In CA1 hippocampal neurons, the redox state of NMDA receptors determines LTP expressed by NMDA but not by AMPA receptors.

abstract：:Primates have a remarkable ability to perceive, recognize, and discriminate among the plethora of people, places, and things that they see, and neural selectivity in the primate inferotemporal (IT) cortex is thought to underlie this ability. Here we investigated the relationship between neural response and perception ...

journal_title：Journal of neurophysiology

authors： Allred S,Liu Y,Jagadeesh B

更新日期：2005-12-01 00:00:00

abstract：:The primate superior colliculus (SC) is causally involved in microsaccade generation. Moreover, visually responsive SC neurons across this structure's topographic map, even at peripheral eccentricities much larger than the tiny microsaccade amplitudes, exhibit significant modulations of evoked response sensitivity whe...

journal_title：Journal of neurophysiology

authors： Khademi F,Chen CY,Hafed ZM

更新日期：2020-06-01 00:00:00

abstract：:Whole cell voltage-clamp techniques were employed to characterize the sodium (Na) conductances in acutely dissociated, mature guinea-pig cerebellar Purkinje cells. Three phenomenological components were noted: two inactivating and a persistent component (I(P)(Na). All exhibited similar sensitivities to tetrodotoxin (T...

journal_title：Journal of neurophysiology

authors： Kay AR,Sugimori M,Llinás R

更新日期：1998-09-01 00:00:00

abstract：:In this report, we provide the first characterization of abducens nucleus neuron (ABN) discharge dynamics during horizontal disjunctive saccades. These movements function to rapidly transfer the visual axes between targets located at different eccentricities and depths. Our primary objective was to determine whether t...

journal_title：Journal of neurophysiology

authors： Sylvestre PA,Cullen KE

更新日期：2002-12-01 00:00:00

abstract：:An acute experimental arthritis was induced in the right knee joint of adult cats anesthetized with chloralose, and the activity of single fine afferent units of the medial articular nerve was recorded from filaments of the saphenous nerve. All units included in this study were sensitive to local mechanical probing of...

journal_title：Journal of neurophysiology

authors： Schaible HG,Schmidt RF

更新日期：1985-11-01 00:00:00

abstract：:We cloned 10 full-length variants of PIIH, the gene for I(h) from the spiny lobster, Panulirus interruptus, using reverse transcription-PCR (RT-PCR) and rapid amplification of cDNA ends (RACE). This gene shows a significant amount of alternative splicing in the S3-S4 and S4-S5 linkers, in the P-loop and the entire S6 ...

journal_title：Journal of neurophysiology

authors： Ouyang Q,Goeritz M,Harris-Warrick RM

更新日期：2007-06-01 00:00:00

abstract：:The characteristics of the primary afferent depolarization (PAD) of Ia- and Ib-fibers generated by segmental and descending inputs have been analyzed in the spinal cord of anesthetized cats. The PAD was inferred from the changes produced by conditioning inputs on the intraspinal stimulus current required to produce a ...

journal_title：Journal of neurophysiology

authors： Rudomin P,Solodkin M,Jiménez I

更新日期：1986-10-01 00:00:00

abstract：:1. The sensorimotor synapse of Aplysia expresses various shortlasting changes in synaptic efficacy including homosynaptic depression (HSD) and heterosynaptic facilitation by serotonin (5-HT) either at nondepressed sensory neuron (SN) synaptic connections or at SN synaptic connections first depressed by HSD. We examine...

journal_title：Journal of neurophysiology

authors： Sun ZY,Schacher S

更新日期：1996-10-01 00:00:00

abstract：:The role of potassium channels in regulating spontaneous firing and sound-evoked responses in the central nucleus of the inferior colliculus was studied by recording single-unit activity before and during iontophoretic application of a nonspecific potassium channel blocker, tetraethylammonium (TEA). Tone bursts and si...

journal_title：Journal of neurophysiology

authors： Zhang H,Wu SH,Kelly JB

更新日期：2004-05-01 00:00:00

abstract：:The short-term (3-51 days) and long-term (31-42 wk) effects of corpus callosum transection on the receptive-field properties of neurons were assessed at the single-cell, architectural, and topographical levels of organization in the cat striate cortex. Corpus callosum transection decreased the proportion of neurons th...

