Hearing loss in Japanese macaques following bilateral auditory cortex lesions.

abstract：:Odor responses of neocortical neurons in rabbits under light pentobarbital anesthesia were studied in a restricted area in the lateral half of the prefrontal cortex close to the frontal pole. A preevent cumulative sum chart provided a visual display of the change in unit discharge rate following each odor stimulation,...

journal_title：Journal of neurophysiology

authors： Onoda N,Imamura K,Obata E,Iino M

更新日期：1984-10-01 00:00:00

abstract：:To trigger action potentials in neurons, most investigators use electrical or chemical stimulation. Here we describe an optical stimulation method based on semi-synthetic light-activated ion channels. These SPARK (synthetic photoisomerizable azobenzene-regulated K(+)) channels consist of a synthetic azobenzene-contain...

journal_title：Journal of neurophysiology

authors： Chambers JJ,Banghart MR,Trauner D,Kramer RH

更新日期：2006-11-01 00:00:00

abstract：:The octopus cells of the posteroventral cochlear nucleus receive inputs from auditory-nerve fibers and form one of the major ascending auditory pathways. They respond to acoustic and electrical stimulation transiently and are believed to carry temporal information in the precise timing of their action potentials. The ...

journal_title：Journal of neurophysiology

authors： Cai Y,Walsh EJ,McGee J

更新日期：1997-08-01 00:00:00

abstract：:1. The actions of hydrogen sulfide (HS-) on membrane and synaptic properties of dorsal raphe (DR) serotonergic cells were studied in the in vitro brain stem slice preparation, using intracellular sharp microelectrode and whole-cell recording techniques. 2. Sulfide produced two reversible, concentration-dependent effec...

journal_title：Journal of neurophysiology

authors： Kombian SB,Reiffenstein RJ,Colmers WF

更新日期：1993-07-01 00:00:00

abstract：:In sensory systems, the thalamus has historically been considered a relay station. Neural representations of temporal modulations in the auditory system undergo considerable changes as they pass from the inferior colliculus (IC) to the auditory cortex. We sought to determine in awake primates the extent to which audit...

journal_title：Journal of neurophysiology

authors： Bartlett EL,Wang X

更新日期：2007-02-01 00:00:00

abstract：:The concept of hierarchical motor control has been viewed as a means of progressively decreasing the number of variables manipulated by each higher control level. We tested the hypothesis that turning an individual bimanual force-production task into a joint (two-participant) force-production task would lead to positi...

journal_title：Journal of neurophysiology

authors： Masumoto J,Inui N

更新日期：2015-06-01 00:00:00

abstract：:Inactivation permits direct assessment of the functional contribution of a given brain area to behavior. Previous inactivation studies of the frontal eye field (FEF) have either used large permanent ablations or reversible pharmacological techniques that only inactivate a small volume of tissue. Here we evaluated the ...

journal_title：Journal of neurophysiology

authors： Peel TR,Johnston K,Lomber SG,Corneil BD

更新日期：2014-01-01 00:00:00

abstract：:The earliest neural response to a mechanical perturbation, the short-latency stretch response (R1: 20-45 ms), is known to exhibit "automatic gain-scaling" whereby its magnitude is proportional to preperturbation muscle activity. Because gain-scaling likely reflects an intrinsic property of the motoneuron pool (via the...

journal_title：Journal of neurophysiology

authors： Pruszynski JA,Kurtzer I,Lillicrap TP,Scott SH

更新日期：2009-08-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:The marine mollusk Clione limacina, when swimming, can stabilize different body orientations in the gravitational field. The stabilization is based on the reflexes initiated by activation of the statocyst receptor cells and mediated by the cerebro-pedal interneurons that produce excitation of the motoneurons of the ef...

journal_title：Journal of neurophysiology

authors： Deliagina TG,Orlovsky GN,Selverston AI,Arshavsky YI

更新日期：2000-01-01 00:00:00

abstract：:A spherical approximation technique is presented that affords a mathematical characterization of a virtual space receptive field (VSRF) based on first-spike latency in the auditory cortex of cat. Parameterizing directional sensitivity in this fashion is much akin to the use of difference-of-Gaussian (DOG) functions fo...

