InsP3 causes an increase in apical [Ca2+]i by activating two distinct current components in vertebrate olfactory receptor cells.

abstract：:1. Effects of substance P (SP) and other tachykinins on membrane currents were investigated using whole cell voltage clamp in cultured sensory neurons isolated from rat dorsal root ganglia. 2. SP (100 nM) evoked an inward current in two-thirds of the cells at negative potentials. In most of the cells that generated th...

journal_title：Journal of neurophysiology

authors： Inoue K,Nakazawa K,Inoue K,Fujimori K

更新日期：1995-02-01 00:00:00

abstract：:Although studies of the principal tongue protrudor muscle genioglossus (GG) suggest that whole muscle GG electromyographic (EMG) activities are preserved in nonrapid eye movement (NREM) sleep, it is unclear what influence sleep exerts on individual GG motor unit (MU) activities. We characterized the firing patterns of...

journal_title：Journal of neurophysiology

authors： Bailey EF,Fridel KW,Rice AD

更新日期：2007-12-01 00:00:00

abstract：:In many rhythmic neuronal networks that operate in a wide range of frequencies, the time of neuronal firing relative to the cycle period (the phase) is invariant. This invariance suggests that when frequency changes, firing time is precisely adjusted either by intrinsic or synaptic mechanisms. We study the maintenance...

journal_title：Journal of neurophysiology

authors： Manor Y,Bose A,Booth V,Nadim F

更新日期：2003-11-01 00:00:00

abstract：:Synaptic dynamics comprise a variety of interacting processes acting on a wide range of time scales. This enables a synapse to perform a large array of computations, from temporal and spatial filtering to associative learning. In this study, we describe how changing synaptic gain via long-term plasticity can act to sh...

journal_title：Journal of neurophysiology

authors： Lewis JE,Maler L

更新日期：2004-02-01 00:00:00

abstract：:In addition to a primary somatosensory cortex (SI), the cerebral cortex of all mammals contains a second somatosensory area (SII); however, the functions of SII are largely unknown. Our aim was to explore the functions of SII by comparing response properties of whisker-related neurons in this area with their counterpa...

journal_title：Journal of neurophysiology

authors： Kwegyir-Afful EE,Keller A

更新日期：2004-10-01 00:00:00

abstract：:1. Using extracellular recording techniques in the CA1 region of the rat hippocampus, we have evaluated the effects of the redox reagents 5,5O-dithiobis-2-nitrobenzoic acid (DTNB) and tris (carboxyethyl) phosphine (TCEP) on long-term potentiation (LTP) expressed by alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic ...

journal_title：Journal of neurophysiology

authors： Gozlan H,Khazipov R,Diabira D,Ben-Ari Y

更新日期：1995-06-01 00:00:00

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00

abstract：:Perceptual decision making is often modeled as perfect integration of sequential sensory samples until the accumulated total reaches a fixed decision bound. In that view, the buildup of neural activity during perceptual decision making is attributed to temporal integration. However, an alternative explanation is that ...

journal_title：Journal of neurophysiology

authors： Carland MA,Marcos E,Thura D,Cisek P

更新日期：2016-02-01 00:00:00

abstract：:We investigated the postnatal development of axon sensitivity to the withdrawal of oxygen, glucose, or the combined withdrawal of oxygen + glucose in the isolated rat optic nerve (a CNS white matter tract). Removal of either oxygen or glucose for 60 min resulted in irreversible injury in optic nerves from adult rats, ...

journal_title：Journal of neurophysiology

authors： Fern R,Davis P,Waxman SG,Ransom BR

更新日期：1998-01-01 00:00:00

abstract：:Directional hearing is crucial for animals depending on acoustic signals to locate a mate. We focused on crickets to explore the reliability of directional information forwarded to the brain by the ascending auditory interneuron AN1, which is crucial for phonotactic behavior. We presented calling song from -45° to +45...

journal_title：Journal of neurophysiology

authors： Lv M,Zhang X,Hedwig B

更新日期：2020-03-01 00:00:00

abstract：:Glass micropipettes were used to record the activity of 124 single units in the somatosensory vibrissa cortex (SI) of 16 rats in response to combined deflections of contralateral vibrissae. Compact multiangular electromechanical stimulators were used to stimulate individual vibrissal hairs alone or in combinations of ...

