Preserved high-centrality hubs but efficient network reorganization during eyes-open state compared with eyes-closed resting state: an MEG study.

abstract：:Saccadic eye movements of different sizes and directions are represented in an orderly topographic map across the intermediate and deep layers of the superior colliculus (SC), where large saccades are encoded caudally and small saccades rostrally. Based on experiments in the cat, it has been suggested that saccades ar...

journal_title：Journal of neurophysiology

authors： Soetedjo R,Kaneko CR,Fuchs AF

更新日期：2002-06-01 00:00:00

abstract：:Anabolic-androgenic steroids (AAS) have become significant drugs of abuse in recent years with the highest increase reported in adolescent girls. In spite of the increased use of AAS, the CNS effects of these steroids are poorly understood. We report that in prepubertal female rats, three commonly abused AAS, 17alpha-...

journal_title：Journal of neurophysiology

authors： Jorge-Rivera JC,McIntyre KL,Henderson LP

更新日期：2000-06-01 00:00:00

abstract：:N-methyl-d-aspartate (NMDA) receptors play crucial roles in glutamate-mediated synaptic transmission and plasticity and are involved in a variety of brain functions. Specific single nucleotide polymorphisms (SNPs) in the genes encoding NMDA receptor subunits have been associated with some neuropsychiatric disorders in...

journal_title：Journal of neurophysiology

authors： Mori F,Ribolsi M,Kusayanagi H,Siracusano A,Mantovani V,Marasco E,Bernardi G,Centonze D

更新日期：2011-10-01 00:00:00

abstract：:The mechanism(s) of olfactory transduction in invertebrates remains to be fully understood. In lobster olfactory receptor neurons (ORNs), a nonselective sodium-gated cation (SGC) channel, a presumptive transient receptor potential (TRP)C channel homolog, plays a crucial role in olfactory transduction, at least in part...

journal_title：Journal of neurophysiology

authors： Pezier A,Bobkov YV,Ache BW

更新日期：2009-03-01 00:00:00

abstract：:There is a great need to develop new approaches for rehabilitation of the upper limb after stroke. Robotic therapy is a promising form of neurorehabilitation that can be delivered in higher doses than conventional therapy. Here we sought to determine whether the reported effects of robotic therapy, which have been bas...

journal_title：Journal of neurophysiology

authors： Kitago T,Goldsmith J,Harran M,Kane L,Berard J,Huang S,Ryan SL,Mazzoni P,Krakauer JW,Huang VS

更新日期：2015-09-01 00:00:00

abstract：:The study of quadrupeds has furnished most of our understanding of mammalian locomotion. To allow a more direct comparison of coordination between the four limbs in humans and quadrupeds, we studied crawling in the human, a behavior that is part of normal human development and mechanically more similar to quadrupedal ...

journal_title：Journal of neurophysiology

authors： Patrick SK,Noah JA,Yang JF

更新日期：2009-02-01 00:00:00

abstract：:Whenever the eyes move, spatial attention must keep track of the locations of targets as they shift on the retina. This study investigated transsaccadic updating of visual attention to cued targets. While observers prepared a saccade, we flashed an irrelevant, but salient, color cue in their visual periphery and measu...

journal_title：Journal of neurophysiology

authors： Jonikaitis D,Szinte M,Rolfs M,Cavanagh P

更新日期：2013-03-01 00:00:00

abstract：:Rodents shift their nose from side to side when they actively explore and lateralize odors in the space. This motor action is driven by a pair of muscles, the deflector nasi. We studied the premotor control of this motion. We used replication-competent rabies virus to transsynaptically label inputs to the deflector na...

journal_title：Journal of neurophysiology

authors： Kurnikova A,Deschênes M,Kleinfeld D

更新日期：2019-01-01 00:00:00

abstract：:Seizures may cause brain damage due to mechanisms initiated by excessive excitatory synaptic transmission. One such mechanism is the activation of death-promoting intracellular cascades by the influx and the perturbed homeostasis of Ca2+. The neuroprotective effects of preventing the entry of Ca2+ from voltage-depende...

