Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch.

abstract：:This study of chronic incomplete spinal cord injury (SCI) subjects investigated patterns of central motor drive (i.e., central activation) of the plantar flexors using interpolated twitches, and modulation of soleus H-reflexes during lengthening, isometric, and shortening muscle actions. In a recent study of the knee ...

journal_title：Journal of neurophysiology

authors： Kim HE,Corcos DM,Hornby TG

更新日期：2015-07-01 00:00:00

abstract：:Fine flexible wire microelectrodes chronically implanted in the fifth lumbar ventral root (L5 VR) of 17 cats rendered stable records of the natural discharge patterns of 164 individual axons during locomotion on a treadmill. Fifty-one out of 164 axons were identified as motoneurons projecting to the anterior thigh mus...

journal_title：Journal of neurophysiology

authors： Hoffer JA,Loeb GE,Marks WB,O'Donovan MJ,Pratt CA,Sugano N

更新日期：1987-02-01 00:00:00

abstract：:The short-term (3-51 days) and long-term (31-42 wk) effects of corpus callosum transection on the receptive-field properties of neurons were assessed at the single-cell, architectural, and topographical levels of organization in the cat striate cortex. Corpus callosum transection decreased the proportion of neurons th...

journal_title：Journal of neurophysiology

authors： Payne BR,Pearson HE,Berman N

更新日期：1984-09-01 00:00:00

abstract：:Whole cell patch-clamp recordings revealed a subpopulation (16%, n = 18/112) of rat median preoptic nucleus (MnPO) neurons responded to bath-applied angiotensin II (Ang II; 100 nM to 5 microM; 30-90 s) with a prolonged TTX-resistant membrane depolarization and rhythmic bursting activity. At rest, cells characteristica...

journal_title：Journal of neurophysiology

authors： Spanswick D,Renaud LP

更新日期：2005-04-01 00:00:00

abstract：:Visual search is a ubiquitous visual behavior, and efficient search is essential for survival. Different cognitive models have explained the speed and accuracy of search based either on the dynamics of attention or on similarity of item representations. Here, we examined the extent to which performance on a visual sea...

journal_title：Journal of neurophysiology

authors： Cohen MA,Alvarez GA,Nakayama K,Konkle T

更新日期：2017-01-01 00:00:00

abstract：:Studies on the expression and cellular function of sigma receptors in autonomic neurons were conducted in neonatal rat intracardiac and superior cervical (SCG) ganglia. Individual neurons from SCG and intracardiac ganglia were shown to express transcripts encoding the sigma-1 receptor using single-cell RT-PCR techniqu...

journal_title：Journal of neurophysiology

authors： Zhang H,Cuevas J

更新日期：2002-06-01 00:00:00

abstract：:Precise motion control is critical to human survival on Earth and in space. Motion sensation is inherently imprecise, and the functional implications of this imprecision are not well understood. We studied a "vestibular" manual control task in which subjects attempted to keep themselves upright with a rotational hand ...

journal_title：Journal of neurophysiology

authors： Rosenberg MJ,Galvan-Garza RC,Clark TK,Sherwood DP,Young LR,Karmali F

更新日期：2018-12-01 00:00:00

abstract：:To estimate contour-orientation sensitivity of the cat and the degree to which precortical processing contributes to such estimates, the amplitude of visually evoked potentials (VEP) recorded from the visual cortex of cats in response to a visual stimulus (S2) presented at various intervals after presentation of anoth...

journal_title：Journal of neurophysiology

authors： Tootle JS,Berkley MA

更新日期：1985-05-01 00:00:00

abstract：:In the absence of any obvious input, sensory neurons and interneurons can display resting or spontaneous activity. This is often regarded as noise and removed through trial averaging, although it may reflect history-dependent modulation of tuning or fidelity and, thus, be of functional relevance to downstream interneu...

journal_title：Journal of neurophysiology

authors： Lepreux G,Haupt SS,Dürr V

更新日期：2019-12-01 00:00:00

abstract：:1. Red rod photoreceptors in the toad retina, which are known to be physiologically coupled, were examined for interreceptor contacts. 2. A dense network of large gap junctions was found between the inner segments of red rods, this being the only specialized site of contact that was observed between rods. Each red rod...

