Bilateral saccadic deficits following large and reversible inactivation of unilateral frontal eye field.

abstract：:While it has been well established that optostatic and optokinetic cues contribute to the perception of vertical, it is unclear how the brain processes their combined presence with the nonvisual vestibular cues. Using a psychometric approach, we examined the percept of vertical in human participants (n = 17) with thei...

journal_title：Journal of neurophysiology

authors： Niehof N,Perdreau F,Koppen M,Medendorp WP

更新日期：2019-08-01 00:00:00

abstract：:Humans adopt very different head movement strategies for different gaze behaviors, for example, when playing sports versus watching sports on television. Such strategy switching appears to depend on both context and expectation of future gaze positions. Here, we explored the neural mechanisms for such behaviors by tra...

journal_title：Journal of neurophysiology

authors： Monteon JA,Avillac M,Yan X,Wang H,Crawford JD

更新日期：2012-11-01 00:00:00

abstract：:Voltage-gated Na+ channels (VGSC) are transmembrane proteins that are essential for the initiation and propagation of action potentials in neuronal excitability. Because neurons express a mixture of Na+ channel isoforms and protein kinase C (PKC) isozymes, the nature of which channel is being regulated by which PKC is...

journal_title：Journal of neurophysiology

authors： Vijayaragavan K,Boutjdir M,Chahine M

更新日期：2004-04-01 00:00:00

abstract：:Flexible behavior requires the ability to delay a response until it is appropriate. This can be achieved by holding either a sensory or a motor representation online. Here we assess whether maintenance of sensory or motor material drives the motor system to different functional states, as indexed by alterations of cor...

journal_title：Journal of neurophysiology

authors： van den Hurk P,Mars RB,van Elswijk G,Hegeman J,Pasman JW,Bloem BR,Toni I

更新日期：2007-02-01 00:00:00

abstract：:Iontophoresis of glutamate at sites on the apical dendrite 278-555 microm from the somata of rat neocortical pyramidal neurons evoked low-threshold, small, slow spikes and/or large, fast spikes in 71% of recorded cells. The amplitude of the small, slow spikes recorded at the soma averaged 9.1 mV, and their apparent th...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1997-05-01 00:00:00

abstract：:The hypocretin/orexins (Hcrt/Orxs) are hypothalamic neuropeptides that regulate stress, addiction, feeding, and arousal behaviors. They depolarize many types of central neurons and can increase [Ca2+]i in some, including those of the dorsal raphe (DR) and laterodorsal tegmental (LDT) nuclei-two structures likely to co...

journal_title：Journal of neurophysiology

authors： Kohlmeier KA,Watanabe S,Tyler CJ,Burlet S,Leonard CS

更新日期：2008-10-01 00:00:00

abstract：:Stretch reflexes contribute to arm impedance and longer-latency stretch reflexes exhibit increased sensitivity during interactions with compliant or unstable environments. This increased sensitivity is consistent with a regulation of arm impedance to compensate for decreased stability of the environment, but the speci...

journal_title：Journal of neurophysiology

authors： Krutky MA,Ravichandran VJ,Trumbower RD,Perreault EJ

更新日期：2010-01-01 00:00:00

abstract：:Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their ...

journal_title：Journal of neurophysiology

authors： Sturm JJ,Weisz CJ

更新日期：2015-11-01 00:00:00

abstract：:Responses to repeated auditory stimuli were examined in 103 neurons in the auditory region of the thalamic reticular nucleus (TRN) and in 20 medial geniculate (MGB) neurons of anesthetized rats. A further six TRN neurons were recorded from awake rats. The TRN neurons showed strong responses to the first trial and weak...

journal_title：Journal of neurophysiology

authors： Yu XJ,Xu XX,Chen X,He S,He J

更新日期：2009-02-01 00:00:00

abstract：:One of the critical factors in determining network behavior of neurons is the influence of local circuit connections among interneurons. The short-term synaptic plasticity and the subtype of presynaptic calcium channels used at local circuit connections of inhibitory interneurons in CA1 were investigated using dual wh...

journal_title：Journal of neurophysiology

authors： Ali AB

更新日期：2011-03-01 00:00:00

abstract：:During an inspiration the output of hypoglossal (XII) motoneurons (HMs) in vitro is characterized by synchronous oscillatory firing in the 20- to 40-Hz range. To maintain synchronicity it is important that the cells fire with high reliability and precision. It is not known whether the intrinsic properties of HMs are t...

