Novel potassium channel blocker, 4-AP-3-MeOH, inhibits fast potassium channels and restores axonal conduction in injured guinea pig spinal cord white matter.

abstract：:The amygdala plays a crucial role in evaluating the emotional significance of stimuli and in transforming the results of this evaluation into appropriate autonomic responses. Lesion and stimulation studies suggest involvement of the amygdala in the generation of the skin conductance response (SCR), which is an indirec...

journal_title：Journal of neurophysiology

authors： Laine CM,Spitler KM,Mosher CP,Gothard KM

更新日期：2009-04-01 00:00:00

abstract：:1. Experimental measures of input resistance, RN, and responses to brief hyperpolarizing current pulses were obtained in identified gamma-motoneurons in pentobarbital-anesthetized cats using conventional sharp micropipettes. The same cells were subsequently injected with horseradish peroxidase and completely reconstru...

journal_title：Journal of neurophysiology

authors： Burke RE,Fyffe RE,Moschovakis AK

更新日期：1994-11-01 00:00:00

abstract：:1. We present a new mathematical description of the complete distribution of electrical responses to stochastic synaptic activity (quantal analysis) that is intended as a model of experiments on central neuronal synapses. Unlike previous treatments, this distribution is calculated for each instant after the release of...

journal_title：Journal of neurophysiology

authors： Blum KI,Idiart MA

更新日期：1994-09-01 00:00:00

abstract：:1. Intracellular recordings were made from layer VI pyramidal cells in in vitro slice preparations of the cat motor cortex (area 4 gamma). Layer VI pyramidal cells were identified morphologically by intracellular injection of biocytin. 2. Of 22 layer VI pyramidal cells examined, single action potentials were followed ...

journal_title：Journal of neurophysiology

authors： Kang Y,Kayano F

更新日期：1994-08-01 00:00:00

abstract：:1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied...

journal_title：Journal of neurophysiology

authors： Breakwell NA,Rowan MJ,Anwyl R

更新日期：1996-11-01 00:00:00

abstract：:Swimming behavior in the marine mollusc Tritonia diomedea is episodic, consisting of a series of alternating dorsal and ventral flexions initiated by a brief sensory stimulus. The swim motor pattern is generated by a network formed of four groups of premotor interneurons: cerebral cell 2 (C2), dorsal swim interneurons...

journal_title：Journal of neurophysiology

authors： Getting PA,Dekin MS

更新日期：1985-02-01 00:00:00

abstract：:The corticospinal tract excitability is modulated when preparing movements. Earlier to movement execution, the excitability of the spinal cord increases waiting for supraspinal commands to release the movement. Movement execution and movement observation share processes within the motor system, although movement obser...

journal_title：Journal of neurophysiology

authors： Arias P,Robles-García V,Espinosa N,Corral-Bergantiños Y,Mordillo-Mateos L,Grieve K,Oliviero A,Cudeiro J

更新日期：2014-04-01 00:00:00

abstract：:Chronic pain after nerve injury is often accompanied by hypersensitivity to mechanical stimuli, yet whether this reflects altered input, altered processing, or both remains unclear. Spinal nerve ligation or transection results in hypersensitivity to mechanical stimuli in skin innervated by adjacent dorsal root ganglia...

journal_title：Journal of neurophysiology

authors： Boada MD,Gutierrez S,Aschenbrenner CA,Houle TT,Hayashida K,Ririe DG,Eisenach JC

更新日期：2015-01-01 00:00:00

abstract：:The movement representation in the primary motor cortex (M1) of the cat develops between postnatal weeks 7-12. The somatosensory representation in motor cortex is present by the age that the motor map begins to develop. In this study we examined the role of neural activity in development and maintenance of the M1 move...

journal_title：Journal of neurophysiology

authors： Chakrabarty S,Martin JH

更新日期：2005-11-01 00:00:00

abstract：:The locus coeruleus (LC) noradrenergic (NE) neuromodulatory system is critically involved in regulation of neural excitability via its diffuse ascending projections. Tonic NE release in the forebrain is essential for maintenance of vigilant states and increases the signal-to-noise ratio of cortical sensory responses. ...

