Two intra-amygdaloid pathways to the central amygdala exhibit different mechanisms of long-term potentiation.

Abstract:

:Synaptic plasticity in the amygdala is thought to underlie aversive or rewarding learning and emotional memories. In this study, different mechanisms were found to underlie synaptic plasticity in lateral (LA) and basolateral (BLA) amygdala pathways to the primary output nucleus of the amygdala, the central amygdala (CeA). Specifically, 1) long-term potentiation (LTP) at the BLA-CeA synapses was independent of inhibition and mediated through N-methyl-d-aspartate receptors (NMDARs) and L-type voltage-gated calcium channels (VGCCs), and 2) LTP in the LA-CeA pathway was gated by inhibition and mediated through VGCCs but not NMDARs.

journal_name

J Neurophysiol

authors

Fu Y,Shinnick-Gallagher P

doi

10.1152/jn.00871.2004

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

3012-5

issue

5

eissn

0022-3077

issn

1522-1598

pii

00871.2004

journal_volume

93

pub_type

杂志文章
  • Two-dimensional saccade-related population activity in superior colliculus in monkey.

    abstract::The two-dimensional distribution of population activity in the superior colliculus (SC) during saccadic eye movements in the monkey was estimated using radial basis functions. To make these ensemble activity estimates, cells in the deeper layers of the SC were recorded over much of the rostrocaudal (caudal to 3.8 mm f...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.80.2.798

    authors: Anderson RW,Keller EL,Gandhi NJ,Das S

    更新日期:1998-08-01 00:00:00

  • Preserved high-centrality hubs but efficient network reorganization during eyes-open state compared with eyes-closed resting state: an MEG study.

    abstract::A question to be addressed in the present study is how different the eyes-closed (EC) and eyes-open (EO) resting states are across frequency bands in terms of efficiency and centrality of the brain functional network. We investigated both the global and nodal efficiency and betweenness centrality in the EC and EO rest...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00585.2013

    authors: Jin SH,Jeong W,Lee DS,Jeon BS,Chung CK

    更新日期:2014-04-01 00:00:00

  • Bimodal modulation of background activity in an identified descending interneuron.

    abstract::In the absence of any obvious input, sensory neurons and interneurons can display resting or spontaneous activity. This is often regarded as noise and removed through trial averaging, although it may reflect history-dependent modulation of tuning or fidelity and, thus, be of functional relevance to downstream interneu...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00864.2018

    authors: Lepreux G,Haupt SS,Dürr V

    更新日期:2019-12-01 00:00:00

  • Cholinergic modulation of response gain in the primary visual cortex of the macaque.

    abstract::ACh modulates neuronal activity throughout the cerebral cortex, including the primary visual cortex (V1). However, a number of issues regarding this modulation remain unknown, such as the effect and its function and the receptor subtypes involved. To address these issues, we combined extracellular single-unit recordin...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00330.2011

    authors: Soma S,Shimegi S,Osaki H,Sato H

    更新日期:2012-01-01 00:00:00

  • L-type calcium channel-dependent inhibitory plasticity in the thalamus.

    abstract::Thalamocortical neurons integrate sensory and cortical activity and are regulated by input from inhibitory neurons in the thalamic reticular nucleus. Evidence suggests that during bursts of action potentials, dendritic calcium transients are seen throughout the dendritic tree of thalamocortical cells. Here, we review ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章,评审

    doi:10.1152/jn.00918.2013

    authors: Hulme SR,Connelly WM

    更新日期:2014-11-01 00:00:00

  • Contribution of primate magnocellular red nucleus to timing of hand preshaping during reaching to grasp.

    abstract::Magnocellular red nucleus (RNm) is involved in controlling goal-directed limb movements such as reaching to grasp. We tested two hypotheses related to RNm's role in controlling reach-to-grasp movements. One hypothesis is that forelimb RNm neurons are grasp specific, and the other is that they specify the timing of met...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00038.2001

    authors: Van Kan PL,McCurdy ML

    更新日期:2002-03-01 00:00:00

  • Distinct contributions of explicit and implicit memory processes to weight prediction when lifting objects and judging their weights: an aging study.

