feedback of the hand. Here, we studied where people naturally look when acting on remembered target locations. Four targets were presented on a screen, in perip...

journal_title：Journal of neurophysiology

authors： Flanagan JR,Terao Y,Johansson RS

更新日期：2008-09-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:Mechanisms of direction selectivity and speed selectivity were studied in single neurons of the middle temporal visual area (MT) of behaving macaque monkeys. Visual stimuli were presented in both smooth and stroboscopic motion within a neuron's receptive field as the monkey fixated a stationary point of light. Directi...

journal_title：Journal of neurophysiology

authors： Mikami A,Newsome WT,Wurtz RH

更新日期：1986-06-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00

abstract：:The functional maturation of cuneate neurons was studied using reproducible tactile stimulation procedures and quantitative assessment of coding capacities in anesthetized (N2O/O2 plus barbiturate infusion) or decerebrate cats from six different age groups; neonatal (1-5 days), 10-15, 25-30, 55-63, and 83-90 days, and...

journal_title：Journal of neurophysiology

authors： Connor KM,Ferrington DG,Rowe MJ

更新日期：1984-07-01 00:00:00

abstract：:1. The question of whether active uptake limits the duration of action of the inhibitory transmitter glycine has been addressed in vivo at inhibitory synapses on the goldfish Mauthner (M) cell. The kinetics of inhibitory postsynaptic potentials and inhibitory postsynaptic currents (IPSCs) evoked antidromically and by ...

journal_title：Journal of neurophysiology

authors： Titmus MJ,Korn H,Faber DS

更新日期：1996-04-01 00:00:00

abstract：:To elucidate how information is processed in the vestibuloocular reflex (VOR) pathways subserving vertical eye movements, extracellular single-unit recordings were obtained from the vestibular nuclei of alert monkeys trained to track a visual target with their eyes while undergoing sinusoidal pitch oscillations (0.2-1...

journal_title：Journal of neurophysiology

authors： Chubb MC,Fuchs AF,Scudder CA

更新日期：1984-10-01 00:00:00

abstract：:N-Acetylaspartylglutamate (NAAG) is an agonist at the type 3 metabotropic glutamate receptor (mGluR3), which is coupled to a Gi/o protein. When activated, the mGluR3 receptor inhibits adenylyl cyclase and reduces the cAMP-mediated second-messenger cascade. Long-term potentiation (LTP) in the medial perforant path (MPP...

journal_title：Journal of neurophysiology

authors： Lea PM 4th,Wroblewska B,Sarvey JM,Neale JH

更新日期：2001-03-01 00:00:00

abstract：:1. Patterns of respiratory neuronal activity were examined in pentobarbitone anesthetized adult cats in a circumscribed area of the ventrolateral medulla, which has previously been defined as the pre-Bötzinger complex (pre-BOTC) from electrophysiological and morphological criteria in the brain stem-spinal cord prepara...

journal_title：Journal of neurophysiology

authors： Schwarzacher SW,Smith JC,Richter DW

更新日期：1995-04-01 00:00:00

abstract：:High-frequency oscillatory activity (>200 Hz) termed "fast oscillations" (FO) have been recorded in the rodent somatosensory cortex and may reflect very rapid integration of vibrissal information in sensory cortex. Yet, while electrophysiological correlates suggest that FO is generated within intracortical networks, c...

journal_title：Journal of neurophysiology

authors： Staba RJ,Brett-Green B,Paulsen M,Barth DS

更新日期：2003-05-01 00:00:00

abstract：:Animal survival in the forest, and human success on the sports field, often depend on the ability to seize a target on the fly. All bodies fall at the same rate in the gravitational field, but the corresponding retinal motion varies with apparent viewing distance. How then does the brain predict time-to-collision unde...

journal_title：Journal of neurophysiology

authors： Miller WL,Maffei V,Bosco G,Iosa M,Zago M,Macaluso E,Lacquaniti F

更新日期：2008-04-01 00:00:00

abstract：:The inferior colliculus (IC) is highly modulated by descending projections from higher auditory and nonauditory centers. Traditionally, corticofugal fibers were believed to project mainly to the extralemniscal IC regions. However, there is some anatomical evidence suggesting that a substantial number of fibers from th...

journal_title：Journal of neurophysiology

authors： Lim HH,Anderson DJ

更新日期：2007-02-01 00:00:00

abstract：:The cholinergic system is critically involved in synaptic models of learning and memory by enhancing dendritic [Ca(2+)](i) signals. Diffuse cholinergic innervation suggests subcellular modulation of membrane currents and Ca(2+) signals. Here we use ion-selective microelectrodes to study spread of carbachol (CCh) after...

journal_title：Journal of neurophysiology

authors： Egorov AV,Gloveli T,Müller W

更新日期：1999-10-01 00:00:00

abstract：:1. Extracellular bath application of the selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor KN-62 to hippocampal slices in vitro blocked the induction of long-term depression (LTD) by low-frequency Schaffer collateral stimulation (1 Hz/15 min) of the same concentration as has been shown previously to pre...

journal_title：Journal of neurophysiology

authors： Stanton PK,Gage AT

更新日期：1996-09-01 00:00:00

abstract：:The rostral ventromedial medulla (RVM) modulates nociception through changes in the activity of two classes of neuron, ON- and OFF-cells. The activity of these neurons is regulated, in part, by input from the periaqueductal gray (PAG). The objective of this study was to determine whether PAG-mediated antinociception i...

journal_title：Journal of neurophysiology

authors： Tortorici V,Morgan MM

更新日期：2002-10-01 00:00:00

abstract：:A series of studies were carried out to investigate the role of the cerebellar flocculus and ventral paraflocculus in the ability to voluntarily cancel the vestibuloocular reflex (VOR). Squirrel monkeys were trained to pursue moving visual targets and to fixate a head stationary or earth stationary target during passi...

journal_title：Journal of neurophysiology

authors： Belton T,McCrea RA

更新日期：2000-09-01 00:00:00

abstract：:1. In a brain stem slice preparation, we recorded glutamatergic excitatory postsynaptic currents (EPSCs) in hypoglossal motoneurons (HMs) evoked by extracellular stimulation in the reticular formation just ipsilateral to the hypoglossal motor nucleus (n. XII). Serotonin (5-HT) inhibited glutamatergic synaptic transmis...

journal_title：Journal of neurophysiology

authors： Singer JH,Bellingham MC,Berger AJ

更新日期：1996-08-01 00:00:00