Loss of mGluR-mediated hyperpolarizations and increase in mGluR depolarizations in basolateral amygdala neurons in kindling-induced epilepsy.

abstract：:1. The heart of the nudibranch mollusc Archidoris montereyensis is uniquely responsive to regulation by identifiable cardiac motor neurons. The neurotransmitters mediating the strong excitatory and inhibitory actions of the neurons are unknown. 2. In this study we developed an infused, in vitro preparation of the Arch...

journal_title：Journal of neurophysiology

authors： Wiens BL,Brownell PH

更新日期：1995-10-01 00:00:00

abstract：:Humans maneuver easily over uneven terrain. To maintain smooth and efficient gait the motor system needs to adapt the locomotor output to the walking environment. In the present study we investigate the role of sensory feedback in adjusting the soleus muscle activity during overground walking in 19 healthy volunteers....

journal_title：Journal of neurophysiology

authors： Af Klint R,Nielsen JB,Sinkjaer T,Grey MJ

更新日期：2009-04-01 00:00:00

abstract：:Conjugate eye movements in the horizontal plane are accomplished by the coactivation of the medial rectus (MR) muscle of one orbit and the lateral rectus (LR) muscle of the other. While control of these excursions has been thought to be effected by identical inputs to these muscles, recent studies have demonstrated th...

journal_title：Journal of neurophysiology

authors： Meredith MA,Goldberg SJ

更新日期：1986-07-01 00:00:00

abstract：:Noise is a major concern in circuits processing electrical signals, including neural circuits. There are many factors that influence how noise propagates through neural circuits, and there are few systems in which noise levels have been studied throughout a processing pathway. We recorded intracellularly from multiple...

journal_title：Journal of neurophysiology

authors： Jones PW,Gabbiani F

更新日期：2012-02-01 00:00:00

abstract：:Gramicidin-perforated patch-clamp recordings were made from slices of the suprachiasmatic nucleus (SCN) of adult rats to characterize the role of gamma-amino butyric acid (GABA) in the circadian timing system. During the day, activation of GABA(A) receptors hyperpolarized the membrane of SCN neurons. During the night,...

journal_title：Journal of neurophysiology

authors： De Jeu M,Pennartz C

更新日期：2002-02-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:Populations of output neurons in the mammalian olfactory bulb (OB) exhibit distinct, widespread spatial and temporal activation patterns when stimulated with odorants. However, questions remain as to how ensembles of mitral/tufted (M/T) neurons in the mammalian OB represent odorant information. In this report, the sin...

journal_title：Journal of neurophysiology

authors： Lehmkuhle MJ,Normann RA,Maynard EM

更新日期：2006-03-01 00:00:00

abstract：:It has been suggested that successively presented sounds that are perceived as separate auditory streams are represented by separate populations of neurons. Mostly, spectral separation in different peripheral filters has been identified as the cue for segregation. However, stream segregation based on temporal cues is ...

journal_title：Journal of neurophysiology

authors： Itatani N,Klump GM

更新日期：2011-01-01 00:00:00

abstract：:Several qualitative features distinguish bipedal from quadrupedal locomotion in mammals. In this study we show quantitative differences between quadrupedal and bipedal gait in the Japanese monkey in terms of gait patterns, trunk/hindlimb kinematics, and electromyographic (EMG) activity, obtained from 3 macaques during...

journal_title：Journal of neurophysiology

authors： Higurashi Y,Maier MA,Nakajima K,Morita K,Fujiki S,Aoi S,Mori F,Murata A,Inase M

更新日期：2019-07-01 00:00:00

abstract：:Binocular disparity, the slight differences between the images registered by our two eyes, provides an important cue when estimating the three-dimensional (3D) structure of the complex environment we inhabit. Sensitivity to binocular disparity is evident at multiple levels of the visual hierarchy in the primate brain,...

journal_title：Journal of neurophysiology

authors： Chandrasekaran C,Canon V,Dahmen JC,Kourtzi Z,Welchman AE

更新日期：2007-02-01 00:00:00

abstract：:To perform goal-oriented hand movement, humans combine multiple sensory signals (e.g., vision and proprioception) that can be encoded in various reference frames (body centered and/or exo-centered). In a previous study (Tagliabue M, McIntyre J. PLoS One 8: e68438, 2013), we showed that, when aligning a hand to a remem...