journal_title：Journal of neurophysiology

authors： Jenison RL,Reale RA,Hind JE,Brugge JF

更新日期：1998-11-01 00:00:00

abstract：:The horizontal angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration rotations was studied in four squirrel monkeys after unilateral labyrinthectomy. Spontaneous nystagmus was measured at the beginning and end of each testing session. During the period that animals were kept in darkness (4 d...

journal_title：Journal of neurophysiology

authors： Lasker DM,Hullar TE,Minor LB

更新日期：2000-05-01 00:00:00

abstract：:The present study was an examination of state-dependent functional connectivity during spontaneous activity between the piriform cortex and its upstream and downstream connections. Rats were anesthetized with urethan and allowed to spontaneously cycle between fast- and slow-wave states similar to fast- and slow-wave s...

journal_title：Journal of neurophysiology

authors： Wilson DA,Yan X

更新日期：2010-12-01 00:00:00

abstract：:Patch clamp is the main technique for measuring electrical properties of individual cells. Since its discovery in 1976 by Neher and Sakmann, patch clamp has been instrumental in broadening our understanding of the fundamental properties of ion channels and synapses in neurons. The conventional patch-clamp method requi...

journal_title：Journal of neurophysiology

authors： Wu 吴秋雨 Q,Kolb I,Callahan BM,Su Z,Stoy W,Kodandaramaiah SB,Neve R,Zeng H,Boyden ES,Forest CR,Chubykin AA

更新日期：2016-10-01 00:00:00

abstract：:Local computation in microcircuits is an essential feature of distributed information processing in vertebrate and invertebrate brains. The insect antennal lobe represents a spatially confined local network that processes high-dimensional and redundant peripheral input to compute an efficient odor code. Social insects...

journal_title：Journal of neurophysiology

authors： Meyer A,Galizia CG,Nawrot MP

更新日期：2013-11-01 00:00:00

abstract：:Clinical and experimental research has demonstrated that the emotional experience of fear and anxiety impairs postural stability in humans. The current study investigated whether changes in fear and anxiety can also modulate spinal stretch reflexes and the gain of afferent inputs to the primary somatosensory cortex. T...

journal_title：Journal of neurophysiology

authors： Davis JR,Horslen BC,Nishikawa K,Fukushima K,Chua R,Inglis JT,Carpenter MG

更新日期：2011-12-01 00:00:00

abstract：:We have previously demonstrated that neurons R3-14 of the Aplysia abdominal ganglia specifically express a gene encoding a 108-amino acid neuropeptide precursor. This precursor is postranslationally processed by cleavage of a signal sequence and two internal dibasic residues resulting in three peptides. The peptide pr...

journal_title：Journal of neurophysiology

authors： Campanelli JT,Scheller RH

更新日期：1987-04-01 00:00:00

abstract：:Microsleeps are brief episodes of arousal level decrease manifested through behavioral signs. Brain activity during microsleep in the presence of external stimulus remains poorly understood. In this study, we sought to understand neural responses to auditory stimulation during microsleep. We gave participants the simp...

journal_title：Journal of neurophysiology

authors： Yong Z,Tan JH,Hsieh PJ

更新日期：2019-12-01 00:00:00

abstract：:We asked whether podokinetic adaptation to walking on a circular treadmill transfers to different forms of locomotion. Subjects were blindfolded and asked to walk straight across the floor, in the forward and backward directions, following podokinetic (PK) stimulation that consisted of 30 min of forward walking-in-pla...

journal_title：Journal of neurophysiology

authors： Earhart GM,Jones GM,Horak FB,Block EW,Weber KD,Fletcher WA

更新日期：2001-10-01 00:00:00

abstract：:An in vitro brain stem-spinal cord preparation from an adult urodele (Pleurodeles waltl) was developed in which two fictive rhythmic motor patterns were evoked by bath application of N-methyl-D-aspartate (NMDA; 2.5-10 microM) with D-serine (10 microM). Both motor patterns displayed left-right alternation. The first pa...

