Search target selection in monkey prefrontal cortex.

abstract：:1. Long-term depression (LTD) is an activity-dependent reduction in the strength of synaptic transmission that can persist for hours. It is a neural model for processes underlying learning and memory, such as extinction and forgetting. LTD of excitatory postsynaptic potentials (EPSPs) in cells of the CA1 region of hip...

journal_title：Journal of neurophysiology

authors： Christofi G,Nowicky AV,Bolsover SR,Bindman LJ

更新日期：1993-01-01 00:00:00

abstract：:Second-order vestibular neurons (2 degrees VN) were identified in the isolated frog brain by the presence of monosynaptic excitatory postsynaptic potentials (EPSPs) after separate electrical stimulation of individual vestibular nerve branches. Combinations of one macular and the three semicircular canal nerve branches...

journal_title：Journal of neurophysiology

authors： Straka H,Holler S,Goto F

更新日期：2002-11-01 00:00:00

abstract：:Single neurons were recorded from the ventral posteromedial thalamic nucleus (VPM) of urethan-anesthetized rats. Six of these animals were intact, 28 sustained kainic acid (KA) lesions of trigeminal nucleus principalis (PrV), and 9 received similar lesions of trigeminal subnucleus interpolaris (SpVi). Four animals sus...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Belford GR,Killackey HP

更新日期：1987-05-01 00:00:00

abstract：:1. Extracellular and intracellular recordings from an isolated thoraco-abdominal preparation of the crayfish, Pacifastacus leniusculus, demonstrate that the swimmeret and the abdominal positioning systems can at times be spontaneously coordinated with each other. 2. Two forms of coordination were encountered between t...

journal_title：Journal of neurophysiology

authors： Chrachri A,Neil DM

更新日期：1993-05-01 00:00:00

abstract：:We investigated the topography of human cortical activation during an antisaccade task by focal transcranial magnetic stimulation (TMS). We used a figure-eight shaped coil, with the stimulus intensity set just above the threshold for activation of the hand motor areas but weak enough not to elicit blinks. TMS was deli...

journal_title：Journal of neurophysiology

authors： Terao Y,Fukuda H,Ugawa Y,Hikosaka O,Hanajima R,Furubayashi T,Sakai K,Miyauchi S,Sasaki Y,Kanazawa I

更新日期：1998-08-01 00:00:00

abstract：:The spinal cord has been well established as the site of generation of the locomotor rhythm in vertebrates, but studies have suggested that the caudal hindbrain in larval fish and amphibians can also generate locomotor rhythms. Here, we investigated whether the caudal hindbrain of the adult lamprey ( Petromyzon marinu...

journal_title：Journal of neurophysiology

authors： Buchanan JT

更新日期：2018-05-01 00:00:00

abstract：:1. The transmission in the spinal monosynaptic pathway was studied during repetitive stimulation of a motor nerve by 10 stimuli at 2, 5, or 10 Hz in spinal cats. Initially, the amplitudes of the monosynaptic responses rapidly declined, reaching a plateau after a few stimuli. The level of the plateau was inversely rela...

journal_title：Journal of neurophysiology

authors： Capek R,Esplin B

更新日期：1977-01-01 00:00:00

abstract：:The objective of this project was to examine the influence of stimulus waveform and frequency on extracellular stimulation of neurons with their cell bodies near the electrode (local cells) and fibers of passage in the CNS. Detailed computer-based models of CNS cells and axons were developed that accurately reproduced...

journal_title：Journal of neurophysiology

authors： McIntyre CC,Grill WM

更新日期：2002-10-01 00:00:00

abstract：:Internally generated, spontaneous activity is ubiquitous in the cortex, yet it does not appear to have a significant negative impact on sensory processing. Various studies have found that stimulus onset reduces the variability of cortical responses, but the characteristics of this suppression remained unexplored. By r...

journal_title：Journal of neurophysiology

authors： White B,Abbott LF,Fiser J

更新日期：2012-11-01 00:00:00

abstract：:1. We present a new mathematical description of the complete distribution of electrical responses to stochastic synaptic activity (quantal analysis) that is intended as a model of experiments on central neuronal synapses. Unlike previous treatments, this distribution is calculated for each instant after the release of...

journal_title：Journal of neurophysiology

authors： Blum KI,Idiart MA

更新日期：1994-09-01 00:00:00

abstract：:Based on kinematic properties and distinct substrates, there are different classes of eyelid movement described as eyeblinks. We investigate whether the eyelid movements made in response to a conditioned stimulus (CS) are a category of eyelid movements distinct from blinks. Human subjects received 60 trials of classic...