journal_title：Journal of neurophysiology

authors： Payne BR,Pearson HE,Berman N

更新日期：1984-09-01 00:00:00

abstract：:1. The effect of cholinergic receptor activation on gamma-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission was investigated in voltage-clamped CA1 pyramidal neurons (HPNs) in the guinea pig hippocampal slice preparation. 2. The cholinergic agonist carbachol (1-10 microM) induced a prominent and susta...

journal_title：Journal of neurophysiology

authors： Behrends JC,ten Bruggencate G

更新日期：1993-02-01 00:00:00

abstract：:1. Behavioral studies in the monkey and clinical studies in humans show that some visuomotor functions are spared in case of a V1 lesion. This residual vision appears to be subserved at least partially by visual activity in extrastriate cortex. Earlier studies have demonstrated that neurons in area V2 lose their visua...

journal_title：Journal of neurophysiology

authors： Girard P,Salin PA,Bullier J

更新日期：1991-11-01 00:00:00

abstract：:It has recently become clear that microglia, the immune cells of the central nervous system, are far more active in the healthy brain than previously thought. Microglia facilitate many stages of brain development by shaping neuronal connectivity via synaptic elimination. Dysfunction of these same processes likely unde...

journal_title：Journal of neurophysiology

authors： Whitelaw BS

更新日期：2018-01-01 00:00:00

abstract：:Sexually dimorphic behaviors develop under the influence of sex steroids, which induce reversible changes in the underlying neural network of the brain. However, little is known about the proteins that mediate these activational effects of sex steroids. Here, we used a proteomics approach for large-scale identificatio...

journal_title：Journal of neurophysiology

authors： Zupanc GK,Ilies I,Sîrbulescu RF,Zupanc MM

更新日期：2014-04-01 00:00:00

abstract：:1. Neurons in the ventral intraparietal area (VIP) are known to respond to translating random dot patterns. Such responses can be explained on the basis of the input of the middle temporal area (MT) to this area. Anatomic evidence has shown that VIP receives input from the dorsal part of the medial superior temporal a...

journal_title：Journal of neurophysiology

authors： Schaafsma SJ,Duysens J

更新日期：1996-12-01 00:00:00

abstract：:1. Adult rats and rats with a postnatal age of 3-29 days (PN 3-29) were used for the preparation of in vitro slices of the frontal neocortex. Epileptiform activity was induced by bath application of the gamma-aminobutyric acid-A (GABAA) receptor antagonists bicuculline or picrotoxin. 2. The voltage-sensitive dye RH 41...

journal_title：Journal of neurophysiology

authors： Sutor B,Hablitz JJ,Rucker F,ten Bruggencate G

更新日期：1994-10-01 00:00:00

abstract：:1. Spontaneous saccades, vestibuloocular responses (VOR), and optokinetic nystagmus were recorded in three squirrel monkeys before and after chemical or electrolytic lesion of the posterior commissure (PC). 2. PC lesions produced abnormal vertical eye movements, in particular, 1) Postsaccadic drifts, and 2) VOR gain r...

journal_title：Journal of neurophysiology

authors： Partsalis AM,Highstein SM,Moschovakis AK

更新日期：1994-06-01 00:00:00

abstract：:1. Intracellular recordings were made from neurons of the basolateral amygdala (BLA) in in vitro slice preparations to determine long-term differences in metabotropic glutamate receptor (mGluR) agonist-induced membrane responses in control and amygdala-kindled rats. 2. (2S,3S,4S)-alpha-(carboxycyclopropyl)glycine-1 (L...

journal_title：Journal of neurophysiology

authors： Holmes KH,Keele NB,Shinnick-Gallagher P

更新日期：1996-10-01 00:00:00

abstract：:Voluntary and stimulus-driven shifts of attention can modulate the representation of behaviorally relevant stimuli in early areas of visual cortex. In turn, attended items are processed faster and more accurately, facilitating the selection of appropriate behavioral responses. Information processing is also strongly i...

journal_title：Journal of neurophysiology

authors： Serences JT,Saproo S

更新日期：2010-07-01 00:00:00

abstract：:1. The statistical properties of the bursting potassium channel from fused Torpedo synaptosomes were studied by using patch-clamp recording and time series analysis. 2. Voltage steps produce channel openings; the number of channels opening fluctuates from trial to trial. The maximal current observed in each trial is s...

