Large-scale, high-density (up to 512 channels) recording of local circuits in behaving animals.

abstract：:There is evidence that postural instability associated with Parkinson's disease (PD) is not adequately improved by levodopa, implying involvement of nondopaminergic pathways. However, the mechanisms contributing to postural instability have yet to be fully identified and tested for their levodopa responsiveness. In th...

journal_title：Journal of neurophysiology

authors： Di Giulio I,St George RJ,Kalliolia E,Peters AL,Limousin P,Day BL

更新日期：2016-08-01 00:00:00

abstract：:Are behaviors that rely on common muscles and motoneurons generated by separate or overlapping groups of pattern-generating neurons? This question was investigated for the three forms of scratching in immobilized, spinal turtles. Individual neurons were recorded extracellularly from the gray matter through most of the...

journal_title：Journal of neurophysiology

authors： Berkowitz A

更新日期：2001-08-01 00:00:00

abstract：:1. R2 and LPl1 are homologous giant cholinergic neurons in the nervous system of Aplysia with overlapping and almost symmetrical axonal trees extending over most of the body wall. In spite of much experimental study, the behavioral role of the cells has remained unknown. 2. After intrasomatic injection of R2 and LPl1 ...

journal_title：Journal of neurophysiology

authors： Rayport SG,Ambron RT,Babiarz J

更新日期：1983-04-01 00:00:00

abstract：:The short-term (3-51 days) and long-term (31-42 wk) effects of corpus callosum transection on the receptive-field properties of neurons were assessed at the single-cell, architectural, and topographical levels of organization in the cat striate cortex. Corpus callosum transection decreased the proportion of neurons th...

journal_title：Journal of neurophysiology

authors： Payne BR,Pearson HE,Berman N

更新日期：1984-09-01 00:00:00

abstract：:The tactile sensations mediated by the whisker-trigeminal system allow rodents to efficiently detect and discriminate objects. These capabilities rely strongly on the temporal and spatial structure of whisker deflections. Subthreshold but also spiking receptive fields in the barrel cortex encompass a large number of v...

journal_title：Journal of neurophysiology

authors： Le Cam J,Estebanez L,Jacob V,Shulz DE

更新日期：2011-08-01 00:00:00

abstract：:1. Single-electrode voltage-clamp recordings were made from CA3 pyramidal cells in organotypic hippocampal slice cultures for measurement of membrane currents underlying both the gamma-aminobutyric acid (GABA)-mediated, Cl- -dependent inhibitory postsynaptic potential (IPSC), evoked in response to stimulation of the m...

journal_title：Journal of neurophysiology

authors： Thompson SM,Gähwiler BH

更新日期：1989-03-01 00:00:00

abstract：:1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...

journal_title：Journal of neurophysiology

authors： Andreasen M,Hablitz JJ

更新日期：1993-06-01 00:00:00

abstract：:When an object is lifted vertically, the normal force increases and decreases in tandem with tangential (load) force to safely avoid slips. For horizontal object transport, horizontal forces at the contact surfaces can be decomposed into manipulation forces (producing acceleration/deceleration) and grasping forces. Al...

journal_title：Journal of neurophysiology

authors： Winges SA,Soechting JF,Flanders M

更新日期：2007-08-01 00:00:00

abstract：:We examined which motor areas would participate in the coding of a simple opposition of the thumb triggered by auditory, somatosensory and visual signals. We tested which motor areas might be active in response to all three modalities, which motor structures would be activated specifically in response to each modality...

journal_title：Journal of neurophysiology

authors： Naito E,Kinomura S,Geyer S,Kawashima R,Roland PE,Zilles K

更新日期：2000-03-01 00:00:00

abstract：:Adaptation of movement may be driven by the difference between planned and actual motor performance, or the difference between expected and actual sensory consequences of movement. To identify how the nervous system differentially uses these signals, we asked: does motor adaptation occur when movement errors are irrel...

