Neck muscle spindle activity in the decerebrate, unparalyzed cat: dynamics and influence of vestibular stimulation.

abstract：:We investigated a visuomotor mechanism contributing to reach correction: the manual following response (MFR), which is a quick response to background visual motion that frequently occurs as a reafference when the body moves. Although several visual specificities of the MFR have been elucidated, the functional and comp...

journal_title：Journal of neurophysiology

authors： Abekawa N,Gomi H

更新日期：2010-05-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by profound deficits in memory and cognitive function. Neuropathological hallmarks of the disease include a loss of basal forebrain cholinergic neurons and the deposition of beta-amyloid peptide (Abeta) in neuritic plaques. At a cellul...

journal_title：Journal of neurophysiology

authors： Fu W,Jhamandas JH

更新日期：2003-11-01 00:00:00

abstract：:Sensorineural hearing loss (SNHL) causes an overall deficit in binaural hearing, including the abilities to localize sound sources, discriminate interaural time and level differences (ITDs and ILDs, respectively), and utilize binaural cues to aid signal detection and comprehension in noisy environments. Few studies ha...

journal_title：Journal of neurophysiology

authors： Haragopal H,Dorkoski R,Pollard AR,Whaley GA,Wohl TR,Stroud NC,Day ML

更新日期：2020-10-01 00:00:00

abstract：:1. Surgically resected tissue from the tip of the human temporal lobe of seven patients undergoing temporal lobectomy was employed to study functional properties of GABAergic inhibition mediated through activation of GABAA receptors, using patch-clamp recording techniques in acutely isolated neurons and in slices of h...

journal_title：Journal of neurophysiology

authors： Gibbs JW 3rd,Zhang YF,Kao CQ,Holloway KL,Oh KS,Coulter DA

更新日期：1996-04-01 00:00:00

abstract：:1. Intracellular recordings were made in 427 phrenic motoneurons from kittens (in four stages of postnatal development, ranging from 2 to 14 wk) and in 72 motoneurons from adult cats. These experiments were performed to determine how the pattern of spontaneous discharge changes in phrenic motoneurons during developmen...

journal_title：Journal of neurophysiology

authors： Cameron WE,Jodkowski JS,Fang H,Guthrie RD

更新日期：1991-03-01 00:00:00

abstract：:Macaque SEF neurons encode object-centered directions of eye movements regardless of the visual attributes of instructional cues. Neurons in the supplementary eye field (SEF) of the macaque monkey exhibit object-centered direction selectivity in the context of a task in which a spot flashed on the right or left end of...

journal_title：Journal of neurophysiology

authors： Olson CR,Gettner SN

更新日期：1999-05-01 00:00:00

abstract：:1. Subdivided portions of the cut ventral root innervation of the soleus muscle were electrically stimulated in 14 anesthetized cats. The stimulus trains imposed on these nerves simulated the recruitment and rate-modulation patterns of single motor units recorded during stretch-reflex responses in decerebrate preparat...

journal_title：Journal of neurophysiology

authors： Cordo PJ,Rymer WZ

更新日期：1982-05-01 00:00:00

abstract：:Visual and motor properties of single neurons of monkey ventral premotor cortex (area F5) were studied in a behavioral paradigm consisting of four conditions: object grasping in light, object grasping in dark, object fixation, and fixation of a spot of light. The employed objects were six different three-dimensional (...

journal_title：Journal of neurophysiology

authors： Murata A,Fadiga L,Fogassi L,Gallese V,Raos V,Rizzolatti G

更新日期：1997-10-01 00:00:00

abstract：:Single-electrode voltage-clamp techniques and bath application of the N-methyl-D-aspartate (NMDA) receptor antagonist 2-amino-5-phosphonovaleric acid (APV) were used to study the time course of seizure-induced alterations in NMDA-dependent synaptic currents in granule cells of the dentate gyrus in hippocampal slices f...

journal_title：Journal of neurophysiology

authors： Sayin,Rutecki P,Sutula T

更新日期：1999-02-01 00:00:00

abstract：:The cortical N1 response to balance perturbation is observed in electroencephalography recordings simultaneous to automatic balance-correcting muscle activity. We recently observed larger cortical N1s in individuals who had greater difficulty resisting compensatory steps, suggesting the N1 may be influenced by steppin...

