Abstract:
:It has been suggested that successively presented sounds that are perceived as separate auditory streams are represented by separate populations of neurons. Mostly, spectral separation in different peripheral filters has been identified as the cue for segregation. However, stream segregation based on temporal cues is also possible without spectral separation. Here we present sequences of ABA- triplet stimuli providing only temporal cues to neurons in the European starling auditory forebrain. A and B sounds (125 ms duration) were harmonic complexes (fundamentals 100, 200, or 400 Hz; center frequency and bandwidth chosen to fit the neurons' tuning characteristic) with identical amplitude spectra but different phase relations between components (cosine, alternating, or random phase) and presented at different rates. Differences in both rate responses and temporal response patterns of the neurons when stimulated with harmonic complexes with different phase relations provide first evidence for a mechanism allowing a separate neural representation of such stimuli. Recording sites responding >1 kHz showed enhanced rate and temporal differences compared with those responding at lower frequencies. These results demonstrate a neural correlate of streaming by temporal cues due to the variation of phase that shows striking parallels to observations in previous psychophysical studies.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Itatani N,Klump GMdoi
10.1152/jn.00496.2010subject
Has Abstractpub_date
2011-01-01 00:00:00pages
188-99issue
1eissn
0022-3077issn
1522-1598pii
jn.00496.2010journal_volume
105pub_type
杂志文章abstract::This study of chronic incomplete spinal cord injury (SCI) subjects investigated patterns of central motor drive (i.e., central activation) of the plantar flexors using interpolated twitches, and modulation of soleus H-reflexes during lengthening, isometric, and shortening muscle actions. In a recent study of the knee ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01074.2014
更新日期:2015-07-01 00:00:00
abstract::1. We have studied the responses of neurons in the lateral and descending vestibular nuclei of decerebrate cats to stimulation of neck receptors, produced by rotating the body in vertical planes with the head stationary. The responses to such neck stimulation were compared with the responses to vestibular stimulation ...
journal_title:Journal of neurophysiology
pub_type: 临床试验,杂志文章
doi:10.1152/jn.1988.60.5.1765
更新日期:1988-11-01 00:00:00
abstract::1. The rostromesial agranular frontal cortex of macaque monkey (Macaca fuscata), traditionally defined as the supplementary motor area (SMA), was studied using various physiological techniques to delineate two different areas rostrocaudally. 2. Field and unitary responses to electrical stimulation of the primary motor...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1992.68.3.653
更新日期:1992-09-01 00:00:00
abstract::Despite the peripheral and central immaturities that limit auditory processing in juvenile animals, they are able to lateralize sounds using binaural cues. This study explores a central mechanism that may compensate for these limitations during development. Interaural time and level difference processing by neurons in...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00601.2005
更新日期:2005-12-01 00:00:00
abstract::The rapid detection of sensory inputs is crucial for survival. Sensory detection explicitly requires the integration of incoming sensory information and the ability to distinguish between relevant information and ongoing neural activity. In this study, head-fixed rats were trained to detect the presence of a brief def...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00004.2012
更新日期:2012-07-01 00:00:00
abstract::1. Properties of 90 lateral cervical nucleus (LCN) neurons responsive to light tactile stimulation of ipsilateral body surfaces were examined in pentobarbital sodium-anesthetized raccoons. Peripheral receptive fields (RFs) of 60 of these lay totally or partially on glabrous skin of the forepaw. There were 71 neurons a...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1991.65.6.1411
更新日期:1991-06-01 00:00:00
abstract::1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.6.1966
更新日期:1993-06-01 00:00:00
abstract::Hyolaryngeal elevation is essential for airway protection during swallowing and is mainly a reflexive response to oropharyngeal sensory stimulation. Targeted intramuscular electrical stimulation can elevate the resting larynx and, if applied during swallowing, may improve airway protection in dysphagic patients with i...