journal_title：Journal of neurophysiology

authors： Schaefer SY,Shelly IL,Thoroughman KA

更新日期：2012-02-01 00:00:00

abstract：:It is controversial whether simple-spike activity of cerebellar Purkinje cells during arm movements encodes movement kinematics like velocity or dynamics like muscle activities. To examine this issue, we trained monkeys to flex or extend the elbow by 45 degrees in 400 ms under resistive and assistive force fields but ...

journal_title：Journal of neurophysiology

authors： Yamamoto K,Kawato M,Kotosaka S,Kitazawa S

更新日期：2007-02-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:Depolarization-induced suppression of inhibition (DSI) is a form of retrograde signaling at GABAergic synapses that is initiated by the calcium- and depolarization-dependent release of endocannabinoids from postsynaptic neurons. In the neocortex, pyramidal neurons (PNs) appear to use DSI as a mechanism for regulating ...

journal_title：Journal of neurophysiology

authors： Fortin DA,Trettel J,Levine ES

更新日期：2004-10-01 00:00:00

abstract：:There are at least two respiration-related rhythm generators in the medulla: the pre-Bötzinger complex, which produces inspiratory (Insp) neuron bursts, and the parafacial respiratory group (pFRG), which produces predominantly preinspiratory (Pre-I) neuron bursts. The pFRG Pre-I neuron activity has not been correlated...

journal_title：Journal of neurophysiology

authors： Onimaru H,Kumagawa Y,Homma I

更新日期：2006-07-01 00:00:00

abstract：:The rhythmic delivery of visual stimuli evokes large-scale neuronal entrainment in the form of steady-state oscillatory field potentials. The spatiotemporal properties of stimulus drive appear to constrain the relative degrees of neuronal entrainment. Specific frequency ranges, for example, are uniquely suited for enh...

journal_title：Journal of neurophysiology

authors： Nguyen T,Kuntzelman K,Miskovic V

更新日期：2017-07-01 00:00:00

abstract：:1. The antidromic compound action potential (ACAP) of the auditory nerve was evoked by shocks to the auditory nerve root and recorded at the round window of the cochlea in anesthetized guinea pigs. The goal of this study was to determine the characteristics of the ACAP and compare these characteristics with those of t...

journal_title：Journal of neurophysiology

authors： Brown MC

更新日期：1994-05-01 00:00:00

abstract：:1. The modulation of reflex responses in up to 10 simultaneously recorded hindlimb muscles was studied in unrestrained cats walking on a treadmill. Single electrical shocks of various strengths were applied to different skin areas of teh hindlimb at different times of the step cycle while the resulting EMG responses w...

journal_title：Journal of neurophysiology

authors： Duysens J,Loeb GE

更新日期：1980-11-01 00:00:00

abstract：:The medial-olivocochlear (MOC) acoustic reflex is thought to provide frequency-specific feedback that adjusts the gain of cochlear amplification, but little is known about how frequency specific the reflex actually is. We measured human MOC tuning through changes in stimulus frequency otoacoustic emissions (SFOAEs) fr...

journal_title：Journal of neurophysiology

authors： Lilaonitkul W,Guinan JJ Jr

更新日期：2012-03-01 00:00:00

abstract：:The acid-sensing ion channels (ASICs) form cation channels that are transiently activated by extracellular protons. They are expressed in dorsal root ganglia (DRG) neurons and in the periphery where they play a function in nociception and mechanosensation. Previous studies showed that FMRFamide and related peptides po...

journal_title：Journal of neurophysiology

authors： Xie J,Price MP,Wemmie JA,Askwith CC,Welsh MJ

更新日期：2003-05-01 00:00:00

abstract：:To understand the role of primary visual cortex (V1) in color vision, we measured directly the input from the 3 cone types in macaque V1 neurons. Cells were classified as luminance-preferring, color-luminance, or color-preferring from the ratio of the peak amplitudes of spatial frequency responses to red/green equilum...