journal_title：Journal of neurophysiology

authors： Pelletier MR,Wadia JS,Mills LR,Carlen PL

更新日期：1999-06-01 00:00:00

abstract：:Three nonspiking interneurons are described in this paper that influence the activity of the motor neurons of three muscles of the proximal leg joints of the stick insect. Interneurons were recorded and stained intracellularly by glass microelectrodes; motor neurons were recorded extracellularly with oil-hook electrod...

journal_title：Journal of neurophysiology

authors： Brunn DE

更新日期：1998-06-01 00:00:00

abstract：:The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparations provide an unparalleled opportunity to observe and control neural circuits. To investigate how neural circuits produce behavior, these m...

journal_title：Journal of neurophysiology

authors： Sanders JI,Kepecs A

更新日期：2012-12-01 00:00:00

abstract：:1. Semicircular-canal afferents in the squirrel monkey were characterized by their resting discharge, discharge regularity, sensitivity to galvanic currents delivered to the ear (beta *), the gain (g2Hz), and phase lead (phi 2Hz) of their response to 2-Hz sinusoidal head rotations, and their antidromic conduction velo...

journal_title：Journal of neurophysiology

authors： Lysakowski A,Minor LB,Fernández C,Goldberg JM

更新日期：1995-03-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) are known to regulate axonal refinement and dendritic branching. However, because NMDARs are abundantly present as tri-heteromers (e.g., NR1/NR2A/NR2B) during development, the precise role of the individual subunits NR2A and NR2B in these processes has not been elucidated. Ventr...

journal_title：Journal of neurophysiology

authors： Sepulveda FJ,Bustos FJ,Inostroza E,Zúñiga FA,Neve RL,Montecino M,van Zundert B

更新日期：2010-04-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) play an important role in cell survival versus cell death decisions during neuronal development, ischemia, trauma, and epilepsy. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all these conditions. In the developing CN...

journal_title：Journal of neurophysiology

authors： Wang Y,Denisova JV,Kang KS,Fontes JD,Zhu BT,Belousov AB

更新日期：2010-12-01 00:00:00

abstract：:Our perception of the positions of objects in our surroundings is surprisingly unaffected by movements of the eyes, head, and body. This suggests that the brain has a mechanism for maintaining perceptual stability, based either on the spatial relationships among visible objects or internal copies of its own motor comm...

journal_title：Journal of neurophysiology

authors： Churan J,Guitton D,Pack CC

更新日期：2011-10-01 00:00:00

abstract：:1. Pulse inputs (similar to tendon jerks) were applied to the human ankle joint with the use of a hydraulic actuator. Inputs of only 1-2 degrees could elicit large responses (> 20% of maximum voluntary contraction). The magnitude of the response depended nonlinearly on a number of factors: the amplitude, direction, an...

journal_title：Journal of neurophysiology

authors： Stein RB,Kearney RE

更新日期：1995-01-01 00:00:00

abstract：:1. A quantal analysis of transmission at the identified molluscan synapse, V2-RPr1, was performed during development. The study was intended to determine the pre- and postsynaptic contributions to the marked changes in transmitter release described in the previous report. 2. The success of the quantal analysis was pre...

journal_title：Journal of neurophysiology

authors： Pawson PA,Chase R

更新日期：1988-12-01 00:00:00

abstract：:The vestibuloocular reflex (VOR) needs to modulate its gain depending on target distance to prevent retinal slip during head movements. We investigated gain modulation (context compensation) for binocular gaze stabilization in human subjects during voluntary yaw and pitch head rotations. Movements of each eye were rec...

journal_title：Journal of neurophysiology

authors： Medendorp WP,Van Gisbergen JA,Van Pelt S,Gielen CC

更新日期：2000-12-01 00:00:00

abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...

journal_title：Journal of neurophysiology

authors： Valeyev AY,Hackman JC,Holohean AM,Wood PM,Katz JL,Davidoff RA

更新日期：1999-07-01 00:00:00

abstract：:The role of potassium channels in regulating spontaneous firing and sound-evoked responses in the central nucleus of the inferior colliculus was studied by recording single-unit activity before and during iontophoretic application of a nonspecific potassium channel blocker, tetraethylammonium (TEA). Tone bursts and si...

