Maintaining balance against force perturbations: impaired mechanisms unresponsive to levodopa in Parkinson's disease.

abstract：:The ability of individuals to adapt locomotion to constraints associated with the complex environments normally encountered in everyday life is paramount for survival. Here, we tested the ability of 24 healthy young adults to adapt to a rightward prism shift (∼11.3°) while either walking and stepping to targets (i.e.,...

journal_title：Journal of neurophysiology

authors： Alexander MS,Flodin BW,Marigold DS

更新日期：2011-08-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the most common neurological disorders causing memory reduction, particularly short-term memory (STM). We showed that, during TBI-induced inflammation, increased blood content of fibrinogen (Fg) enhanced vascular protein transcytosis and deposition of extravasated Fg in vasculo-a...

journal_title：Journal of neurophysiology

authors： Charkviani M,Muradashvili N,Sulimai N,Lominadze D

更新日期：2020-08-01 00:00:00

abstract：:The motor pathway responsible for the complex vocalizations of songbirds has been extensively characterized, both in terms of intrinsic and synaptic physiology in vitro and in terms of the spatiotemporal patterns of neural activity in vivo. However, the relationship between the neural architecture of the song motor pa...

journal_title：Journal of neurophysiology

authors： Abarbanel HD,Gibb L,Mindlin GB,Talathi S

更新日期：2004-07-01 00:00:00

abstract：:Synaptic plasticity in the amygdala is thought to underlie aversive or rewarding learning and emotional memories. In this study, different mechanisms were found to underlie synaptic plasticity in lateral (LA) and basolateral (BLA) amygdala pathways to the primary output nucleus of the amygdala, the central amygdala (C...

journal_title：Journal of neurophysiology

authors： Fu Y,Shinnick-Gallagher P

更新日期：2005-05-01 00:00:00

abstract：:Microelectrode arrays (MEAs) are appealing tools to probe large neural ensembles and build neural prostheses. Microelectronics microfabrication technologies now allow building high-density MEAs containing several hundreds of microelectrodes. However, several major problems become limiting factors when the size of the ...

journal_title：Journal of neurophysiology

authors： Heim M,Rousseau L,Reculusa S,Urbanova V,Mazzocco C,Joucla S,Bouffier L,Vytras K,Bartlett P,Kuhn A,Yvert B

更新日期：2012-09-01 00:00:00

abstract：:Recent physiological studies have suggested that there are several sites of interaction between the neural pathways that control saccadic eye movements and those that control visual pursuit movements. To address the question of saccade/pursuit interaction from a neuroanatomical point of view, we have studied the conne...

journal_title：Journal of neurophysiology

authors： Yan YJ,Cui DM,Lynch JC

更新日期：2001-12-01 00:00:00

abstract：:In quadrupeds, the dorsal-side-up body orientation during standing is maintained due to a postural system that is driven by feedback signals coming mainly from limb mechanoreceptors. In caudally decerebrated (postmammillary) rabbits, the efficacy of this system is considerably reduced. In this paper, we report that th...

journal_title：Journal of neurophysiology

authors： Zelenin PV,Hsu LJ,Orlovsky GN,Deliagina TG

更新日期：2012-06-01 00:00:00

abstract：:Pathologic reorganization of spinal networks and activity-dependent plasticity are common neuronal adaptations after spinal cord injury (SCI) in humans. In this work, we examined changes of reciprocal Ia and nonreciprocal Ib inhibition after locomotor training in 16 people with chronic SCI. The soleus H-reflex depress...

journal_title：Journal of neurophysiology

authors： Knikou M,Smith AC,Mummidisetty CK

更新日期：2015-04-01 00:00:00

abstract：:The interstitial nucleus of Cajal (INC) is thought to control torsional and vertical head posture. Unilateral microstimulation of the INC evokes torsional head rotation to positions that are maintained until stimulation offset. Unilateral INC inactivation evokes head position-holding deficits with the head tilted in t...

journal_title：Journal of neurophysiology

authors： Farshadmanesh F,Chang P,Wang H,Yan X,Corneil BD,Crawford JD

更新日期：2008-09-01 00:00:00

abstract：:1. Single- and multiunit recordings were obtained from neurons in the auditory cortex of the echolocating bat Myotis lucifugus, while trains of stimuli designed to simulate the bat's frequency-modulated (FM) orientation pulse and its returning echo were delivered. It was found that many neurons in the cortex responded...