journal_title：Journal of neurophysiology

authors： van Brederode JF,Berger AJ

更新日期：2008-06-01 00:00:00

abstract：:We show that fast bimanual coordinative feedback responses can be reversed with changes in task goals. Participants moved a flexible virtual object across a finish line with an upward movement of both hands. In one condition, the middle of the object had to be aligned with a spatial goal at the end of the movement. In...

journal_title：Journal of neurophysiology

authors： Diedrichsen J,Gush S

更新日期：2009-01-01 00:00:00

abstract：:1. It is widely believed that signals contributing to the receptive field surrounds of retinal bipolar cells pass from horizontal cells to bipolar cells via GABAergic synapses. To test this notion, we applied gamma-aminobutyric acid (GABA) agonists and antagonists to isolated, perfused retinas of the salamander Ambyst...

journal_title：Journal of neurophysiology

authors： Hare WA,Owen WG

更新日期：1996-09-01 00:00:00

abstract：:In free viewing, the eyes return to previously visited locations rather frequently, even though the attentional and memory-related processes controlling eye-movement show a strong antirefixation bias. To overcome this bias, a special refixation triggering mechanism may have to be recruited. We probed the neural eviden...

journal_title：Journal of neurophysiology

authors： Nikolaev AR,Meghanathan RN,van Leeuwen C

更新日期：2018-11-01 00:00:00

abstract：:The octopus cells of the posteroventral cochlear nucleus receive inputs from auditory-nerve fibers and form one of the major ascending auditory pathways. They respond to acoustic and electrical stimulation transiently and are believed to carry temporal information in the precise timing of their action potentials. The ...

journal_title：Journal of neurophysiology

authors： Cai Y,Walsh EJ,McGee J

更新日期：1997-08-01 00:00:00

abstract：:1. The aim of this study was to examine the nature of motoneuron firing-rate modulation in type-identified motor units during smoothly graded contractions of the cat medial gastrocnemius (MG) muscle evoked by stimulation of the mesencephalic locomotor region (MLR). Motoneuron discharge patterns, firing rates, and the ...

journal_title：Journal of neurophysiology

authors： Tansey KE,Botterman BR

更新日期：1996-01-01 00:00:00

abstract：:The present paper investigates the sensory-driven modulations of central pattern generator dynamics that can be expected to reproduce human behavior during rhythmic hybrid tasks. We propose a theoretical model of human sensorimotor behavior able to account for the observed data from the ball-bouncing task. The novel c...

journal_title：Journal of neurophysiology

authors： Avrin G,Siegler IA,Makarov M,Rodriguez-Ayerbe P

更新日期：2017-10-01 00:00:00

abstract：:Tissue injury in early life can produce distinctive effects on pain processing, but little is known about the underlying neural mechanisms. Neonatal inflammation modulates excitatory synapses in spinal nociceptive circuits, but it is unclear whether this results directly from altered afferent input. Here we investigat...

journal_title：Journal of neurophysiology

authors： Li J,Walker SM,Fitzgerald M,Baccei ML

更新日期：2009-10-01 00:00:00

abstract：:In this report, we provide the first characterization of abducens nucleus neuron (ABN) discharge dynamics during horizontal disjunctive saccades. These movements function to rapidly transfer the visual axes between targets located at different eccentricities and depths. Our primary objective was to determine whether t...

journal_title：Journal of neurophysiology

authors： Sylvestre PA,Cullen KE

更新日期：2002-12-01 00:00:00

abstract：:The discharge of muscle spindle afferents from monkey spindle afferents from monkey jaw-closing muscles was studied during mastication of natural foods by extracellular recording from the fibers or cell bodies of the tract and mesencephalic nucleus of the fifth nerve. In all, 39 muscle afferents were studied. The spin...

journal_title：Journal of neurophysiology

authors： Goodwin GM,Luschei ES

更新日期：1975-05-01 00:00:00

abstract：:Transient neurophysiological changes in CA3 neurons and dentate granule cells after severe forebrain ischemia in vivo. J. Neurophysiol. 80: 2860-2869, 1998. The spontaneous activities, evoked synaptic responses, and membrane properties of CA3 pyramidal neurons and dentate granule cells in rat hippocampus were compared...