journal_title：Journal of neurophysiology

authors： Rahamimoff R,Edry-Schiller J,Ginsburg S

更新日期：1992-12-01 00:00:00

abstract：:In the auditory system of the big brown bat (Eptesicus fuscus), paired conditioned tonal (CS) and unconditioned leg stimuli (US) for auditory fear conditioning elicit tone-specific plasticity represented by best-frequency (BF) shifts that are augmented by acetylcholine, whereas unpaired CS and US for pseudoconditionin...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N

更新日期：2013-02-01 00:00:00

abstract：:We presented optic flow and real movement heading stimuli while recording MSTd neuronal activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow heading perturbations, vestibular detection of real movement heading perturbations, and auditory detection of brief tones. Push-button RTs we...

journal_title：Journal of neurophysiology

authors： Page WK,Duffy CJ

更新日期：2018-01-01 00:00:00

abstract：:Experimental evidence supports a number of mechanisms for the synaptic change that occurs with long-term potentiation (LTP) including insertion of AMPA receptors, an increase in AMPA receptor single channel conductance, unmasking silent synapses, and increases in vesicle release probability. Here we combine experiment...

journal_title：Journal of neurophysiology

authors： Holmes WR,Grover LM

更新日期：2006-09-01 00:00:00

abstract：:1. The properties of parietal neurons were studied in four adult rhesus monkeys during fast arm movements. The animals were trained to perform flexion or extension of the forearm about the elbow in response to specific auditory cues. Single neuron activity was recorded in 272 area 5 neurons, 81 neurons of the somatose...

journal_title：Journal of neurophysiology

authors： Burbaud P,Doegle C,Gross C,Bioulac B

更新日期：1991-08-01 00:00:00

abstract：:The responses of low-frequency, primary-like neurons of the ventral cochlear nucleus were measured as a function of signal-to-noise ratio for gated tonal signals and noise maskers that were varied in bandwidth and duration. For a given signal-to-noise ratio, each of the maskers is known to produce the same amount of m...

journal_title：Journal of neurophysiology

authors： Langford TL

更新日期：1983-12-01 00:00:00

abstract：:Successful navigation requires a constantly updated neural representation of directional heading, which is conveyed by head direction (HD) cells. The HD signal is predominantly controlled by visual landmarks, but when familiar landmarks are unavailable, self-motion cues are able to control the HD signal via path integ...

journal_title：Journal of neurophysiology

authors： Yoder RM,Clark BJ,Brown JE,Lamia MV,Valerio S,Shinder ME,Taube JS

更新日期：2011-06-01 00:00:00

abstract：:This study reexamined the perceptual equivalence of active and passive touch using a computer-controlled force-feedback device. Nine subjects explored a 6 x 10-cm workspace, with the index finger resting on a mobile flat plate, and experienced simulated Gaussian ridges and troughs (width, 15 mm; amplitude, 0.5 to 4.5 ...

journal_title：Journal of neurophysiology

authors： Smith AM,Chapman CE,Donati F,Fortier-Poisson P,Hayward V

更新日期：2009-12-01 00:00:00

abstract：:Fast inhibitory synaptic transmission in the brain relies on ionotropic GABA(A) receptors (GABA(A)R). Eighteen genes code for GABA(A)R subunits, but little is known about the epsilon subunit. Our aim was to identify the synaptic transmission properties displayed by native receptors incorporating epsilon. Immunogold lo...

journal_title：Journal of neurophysiology

authors： Belujon P,Baufreton J,Grandoso L,Boué-Grabot E,Batten TF,Ugedo L,Garret M,Taupignon AI

更新日期：2009-10-01 00:00:00

abstract：:Temporal and spatial correlations between auditory and visual stimuli facilitate the perception of unitary events and improve behavioral responses. However, it is not clear how combined visual and auditory information is processed in single neurons. Here we studied responses of multisensory neurons in the barn owl's o...

journal_title：Journal of neurophysiology

authors： Zahar Y,Reches A,Gutfreund Y

更新日期：2009-05-01 00:00:00

abstract：:At many glutamatergic synapses, non-N-methyl-d-aspartate (NMDA) and NMDA receptors are coexpressed postsynaptically. In the mammalian retina, glutamatergic rod bipolar cells are presynaptic to two rod amacrine cells (AII and A17) that constitute dyad postsynaptic partners opposite each presynaptic active zone. Whereas...

journal_title：Journal of neurophysiology

authors： Zhou Y,Tencerová B,Hartveit E,Veruki ML

更新日期：2016-01-01 00:00:00