Cholinergic modulation of response gain in the primary visual cortex of the macaque.

abstract：:1. The discharges from individual Golgi tendon organs of peroneus tertius and brevis muscles were recorded in anesthetized cats. Responses to unfused isometric contractions of single motor units and combinations of motor units were compared with responses to contractions eliciting muscle shortening (i.e., shortening c...

journal_title：Journal of neurophysiology

authors： Horcholle-Bossavit G,Jami L,Petit J,Vejsada R,Zytnicki D

更新日期：1988-05-01 00:00:00

abstract：:Arrays of closely spaced quartz-insulated, platinum-tungsten microelectrodes are widely used to obtain acute recordings from chronically prepared subjects. These electrodes have excellent recording characteristics and can be fabricated to a wide variety of tip specifications. Typically, in such experiments, electrodes...

journal_title：Journal of neurophysiology

authors： Swadlow HA,Bereshpolova Y,Bezdudnaya T,Cano M,Stoelzel CR

更新日期：2005-05-01 00:00:00

abstract：:Primates can generate accurate, smooth eye-movement responses to moving target objects of arbitrary shape and size, even in the presence of complex backgrounds and/or the extraneous motion of non-target objects. Most previous studies of pursuit have simply used a spot moving over a featureless background as the target...

journal_title：Journal of neurophysiology

authors： Masson GS,Stone LS

更新日期：2002-11-01 00:00:00

abstract：:The completion of an antisaccade (i.e., a nonstandard task) lengthens the reaction time (RT) of a subsequent prosaccade: a behavioral phenomenon termed the unidirectional prosaccade switch-cost. One explanation for the unidirectional prosaccade switch-cost is suppressing a stimulus-driven prosaccade during the precedi...

journal_title：Journal of neurophysiology

authors： Weiler J,Heath M

更新日期：2014-11-01 00:00:00

abstract：:Individuation refers to individuals' use of spatial and temporal properties to register an object as a distinct perceptual event relative to other stimuli. Although behavioral studies have examined both spatial and temporal individuation, neuroimaging investigations of individuation have been restricted to the spatial...

journal_title：Journal of neurophysiology

authors： Naughtin CK,Tamber-Rosenau BJ,Dux PE

更新日期：2014-02-01 00:00:00

abstract：:Controlled whisker stimulation and single-unit recordings were used to elucidate response transformations that occur during the processing of tactile information from ventral posterior medial thalamus (VPM) through cortical columns in the rat whisker/barrel cortex. Whiskers were either deflected alone, using punctate ...

journal_title：Journal of neurophysiology

authors： Brumberg JC,Pinto DJ,Simons DJ

更新日期：1999-10-01 00:00:00

abstract：:The goal of this study was to characterize the effects of corticotrophin-releasing factor (CRF) on rat paraventricular nucleus (PVN) putative parvocellular neurons using whole cell patch-clamp recordings and single-cell reverse transcription-multiplex polymerase chain reaction (single-cell RT-mPCR) techniques. Under c...

journal_title：Journal of neurophysiology

authors： Qiu DL,Chu CP,Shirasaka T,Tsukino H,Nakao H,Kato K,Kunitake T,Katoh T,Kannan H

更新日期：2005-07-01 00:00:00

abstract：:1. A quantitative analysis of facilitation during the kindling stimulation to the amygdala was conducted by measuring the area between the excitatory potential and the baseline in the averaged tetanic response recorded at the entorhinal cortex. The changes in facilitation were then compared with the development of ele...

journal_title：Journal of neurophysiology

authors： Matsuura S,Hirayama K,Murata R

更新日期：1993-08-01 00:00:00

abstract：:1. Single-electrode voltage-clamp recordings were made from CA3 pyramidal cells in organotypic hippocampal slice cultures for measurement of membrane currents underlying both the gamma-aminobutyric acid (GABA)-mediated, Cl- -dependent inhibitory postsynaptic potential (IPSC), evoked in response to stimulation of the m...

journal_title：Journal of neurophysiology

authors： Thompson SM,Gähwiler BH

更新日期：1989-03-01 00:00:00

abstract：:Animal studies have suggested that tissue injury-related increased levels of glutamate may be involved in peripheral nociceptive mechanisms in deep craniofacial tissues. Indeed, injection of glutamate (0.1-1 M, 10 microl) into the temporomandibular region evokes reflex jaw muscle responses through activation of periph...

