Intraspinal microstimulation excites multisegmental sensory afferents at lower stimulus levels than local alpha-motoneuron responses.

abstract：:The generation of a behaviorally relevant cue to the speed of objects around us is critical to our ability to navigate safely within our environment. However, our perception of speed is often distorted by prevailing conditions. For instance, as luminance is reduced, our perception of the speed of fast-moving patterns ...

journal_title：Journal of neurophysiology

authors： Hammett ST,Smith AT,Wall MB,Larsson J

更新日期：2013-08-01 00:00:00

abstract：:The function of the ventral nucleus of the lateral lemniscus (VNLL), a secondary processing site within the auditory brain stem, is unclear. It is known to be a major source of inhibition to the inferior colliculus (IC). It is also thought to play a role in coding the temporal aspects of sound, such as onsets and the ...

journal_title：Journal of neurophysiology

authors： Nayagam DA,Clarey JC,Paolini AG

更新日期：2005-08-01 00:00:00

abstract：:Smooth pursuit eye movements are driven by retinal motion signals. These retinal motion signals are converted into motor commands that obey Listing's law (i.e., no accumulation of ocular torsion). The fact that smooth pursuit follows Listing's law is often taken as evidence that no explicit reference frame transformat...

journal_title：Journal of neurophysiology

authors： Blohm G,Lefèvre P

更新日期：2010-10-01 00:00:00

abstract：:Distinguishing which of the many proposed neural mechanisms of spatial attention actually underlies behavioral improvements in visually guided tasks has been difficult. One attractive hypothesis is that attention allows downstream neural circuits to selectively integrate responses from the most informative sensory neu...

journal_title：Journal of neurophysiology

authors： Masse NY,Herrington TM,Cook EP

更新日期：2012-09-01 00:00:00

abstract：:Impulse from soleus muscle afferents were recorded in premammillary cats that were walking on a treadmill. In normal walking the effects of gamma-motoneurons on impulse rates of muscle spindle afferents are confounded by the effects of the large length changes that occur. To isolate the effects of gamma-motoneurons th...

journal_title：Journal of neurophysiology

authors： Taylor J,Stein RB,Murphy PR

更新日期：1985-02-01 00:00:00

abstract：:The timing of brief stationary sounds has been shown to alter the perceived speed of visual apparent motion (AM), presumably by altering the perceived timing of the individual frames of the AM stimuli and/or the duration of the interstimulus intervals (ISIs) between those frames. To investigate the neural correlates o...

journal_title：Journal of neurophysiology

authors： Kafaligonul H,Albright TD,Stoner GR

更新日期：2018-09-01 00:00:00

abstract：:1. The purpose of this study was 1) to characterize the decrease observed in mean firing rates of motor units in the first 8-15 s of isometric constant-force contractions and 2) to investigate possible mechanisms that could account for the ability to maintain force output in the presence of decreasing motor unit firin...

journal_title：Journal of neurophysiology

authors： de Luca CJ,Foley PJ,Erim Z

更新日期：1996-09-01 00:00:00

abstract：:We used multiunit recording to assess the effect of rotating one eye approximately 90 degrees at about the time of normal eye opening. Rotation of the eye did not alter the topography of the retinal maps onto visual cortex or superior colliculus. The intorted eye drove cells at most recording points in the contralater...

journal_title：Journal of neurophysiology

authors： Gordon B,Moran J,Presson J

更新日期：1983-09-01 00:00:00

abstract：:Dopaminergic modulation of neuronal networks in the dorsolateral prefrontal cortex (PFC) is believed to play an important role in information processing during working memory tasks in both humans and nonhuman primates. To understand the basic cellular mechanisms that underlie these actions of dopamine (DA), we have in...

journal_title：Journal of neurophysiology

authors： Henze DA,González-Burgos GR,Urban NN,Lewis DA,Barrionuevo G

更新日期：2000-12-01 00:00:00

abstract：:The dorsal nucleus of the lateral lemniscus (DNLL) receives afferent inputs from many brain stem nuclei and, in turn, is a major source of inhibitory inputs to the inferior colliculus (IC). The goal of this study was to characterize the monaural and binaural response properties of neurons in the DNLL of unanesthetized...