journal_title：Journal of neurophysiology

authors： Johnson EN,Hawken MJ,Shapley R

更新日期：2004-06-01 00:00:00

abstract：:We have examined the role of dorsal horn cells that respond to Lissauer tract stimulation in regulating primary afferent depolarization (PAD). PAD was monitored by recording the dorsal root potential (DRP) in the roots of the lumbar cord. Recordings were made of the discharges of Lissauer tract-responsive cells, and t...

journal_title：Journal of neurophysiology

authors： Lidierth M,Wall PD

更新日期：1998-08-01 00:00:00

abstract：:1. A 16-channel electrode array was used to record simultaneously extracellular laminar field potentials evoked by displacement of contralateral vibrissa from vibrissa/barrel cortex in five rats. Current source-density (CSD) analysis combined with principal component analysis (PCA) was used to determine the time cours...

journal_title：Journal of neurophysiology

authors： Di S,Baumgartner C,Barth DS

更新日期：1990-04-01 00:00:00

abstract：:Here we report on the development of a novel neuroelectronic interface consisting of an array of noninvasive gold-mushroom-shaped microelectrodes (gMmicroEs) that practically provide intracellular recordings and stimulation of many individual neurons, while the electrodes maintain an extracellular position. The develo...

journal_title：Journal of neurophysiology

authors： Hai A,Shappir J,Spira ME

更新日期：2010-07-01 00:00:00

abstract：:The nucleus of the solitary tract (NST) and the parabrachial nuclei (PbN) are the first and second relays in the rodent central taste pathway. A series of electrophysiological experiments revealed that spontaneous and taste-evoked activities of brain stem gustatory neurons are altered by descending input from multiple...

journal_title：Journal of neurophysiology

authors： Li CS,Lu DP,Cho YK

更新日期：2015-06-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:Muscles paralyzed by chronic (>1 yr) spinal cord injury fatigue readily. Our aim was to evaluate whether the fatigability of paralyzed thenar muscles (n = 10) could be reduced by the repeated delivery of variable versus constant frequency pulse trains. Fatigue was induced in four ways. Intermittent supramaximal median...

journal_title：Journal of neurophysiology

authors： Thomas CK,Griffin L,Godfrey S,Ribot-Ciscar E,Butler JE

更新日期：2003-04-01 00:00:00

abstract：:Self-motion generates patterns of optic flow on the retina. Neurons in the dorsal part of the medial superior temporal area (MSTd) are selective for these optic flow patterns. It has been shown that neurons in this area that are selective for expanding optic flow fields are involved in heading judgments. We wondered h...

journal_title：Journal of neurophysiology

authors： Xu H,Wallisch P,Bradley DC

更新日期：2014-06-01 00:00:00

abstract：:1. The active stiffness of ventral superficial abdominal muscle (VSM) of the hermit crab, Pagurus pollicarus, was measured with ramp stretches of different amplitudes and velocities. Active stiffness was calculated by subtracting the peak force produced by passive stretch and the isometric force just before stretch fr...

journal_title：Journal of neurophysiology

authors： Chapple WD

更新日期：1989-11-01 00:00:00

abstract：:We investigated spike-frequency adaptation of neurons sensitive to interaural phase disparities (IPDs) in the inferior colliculus (IC) of urethane-anesthetized guinea pigs using a stimulus paradigm designed to exclude the influence of adaptation below the level of binaural integration. The IPD-step stimulus consists o...

journal_title：Journal of neurophysiology

authors： Ingham NJ,McAlpine D

更新日期：2004-02-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) are known to regulate axonal refinement and dendritic branching. However, because NMDARs are abundantly present as tri-heteromers (e.g., NR1/NR2A/NR2B) during development, the precise role of the individual subunits NR2A and NR2B in these processes has not been elucidated. Ventr...

journal_title：Journal of neurophysiology

authors： Sepulveda FJ,Bustos FJ,Inostroza E,Zúñiga FA,Neve RL,Montecino M,van Zundert B

更新日期：2010-04-01 00:00:00