journal_title：Journal of neurophysiology

authors： Gao TM,Howard EM,Xu ZC

更新日期：1998-12-01 00:00:00

abstract：:Dual whole cell patch-clamp recordings in rat nucleus accumbens, the main component of the ventral striatum, were made to assess the presence of synaptic interconnections between medium-sized spiny neurons, a group of GABAergic and peptidergic neurons that constitute the principal cells of the striatum. Neurons were s...

journal_title：Journal of neurophysiology

authors： Taverna S,van Dongen YC,Groenewegen HJ,Pennartz CM

更新日期：2004-03-01 00:00:00

abstract：:The exercise pressor reflex, a crucial component of the cardiovascular response under physiological and pathophysiological states, is activated via metabolic and mechanical mediators that originate from contracting muscles and stimulate group III and IV afferents. We reported previously that stimulation of mu opioid r...

journal_title：Journal of neurophysiology

authors： Hassan B,Kim JS,Farrag M,Kaufman MP,Ruiz-Velasco V

更新日期：2014-12-15 00:00:00

abstract：:In big brown bats, tone-specific plastic changes [best frequency (BF) shifts] of cortical and collicular neurons can be evoked by auditory fear conditioning, repetitive acoustic stimuli or cortical electric stimulation. It has been shown that acetylcholine (ACh) plays an important role in evoking large long-term corti...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N,Gao E

更新日期：2005-08-01 00:00:00

abstract：:Squirrel monkeys were trained using newly developed visual-vestibular mismatch paradigms to test the asymmetrical simultaneous induction of vertical vestibuloocular reflex (VOR) gain changes in opposite directions (high and low) either in the upward and downward directions or in response to high- and low-frequency sti...

journal_title：Journal of neurophysiology

authors： Hirata Y,Lockard JM,Highstein SM

更新日期：2002-12-01 00:00:00

abstract：:Previous studies have shown that daily, moderate-level sound exposure, or conditioning, can reduce injury from a subsequent high-level noise exposure. We tested the hypothesis that this conditioning produces an increased activity in the olivocochlear efferent reflex, a reflex known to provide protection to the cochlea...

journal_title：Journal of neurophysiology

authors： Brown MC,Kujawa SG,Liberman MC

更新日期：1998-06-01 00:00:00

abstract：:1. This study was undertaken to investigate the effects of adriamycin (ADM, Doxorubicin) on the basic electrophysiological properties of spinal cord motoneurons in the adult cat. ADM was injected into the biceps, gastrocnemius, semitendinosus, and semimembranosus muscles of the left hindlimb (1.2 mg per muscle). Intra...

journal_title：Journal of neurophysiology

authors： Liu RH,Yamuy J,Xi MC,Morales FR,Chase MH

更新日期：1995-11-01 00:00:00

abstract：:1. A 16-channel electrode array was used to record simultaneously extracellular laminar field potentials evoked by displacement of contralateral vibrissa from vibrissa/barrel cortex in five rats. Current source-density (CSD) analysis combined with principal component analysis (PCA) was used to determine the time cours...

journal_title：Journal of neurophysiology

authors： Di S,Baumgartner C,Barth DS

更新日期：1990-04-01 00:00:00

abstract：:Using CFos-EGFP transgenic mice (P6-P12), we targeted persistent inward current (PIC) in the spinal interneurons activated by locomotion. Following a locomotor task, whole cell patch-clamp recordings were obtained from ventral EGFP+ neurons in spinal cord slices (200-250 μm from T₁₃-L₄). PIC was recorded by a family o...

journal_title：Journal of neurophysiology

authors： Dai Y,Jordan LM

更新日期：2010-04-01 00:00:00

abstract：:Fear conditioning studies have led to the view that the amygdala contains neurons that signal threat and in turn elicit defensive behaviors through their brain stem and hypothalamic targets. In agreement with this model, a prior unit-recording study in rats performing a seminaturalistic foraging task revealed that man...

journal_title：Journal of neurophysiology

authors： Amir A,Kyriazi P,Lee SC,Headley DB,Paré D

更新日期：2019-05-01 00:00:00