journal_title：Journal of neurophysiology

authors： Davis KA,Lomakin O,Pesavento MJ

更新日期：2007-09-01 00:00:00

abstract：:The present study was undertaken to explore the neuronal mechanisms responsible for muscle atonia that occurs after the microinjection of bicuculline into the nucleus pontis oralis (NPO). Specifically, we wished to test the hypothesis that motoneurons are postsynaptically inhibited after the microinjection of bicucull...

journal_title：Journal of neurophysiology

authors： Xi MC,Morales FR,Chase MH

更新日期：2001-10-01 00:00:00

abstract：:AMPA-type glutamate receptors are normally Ca(2+) impermeable due to the expression of the GluR2 receptor subunit. By using GluR2 null mice we were able to detect miniature synaptic Ca(2+) transients (MSCTs) associated with AMPA-type receptor-mediated miniature synaptic currents at single synapses in primary cortical ...

journal_title：Journal of neurophysiology

authors： Wang S,Jia Z,Roder J,Murphy TH

更新日期：2002-07-01 00:00:00

abstract：:Impairments in human motor patterns are complex: what is often observed as a single global deficit (e.g., limping when walking) is actually the sum of several distinct abnormalities. Motor adaptation can be useful to teach patients more normal motor patterns, yet conventional training paradigms focus on individual fea...

journal_title：Journal of neurophysiology

authors： Statton MA,Toliver A,Bastian AJ

更新日期：2016-05-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) play an important role in cell survival versus cell death decisions during neuronal development, ischemia, trauma, and epilepsy. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all these conditions. In the developing CN...

journal_title：Journal of neurophysiology

authors： Wang Y,Denisova JV,Kang KS,Fontes JD,Zhu BT,Belousov AB

更新日期：2010-12-01 00:00:00

abstract：:Corneal-responsive neurons were recorded extracellularly in two regions of the spinal trigeminal nucleus, subnucleus interpolaris/caudalis (Vi/Vc) and subnucleus caudalis/upper cervical cord (Vc/C1) transition regions, from methohexital-anesthetized male rats. Thirty-nine Vi/Vc and 26 Vc/C1 neurons that responded to m...

journal_title：Journal of neurophysiology

authors： Hirata H,Hu JW,Bereiter DA

更新日期：1999-11-01 00:00:00

abstract：:Pain signals threat and initiates motor responses to avoid harm. The transformation of pain into a motor response is thus an essential part of pain. Here, we investigated the neural mechanisms subserving the sensorimotor transformation of pain at the cortical level by using electroencephalography. In a simple reaction...

journal_title：Journal of neurophysiology

authors： Schulz E,Tiemann L,Witkovsky V,Schmidt P,Ploner M

更新日期：2012-08-01 00:00:00

abstract：:Extracellular single-unit recordings were used to characterize responses of thalamic barreloid and cortical barrel neurons to controlled whisker deflections in 2, 3-, and 4-wk-old and adult rats in vivo under fentanyl analgesia. Results indicate that response properties of thalamic and cortical neurons diverge during ...

journal_title：Journal of neurophysiology

authors： Shoykhet M,Simons DJ

更新日期：2008-01-01 00:00:00

abstract：:The dendritic tree of layer 5 (L5) pyramidal neurons spans the neocortical layers, allowing the integration of intra- and extracortical synaptic inputs. Here we investigate the postnatal development of the integrative properties of rat L5 pyramidal neurons using simultaneous whole cell recording from the soma and dist...

journal_title：Journal of neurophysiology

authors： Atkinson SE,Williams SR

更新日期：2009-08-01 00:00:00

abstract：:Slowness of voluntary movements in patients with multiple sclerosis (MS) may be due to various factors, including attentional and cognitive deficits, delays in motor conduction time, and impairment of specific central nervous system circuits. In 13 healthy volunteers and 20 mildly disabled, relapsing-remitting MS pati...

journal_title：Journal of neurophysiology

authors： Cabib C,Llufriu S,Casanova-Molla J,Saiz A,Valls-Solé J

更新日期：2015-03-01 00:00:00

abstract：:1. Responses to innocuous and noxious mechanical and thermal stimuli were recorded from 90 neurons in the gracile nucleus of anesthetized cats. Cells were tested by antidromic activation for projections to the contralateral ventrobasal thalamus. 2. Cells were characterized broadly by their responses to mechanical stim...