    abstract::Weight predictions used to scale lifting forces adapt quickly when repeatedly lifting unusually weighted objects and are readily updated by explicit information provided about weight. In contrast, weight predictions used when making perceptual judgments about weight are more resistant to change and are largely unaffec...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01051.2015

    authors: Trewartha KM,Flanagan JR

    更新日期:2016-09-01 00:00:00

  • Resurgent Na currents in four classes of neurons of the cerebellum.

    abstract::Action potential firing rates are generally limited by the refractory period, which depends on the recovery from inactivation of voltage-gated Na channels. In cerebellar Purkinje neurons, the kinetics of Na channels appear specialized for rapid firing. Upon depolarization, an endogenous open-channel blocker rapidly te...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00261.2004

    authors: Afshari FS,Ptak K,Khaliq ZM,Grieco TM,Slater NT,McCrimmon DR,Raman IM

    更新日期:2004-11-01 00:00:00

  • Level dependence of cochlear nucleus onset unit responses and facilitation by second tones or broadband noise.

    abstract::1. The responses of onset units in the cochlear nucleus of the anesthetized guinea pig have been measured to single tones, two-tone complexes, and broadband noise (BBN; 20-kHz bandwidth). The onset units were subdivided into three groups, onset-I (OnI), onset-L (OnL), and onset-C (OnC), on the basis of a decision tree...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.73.1.141

    authors: Winter IM,Palmer AR

    更新日期:1995-01-01 00:00:00

  • Brief trains of action potentials enhance pyramidal neuron excitability via endocannabinoid-mediated suppression of inhibition.

    abstract::Depolarization-induced suppression of inhibition (DSI) is a form of retrograde signaling at GABAergic synapses that is initiated by the calcium- and depolarization-dependent release of endocannabinoids from postsynaptic neurons. In the neocortex, pyramidal neurons (PNs) appear to use DSI as a mechanism for regulating ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00351.2004

    authors: Fortin DA,Trettel J,Levine ES

    更新日期:2004-10-01 00:00:00

  • Neuromuscular abnormalities associated with spasticity of upper extremity muscles in hemiparetic stroke.

    abstract::Our objective was to assess the mechanical changes associated with spasticity in elbow muscles of chronic hemiparetic stroke survivors and to compare these changes with those recorded in the ankle muscles of a similar cohort. We first characterized elbow dynamic stiffness by applying pseudorandom binary positional per...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00049.2007

    authors: Mirbagheri MM,Settle K,Harvey R,Rymer WZ

    更新日期:2007-08-01 00:00:00

  • Extraretinal inputs to neurons in the rostral superior colliculus of the monkey during smooth-pursuit eye movements.

    abstract::The intermediate and deep layers of the monkey superior colliculus (SC) are known to be important for the generation of saccadic eye movements. Recent studies have also provided evidence that the rostral SC might be involved in the control of pursuit eye movements. However, because rostral SC neurons respond to visual...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.86.5.2629

    authors: Krauzlis RJ

    更新日期:2001-11-01 00:00:00

  • Multisensory enhancement in the optic tectum of the barn owl: spike count and spike timing.

    abstract::Temporal and spatial correlations between auditory and visual stimuli facilitate the perception of unitary events and improve behavioral responses. However, it is not clear how combined visual and auditory information is processed in single neurons. Here we studied responses of multisensory neurons in the barn owl's o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.91193.2008

    authors: Zahar Y,Reches A,Gutfreund Y

    更新日期:2009-05-01 00:00:00

  • Single olivocochlear neurons in the guinea pig. II. Response plasticity due to noise conditioning.

    abstract::Previous studies have shown that daily, moderate-level sound exposure, or conditioning, can reduce injury from a subsequent high-level noise exposure. We tested the hypothesis that this conditioning produces an increased activity in the olivocochlear efferent reflex, a reflex known to provide protection to the cochlea...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.79.6.3088

    authors: Brown MC,Kujawa SG,Liberman MC

    更新日期:1998-06-01 00:00:00

  • Voltage-dependent, pertussis toxin insensitive inhibition of calcium currents by histamine in bovine adrenal chromaffin cells.