journal_title：Journal of neurophysiology

authors： Cairns BE,Hu JW,Arendt-Nielsen L,Sessle BJ,Svensson P

更新日期：2001-08-01 00:00:00

abstract：:Rodents shift their nose from side to side when they actively explore and lateralize odors in the space. This motor action is driven by a pair of muscles, the deflector nasi. We studied the premotor control of this motion. We used replication-competent rabies virus to transsynaptically label inputs to the deflector na...

journal_title：Journal of neurophysiology

authors： Kurnikova A,Deschênes M,Kleinfeld D

更新日期：2019-01-01 00:00:00

abstract：:Seizures may cause brain damage due to mechanisms initiated by excessive excitatory synaptic transmission. One such mechanism is the activation of death-promoting intracellular cascades by the influx and the perturbed homeostasis of Ca2+. The neuroprotective effects of preventing the entry of Ca2+ from voltage-depende...

journal_title：Journal of neurophysiology

authors： Pelletier MR,Wadia JS,Mills LR,Carlen PL

更新日期：1999-06-01 00:00:00

abstract：:1. Hindlimb paw-shake responses were assessed before and after unilateral deafferentation (L3-S1) in chronic-spinal cats (n = 5), spinalized at the T12 level 1 yr earlier. Selected ankle flexor [tibialis anterior (TA)] and extensor [lateral gastrocnemius (LG)] and knee extensor [vastus lateralis (VL)] muscles were sur...

journal_title：Journal of neurophysiology

authors： Koshland GF,Smith JL

更新日期：1989-07-01 00:00:00

abstract：:Individuals with cerebral palsy (CP) experience impairments in the control of head and neck movements, suggesting dysfunction in brain stem circuitry. To examine if brain stem circuitry is altered in CP, we compared reflexes evoked in the sternocleidomastoid (SCM) muscle by trigeminal nerve stimulation in adults with ...

journal_title：Journal of neurophysiology

authors： Smith AT,Gorassini MA

更新日期：2018-09-01 00:00:00

abstract：:Primary afferent fibers from the electroreceptors of mormyrid electric fish use a latency code to signal the intensity of electrical current evoked by the fish's own electric organ discharge (EOD). The afferent fibers terminate centrally in the deep and superficial granular layers of the electrosensory lobe with morph...

journal_title：Journal of neurophysiology

authors： Zhang J,Han VZ,Meek J,Bell CC

更新日期：2007-03-01 00:00:00

abstract：:Pioneering studies demonstrated that novel degrees of freedom could be controlled individually by directly encoding the firing rate of single motor cortex neurons, without regard to each neuron's role in controlling movement of the native limb. In contrast, recent brain-computer interface work has emphasized decoding ...

journal_title：Journal of neurophysiology

authors： Law AJ,Rivlis G,Schieber MH

更新日期：2014-09-15 00:00:00

abstract：:Visual object information is conveyed from V1 to area TE along the ventral visual pathway with increasing receptive field (RF) sizes. The RFs of TE neurons are known to be large, but it is largely unknown how large RFs are shaped along the ventral visual pathway. In this study, we addressed this question in two aspect...

journal_title：Journal of neurophysiology

authors： Obara K,O'Hashi K,Tanifuji M

更新日期：2017-10-01 00:00:00

abstract：:Dopaminergic modulation produces a variety of functional changes in the principal cell of the striatum, the medium spiny neuron (MSN). Using a 189-compartment computational model of a ventral striatal MSN, we simulated whole cell D1- and D2-receptor-mediated modulation of both intrinsic (sodium, calcium, and potassium...

journal_title：Journal of neurophysiology

authors： Moyer JT,Wolf JA,Finkel LH

更新日期：2007-12-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) are comprised of different subunits. NR2 subunits confer different pharmacological and biophysical properties to NMDARs. Although NR2B subunit expression is uniform throughout striatum, NR2A subunit expression is greater laterally. Pharmacologically isolated NMDAR-mediated excit...

journal_title：Journal of neurophysiology

authors： Chapman DE,Keefe KA,Wilcox KS

更新日期：2003-01-01 00:00:00

abstract：:When a movement results in error, the nervous system amends the motor commands that generate the subsequent movement. Here we show that this adaptation depends not just on error, but also on passage of time between the two movements. We observed that subjects learned a reaching task faster, i.e., with fewer trials, wh...

