Abstract:
:Synaptic plasticity in the amygdala is thought to underlie aversive or rewarding learning and emotional memories. In this study, different mechanisms were found to underlie synaptic plasticity in lateral (LA) and basolateral (BLA) amygdala pathways to the primary output nucleus of the amygdala, the central amygdala (CeA). Specifically, 1) long-term potentiation (LTP) at the BLA-CeA synapses was independent of inhibition and mediated through N-methyl-d-aspartate receptors (NMDARs) and L-type voltage-gated calcium channels (VGCCs), and 2) LTP in the LA-CeA pathway was gated by inhibition and mediated through VGCCs but not NMDARs.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Fu Y,Shinnick-Gallagher Pdoi
10.1152/jn.00871.2004subject
Has Abstractpub_date
2005-05-01 00:00:00pages
3012-5issue
5eissn
0022-3077issn
1522-1598pii
00871.2004journal_volume
93pub_type
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