journal_title：Journal of neurophysiology

authors： Payne AM,Ting LH

更新日期：2020-12-01 00:00:00

abstract：:1. Three parallel maps of the distribution of tuberous electroreceptor inputs are found in the medullary electrosensory lateral line lobe (ELL) of weakly electric fish. Pyramidal cells in each map are known to respond differentially to the frequency of amplitude modulations (AMs) of external electric fields in vivo. W...

journal_title：Journal of neurophysiology

authors： Turner RW,Plant JR,Maler L

更新日期：1996-10-01 00:00:00

abstract：:1. Adaptation and disadaptation rates determine the temporal response properties of sensory receptor cells. In chemoreception, temporal filter properties of receptor cells are poorly understood. We studied the time course of disadaptation in lobster antennular chemoreceptor cells by using in situ high-resolution stimu...

journal_title：Journal of neurophysiology

authors： Gomez G,Atema J

更新日期：1996-08-01 00:00:00

abstract：:The locus coeruleus (LC) noradrenergic (NE) neuromodulatory system is critically involved in regulation of neural excitability via its diffuse ascending projections. Tonic NE release in the forebrain is essential for maintenance of vigilant states and increases the signal-to-noise ratio of cortical sensory responses. ...

journal_title：Journal of neurophysiology

authors： Neves RM,van Keulen S,Yang M,Logothetis NK,Eschenko O

更新日期：2018-03-01 00:00:00

abstract：:Spinal cord neuronal circuits generate motor neuron activity patterns responsible for rhythmic hindlimb behaviors such as scratching and swimming. Kinematic analyses of limb movements generated by this motor neuron output reveal important characteristics of these behaviors. Intralimb kinematics of the turtle hindlimb ...

journal_title：Journal of neurophysiology

authors： Field EC,Stein PS

更新日期：1997-09-01 00:00:00

abstract：:Systemic exposure to N-methyl-d-aspartate (NMDA) receptor antagonists can lead to psychosis and prefrontal cortex (PFC)-dependent behavioral impairments. Agonists of metabotropic glutamate 2/3 (mGlu2/3) receptors ameliorate the adverse behavioral effects of NMDA antagonists in humans and laboratory animals, and are be...

journal_title：Journal of neurophysiology

authors： Homayoun H,Jackson ME,Moghaddam B

更新日期：2005-04-01 00:00:00

abstract：:1. Whole-cell recordings were performed on acutely isolated pyramidal neurons from rat sensorimotor cortex 2 to 21 days postnatal to study the expression of a tetrodotoxin (TTX) sensitive, voltage dependent, persistent Na+ current (INaP) during different stages of postnatal development. 2. INaP was activated positive ...

journal_title：Journal of neurophysiology

authors： Alzheimer C,Schwindt PC,Crill WE

更新日期：1993-01-01 00:00:00

abstract：:1. Less than two segments of the cervical spinal cord of the mudpuppy (Necturus maculatus) is sufficient to generate a locomotor rhythm with application of N-methyl-D-aspartic acid (NMDA). We have recorded intracellularly from rhythmically active interneurons in these segments and classified them according to their ph...

journal_title：Journal of neurophysiology

authors： Wheatley M,Jovanović K,Stein RB,Lawson V

更新日期：1994-06-01 00:00:00

abstract：:1. The responses of a total of 70 single neurons were recorded from the parabrachial nuclei (PBN) in awake rats. In 59 neurons, sapid stimuli (0.5 ml) elicited significant taste responses. Of these 59 neurons, 10 also had significant responses to water. The mean spontaneous rate of the taste neurons was 13.4 +/- 6.9 (...

journal_title：Journal of neurophysiology

authors： Nishijo H,Norgren R

更新日期：1990-04-01 00:00:00

abstract：:The aim of this study was to determine whether neuronal activity in the macaque supplementary eye field (SEF) is influenced by the rule used for saccadic target selection. Two monkeys were trained to perform a variant of the memory-guided saccade task in which any of four visible dots (rightward, upward, leftward, and...