journal_title：Journal of neurophysiology

authors： Neves RM,van Keulen S,Yang M,Logothetis NK,Eschenko O

更新日期：2018-03-01 00:00:00

abstract：:We investigated a visuomotor mechanism contributing to reach correction: the manual following response (MFR), which is a quick response to background visual motion that frequently occurs as a reafference when the body moves. Although several visual specificities of the MFR have been elucidated, the functional and comp...

journal_title：Journal of neurophysiology

authors： Abekawa N,Gomi H

更新日期：2010-05-01 00:00:00

abstract：:We studied the effects of fatigue of the index finger on indices of force variability in discrete and rhythmic accurate force production tasks performed by the index finger and by all four fingers pressing in parallel. An increase in the variance of the force produced by the fatigued index finger was expected. We hypo...

journal_title：Journal of neurophysiology

authors： Singh T,Varadhan SK,Zatsiorsky VM,Latash ML

更新日期：2010-06-01 00:00:00

abstract：:1. We used period/amplitude (PA) analysis to survey electroencephalography (EEG) across vigilance states in the Sprague-Dawley rat. We found a fast cortical EEG frequency band, which we designate rho, whose wave amplitude in rapid eye movement (REM) was elevated above the levels in both waking and nonrapid eye movemen...

journal_title：Journal of neurophysiology

authors： Campbell IG,Feinberg I

更新日期：1993-04-01 00:00:00

abstract：:This study determined the effect of mixed (slip- and trip-like stance perturbation) training on reactive responses in people with chronic stroke (PwCS) and examined modulation of their reactive responses on higher intensity perturbations posttraining (scaling). Twelve PwCS were exposed to consecutive blocks of treadmi...

journal_title：Journal of neurophysiology

authors： Dusane S,Bhatt T

更新日期：2020-07-01 00:00:00

abstract：:Spatiotemporal patterns of dorsal root-evoked potentials were studied in transverse slices of the rat spinal cord by monitoring optical signals from a voltage-sensitive dye with multiple-photodiode optic camera. Typically, dorsal root stimulation generated two basic waveforms of voltage images: dual-component images c...

journal_title：Journal of neurophysiology

authors： Ziskind-Conhaim L,Redman S

更新日期：2005-09-01 00:00:00

abstract：:Successful motor performance relies on our ability to adapt to changes in the environment by learning novel mappings between motor commands and sensory outcomes. Such adaptation is thought to involve two distinct mechanisms: an implicit, error-based component linked to slow learning and an explicit, strategic componen...

journal_title：Journal of neurophysiology

authors： de Brouwer AJ,Albaghdadi M,Flanagan JR,Gallivan JP

更新日期：2018-10-01 00:00:00

abstract：:Synaptic transmission at the inner hair cell (IHC) afferent synapse, the first synapse in the auditory pathway, is specialized for rapid and reliable signaling. Here we investigated the properties of a hyperpolarization-activated current (I(h)), expressed in the afferent dendrite of auditory nerve fibers, and its role...

journal_title：Journal of neurophysiology

authors： Yi E,Roux I,Glowatzki E

更新日期：2010-05-01 00:00:00

abstract：:Cholinergic signaling coupled to sensory-driven neuronal depolarization is essential for modulating lasting changes in deep-layer neural excitability and experience-dependent plasticity in the primary auditory cortex. However, the underlying cellular mechanism(s) associated with coincident cholinergic receptor activat...

journal_title：Journal of neurophysiology

authors： Fu X,Ye H,Jia H,Wang X,Chomiak T,Luo F

更新日期：2019-12-01 00:00:00

abstract：:We examined the activity of neurons in the lateral intraparietal area (LIP) during a task in which we measured attention in the monkey, using an advantage in contrast sensitivity as our definition of attention. The animals planned a memory-guided saccade but made or canceled it depending on the orientation of a briefl...

journal_title：Journal of neurophysiology

authors： Bisley JW,Goldberg ME

更新日期：2006-03-01 00:00:00

abstract：:The inhibitory circuits of the striatum are known to be critical for motor function, yet their contributions to Parkinsonian motor deficits are not clear. Altered firing in the globus pallidus suggests that striatal medium spiny neurons (MSN) of the direct (D1 MSN) and indirect pathway (D2 MSN) are imbalanced during d...