journal_title：Journal of neurophysiology

authors： Simons DJ

更新日期：1985-09-01 00:00:00

abstract：:The marine mollusk Clione limacina, when swimming, can stabilize different body orientations in the gravitational field. The stabilization is based on the reflexes initiated by activation of the statocyst receptor cells and mediated by the cerebro-pedal interneurons that produce excitation of the motoneurons of the ef...

journal_title：Journal of neurophysiology

authors： Deliagina TG,Orlovsky GN,Selverston AI,Arshavsky YI

更新日期：2000-01-01 00:00:00

abstract：:1. Plasticity at the connections between sensory neurons and their follower cells in Aplysia has been used extensively as a model system to examine mechanisms of simple forms of learning. Earlier studies have concluded that serotonin (5-HT) is a key modulatory transmitter and that it exerts its short-term actions via ...

journal_title：Journal of neurophysiology

authors： Sugita S,Goldsmith JR,Baxter DA,Byrne JH

更新日期：1992-08-01 00:00:00

abstract：:Visual tracking of moving objects requires prediction to compensate for visual delays and minimize mismatches between eye and target position and velocity. In everyday life, objects often disappear behind an occluder, and prediction is required to align eye and target at reappearance. Earlier studies investigating eye...

journal_title：Journal of neurophysiology

authors： Orban de Xivry JJ,Bennett SJ,Lefèvre P,Barnes GR

更新日期：2006-01-01 00:00:00

abstract：:Visual tracking of moving targets requires the combination of smooth pursuit eye movements with catch-up saccades. In primates, catch-up saccades usually take place only during pursuit initiation because pursuit gain is close to unity. This contrasts with the lower and more variable gain of smooth pursuit in cats, whe...

journal_title：Journal of neurophysiology

authors： de Brouwer S,Missal M,Lefèvre P

更新日期：2001-08-01 00:00:00

abstract：:The countermanding saccade task has been used in many studies to investigate the neural mechanisms that underlie the decision to execute or restrain rapid eye movements. In this task, the presentation of a saccade target is sometimes followed by the appearance of a stop cue that indicates that the subject should cance...

journal_title：Journal of neurophysiology

authors： Walton MM,Gandhi NJ

更新日期：2006-10-01 00:00:00

abstract：:Neural regions in the dorsomedial frontal cortex (DMFC), including the supplementary eye field (SEF) and the presupplementary motor area (pre-SMA), are likely candidates for generating top-down control of saccade target selection. To investigate this, we applied electrical microstimulation to these structures while sa...

journal_title：Journal of neurophysiology

authors： Yang SN,Heinen SJ,Missal M

更新日期：2008-04-01 00:00:00

abstract：:Complex movements are generally thought to consist of a series of simpler elements. If this is so, how does the sensorimotor system assemble the pieces? This study recorded and evaluated sequences of arm movements to various targets placed in three-dimensional (3D) space. Subjects performed sequences consisting of sin...

journal_title：Journal of neurophysiology

authors： Klein Breteler MD,Hondzinski JM,Flanders M

更新日期：2003-06-01 00:00:00

abstract：:1. Whole-cell patch-clamp recordings of excitatory postsynaptic currents (EPSCs) were made from guinea pig hippocampal CA1 pyramidal cells. The sensitivity of paired pulse facilitation (PPF) and EPSC variance to changes in synaptic transmission was investigated and the results were compared with the changes in these p...

journal_title：Journal of neurophysiology

authors： Manabe T,Wyllie DJ,Perkel DJ,Nicoll RA

更新日期：1993-10-01 00:00:00

abstract：:The objectives of this study were to probe the contribution of spinal neuron persistent sodium conductances to reflex hyperexcitability in human chronic spinal cord injury. The intrinsic excitability of spinal neurons provides a novel target for medical intervention. Studies in animal models have shown that persistent...

journal_title：Journal of neurophysiology

authors： Theiss RD,Hornby TG,Rymer WZ,Schmit BD

更新日期：2011-06-01 00:00:00

abstract：:The caudal primate prefrontal cortex (PFC) is involved in target selection and visually guided saccades through both covert attention and overt orienting eye movements. Unilateral damage to the caudal PFC often leads to decreased awareness of a contralesional target alone, referred to as "neglect," or when it is prese...