journal_title：Journal of neurophysiology

authors： Schade Powers A,Coburn-Litvak P,Evinger C

更新日期：2010-02-01 00:00:00

abstract：:1. In vagotomized, paralyzed, decerebrate cats, simultaneous recordings were taken from one or more sympathetic nerves [cervical sympathetic (CS), inferior cardiac (IC), splanchnic (SP)] and from medullary neurons in vasomotor-related regions. Coherence analyses were used to ascertain the presence of sympathetic rhyth...

journal_title：Journal of neurophysiology

authors： Cohen MI,Yu Q,Huang WX

更新日期：1995-07-01 00:00:00

abstract：:Gene delivery to the primate central nervous system via recombinant adeno-associated viral vectors (AAV) allows neurophysiologists to control and observe neural activity precisely. A current limitation of this approach is variability in vector transduction efficiency. Low levels of transduction can foil experimental m...

journal_title：Journal of neurophysiology

authors： Mendoza SD,El-Shamayleh Y,Horwitz GD

更新日期：2017-05-01 00:00:00

abstract：:Intrathecally applied nicotine reduces bradykinin-induced plasma extravasation (BK-induced PE) in the rat knee joint. This depression is mediated by the hypothalamo-pituitary-adrenal (HPA) axis and is enhanced by interruption of impulse traffic in afferents of the abdominal vagus nerve. Like intrathecal nicotine, elec...

journal_title：Journal of neurophysiology

authors： Miao FJ,Jänig W,Green PG,Levine JD

更新日期：1997-09-01 00:00:00

abstract：:How does the motor system choose the speed for any given movement? Many current models assume a process that finds the optimal balance between the costs of moving fast and the rewards of achieving the goal. Here, we show that such models also need to take into account a prior representation of preferred movement speed...

journal_title：Journal of neurophysiology

authors： Hammerbeck U,Yousif N,Greenwood R,Rothwell JC,Diedrichsen J

更新日期：2014-01-01 00:00:00

abstract：:1. Although it is generally agreed that Ca2+ couples depolarization to the release of neurotransmitters, hypertonic saline and ethanol (ETOH) evoke neurosecretion independent of extracellular Ca2+. One possible explanation is that these agents release Ca2+ from an intracellular store that then stimulates Ca(2+)-depend...

journal_title：Journal of neurophysiology

authors： Brosius DC,Hackett JT,Tuttle JB

更新日期：1992-10-01 00:00:00

abstract：:Spontaneous calcium oscillations in mushroom bodies of late stage pupal and adult Drosophila brains have been implicated in memory consolidation during olfactory associative learning. This study explores the cellular mechanisms regulating calcium dynamics in Kenyon cells, principal neurons in mushroom bodies. Fura-2 i...

journal_title：Journal of neurophysiology

authors： Jiang SA,Campusano JM,Su H,O'Dowd DK

更新日期：2005-07-01 00:00:00

abstract：:The voltage-gated K(+) channel Kv1.3 has been reported to regulate transmitter release in select central and peripheral neurons. In this study, we evaluated its role at the synapse between visceral sensory afferents and secondary neurons in the nucleus of the solitary tract (NTS). We identified mRNA and protein for Kv...

journal_title：Journal of neurophysiology

authors： Ramirez-Navarro A,Glazebrook PA,Kane-Sutton M,Padro C,Kline DD,Kunze DL

更新日期：2011-06-01 00:00:00

abstract：:When the brain has determined the position of a moving object, because of anatomical and processing delays the object will have already moved to a new location. Given the statistical regularities present in natural motion, the brain may have acquired compensatory mechanisms to minimize the mismatch between the perceiv...

journal_title：Journal of neurophysiology

authors： Subramaniyan M,Ecker AS,Patel SS,Cotton RJ,Bethge M,Pitkow X,Berens P,Tolias AS

更新日期：2018-11-01 00:00:00

abstract：:Spontaneous negative-going potentials occurring at an average frequency of 0.7 Hz were recorded from the dentate gyrus of slices prepared from the temporal hippocampus of young adult rats. These events (here termed "dentate waves") in several respects resembled the dentate spikes described for freely moving rats durin...