    abstract::Histamine is a known secretagogue in adrenal chromaffin cells. Activation of G-protein linked H(1) receptors stimulates phospholipase C, which generates inositol trisphosphate leading to release of intracellular calcium stores and stimulation of calcium influx through store operated and other channels. This calcium le...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2000.83.3.1435

    authors: Currie KP,Fox AP

    更新日期:2000-03-01 00:00:00

  • Vestibular modulation of muscle sympathetic nerve activity assessed over a 100-fold frequency range of sinusoidal galvanic vestibular stimulation.

    abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered at 0.2-2.0 Hz, evokes a partial entrainment of muscle sympathetic nerve activity (MSNA). Moreover, at lower frequencies of stimulation (0.08-0.18 Hz) sGVS produces two peaks of modulation: one (primary) peak associated with the ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00679.2018

    authors: Singh N,Hammam E,Macefield VG

    更新日期:2019-05-01 00:00:00

  • Modulation of sympathetic and somatomotor function by the ventromedial medulla.

    abstract::The ventromedial medulla is implicated in a variety of functions including nociceptive and cardiovascular modulation and the control of thermoregulation. To determine whether single microinjections into the ventromedial medulla elicit changes in one or multiple functional systems, the GABA(A) receptor antagonist bicuc...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00089.2004

    authors: Nason MW Jr,Mason P

    更新日期:2004-07-01 00:00:00

  • Layer-specific modulation of entorhinal cortical excitability by presubiculum in a rat model of temporal lobe epilepsy.

    abstract::Temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults and is often refractory to antiepileptic medications. The medial entorhinal area (MEA) is affected in TLE but mechanisms underlying hyperexcitability of MEA neurons require further elucidation. Previous studies suggest that inputs from the pres...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00823.2015

    authors: Abbasi S,Kumar SS

    更新日期:2015-11-01 00:00:00

  • [K+]o clearance in cortex: a new analytical model.

    abstract::1. It has been suggested that passive diffusion is the principal mechanism of the clearance of locally elevated extracellular potassium, K+o, in the cerebral cortex. This concept was based on the assumption that elevated K+ could be modeled as a point source. In the present study, the functional role of passive diffus...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1977.40.5.1015

    authors: Vern BA,Schuette WH,Thibault LE

    更新日期:1977-09-01 00:00:00

  • Effects on wrist and digit muscle activity from microstimuli applied at the sites of rubromotoneuronal cells in primates.

    abstract::1. The purpose of this study was to use the techniques of spike- and stimulus-triggered averaging (SpTA and StTA, respectively) to examine the output organization of individual rubromotoneuronal (RM) cells in relation to clusters of neighboring cells. SpTA of electromyographic (EMG) activity in awake monkeys reveals t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.66.6.1978

    authors: Cheney PD,Mewes K,Widener G

    更新日期:1991-12-01 00:00:00

  • Mechanosensitive properties of gastric vagal afferent fibers in the rat.

    abstract::Single, teased fiber recordings were made from the decentralized right cervical vagus nerve (hyponodal) of the rat. A total of 67 afferent fibers that responded to gastric distension (GD) were studied: 9 fibers were stimulated by phasic balloon GD, 58 by more natural fluid GD. All balloon GD-responsive fibers had rest...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.82.5.2210

    authors: Ozaki N,Sengupta JN,Gebhart GF

    更新日期:1999-11-01 00:00:00

  • Locomotor kinematics and EMG activity during quadrupedal versus bipedal gait in the Japanese macaque.

    abstract::Several qualitative features distinguish bipedal from quadrupedal locomotion in mammals. In this study we show quantitative differences between quadrupedal and bipedal gait in the Japanese monkey in terms of gait patterns, trunk/hindlimb kinematics, and electromyographic (EMG) activity, obtained from 3 macaques during...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00803.2018

    authors: Higurashi Y,Maier MA,Nakajima K,Morita K,Fujiki S,Aoi S,Mori F,Murata A,Inase M