journal_title：Journal of neurophysiology

authors： Huang VS,Shadmehr R

更新日期：2007-06-01 00:00:00

abstract：:The GABA withdrawal syndrome (GWS) is a model of local status epilepticus consecutive to the interruption of a prolonged GABA infusion into the rat somatomotor cortex. Bursting patterns in slices from GWS rats include intrinsic bursts of action potentials (APs) induced by intracellular depolarizing current injection a...

journal_title：Journal of neurophysiology

authors： Silva-Barrat C,Szente M,Menini C,Velluti JC,Champagnat J

更新日期：2001-05-01 00:00:00

abstract：:Gamma-aminobutyric acid type A (GABAA) receptors expressed within the medial preoptic area (mPOA) are known to play a critical role in regulating sexual and neuroendocrine functions. In the rat brain, high levels of expression of the gamma1 subunit mRNA of the GABAA receptor are restricted to a limited number of regio...

journal_title：Journal of neurophysiology

authors： Nett ST,Jorge-Rivera JC,Myers M,Clark AS,Henderson LP

更新日期：1999-01-01 00:00:00

abstract：:Voltage-activated currents in blue cones of the retinal slice of zebrafish were characterized using whole cell recording techniques. Depolarizing-elicited currents were recorded: an outward tetraethylammonium (TEA)-sensitive K+ current (IKx), an outward Ca(2+)-activated Cl- current (ICl(Ca)), from which we inferred an...

journal_title：Journal of neurophysiology

authors： Fan SF,Yazulla S

更新日期：1997-03-01 00:00:00

abstract：:1. The inhibitory response of exogenously applied glycine was investigated in freshly dissociated rat nucleus tractus solitarii neurons under whole cell configuration using new perforated patch-clamp technique termed "gramicidin perforated patch technique," which maintains intact intracellular Cl- concentrations. 2. U...

journal_title：Journal of neurophysiology

authors： Rhee JS,Ebihara S,Akaike N

更新日期：1994-09-01 00:00:00

abstract：:Morphine remains widely used in clinical settings due to its potent analgesic properties. However, one of the gravest risks of all opioids is their ability to induce respiratory depression and subsequent brain hypoxia that can lead to coma and death. Due to these life-threatening effects, our goal was to examine the e...

journal_title：Journal of neurophysiology

authors： Solis E Jr,Afzal A,Kiyatkin EA

更新日期：2018-11-01 00:00:00

abstract：:Swallow-evoked potentials in the preganglionic vagal fibers were studied using the single-fiber recording technique in anesthetized opossums. Swallows were evoked by tactile pharyngeal stimulation or electrical stimulation of the cut central end of the superior laryngeal nerve (SLN). Swallowing activity was recorded b...

journal_title：Journal of neurophysiology

authors： Gidda JS,Goyal RK

更新日期：1984-12-01 00:00:00

abstract：:Astrocyte-derived lactate supports pathologically enhanced neuronal metabolism, but its role under physiological conditions is still a matter of debate. Here, we determined the contribution of astrocytic neuronal lactate shuttle for maintenance of ion homeostasis and energy metabolism. We tested for the effects of α-c...

journal_title：Journal of neurophysiology

authors： Angamo EA,Rösner J,Liotta A,Kovács R,Heinemann U

更新日期：2016-11-01 00:00:00

abstract：:The corticotectal influences of somatosensory cortex were investigated by using reversible deactivation of cortex by cooling. More than half of the somatosensory superior colliculus (SC) cells studied exhibited a response depression (often not apparent qualitatively) or an elimination of responses to somatosensory sti...

journal_title：Journal of neurophysiology

authors： Clemo HR,Stein BE

更新日期：1986-06-01 00:00:00

abstract：:Leopard frog saccular hair cells exhibit an electrical resonance in response to a depolarizing stimulus that has been proposed to contribute to the tuning properties of the frog sacculus by acting as an electrical band-pass filter. With the whole cell patch-clamp technique, we have investigated the effect of temperatu...

journal_title：Journal of neurophysiology

authors： Smotherman MS,Narins PM

更新日期：1998-01-01 00:00:00

abstract：:Hypocretin-1 and -2 (Hcrt-1 and -2, also called orexin-A and -B) are newly identified neuropeptides synthesized by hypothalamic neurons. Defects in the Hcrt system underlie the sleep disorder narcolepsy, which is characterized by sleep fragmentation and the involuntary loss of muscle tone called cataplexy. Hcrt neuron...

journal_title：Journal of neurophysiology

authors： Peever JH,Lai YY,Siegel JM

更新日期：2003-05-01 00:00:00