Response selectivity of neocortical neurons to specific odors in the rabbit.

Abstract:

:Odor responses of neocortical neurons in rabbits under light pentobarbital anesthesia were studied in a restricted area in the lateral half of the prefrontal cortex close to the frontal pole. A preevent cumulative sum chart provided a visual display of the change in unit discharge rate following each odor stimulation, and critical levels on each chart provided a visual display of statistical significance. The neocortical neurons studied were activated predominantly by biologically significant odors, such as feces, urine, and dry food. Of those same neurons, 90% failed to respond to pure-chemical odors, and no neurons were found that responded to pure-chemical odors alone. Some neurons responded exclusively to one of the animal-product odors. Some odor-sensitive neurons were affected by electrical stimulation of the mediodorsal thalamic nucleus. Responses to the animal-product odors were observed after ablation of the trigeminal and/or vomeronasal inputs. The responses to these pheromone-like substances are discussed in the context of a central role for odor-sensitive neocortical neurons in cognitive aspects of discrimination of specific odor patterns in the mammals.

journal_name

J Neurophysiol

authors

Onoda N,Imamura K,Obata E,Iino M

doi

10.1152/jn.1984.52.4.638

subject

Has Abstract

pub_date

1984-10-01 00:00:00

pages

638-52

issue

4

eissn

0022-3077

issn

1522-1598

journal_volume

52

pub_type

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