journal_title：Journal of neurophysiology

authors： Sullivan WE 3rd

更新日期：1982-10-01 00:00:00

abstract：:1. The discharge of antidromically identified medial rectus and abducens motoneurons was recorded in restrained unanesthesized goldfish during spontaneous eye movements and in response to vestibular and optokinetic stimulation. 2. All medial rectus and abducens motoneurons exhibited a similar discharge pattern. A burs...

journal_title：Journal of neurophysiology

authors： Pastor AM,Torres B,Delgado-Garcia JM,Baker R

更新日期：1991-12-01 00:00:00

abstract：:The purpose of these studies was to determine the role of gracile nucleus and the effects of l-arginine-derived nitric oxide (NO) synthesis in the nucleus on the cardiovascular responses to electroacupuncture (EA) stimulation of "Zusanli" (ST36). Arterial blood pressure and heart rate were monitored during EA stimulat...

journal_title：Journal of neurophysiology

authors： Chen S,Ma SX

更新日期：2003-08-01 00:00:00

abstract：:Sciatic nerve section (axotomy) increases the excitability of rat dorsal root ganglion (DRG) neurons. The changes in Ca2+ currents, K+ currents, Ca2+ sensitive K+ current, and hyperpolarization-activated cation current (I(H)) that may be associated with this effect were examined by whole cell recording. Axotomy affect...

journal_title：Journal of neurophysiology

authors： Abdulla FA,Smith PA

更新日期：2001-02-01 00:00:00

abstract：:1. We used transcranial magnetic stimulation (TMS) to study the role of plastic changes of the human motor system in the acquisition of new fine motor skills. We mapped the cortical motor areas targeting the contralateral long finger flexor and extensor muscles in subjects learning a one-handed, five-finger exercise o...

journal_title：Journal of neurophysiology

authors： Pascual-Leone A,Nguyet D,Cohen LG,Brasil-Neto JP,Cammarota A,Hallett M

更新日期：1995-09-01 00:00:00

abstract：:1. Responses of primary sensory neurons to substance P applications by perfusion were studied with intracellular recording techniques in in vitro slice preparations of trigeminal root ganglia (guinea pigs). Application of substance P in micromolar doses produced reversible depolarizations of 2-47 mV in 48 out of 64 ne...

journal_title：Journal of neurophysiology

authors： Spigelman I,Puil E

更新日期：1990-07-01 00:00:00

abstract：:Generalizing newly learned movement patterns beyond the training context is challenging for most motor learning situations. Here we tested whether learning of a new physical property of the arm during self-initiated reaching generalizes to new arm configurations. Human participants performed a single-joint elbow reach...

journal_title：Journal of neurophysiology

authors： Maeda RS,Zdybal JM,Gribble PL,Pruszynski JA

更新日期：2020-03-01 00:00:00

abstract：:Using whole cell recordings, I analyzed the intrinsic discharge properties for 285 neurons in Rexed's laminae III-V of isolated hamster spinal cord preparations. Neurons were characterized by their responses to step-wise and ramp-hold depolarizing current applied through the recording pipettes. Tonic cells (133/285; 4...

journal_title：Journal of neurophysiology

authors： Schneider SP

更新日期：2003-07-01 00:00:00

abstract：:Our understanding of how we learn and retain motor behaviors is still limited. For instance, there is conflicting evidence as to whether the memory of a learned visuomotor perturbation consolidates; i.e., the motor memory becomes resistant to interference from learning a competing perturbation over time. Here, we soug...

journal_title：Journal of neurophysiology

authors： Maeda RS,McGee SE,Marigold DS

更新日期：2017-01-01 00:00:00

abstract：:Rewards in the natural environment are rarely predicted with complete certainty. Uncertainty relating to future rewards has typically been defined as the variance of the potential outcomes. However, the asymmetry of predicted reward distributions, known as skewness, constitutes a distinct but neuroscientifically under...

journal_title：Journal of neurophysiology

authors： Burke CJ,Tobler PN

更新日期：2011-11-01 00:00:00

abstract：:In mesial temporal lobe (MTL) epilepsy, which typically involves the hippocampus (HPC), epileptiform events are enhanced during slow wave sleep (SWS). It remains unclear how and why the electroencephalographic (EEG) states that constitute SWS might predispose the HPC to this type of pathological activity. Recently our...

