A physiologically based model of discharge pattern regulation by transient K+ currents in cochlear nucleus pyramidal cells.

abstract：:We studied adjustments in digit forces and moments during holding a vertically oriented handle under slow, externally imposed changes in the width of the grasp. Subjects (n = 8) grasped a customized motorized handle with five digits and held it statically in the air. The handle width either increased (expanded) or dec...

journal_title：Journal of neurophysiology

authors： Zatsiorsky VM,Gao F,Latash ML

更新日期：2006-04-01 00:00:00

abstract：:1. Current- and voltage-clamp studies were conducted on isolated rat adrenal chromaffin cells to identify the voltage-dependent ion channels mediating inward currents. 2. Mean resting membrane potential of the isolated cells was -62 +/- 3 (SE) mV. Evoked action potentials were both Na+ and Ca2+ based, and whole cell v...

journal_title：Journal of neurophysiology

authors： Hollins B,Ikeda SR

更新日期：1996-08-01 00:00:00

abstract：:The function of the ventral nucleus of the lateral lemniscus (VNLL), a secondary processing site within the auditory brain stem, is unclear. It is known to be a major source of inhibition to the inferior colliculus (IC). It is also thought to play a role in coding the temporal aspects of sound, such as onsets and the ...

journal_title：Journal of neurophysiology

authors： Nayagam DA,Clarey JC,Paolini AG

更新日期：2005-08-01 00:00:00

abstract：:Neurons in area MT, a motion-sensitive area of extrastriate cortex, respond to a step of target velocity with a transient-sustained firing pattern. The transition from a high initial firing rate to a lower sustained rate occurs over a time course of 20-80 ms and is considered a form of short-term adaptation. The prese...

journal_title：Journal of neurophysiology

authors： Priebe NJ,Churchland MM,Lisberger SG

更新日期：2002-07-01 00:00:00

abstract：:Fast-spiking GABAergic interneurons of the neocortex and hippocampus fire high-frequency trains of brief action potentials with little spike-frequency adaptation. How these striking properties arise is unclear, although recent evidence suggests K(+) channels containing Kv3.1-Kv3.2 proteins play an important role. We i...

journal_title：Journal of neurophysiology

authors： Erisir A,Lau D,Rudy B,Leonard CS

更新日期：1999-11-01 00:00:00

abstract：:1. Cats were prepared for chronic recordings from the lumbar enlargement of the spinal dorsal horn. At the beginning of each recording session, a tungsten microelectrode was advanced through the dura in a physiologically intact, awake, drug-free animal, until amplitude discrimination provided a single neuron with a re...

journal_title：Journal of neurophysiology

authors： Kishikawa K,Uchida H,Yamamori Y,Collins JG

更新日期：1995-08-01 00:00:00

abstract：:Electrical transmission is a dynamically regulated form of communication and key to synchronizing neuronal activity. The bag cell neurons of Aplysia are a group of electrically coupled neuroendocrine cells that initiate ovulation by secreting egg-laying hormone during a prolonged period of synchronous firing called th...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Standage D,Groten CJ,Blohm G,Magoski NS

更新日期：2015-02-01 00:00:00

abstract：:We investigated the postnatal development of axon sensitivity to the withdrawal of oxygen, glucose, or the combined withdrawal of oxygen + glucose in the isolated rat optic nerve (a CNS white matter tract). Removal of either oxygen or glucose for 60 min resulted in irreversible injury in optic nerves from adult rats, ...

journal_title：Journal of neurophysiology

authors： Fern R,Davis P,Waxman SG,Ransom BR

更新日期：1998-01-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) is a noninvasive tool used to probe cognitive and affective processes. Although fMRI provides indirect measures of neural activity, the advent of fMRI has allowed for1) the corroboration of significant animal findings in the human brain, and2) the expansion of models to inc...

journal_title：Journal of neurophysiology

authors： Wang KS,Smith DV,Delgado MR

更新日期：2016-03-01 00:00:00

abstract：:1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

journal_title：Journal of neurophysiology

authors： Surmeier DJ,Honda CN,Willis WD Jr

更新日期：1988-03-01 00:00:00

abstract：:We introduce a new method to unveil the network connectivity among dozens of neurons in brain slice preparations. While synaptic inputs were whole cell recorded from given postsynaptic neurons, the spatiotemporal firing patterns of presynaptic neuron candidates were monitored en masse with functional multineuron calci...