journal_title：Journal of neurophysiology

authors： Arnoux L,Fromentin S,Farotto D,Beraneck M,McIntyre J,Tagliabue M

更新日期：2017-09-01 00:00:00

abstract：:Single pulses of transcranial magnetic stimulation (TMS) result in distal and long-lasting oscillations, a finding directly challenging the virtual lesion hypothesis. Previous research supporting this finding has primarily come from stimulation of the motor cortex. We have used single-pulse TMS with simultaneous EEG t...

journal_title：Journal of neurophysiology

authors： Garcia JO,Grossman ED,Srinivasan R

更新日期：2011-10-01 00:00:00

abstract：:Hyolaryngeal elevation is essential for airway protection during swallowing and is mainly a reflexive response to oropharyngeal sensory stimulation. Targeted intramuscular electrical stimulation can elevate the resting larynx and, if applied during swallowing, may improve airway protection in dysphagic patients with i...

journal_title：Journal of neurophysiology

authors： Burnett TA,Mann EA,Stoklosa JB,Ludlow CL

更新日期：2005-12-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:We assessed synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) properties during synaptogenesis to describe the development of individual glutamatergic synapses on rat hippocampal CA1 principal neurons. Pharmacologically isolated AMPAR-mediated glutamatergic synaptic currents [evoked by stimul...

journal_title：Journal of neurophysiology

authors： Stubblefield EA,Benke TA

更新日期：2010-10-01 00:00:00

abstract：:Under constant light-adapted conditions, vision seems to be rather linear. However, the processes underlying the synaptic transmission between cones and second-order neurons (bipolar cells and horizontal cells) are highly nonlinear. In this paper, the gain-characteristics of the transmission from cones to horizontal c...

journal_title：Journal of neurophysiology

authors： Kraaij DA,Spekreijse H,Kamermans M

更新日期：2000-09-01 00:00:00

abstract：:An acute experimental arthritis was induced in the right knee joint of adult cats anesthetized with chloralose, and the activity of single fine afferent units of the medial articular nerve was recorded from filaments of the saphenous nerve. All units included in this study were sensitive to local mechanical probing of...

journal_title：Journal of neurophysiology

authors： Schaible HG,Schmidt RF

更新日期：1985-11-01 00:00:00

abstract：:1. The shared inputs to cat retinal ganglion cells have been investigated by studying correlations in the maintained firing of neighboring ganglion cells. The firing of one cell was recorded from its axon in the optic tract, while that of a neighboring cell was simultaneously recorded with a second electrode in the re...

journal_title：Journal of neurophysiology

authors： Mastronarde DN

更新日期：1983-02-01 00:00:00

abstract：:1. Recurrent inhibitory postsynaptic potentials (IPSPs) to and from motoneurons innervating the flexor digitorum longus (FDL) and flexor hallucis longus (FHL) muscles of the cat were investigated to determine whether recurrent inhibitory projections involving these motoneurons are similar--as would be consistent with ...

journal_title：Journal of neurophysiology

authors： Hamm TM

更新日期：1990-03-01 00:00:00

abstract：:Microstimulation within the motor regions of the spinal cord is often assumed to activate motoneurons and propriospinal neurons close to the electrode tip. However, previous work has shown that intraspinal microstimulation (ISMS) in the gray matter activates sensory afferent axons as well as alpha-motoneurons (MNs). H...

journal_title：Journal of neurophysiology

authors： Gaunt RA,Prochazka A,Mushahwar VK,Guevremont L,Ellaway PH

更新日期：2006-12-01 00:00:00

abstract：:We asked whether podokinetic adaptation to walking on a circular treadmill transfers to different forms of locomotion. Subjects were blindfolded and asked to walk straight across the floor, in the forward and backward directions, following podokinetic (PK) stimulation that consisted of 30 min of forward walking-in-pla...