journal_title:Journal of neurophysiology
pub_type: 临床试验,杂志文章
doi:10.1152/jn.00025.2005
更新日期:2005-12-01 00:00:00
abstract::In common with other sensory cortices, the mammalian primary auditory cortex (AI) demonstrates the capacity for large-scale reorganization following many experimental situations. For example, training animals in frequency-discrimination tasks has been shown to result in an increase in cortical frequency representation...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.86.4.1555
更新日期:2001-10-01 00:00:00
abstract::We have demonstrated that 4-aminopyridine-3-methanol (4-AP-3-MeOH), a 4-aminopyridine derivative, significantly restores axonal conduction in stretched spinal cord white-matter strips and shows no preference in restoring large and small axons. This compound is 10 times more potent when compared with 4-AP and other der...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00154.2009
更新日期:2010-01-01 00:00:00
abstract::Poststroke pain syndrome (PSPS) is an often intractable disorder characterized by hemiparesis associated with unrelenting chronic pain. Although traditional analgesics have largely failed, integrative approaches targeting affective-cognitive spheres have started to show promise. Recently, we demonstrated that deep bra...
journal_title:Journal of neurophysiology
pub_type: 杂志文章,随机对照试验
doi:10.1152/jn.00830.2017
更新日期:2018-06-01 00:00:00
abstract::In experiments on slices (from 100- to 150-g Sprague-Dawley rats) kept at 33 degreesC, we studied the effects of brief hypoxia (2-3 min) on CA1 neurons. In whole cell recordings from submerged slices, with electrodes containing only KMeSO4 and N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, and in the presence of...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1998.80.5.2378
更新日期:1998-11-01 00:00:00
abstract::The vestibular organs in the base of the skull provide important information about head orientation and motion in space. Previous studies have suggested that both angular velocity information from the semicircular canals and information about head orientation and translation from the otolith organs are centrally proce...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00143.2010
更新日期:2010-09-01 00:00:00
abstract::1. To analyze the selectivity and the sparseness of firing to visual stimuli of single neurons in the primate temporal cortical visual area, neuronal responses were measured to a set of 68 visual stimuli in macaques performing a visual fixation task. The population of neurons analyzed had responses that occurred prima...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1995.73.2.713
更新日期:1995-02-01 00:00:00
abstract::Augmenting (or incremental) responses are progressively growing potentials elicited by 5- to 15-Hz stimulation within the thalamus, cerebral cortex, or by setting into action reciprocal thalamocortical neuronal loops. These responses are associated with short-term plasticity processes in thalamic and cortical neurons....
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1998.79.5.2716
更新日期:1998-05-01 00:00:00
abstract::To explore neural mechanisms how olfactory information is processed in the brain and finally converted into behavior, it would be useful to have isolated whole brains that include both olfactory organs and motor output. In the present study, we identified an in vitro index of odor-evoked behavior in the terrestrial mo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00247.2003
更新日期:2004-01-01 00:00:00
abstract::The recurrent mossy fiber pathway of the dentate gyrus expands dramatically in the epileptic brain and serves as a mechanism for synchronization of granule cell epileptiform activity. It has been suggested that this pathway also promotes epileptiform activity by inhibiting GABA(A) receptor function through release of ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.85.5.1932
更新日期:2001-05-01 00:00:00
abstract::1. Adult rats and rats with a postnatal age of 3-29 days (PN 3-29) were used for the preparation of in vitro slices of the frontal neocortex. Epileptiform activity was induced by bath application of the gamma-aminobutyric acid-A (GABAA) receptor antagonists bicuculline or picrotoxin. 2. The voltage-sensitive dye RH 41...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1994.72.4.1756
更新日期:1994-10-01 00:00:00
abstract::Neuroimaging studies in stroke survivors have suggested that adaptive plasticity occurs following stroke. However, the complex temporal dynamics of neural reorganization after injury make the interpretation of functional imaging studies equivocal. In the present study in adult squirrel monkeys, intracortical microstim...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.90447.2008