journal_title：Journal of neurophysiology

authors： Gold GH,Dowling JE

更新日期：1979-01-01 00:00:00

abstract：:As a vital skill in an evolving world, interception of moving objects relies on accurate prediction of target motion. In natural circumstances, active gaze shifts often accompany hand movements when exploring targets of interest, but how eye and hand movements are coordinated during manual interception and their depen...

journal_title：Journal of neurophysiology

authors： Li Y,Wang Y,Cui H

更新日期：2018-01-01 00:00:00

abstract：:In adult songbirds, auditory neurons in the primary auditory forebrain region of field L and a secondary auditory forebrain region of caudal mesopallium (CM) are highly responsive to natural sounds, such as conspecific song. Because these nuclei are involved in sensory representations of songs, we investigated how the...

journal_title：Journal of neurophysiology

authors： Amin N,Doupe A,Theunissen FE

更新日期：2007-05-01 00:00:00

abstract：:The spinal cord has been well established as the site of generation of the locomotor rhythm in vertebrates, but studies have suggested that the caudal hindbrain in larval fish and amphibians can also generate locomotor rhythms. Here, we investigated whether the caudal hindbrain of the adult lamprey ( Petromyzon marinu...

journal_title：Journal of neurophysiology

authors： Buchanan JT

更新日期：2018-05-01 00:00:00

abstract：:1. The aims of this study were 1) to determine whether the impulse activity in rabbit aortic baroreceptors (BRs) was influenced by changes in nonpulsatile flow through the aortic lumen and 2) to examine the BR and aortic arch responses to changes in temperature. 2. An in vitro aortic arch-aortic nerve preparation was ...

journal_title：Journal of neurophysiology

authors： Munch PA

更新日期：1993-12-01 00:00:00

abstract：:The horizontal cell is a second-order retinal neuron that is depolarized in the dark and responds to light with graded potential changes. In such a nonspiking neuron, not only the voltage-gated ionic conductances but also Ca(2+) regulation mechanisms, e.g., the Na(+)/Ca(2+) exchange and the Ca(2+) pump, are considered...

journal_title：Journal of neurophysiology

authors： Hayashida Y,Yagi T

更新日期：2002-01-01 00:00:00

abstract：:Histamine is a known secretagogue in adrenal chromaffin cells. Activation of G-protein linked H(1) receptors stimulates phospholipase C, which generates inositol trisphosphate leading to release of intracellular calcium stores and stimulation of calcium influx through store operated and other channels. This calcium le...

journal_title：Journal of neurophysiology

authors： Currie KP,Fox AP

更新日期：2000-03-01 00:00:00

abstract：:The study of quadrupeds has furnished most of our understanding of mammalian locomotion. To allow a more direct comparison of coordination between the four limbs in humans and quadrupeds, we studied crawling in the human, a behavior that is part of normal human development and mechanically more similar to quadrupedal ...

journal_title：Journal of neurophysiology

authors： Patrick SK,Noah JA,Yang JF

更新日期：2009-02-01 00:00:00

abstract：:Although metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5 are often found to have similar functions, there is considerable evidence that the two receptors also serve distinct functions in neurons. In hippocampal area CA1, mGluR5 has been most strongly implicated in long-term synaptic depression (LTD), where...

journal_title：Journal of neurophysiology

authors： Volk LJ,Daly CA,Huber KM

更新日期：2006-04-01 00:00:00

abstract：:Morphine remains widely used in clinical settings due to its potent analgesic properties. However, one of the gravest risks of all opioids is their ability to induce respiratory depression and subsequent brain hypoxia that can lead to coma and death. Due to these life-threatening effects, our goal was to examine the e...

journal_title：Journal of neurophysiology

authors： Solis E Jr,Afzal A,Kiyatkin EA

更新日期：2018-11-01 00:00:00

abstract：:Spinal cord neuronal circuits generate motor neuron activity patterns responsible for rhythmic hindlimb behaviors such as scratching and swimming. Kinematic analyses of limb movements generated by this motor neuron output reveal important characteristics of these behaviors. Intralimb kinematics of the turtle hindlimb ...