journal_title：Journal of neurophysiology

authors： Olson CR,Gettner SN,Ventura V,Carta R,Kass RE

更新日期：2000-09-01 00:00:00

abstract：:In developing ciliary ganglion (CG) neurons, movement of functional large-conductance (BK type) Ca(2+)-activated K+ (K(Ca)) channels to the cell surface is stimulated by the endogenous growth factors TGF(beta)1 and beta-neuregulin-1 (NRG1). Here we show that a brief NRG1 treatment (0.5-1.5 h) mobilizes K(Ca) channels ...

journal_title：Journal of neurophysiology

authors： Chae KS,Oh KS,Dryer SE

更新日期：2005-08-01 00:00:00

abstract：:We asked if the information about stimulus motion used in a visual working-memory task is localized in space. Monkeys compared the directions of two moving random-dot stimuli, sample and test, separated by a temporal delay and reported whether the stimuli moved in the same or in different directions. By presenting the...

journal_title：Journal of neurophysiology

authors： Zaksas D,Bisley JW,Pasternak T

更新日期：2001-08-01 00:00:00

abstract：:1. Using patch-clamp methods, we show that brief prepulses to very positive voltages increase (facilitate) the amplitude of current through Ca2+ channels during a subsequent test pulse in some, but not all, dorsal root ganglion (DRG) sensory neurons. The amplitude of this facilitated current generally increases when t...

journal_title：Journal of neurophysiology

authors： Womack MD,McCleskey EW

更新日期：1995-05-01 00:00:00

abstract：:Although studies of the principal tongue protrudor muscle genioglossus (GG) suggest that whole muscle GG electromyographic (EMG) activities are preserved in nonrapid eye movement (NREM) sleep, it is unclear what influence sleep exerts on individual GG motor unit (MU) activities. We characterized the firing patterns of...

journal_title：Journal of neurophysiology

authors： Bailey EF,Fridel KW,Rice AD

更新日期：2007-12-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:The discharge of muscle spindle afferents from monkey spindle afferents from monkey jaw-closing muscles was studied during mastication of natural foods by extracellular recording from the fibers or cell bodies of the tract and mesencephalic nucleus of the fifth nerve. In all, 39 muscle afferents were studied. The spin...

journal_title：Journal of neurophysiology

authors： Goodwin GM,Luschei ES

更新日期：1975-05-01 00:00:00

abstract：:These experiments were designed to test the hypothesis that climbing fiber inputs evoked by a peripheral stimulus increase the responsiveness of Purkinje cells to mossy fiber inputs. This hypothesis was based on a previous series of observations demonstrating that spontaneous climbing fiber inputs are associated with ...

journal_title：Journal of neurophysiology

authors： Ebner TJ,Yu QX,Bloedel JR

更新日期：1983-07-01 00:00:00

abstract：:Voltage-gated Na+ channels (VGSC) are transmembrane proteins that are essential for the initiation and propagation of action potentials in neuronal excitability. Because neurons express a mixture of Na+ channel isoforms and protein kinase C (PKC) isozymes, the nature of which channel is being regulated by which PKC is...

journal_title：Journal of neurophysiology

authors： Vijayaragavan K,Boutjdir M,Chahine M

更新日期：2004-04-01 00:00:00

abstract：:For the first time in any vertebrate, in vivo responses of single olfactory receptor neurons to odorant mixtures were studied quantitatively. Extracellular electrophysiological response of 54 single olfactory receptor neurons from 23 channel catfish, Ictalurus punctatus, to binary mixtures of amino acids and to their ...

journal_title：Journal of neurophysiology

authors： Kang J,Caprio J

更新日期：1997-01-01 00:00:00

abstract：:1. Eleven adult cats were trained to stop inspiration in response to a conditioning stimulus. The conditioning stimuli were presented at the onset of inspiration at intervals of approximately 20-30 s. Intratracheal pressures, diaphragmatic activity, and the extracellular activity of single medullary respiratory neuron...

journal_title：Journal of neurophysiology

authors： Orem J

更新日期：1989-11-01 00:00:00

abstract：:The discovery that spontaneous fluctuations in blood oxygen level-dependent (BOLD) signals contain information about the functional organization of the brain has caused a paradigm shift in neuroimaging. It is now well established that intrinsic brain activity is organized into spatially segregated resting-state networ...

journal_title：Journal of neurophysiology

authors： Mitra A,Snyder AZ,Hacker CD,Raichle ME

更新日期：2014-06-01 00:00:00