journal_title：Journal of neurophysiology

authors： Damodaran S,Evans RC,Blackwell KT

更新日期：2014-02-01 00:00:00

abstract：:Plasticity at the neuronal level commonly involves use-dependent changes in strength of particular synaptic pathways or regulation of postsynaptic properties by modulatory transmitters. Here we analyze a novel form of short-term plasticity mediated by use-dependent facilitation of postsynaptic responsiveness. Using cu...

journal_title：Journal of neurophysiology

authors： Svirskis G,Hounsgaard J

更新日期：1997-09-01 00:00:00

abstract：:Fear conditioning studies have led to the view that the amygdala contains neurons that signal threat and in turn elicit defensive behaviors through their brain stem and hypothalamic targets. In agreement with this model, a prior unit-recording study in rats performing a seminaturalistic foraging task revealed that man...

journal_title：Journal of neurophysiology

authors： Amir A,Kyriazi P,Lee SC,Headley DB,Paré D

更新日期：2019-05-01 00:00:00

abstract：:Response adaptation is the change of the firing rate of neurons induced by a preceding stimulus. It can be found in many sensory systems and throughout the auditory pathway. We investigated response adaptation in the external nucleus of the inferior colliculus (ICX) of barn owls ( Tyto furcata), a nocturnal bird of pr...

journal_title：Journal of neurophysiology

authors： Ferger R,Pawlowsky K,Singheiser M,Wagner H

更新日期：2018-03-01 00:00:00

abstract：:A stratified organization of visual, somatic and acoustic representations was observed in the cat SC. Cells of the superficial laminae were exclusively visual. Visual, somatic, and acoustic cells were observed in the intermediate laminae while the deeper laminae were predominantly nonvisual. A detailed examination of ...

journal_title：Journal of neurophysiology

authors： Stein BE,Magalhães-Castro B,Kruger L

更新日期：1976-03-01 00:00:00

abstract：:A popular theory is that the cerebellum functions as a timer for clocking motor events (e.g., initiation, termination). Consistent with this idea, cerebellar patients have been reported to show greater deficits during hand movements that repeatedly start and stop (i.e., discontinuous movements) compared with continuou...

journal_title：Journal of neurophysiology

authors： Bo J,Block HJ,Clark JE,Bastian AJ

更新日期：2008-11-01 00:00:00

abstract：:The hearing ability of five Japanese macaques (Macaca fuscata) was assessed following two-stage bilateral auditory cortex lesions. The animals were tested using a shock-avoidance procedure with a conditioned-suppression procedure used for comparison in two cases. The animals initially were unable to respond to sound, ...

journal_title：Journal of neurophysiology

authors： Heffner HE,Heffner RS

更新日期：1986-02-01 00:00:00

abstract：:The functional significance of vestibular information for the generation of gaze shifts is controversial and less well established than the vestibular contribution to gaze stability. In this study, we asked seven bilaterally avestibular patients to execute voluntary, whole body pivot turns to visual targets up to 180°...

journal_title：Journal of neurophysiology

authors： Anastasopoulos D,Ziavra N,Bronstein AM

更新日期：2019-11-01 00:00:00

abstract：:We constantly make eye movements to bring objects of interest onto the fovea for more detailed processing. Activity in area V4, a prestriate visual area, is enhanced at the location corresponding to the target of an eye movement. However, the precise role of activity in V4 in relation to these saccades and the modulat...

journal_title：Journal of neurophysiology

authors： Gee AL,Ipata AE,Goldberg ME

更新日期：2010-10-01 00:00:00

abstract：:The noted disruption of thalamocortical connections and abnormalities in tactile sensory function has resulted in a new definition of cerebral palsy (CP) that recognizes the sensorimotor integration process as central to the motor impairments seen in these children. Despite this updated definition, the connection betw...

journal_title：Journal of neurophysiology

authors： Kurz MJ,Heinrichs-Graham E,Becker KM,Wilson TW

更新日期：2015-05-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00