journal_title：Journal of neurophysiology

authors： Zhang H,Wu SH,Kelly JB

更新日期：2004-05-01 00:00:00

abstract：:High-frequency activity produces transient depression at many synapses but also, as recently demonstrated, may accelerate the recovery from use-dependent depression. We have examined the possible consequences of this synaptic mechanism in neocortical excitatory synapses by recording simultaneously from presynaptic pyr...

journal_title：Journal of neurophysiology

authors： Galarreta M,Hestrin S

更新日期：2000-01-01 00:00:00

abstract：:Primary motor cortex has been studied for more than a century, yet a consensus on its functional contribution to movement control is still out of reach. In particular, there remains controversy as to the level of control produced by motor cortex ("low-level" movement dynamics vs. "high-level" movement kinematics) and ...

journal_title：Journal of neurophysiology

authors： Omrani M,Kaufman MT,Hatsopoulos NG,Cheney PD

更新日期：2017-09-01 00:00:00

abstract：:The preceding study demonstrated that normal subjects compensate for the additional interaction torques generated when a reaching movement is made during voluntary trunk rotation. The present paper assesses the influence of trunk rotation on finger trajectories and on interjoint coordination and determines whether sim...

journal_title：Journal of neurophysiology

authors： Pigeon P,Bortolami SB,DiZio P,Lackner JR

更新日期：2003-01-01 00:00:00

abstract：:Behavioral studies have shown that object recognition becomes severely impaired at fast presentation rates, indicating a limitation in temporal processing capacity. Here, we studied whether this behavioral limit in object recognition reflects limitations in the temporal processing capacity of early visual areas tuned ...

journal_title：Journal of neurophysiology

authors： McKeeff TJ,Remus DA,Tong F

更新日期：2007-07-01 00:00:00

abstract：:Many critically ill patients in intensive care units suffer from an infection-induced whole body inflammatory state known as sepsis, which causes severe weakness in patients who survive. The mechanisms by which sepsis triggers intensive care unit-acquired weakness (ICUAW) remain unclear. Currently, research into ICUAW...

journal_title：Journal of neurophysiology

authors： Nardelli P,Khan J,Powers R,Cope TC,Rich MM

更新日期：2013-04-01 00:00:00

abstract：:Using whole cell patch-clamp recordings, we examined the effect of colchicine, a microtubule disrupter, on the properties of glycine receptors (GlyRs) in cultured spinal cord neurons. Confocal microscopy revealed that colchicine treatment effectively altered microtubule bundles and neuronal morphology. Application of ...

journal_title：Journal of neurophysiology

authors： van Zundert B,Alvarez FJ,Yevenes GE,Cárcamo JG,Vera JC,Aguayo LG

更新日期：2002-01-01 00:00:00

abstract：:Persistent inward currents are important to motoneuron excitability and firing behaviors and also have been implicated in excitotoxicity. In particular, L-type Ca2+ channels, usually located on motoneuron dendrites, play a primary role in amplification of synaptic inputs. However, recent experimental findings on L-typ...

journal_title：Journal of neurophysiology

authors： Mousa MH,Elbasiouny SM

更新日期：2020-10-01 00:00:00

abstract：:1. We studied the effect of zinc on the gamma-aminobutyric acid-C (GABAC) receptor in acutely isolated catfish cone horizontal cells using the whole cell patch-clamp technique. 2. GABA activates the GABAC receptor with a half-activation concentration (EC50) of 2.99 microM. The Hill coefficient is 1.32. Desensitization...

journal_title：Journal of neurophysiology

authors： Dong CJ,Werblin FS

更新日期：1995-02-01 00:00:00

abstract：:To localize objects relative to ourselves, we need to combine various sensory and motor signals. When these signals change abruptly, as information about eye orientation does during saccades, small differences in latency between the signals could introduce localization errors. We examine whether independent temporal i...

journal_title：Journal of neurophysiology

authors： Maij F,Brenner E,Smeets JB

更新日期：2009-07-01 00:00:00

abstract：:Neurons in the medial superior olive (MSO) are tuned to the interaural time difference (ITD) of sound arriving at the two ears. MSO neurons evoke a strongest response at their best delay (BD), at which the internal delay between bilateral inputs to MSO matches the external ITD. We performed extracellular recordings in...

journal_title：Journal of neurophysiology

authors： Day ML,Semple MN

更新日期：2011-10-01 00:00:00