Abstract:
:Odor responses of neocortical neurons in rabbits under light pentobarbital anesthesia were studied in a restricted area in the lateral half of the prefrontal cortex close to the frontal pole. A preevent cumulative sum chart provided a visual display of the change in unit discharge rate following each odor stimulation, and critical levels on each chart provided a visual display of statistical significance. The neocortical neurons studied were activated predominantly by biologically significant odors, such as feces, urine, and dry food. Of those same neurons, 90% failed to respond to pure-chemical odors, and no neurons were found that responded to pure-chemical odors alone. Some neurons responded exclusively to one of the animal-product odors. Some odor-sensitive neurons were affected by electrical stimulation of the mediodorsal thalamic nucleus. Responses to the animal-product odors were observed after ablation of the trigeminal and/or vomeronasal inputs. The responses to these pheromone-like substances are discussed in the context of a central role for odor-sensitive neocortical neurons in cognitive aspects of discrimination of specific odor patterns in the mammals.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Onoda N,Imamura K,Obata E,Iino Mdoi
10.1152/jn.1984.52.4.638subject
Has Abstractpub_date
1984-10-01 00:00:00pages
638-52issue
4eissn
0022-3077issn
1522-1598journal_volume
52pub_type
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