journal_title：Journal of neurophysiology

authors： Colgin LL,Kubota D,Brucher FA,Jia Y,Branyan E,Gall CM,Lynch G

更新日期：2004-12-01 00:00:00

abstract：:The parafacial respiratory group (pFRG), located in the lateral aspect of the rostroventral lateral medulla, has been described as a conditional expiratory oscillator that emerges mainly in conditions of high metabolic challenges to increase breathing. The convergence of inhibitory and excitatory inputs to pFRG and th...

journal_title：Journal of neurophysiology

authors： Silva JDN,Oliveira LM,Souza FC,Moreira TS,Takakura AC

更新日期：2020-05-01 00:00:00

abstract：:We studied adjustments in digit forces and moments during holding a vertically oriented handle under slow, externally imposed changes in the width of the grasp. Subjects (n = 8) grasped a customized motorized handle with five digits and held it statically in the air. The handle width either increased (expanded) or dec...

journal_title：Journal of neurophysiology

authors： Zatsiorsky VM,Gao F,Latash ML

更新日期：2006-04-01 00:00:00

abstract：:Support-surface movements are commonly used to examine balance control. Subjects typically receive a series of identical or randomly interspersed multidirectional balance perturbations and the atypical "first trial reaction" (evoked by the first perturbation) is often excluded from further analysis. However, this proc...

journal_title：Journal of neurophysiology

authors： Oude Nijhuis LB,Allum JH,Borm GF,Honegger F,Overeem S,Bloem BR

更新日期：2009-06-01 00:00:00

abstract：:Synaptic dynamics comprise a variety of interacting processes acting on a wide range of time scales. This enables a synapse to perform a large array of computations, from temporal and spatial filtering to associative learning. In this study, we describe how changing synaptic gain via long-term plasticity can act to sh...

journal_title：Journal of neurophysiology

authors： Lewis JE,Maler L

更新日期：2004-02-01 00:00:00

abstract：:The creation of several prestin knockout and knockin mouse lines has demonstrated the importance of the intrinsic outer hair cell membrane protein prestin to mammalian hearing. However, the structure of prestin remains largely unknown, with even its major features in dispute. Several studies have suggested that presti...

journal_title：Journal of neurophysiology

authors： Currall B,Rossino D,Jensen-Smith H,Hallworth R

更新日期：2011-11-01 00:00:00

abstract：:Whole cell voltage-clamp recordings from acutely isolated hippocampal CA1 pyramidal cells from adult guinea pigs were used to evaluate divalent cations as possible blockers of the postexposure current (Ipe). Ipe is a cation current that is triggered by the rise in intracellular Ca2+ concentration that occurs after the...

journal_title：Journal of neurophysiology

authors： Chen QX,Perkins KL,Wong RK

更新日期：1998-02-01 00:00:00

abstract：:Humans and songbirds shape learned vocalizations during a sensorimotor sensitive period or "babbling" phase. The brain mechanisms that underlie the shaping of vocalizations by sensory feedback are not known. We examined song behavior and brain activity in zebra finches during singing as they actively shaped their song...

journal_title：Journal of neurophysiology

authors： Crandall SR,Aoki N,Nick TA

更新日期：2007-01-01 00:00:00

abstract：:1. There is a long-standing debate about whether the large spiny cells in the hilar region of the hippocampus should be classified as pyramidal cells of Ammon's horn or as a distinct cell type of the dentate gyrus. The rationale for grouping these hilar neurons (termed "mossy cells") with pyramidal cells of Ammon's ho...

journal_title：Journal of neurophysiology

authors： Buckmaster PS,Strowbridge BW,Schwartzkroin PA

更新日期：1993-10-01 00:00:00

abstract：:In the hippocampus, the calcium-binding protein parvalbumin (PV) is expressed in interneurons that innervate perisomatic regions. PV in GABAergic synaptic terminals was proposed to limit repetitive GABA release by buffering of "residual calcium." We assessed the role of presynaptic PV in Ca(2+)-dependent GABA release ...

journal_title：Journal of neurophysiology

authors： Vreugdenhil M,Jefferys JG,Celio MR,Schwaller B

更新日期：2003-03-01 00:00:00

abstract：:1. Study of memory traces in higher animals requires experimental models possessing well-localized and technically accessible memory traces--plasticity responsible for behavioral change, not dependent on control from elsewhere, and open to detailed investigation. Our purpose has been to develop such a model based on t...

journal_title：Journal of neurophysiology

authors： Wolpaw JR,Lee CL

更新日期：1989-03-01 00:00:00