journal_title：Journal of neurophysiology

authors： Delvolvé I,Branchereau P,Dubuc R,Cabelguen JM

更新日期：1999-08-01 00:00:00

abstract：:1. The initial objective of this study was to determine whether respiratory-related neural assemblies exist in the brain stem midline. A second goal was to seek evidence for concurrent relationships among the neurons that could generate the detected synchrony. 2. Experiments were conducted on anesthetized, paralyzed, ...

journal_title：Journal of neurophysiology

authors： Lindsey BG,Hernandez YM,Morris KF,Shannon R,Gerstein GL

更新日期：1992-04-01 00:00:00

abstract：:Microelectrode studies in monkeys performing short-term memory tasks show the sustained elevated discharge of cortical neurons during the retention of recalled sensory information. Cortical cells that are part of memory networks are assumed to receive numerous inputs of excitatory as well as inhibitory nature and loca...

journal_title：Journal of neurophysiology

authors： Bodner M,Zhou YD,Fuster JM

更新日期：1997-04-01 00:00:00

abstract：:1. Taste buds in catfish are found not only within the oropharyngeal cavity, as in mammals, but are also located along the external body surface of the animal from the barbels and lips to the caudal fin. Because these taste buds are innervated by the facial (cranial VII) nerve, the extraoral taste system of catfish is...

journal_title：Journal of neurophysiology

authors： Michel W,Caprio J

更新日期：1991-07-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) are comprised of different subunits. NR2 subunits confer different pharmacological and biophysical properties to NMDARs. Although NR2B subunit expression is uniform throughout striatum, NR2A subunit expression is greater laterally. Pharmacologically isolated NMDAR-mediated excit...

journal_title：Journal of neurophysiology

authors： Chapman DE,Keefe KA,Wilcox KS

更新日期：2003-01-01 00:00:00

abstract：:We investigated the afferents and intracortical synaptic organization of the anterior cingulate cortex (ACC) during noxious electrical stimulation. Extracellular field potentials were recorded simultaneously from 16 electrodes spanning all layers of the ACC in male Sprague-Dawley rats anesthetized by halothane inhalat...

journal_title：Journal of neurophysiology

authors： Yang JW,Shih HC,Shyu BC

更新日期：2006-12-01 00:00:00

abstract：:1. We studied the blocking properties of a spider (Nephila clavata) toxin (JSTX) purified from venom on the spiny lobster neuromuscular junction. 2. When a small amount of JSTX was applied to the neuromuscular junction, the excitatory postsynaptic potential (EPSP) was partially suppressed. The amplitude of EPSPs remai...

journal_title：Journal of neurophysiology

authors： Miwa A,Kawai N,Saito M,Pan-Hou H,Yoshioka M

更新日期：1987-08-01 00:00:00

abstract：:The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...

journal_title：Journal of neurophysiology

authors： Stewart CE,Kanicki AC,Altschuler RA,King WM

更新日期：2018-02-01 00:00:00

abstract：:Nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of Parkinson's disease (PD). Studies in rodent and primate models have revealed that striatal projection neurons, namely, medium spiny neurons (MSNs), increase the firing frequency. However, their activity...

journal_title：Journal of neurophysiology

authors： Singh A,Liang L,Kaneoke Y,Cao X,Papa SM

更新日期：2015-03-01 00:00:00

abstract：:When sudden environmental stimuli signaling threat occur in the portion of space surrounding the body (defensive peripersonal space), defensive responses are enhanced. Recently Bisio et al. (Bisio A, Garbarini F, Biggio M, Fossataro C, Ruggeri P, Bove M. J Neurosci 37: 2415-2424, 2017) showed that a marker of defensiv...

journal_title：Journal of neurophysiology

authors： Bufacchi RJ

更新日期：2017-10-01 00:00:00

abstract：:Pathologic reorganization of spinal networks and activity-dependent plasticity are common neuronal adaptations after spinal cord injury (SCI) in humans. In this work, we examined changes of reciprocal Ia and nonreciprocal Ib inhibition after locomotor training in 16 people with chronic SCI. The soleus H-reflex depress...

journal_title：Journal of neurophysiology

authors： Knikou M,Smith AC,Mummidisetty CK

更新日期：2015-04-01 00:00:00