journal_title：Journal of neurophysiology

authors： Adam R,Johnston K,Everling S

更新日期：2019-08-01 00:00:00

abstract：:Families of peptide neuromodulators are believed to play important roles in neural networks that control behaviors. Here, we investigate the expression and role of one such group of modulators, the myomodulins, in the feeding system of Lymnaea stagnalis. Using a combination of in situ hybridization and antibody staini...

journal_title：Journal of neurophysiology

authors： Perry SJ,Straub VA,Kemenes G,Santama N,Worster BM,Burke JF,Benjamin PR

更新日期：1998-05-01 00:00:00

abstract：:Glutamate-receptor-mediated synaptic transmission was studied in morphologically identified hippocampal dentate granule cells (DGCs; n = 31) with the use of whole cell patch-clamp recording and intracellular injection of biocytin or Lucifer yellow in slices prepared from surgically removed medial temporal lobe specime...

journal_title：Journal of neurophysiology

authors： Isokawa M,Levesque M,Fried I,Engel J Jr

更新日期：1997-06-01 00:00:00

abstract：:Voltage-gated Na+ channels (VGSC) are transmembrane proteins that are essential for the initiation and propagation of action potentials in neuronal excitability. Because neurons express a mixture of Na+ channel isoforms and protein kinase C (PKC) isozymes, the nature of which channel is being regulated by which PKC is...

journal_title：Journal of neurophysiology

authors： Vijayaragavan K,Boutjdir M,Chahine M

更新日期：2004-04-01 00:00:00

abstract：:Stability of images on the retina was determined in 14 normal humans in response to rotational and translational perturbations during self-generated pitch and yaw, standing, walking, and running on a treadmill. The effects on image stability of target distance, vision, and spectacle magnification were examined. During...

journal_title：Journal of neurophysiology

authors： Crane BT,Demer JL

更新日期：1997-10-01 00:00:00

abstract：:The responses of many neurons in primary visual cortex are modulated by stimuli outside the classical receptive field in ways that may contribute to integrative processes like scene segmentation. To explore this issue, single-unit neuronal responses were recorded in monkey cortical areas V1 and V2 to visual stimuli co...

journal_title：Journal of neurophysiology

authors： Marcus DS,Van Essen DC

更新日期：2002-11-01 00:00:00

abstract：:To explore a visual scene, the brain must detect an object of interest and direct the eyes to it. To investigate the brain's mechanism of saccade target selection, we trained monkeys to perform a visual search task with a response delay and recorded neuronal activity in the prefrontal (PF) cortex. Even though the monk...

journal_title：Journal of neurophysiology

authors： Hasegawa RP,Matsumoto M,Mikami A

更新日期：2000-09-01 00:00:00

abstract：:Recent studies have shown that sympathetic nervous system (SNS) activity can be heavily impacted not only by basic threats to survival but also by threats to social bonds. In this study we explored the behavioral and physiological consequences of social exclusion/inclusion in patients with psoriasis, a disease frequen...

journal_title：Journal of neurophysiology

authors： Ponsi G,Monachesi B,Panasiti V,Aglioti SM,Panasiti MS

更新日期：2019-01-01 00:00:00

abstract：:The human ventral visual pathway is implicated in higher order form processing, but the organizational principles within this region are not yet well understood. Recently, Lafer-Sousa, Conway, and Kanwisher (J Neurosci 36: 1682-1697, 2016) used functional magnetic resonance imaging to demonstrate that functional respo...

journal_title：Journal of neurophysiology

authors： Goddard E

更新日期：2017-03-01 00:00:00

abstract：:Itch is often triggered by warming the skin in patients with itchy dermatitis, but the underlying mechanism is largely unknown. We presently investigated if warming the skin enhances histamine- or serotonin (5-HT)-evoked itch behavior or responses of sensory dorsal root ganglion (DRG) cells, and if responses of superf...

journal_title：Journal of neurophysiology

authors： Akiyama T,Nagamine M,Davoodi A,Ivanov M,Carstens MI,Carstens E

更新日期：2017-01-01 00:00:00