    更新日期:2019-07-01 00:00:00

  • Adjustments of motor pattern for load compensation via modulated activations of muscle synergies during natural behaviors.

    abstract::It has been suggested that the motor system may circumvent the difficulty of controlling many degrees of freedom in the musculoskeletal apparatus by generating motor outputs through a combination of discrete muscle synergies. How a discretely organized motor system compensates for diverse perturbations has remained el...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01387.2007

    authors: Cheung VC,d'Avella A,Bizzi E

    更新日期:2009-03-01 00:00:00

  • Instructed delay discharge in primary and secondary somatosensory cortex within the context of a selective attention task.

    abstract::The neuronal mechanisms that contribute to tactile perception were studied using single-unit recordings from the cutaneous hand representation of primate primary (S1) and secondary (S2) somatosensory cortex. This study followed up on our recent observation that S1 and S2 neurons developed a sustained change in dischar...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.91121.2008

    authors: Meftah el-M,Bourgeon S,Chapman CE

    更新日期:2009-05-01 00:00:00

  • Responses of neurons in the gracile nucleus of cats to innocuous and noxious stimuli: basic characterization and antidromic activation from the thalamus.

    abstract::1. Responses to innocuous and noxious mechanical and thermal stimuli were recorded from 90 neurons in the gracile nucleus of anesthetized cats. Cells were tested by antidromic activation for projections to the contralateral ventrobasal thalamus. 2. Cells were characterized broadly by their responses to mechanical stim...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.3.818

    authors: Cliffer KD,Hasegawa T,Willis WD

    更新日期:1992-09-01 00:00:00

  • Potassium currents in octopus cells of the mammalian cochlear nucleus.

    abstract::Octopus cells in the posteroventral cochlear nucleus (PVCN) of mammals are biophysically specialized to detect coincident firing in the population of auditory nerve fibers that provide their synaptic input and to convey its occurrence with temporal precision. The precision in the timing of action potentials depends on...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.86.5.2299

    authors: Bal R,Oertel D

    更新日期:2001-11-01 00:00:00

  • Selection and coordination of human locomotor forms following cerebellar damage.

    abstract::We have previously shown that control subjects use two distinct temporal strategies when stepping on an inclined surface during walking: one for level and 10 degrees surfaces and another for 20 and 30 degrees surfaces. These two temporal strategies were characterized by systematic shifts in the timing of muscle activi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.85.2.759

    authors: Earhart GM,Bastian AJ

    更新日期:2001-02-01 00:00:00

  • Morphology and axonal projection patterns of individual neurons in the cat perigeniculate nucleus.

    abstract::1. The lateral geniculate nucleus is the primary thalamic relay through which retinal signals pass en route to cortex. This relay is gated and can be suppressed by activity among local inhibitory neurons that use gamma-aminobutyric acid (GABA) as a neurotransmitter. In the cat, a major source of this GABAergic inhibit...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.6.1528

    authors: Uhlrich DJ,Cucchiaro JB,Humphrey AL,Sherman SM

    更新日期:1991-06-01 00:00:00

  • Early postnatal switch in GABAA receptor α-subunits in the reticular thalamic nucleus.

    abstract::The GABAergic neurons of the thalamic reticular nucleus (nRt) provide the primary source of inhibition within the thalamus. Using physiology, pharmacology, and immunohistochemistry in mice, we characterized postsynaptic developmental changes in these inhibitory projection neurons. First, at postnatal days 3-5 (P3-5), ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00905.2015

    authors: Pangratz-Fuehrer S,Sieghart W,Rudolph U,Parada I,Huguenard JR

    更新日期:2016-03-01 00:00:00

  • Modulation of membrane potential in mesothoracic moto- and interneurons during stick insect front-leg walking.

    abstract::During walking, maintenance and coordination of activity in leg motoneurons requires intersegmental signal transfer. In a semi-intact preparation of the stick insect, we studied membrane potential modulations in mesothoracic (middle leg) motoneurons and local premotor nonspiking interneurons that were induced by stepp...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00493.2005

    authors: Ludwar BCh,Westmark S,Büschges A,Schmidt J

    更新日期:2005-10-01 00:00:00