journal_title：Journal of neurophysiology

authors： Cliffer KD,Hasegawa T,Willis WD

更新日期：1992-09-01 00:00:00

abstract：:Flexible behavior requires the ability to delay a response until it is appropriate. This can be achieved by holding either a sensory or a motor representation online. Here we assess whether maintenance of sensory or motor material drives the motor system to different functional states, as indexed by alterations of cor...

journal_title：Journal of neurophysiology

authors： van den Hurk P,Mars RB,van Elswijk G,Hegeman J,Pasman JW,Bloem BR,Toni I

更新日期：2007-02-01 00:00:00

abstract：:Recent studies have shown that sympathetic nervous system (SNS) activity can be heavily impacted not only by basic threats to survival but also by threats to social bonds. In this study we explored the behavioral and physiological consequences of social exclusion/inclusion in patients with psoriasis, a disease frequen...

journal_title：Journal of neurophysiology

authors： Ponsi G,Monachesi B,Panasiti V,Aglioti SM,Panasiti MS

更新日期：2019-01-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:The present study was an examination of state-dependent functional connectivity during spontaneous activity between the piriform cortex and its upstream and downstream connections. Rats were anesthetized with urethan and allowed to spontaneously cycle between fast- and slow-wave states similar to fast- and slow-wave s...

journal_title：Journal of neurophysiology

authors： Wilson DA,Yan X

更新日期：2010-12-01 00:00:00

abstract：:Parkinson's disease is associated with altered neural activity in the motor cortex. Chronic high-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in suppressing parkinsonian motor symptoms and modulates cortical activity. However, the anatomical pathways responsible for STN DBS-medi...

journal_title：Journal of neurophysiology

authors： Kumaravelu K,Oza CS,Behrend CE,Grill WM

更新日期：2018-08-01 00:00:00

abstract：:Sensory-driven behaviors engage a cascade of cortical regions to process sensory input and generate motor output. To investigate the temporal dynamics of neural activity at this global scale, we have improved and integrated tools to perform functional imaging across large areas of cortex using a transgenic mouse expre...

journal_title：Journal of neurophysiology

authors： Wekselblatt JB,Flister ED,Piscopo DM,Niell CM

更新日期：2016-06-01 00:00:00

abstract：:1. We recorded local field potentials in the parafoveal representation in the primary visual cortex of anesthetized and paralyzed macaque monkeys with a multicontact electrode that provided for sampling of neural activity at 16 sites along a vertical penetration. Differential recordings at adjacent contacts were trans...

journal_title：Journal of neurophysiology

authors： Victor JD,Purpura K,Katz E,Mao B

更新日期：1994-11-01 00:00:00

abstract：:Glutamate-receptor-mediated synaptic transmission was studied in morphologically identified hippocampal dentate granule cells (DGCs; n = 31) with the use of whole cell patch-clamp recording and intracellular injection of biocytin or Lucifer yellow in slices prepared from surgically removed medial temporal lobe specime...

journal_title：Journal of neurophysiology

authors： Isokawa M,Levesque M,Fried I,Engel J Jr

更新日期：1997-06-01 00:00:00

abstract：:The caudal primate prefrontal cortex (PFC) is involved in target selection and visually guided saccades through both covert attention and overt orienting eye movements. Unilateral damage to the caudal PFC often leads to decreased awareness of a contralesional target alone, referred to as "neglect," or when it is prese...

journal_title：Journal of neurophysiology

authors： Adam R,Johnston K,Everling S

更新日期：2019-08-01 00:00:00

abstract：:Effective connectivity between cortical areas decreases during slow wave sleep. This decline can be observed in the reduced interareal propagation of activity evoked either directly in cortex by transcranial magnetic stimulation (TMS) or by sensory stimulation. We present here a large-scale model of the thalamocortica...

journal_title：Journal of neurophysiology

authors： Esser SK,Hill S,Tononi G

更新日期：2009-10-01 00:00:00