journal_title：Journal of neurophysiology

authors： Nazer F,Dickson CT

更新日期：2009-09-01 00:00:00

abstract：:During early brain development, γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, has been thought to be an important source of excitatory neurotransmission. This view, however, was recently challenged by a series of studies that claim that the excitatory effect of GABA is due to non...

journal_title：Journal of neurophysiology

authors： Khakhalin AS

更新日期：2011-09-01 00:00:00

abstract：:Inactivation permits direct assessment of the functional contribution of a given brain area to behavior. Previous inactivation studies of the frontal eye field (FEF) have either used large permanent ablations or reversible pharmacological techniques that only inactivate a small volume of tissue. Here we evaluated the ...

journal_title：Journal of neurophysiology

authors： Peel TR,Johnston K,Lomber SG,Corneil BD

更新日期：2014-01-01 00:00:00

abstract：:Complex patterns of intercellular calcium signaling occur in the CA1 and CA2 regions of hippocampal slice organotypic cultures from neonatal mice. Spontaneous localized intercellular Ca2+ waves involving 5-15 cells propagate concentrically from multiple foci in the stratum oriens and s. radiatum. In these same regions...

journal_title：Journal of neurophysiology

authors： Harris-White ME,Zanotti SA,Frautschy SA,Charles AC

更新日期：1998-02-01 00:00:00

abstract：:The core region of primate auditory cortex contains a primary and two primary-like fields (AI, primary auditory cortex; R, rostral field; RT, rostrotemporal field). Although it is reasonable to assume that multiple core fields provide an advantage for auditory processing over a single primary field, the differential r...

journal_title：Journal of neurophysiology

authors： Bendor D,Wang X

更新日期：2008-08-01 00:00:00

abstract：:Responses to tones, clicks, and noise were recorded from chinchilla auditory-nerve fibers (ANFs). The responses to noise were analyzed by computing the zeroth-, first-, and second-order Wiener kernels (h0, h1, and h2). The h1s correctly predicted the frequency tuning and phases of responses to tones of ANFs with low c...

journal_title：Journal of neurophysiology

authors： Temchin AN,Recio-Spinoso A,van Dijk P,Ruggero MA

更新日期：2005-06-01 00:00:00

abstract：:1. A network of four pairs of interneurons, HN(1)-HN(4), times the heartbeat of the medicinal leech. The following model accounts for the stable phase relationships in the network and the network's response to perturbation, entrainment, and stimulation. 2. There are two centers of oscillation, one the HN(3) pair in th...

journal_title：Journal of neurophysiology

authors： Peterson EL

更新日期：1983-03-01 00:00:00

abstract：:1. We define an extrinsic frame of reference to represent the location of a point in extrapersonal space relative to a human subject's shoulder, and we define an intrinsic frame of reference to represent the orientation of the arm and forearm. 2. We examined the relations between coordinates in the extrinsic and intri...

journal_title：Journal of neurophysiology

authors： Soechting JF,Flanders M

更新日期：1989-08-01 00:00:00

abstract：:1. A reverse correlation (6, 8, 25, 35) method is developed that allows quantitative determination of visual receptive-field structure in two spatial dimensions. This method is applied to simple cells in the cat striate cortex. 2. It is demonstrated that the reverse correlation method yields results with several desir...

journal_title：Journal of neurophysiology

authors： Jones JP,Palmer LA

更新日期：1987-12-01 00:00:00

abstract：:Monocular organization of the goldfish horizontal neural integrator was studied during spontaneous scanning saccadic and fixation behaviors. Analysis of neuronal firing rates revealed a population of ipsilateral (37%), conjugate (59%), and contralateral (4%) eye position neurons. When monocular optokinetic stimuli wer...

journal_title：Journal of neurophysiology

authors： Debowy O,Baker R

更新日期：2011-02-01 00:00:00

abstract：:Muscles paralyzed by chronic (>1 yr) spinal cord injury fatigue readily. Our aim was to evaluate whether the fatigability of paralyzed thenar muscles (n = 10) could be reduced by the repeated delivery of variable versus constant frequency pulse trains. Fatigue was induced in four ways. Intermittent supramaximal median...

journal_title：Journal of neurophysiology

authors： Thomas CK,Griffin L,Godfrey S,Ribot-Ciscar E,Butler JE

更新日期：2003-04-01 00:00:00