journal_title：Journal of neurophysiology

authors： Sasaki T,Minamisawa G,Takahashi N,Matsuki N,Ikegaya Y

更新日期：2009-07-01 00:00:00

abstract：:Precisely synchronized neuronal activity has been commonly observed in the mammalian visual pathway. Spike timing correlations in the lateral geniculate nucleus (LGN) often take the form of phase synchronized oscillations in the high gamma frequency range. To study the relations between oscillatory activity, synchrony...

journal_title：Journal of neurophysiology

authors： Ito H,Maldonado PE,Gray CM

更新日期：2010-12-01 00:00:00

abstract：:CA1 inhibitory interneurons at the stratum lacunosum-moleculare and radiatum junction (LM/RAD-INs) display subthreshold membrane potential oscillations (MPOs) involving voltage-dependent Na(+) and A-type K(+) currents. LM/RAD-INs also express other voltage-gated K(+) currents, although their properties and role in MPO...

journal_title：Journal of neurophysiology

authors： Morin F,Haufler D,Skinner FK,Lacaille JC

更新日期：2010-06-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) receives a dense serotonergic innervation that modulates photic input to the SCN via serotonin 1B (5-HT1B) presynaptic receptors on retinal glutamatergic terminals. However, the majority of 5-HT1B binding sites in the SCN are located on nonretinal terminals and most axonal terminals i...

journal_title：Journal of neurophysiology

authors： Bramley JR,Sollars PJ,Pickard GE,Dudek FE

更新日期：2005-06-01 00:00:00

abstract：:GSG1L is an AMPA receptor (AMPAR) auxiliary subunit that regulates AMPAR trafficking and function in hippocampal CA1 pyramidal neurons. However, its physiological roles in other types of neurons remain to be characterized. Here, we investigated the role of GSG1L in hippocampal dentate granule cells and found that GSG1...

journal_title：Journal of neurophysiology

authors： Mao X,Gu X,Lu W

更新日期：2017-01-01 00:00:00

abstract：:Monitoring representative fractions of neurons from multiple brain circuits in behaving animals is necessary for understanding neuronal computation. Here, we describe a system that allows high-channel-count recordings from a small volume of neuronal tissue using a lightweight signal multiplexing headstage that permits...

journal_title：Journal of neurophysiology

authors： Berényi A,Somogyvári Z,Nagy AJ,Roux L,Long JD,Fujisawa S,Stark E,Leonardo A,Harris TD,Buzsáki G

更新日期：2014-03-01 00:00:00

abstract：:A spherical approximation technique is presented that affords a mathematical characterization of a virtual space receptive field (VSRF) based on first-spike latency in the auditory cortex of cat. Parameterizing directional sensitivity in this fashion is much akin to the use of difference-of-Gaussian (DOG) functions fo...

journal_title：Journal of neurophysiology

authors： Jenison RL,Reale RA,Hind JE,Brugge JF

更新日期：1998-11-01 00:00:00

abstract：:Detection and discrimination of odors generally, if not always, occurs against an odorous background. On any given inhalation, olfactory receptor neurons will be activated by features of both the target odorant and features of background stimuli. To identify a target odorant against a background therefore, the olfacto...

journal_title：Journal of neurophysiology

authors： Kadohisa M,Wilson DA

更新日期：2006-03-01 00:00:00

abstract：:Although fluorescence microscopy has proven to be one of the most powerful tools in biology, its application to the intact animal has been limited to imaging several hundred micrometers below the surface. The rest of the animal has eluded investigation at the microscopic level without excising tissue or performing ext...

journal_title：Journal of neurophysiology

authors： Levene MJ,Dombeck DA,Kasischke KA,Molloy RP,Webb WW

更新日期：2004-04-01 00:00:00

abstract：:1. Ca(2+)-dependent K+ currents were studied in large pyramidal neurons (Betz cells) from layer V of cat sensorimotor cortex by use of an in vitro brain slice and single microelectrode voltage clamp. The Ca(2+)-dependent outward current was taken as the difference current obtained before and after blockade of Ca2+ inf...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Spain WJ,Crill WE