journal_title：Journal of neurophysiology

authors： Earhart GM,Jones GM,Horak FB,Block EW,Weber KD,Fletcher WA

更新日期：2001-10-01 00:00:00

abstract：:The medial superior temporal area of the macaque monkey extrastriate visual cortex can be divided into a dorsal medial (MSTd) and a lateral ventral (MSTl) region. The functions of the two regions may not be identical: MSTd may process optic flow information that results from the movement of the observer, whereas MSTl ...

journal_title：Journal of neurophysiology

authors： Eifuku S,Wurtz RH

更新日期：1998-07-01 00:00:00

abstract：:Properties of calcium spikes revealed during GABAA receptor antagonism in hippocampal CA1 neurons from guinea pigs. J. Neurophysiol. 78: 2269-2279, 1997. Intracellular electrical responses and changes in intracellular calcium concentration ([Ca2+]i) in response to activation of synaptic inputs and to DC injections wer...

journal_title：Journal of neurophysiology

authors： Miura M,Yoshioka M,Miyakawa H,Kato H,Ito KI

更新日期：1997-11-01 00:00:00

abstract：:Hippocampal neurons show a strong modulation by theta frequency oscillations. This modulation is thought to be important not only for temporal encoding and decoding of information in the hippocampal system, but also for temporal ordering of neuronal activities on timescales at which physiological mechanisms of synapti...

journal_title：Journal of neurophysiology

authors： Deshmukh SS,Yoganarasimha D,Voicu H,Knierim JJ

更新日期：2010-08-01 00:00:00

abstract：:Using whole cell patch-clamp recordings, we examined the effect of colchicine, a microtubule disrupter, on the properties of glycine receptors (GlyRs) in cultured spinal cord neurons. Confocal microscopy revealed that colchicine treatment effectively altered microtubule bundles and neuronal morphology. Application of ...

journal_title：Journal of neurophysiology

authors： van Zundert B,Alvarez FJ,Yevenes GE,Cárcamo JG,Vera JC,Aguayo LG

更新日期：2002-01-01 00:00:00

abstract：:Without intervention after spinal cord injury (SCI), paralyzed skeletal muscles undergo myofiber atrophy and slow-to-fast myofiber type transformations. We hypothesized that chronic spasticity-associated neuromuscular activity after SCI would promote recovery from such deleterious changes. We examined segmental tail m...

journal_title：Journal of neurophysiology

authors： Harris RL,Putman CT,Rank M,Sanelli L,Bennett DJ

更新日期：2007-02-01 00:00:00

abstract：:1. H reflexes were elicited in the second interosseous muscle of the hindpaw of the anesthetized dog during passive rotation of the shank about the ipsilateral or contralateral knee. Reflexes sampled at four points in the cycle of movement were compared with stationary controls. For both the ipsilateral and contralate...

journal_title：Journal of neurophysiology

authors： Misiaszek JE,Barclay JK,Brooke JD

更新日期：1996-11-01 00:00:00

abstract：:The forebrain plays an important role in many aspects of sound localization behavior. Yet, the forebrain pathway that processes auditory spatial information is not known for any species. Using standard anatomic labeling techniques, we used a "top-down" approach to trace the flow of auditory spatial information from an...

journal_title：Journal of neurophysiology

authors： Cohen YE,Miller GL,Knudsen EI

更新日期：1998-02-01 00:00:00

abstract：:1. The kinetic properties of embryonic Xenopus spinal cord neuron N-methyl-D-aspartate (NMDA)-activated receptors (NMDAR) were examined at the single-channel level. These receptors have a main conductance state of 50 pS and make occasional sojourns to a subconductance level of approximately 40 pS. The open channel lif...

journal_title：Journal of neurophysiology

authors： Zhang Y,Auerbach A

更新日期：1995-07-01 00:00:00

abstract：:The oculomotor system is well understood compared with other motor systems; however, we do not yet know the spatial details of sensory to motor transformations. This study addresses this issue by quantifying the spatial relationships between visual and motor responses in the superior colliculus (SC), a midbrain struct...

journal_title：Journal of neurophysiology

authors： Marino RA,Rodgers CK,Levy R,Munoz DP

更新日期：2008-11-01 00:00:00