更新日期:2008-09-01 00:00:00
abstract::Despite its widespread use, high-resolution imaging with multiphoton microscopy to record neuronal signals in vivo is limited to the surface of brain tissue because of limited light penetration. Moreover, most imaging studies do not simultaneously record electrical neural activity, which is, however, crucial to unders...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00005.2015
更新日期:2015-06-01 00:00:00
abstract::Magnocellular red nucleus (RNm) is involved in controlling goal-directed limb movements such as reaching to grasp. We tested two hypotheses related to RNm's role in controlling reach-to-grasp movements. One hypothesis is that forelimb RNm neurons are grasp specific, and the other is that they specify the timing of met...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00038.2001
更新日期:2002-03-01 00:00:00
abstract::The dorsolateral pontine nucleus (DLPN) and nucleus reticularis tegmenti pontis (NRTP) comprise obligatory links in the cortico-ponto-cerebellar system supporting smooth pursuit eye movements. We examined the response properties of DLPN and rNRTP neurons during step-ramp smooth pursuit of a small target moving across ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00588.2004
更新日期:2005-01-01 00:00:00
abstract::We have previously reported dual effects of mu-opioids on N-methyl-D-aspartate (NMDA)-receptor-mediated synaptic events in the hippocampal dentate gyrus: an indirect facilitating effect via suppression of GABAergic interneurons (disinhibition) and a direct inhibitory effect in the presence of gamma-aminobutyric acid-A...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.78.2.759
更新日期:1997-08-01 00:00:00
abstract::Long-term depression (LTD) was induced in neocortical layer 5 pyramidal connections by pairing presynaptic firing with subthreshold postsynaptic depolarization (dLTD) or via a spike-timing protocol (tLTD). Like tLTD, dLTD reduced short-term depression and increased the coefficient of variation consistent with a presyn...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00376.2004
更新日期:2004-12-01 00:00:00
abstract::To study the possible role of the cerebellum in the vestibular-ocular reflex, extracellular responses of cerebellar nuclear neurons were recorded in awake monkeys during natural vestibular stimulation; 115 neurons in the fastigial nucleus responded to horizontal sinusoidal accelerations applied to the head by means of...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1975.38.3.627
更新日期:1975-05-01 00:00:00
abstract::1. It is widely believed that signals contributing to the receptive field surrounds of retinal bipolar cells pass from horizontal cells to bipolar cells via GABAergic synapses. To test this notion, we applied gamma-aminobutyric acid (GABA) agonists and antagonists to isolated, perfused retinas of the salamander Ambyst...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.76.3.2005
更新日期:1996-09-01 00:00:00
abstract::Intracellular Ca2+ is influenced by both Ca2+ influx and release. We examined intracellular Ca2+ following action potential firing in the bag cell neurons of Aplysia californica. Following brief synaptic input, these neuroendocrine cells undergo an afterdischarge, resulting in elevated Ca2+ and the secretion of neurop...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.90356.2008
更新日期:2008-07-01 00:00:00
abstract::We have recently demonstrated that application of the mustard oil (MO), a small-fiber excitant and inflammatory irritant, to the rat maxillary molar tooth pulp induces significant increases in jaw muscle electromyographic (EMG) activity and neuroplastic changes in trigeminal (V) subnucleus caudalis. Since subnucleus o...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.85.5.1836
更新日期:2001-05-01 00:00:00
abstract::1. Mechanisms of depolarizing synaptic inhibition were investigated at the crayfish giant motor synapse with the use of two-electrode current- and voltage-clamp techniques. Depolarizing inhibitory postsynaptic potentials (d-IPSPs) of between 5 and 15 mV in amplitude are produced there in the motor giant motoneuron (Mo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1990.64.2.532
更新日期:1990-08-01 00:00:00
abstract::For human locomotion, varying environments require adjustments of the motor system. We asked whether age affects gait balance recovery adaptation, its retention over months, and the transfer of adaptation to an untrained reactive balance task. Healthy adults (26 young, 27 middle-aged, and 25 older; average ages 24, 52...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00380.2019
更新日期:2019-11-01 00:00:00