更新日期：1992-01-01 00:00:00

abstract：:Humans maneuver easily over uneven terrain. To maintain smooth and efficient gait the motor system needs to adapt the locomotor output to the walking environment. In the present study we investigate the role of sensory feedback in adjusting the soleus muscle activity during overground walking in 19 healthy volunteers....

journal_title：Journal of neurophysiology

authors： Af Klint R,Nielsen JB,Sinkjaer T,Grey MJ

更新日期：2009-04-01 00:00:00

abstract：:The pacemaker current of a bursting neuron of Helix pomatia was investigated using voltage-clamp and pressure-injection techniques. In the steady state the net membrane current was zero near threshold of the action potential at -45 mV. Negative to this potential the membrane current was inward and steady. During burst...

journal_title：Journal of neurophysiology

authors： Swandulla D,Lux HD

更新日期：1985-12-01 00:00:00

abstract：:To estimate contour-orientation sensitivity of the cat and the degree to which precortical processing contributes to such estimates, the amplitude of visually evoked potentials (VEP) recorded from the visual cortex of cats in response to a visual stimulus (S2) presented at various intervals after presentation of anoth...

journal_title：Journal of neurophysiology

authors： Tootle JS,Berkley MA

更新日期：1985-05-01 00:00:00

abstract：:Memory for past events may be based on retrieval accompanied by specific contextual details (recollection) or on the feeling that an item is old (familiarity) or new (novelty) in the absence of contextual details. There are indications that recollection, familiarity, and novelty involve different medial temporal lobe ...

journal_title：Journal of neurophysiology

authors： Daselaar SM,Fleck MS,Cabeza R

更新日期：2006-10-01 00:00:00

abstract：:One feature of neuronal discharge proposed to play a role in coding temporal information is the relative refractory period that follows each action potential. In neurons innervating hair cells, there is an extended refractory period that can last

journal_title：Journal of neurophysiology

authors： Dawkins R,Sewell WF

更新日期：2004-08-01 00:00:00

abstract：:In the Aplysia mechanoafferent B21, afferent transmission is in part regulated via the control of active spike propagation. When B21 is peripherally activated at its resting membrane potential, spikes fail to propagate to an output process, and afferent transmission does not occur. In this report, we show that the pro...

journal_title：Journal of neurophysiology

authors： Evans CG,Ludwar BCh,Cropper EC

更新日期：2007-04-01 00:00:00

abstract：:Second-order vestibular neurons (2 degrees VN) were identified in the isolated frog brain by the presence of monosynaptic excitatory postsynaptic potentials (EPSPs) after separate electrical stimulation of individual vestibular nerve branches. Combinations of one macular and the three semicircular canal nerve branches...

journal_title：Journal of neurophysiology

authors： Straka H,Holler S,Goto F

更新日期：2002-11-01 00:00:00

abstract：:Synaptic transmission at the inner hair cell (IHC) afferent synapse, the first synapse in the auditory pathway, is specialized for rapid and reliable signaling. Here we investigated the properties of a hyperpolarization-activated current (I(h)), expressed in the afferent dendrite of auditory nerve fibers, and its role...

journal_title：Journal of neurophysiology

authors： Yi E,Roux I,Glowatzki E

更新日期：2010-05-01 00:00:00

abstract：:1. The effects of inhibitory postsynaptic potential (IPSP) barrages on coding of sinusoidal length inputs were investigated in slowly and rapidly adapting stretch receptors of crayfish (RM1 and RM2, respectively). To examine the contribution of postsynaptic firings, a description was obtained of the temporal correlati...

journal_title：Journal of neurophysiology

authors： Barrio LC,Buño W

更新日期：1990-06-01 00:00:00

abstract：:The responses of cortical neurons to repeated presentation of a stimulus are highly variable, yet correlated. These "noise correlations" reflect a low-dimensional structure of population dynamics. Here, we examine noise correlations in 22,705 pairs of neurons in primary visual cortex (V1) of anesthetized cats, during ...

journal_title：Journal of neurophysiology

authors： Schulz DP,Sahani M,Carandini M

更新日期：2015-08-01 00:00:00