journal_title：Journal of neurophysiology

authors： Field EC,Stein PS

更新日期：1997-09-01 00:00:00

abstract：:1. We describe a four-layered neural network (Fig. 1), based on the input organization of a collision signaling neuron in the visual system of the locust, the lobula giant movement detector (LGMD). The 250 photoreceptors ("P" units) in layer 1 are excited by any change in illumination, generated when an image edge pas...

journal_title：Journal of neurophysiology

authors： Rind FC,Bramwell DI

更新日期：1996-03-01 00:00:00

abstract：:Current-clamp recordings were made from the deep cerebellar nuclei (DCN) of 12- to 15-day-old rats to understand the factors that mediate intrinsic spontaneous firing patterns. All of the cells recorded were spontaneously active with spiking patterns ranging continuously from regular spiking to spontaneous bursting wi...

journal_title：Journal of neurophysiology

authors： Aizenman CD,Linden DJ

更新日期：1999-10-01 00:00:00

abstract：:In contrast to hand movements, the existence of a neural representation of saccade kinematics is unclear. Saccade kinematics is typically thought to be specified by motor error/desired displacement and generated by brain stem circuits that are not penetrable to voluntary control. We studied the influence of instructed...

journal_title：Journal of neurophysiology

authors： Gopal A,Jana S,Murthy A

更新日期：2017-09-01 00:00:00

abstract：:Previous behavioral work has shown the existence of both anticipatory and reactive grip force responses to predictable load perturbations, but how the brain implements anticipatory control remains unclear. Here we recorded electroencephalographs while participants were subjected to predictable and unpredictable extern...

journal_title：Journal of neurophysiology

authors： Kourtis D,Kwok HF,Roach N,Wing AM,Praamstra P

更新日期：2008-02-01 00:00:00

abstract：:1. The purpose of this study was to use the techniques of spike- and stimulus-triggered averaging (SpTA and StTA, respectively) to examine the output organization of individual rubromotoneuronal (RM) cells in relation to clusters of neighboring cells. SpTA of electromyographic (EMG) activity in awake monkeys reveals t...

journal_title：Journal of neurophysiology

authors： Cheney PD,Mewes K,Widener G

更新日期：1991-12-01 00:00:00

abstract：:1. The behavior of the combined eye-head gaze saccade mechanism was investigated in the rhesus monkey under both normal circumstances and in the presence of perturbations delivered to the head by a torque motor. Animals were trained to follow a target light that stepped at regular intervals through an angle of 68 degr...

journal_title：Journal of neurophysiology

authors： Tomlinson RD

更新日期：1990-12-01 00:00:00

abstract：:Calcium ions are known to play an important role in epileptogenesis. Although there is clear evidence for increased neuronal calcium influx during epileptiform potentials, direct measurements of the corresponding intracellular calcium transients are rare and the origin of calcium influx is not known. Therefore the spa...

journal_title：Journal of neurophysiology

authors： Albowitz B,König P,Kuhnt U

更新日期：1997-01-01 00:00:00

abstract：:We are studying the functional "logic" of neuromodulatory actions in a simple central pattern generator (CPG)-effector system, the heart of the blue crab Callinectes sapidus. The rhythmic contractions of this heart are neurogenic, driven by rhythmic motor patterns generated by the cardiac ganglion (CG). Here we used a...

journal_title：Journal of neurophysiology

authors： Fort TJ,Brezina V,Miller MW

更新日期：2007-11-01 00:00:00

abstract：:1. Dim backgrounds can enhance small-spot flicker responses of cat retinal horizontal cells by a factor of 2 or more. 2. Intracellular marking with horseradish peroxidase (HRP) reveals that this enhancement effect occurs in--but is not necessarily limited to--the cone-connected, A-type horizontal cell. 3. Flicker ampl...

journal_title：Journal of neurophysiology

authors： Pflug R,Nelson R,Ahnelt PK

更新日期：1990-08-01 00:00:00

abstract：:The use of chronic intracortical multielectrode arrays has become increasingly prevalent in neurophysiological experiments. However, it is not obvious whether neuronal signals obtained over multiple recording sessions come from the same or different neurons. Here, we develop a criterion to assess single-unit stability...

journal_title：Journal of neurophysiology

authors： Dickey AS,Suminski A,Amit Y,Hatsopoulos NG

更新日期：2009-08-01 00:00:00