Endocannabinoid-dependent neocortical layer-5 LTD in the absence of postsynaptic spiking.

abstract：:The mechanism(s) of olfactory transduction in invertebrates remains to be fully understood. In lobster olfactory receptor neurons (ORNs), a nonselective sodium-gated cation (SGC) channel, a presumptive transient receptor potential (TRP)C channel homolog, plays a crucial role in olfactory transduction, at least in part...

journal_title：Journal of neurophysiology

authors： Pezier A,Bobkov YV,Ache BW

更新日期：2009-03-01 00:00:00

abstract：:Although understanding the processing of natural sounds is an important goal in auditory neuroscience, relatively little is known about the neural coding of these sounds. Recently we demonstrated that the spectral temporal receptive field (STRF), a description of the stimulus-response function of auditory neurons, cou...

journal_title：Journal of neurophysiology

authors： Sen K,Theunissen FE,Doupe AJ

更新日期：2001-09-01 00:00:00

abstract：:We have studied how rewards modulate the occurrence of microsaccades by manipulating the size of an expected reward and the location of the cue that sets the expectations for future reward. We found an interaction between the size of the reward and the location of the cue. When monkeys fixated on a cue that signaled t...

journal_title：Journal of neurophysiology

authors： Joshua M,Tokiyama S,Lisberger SG

更新日期：2015-11-01 00:00:00

abstract：:We compared electroretinographic (ERG) responses to uniform-field and a variety of pattern stimuli using both transient and steady-state analyses. Evidence is provided that for all of these stimuli, the peak at high temporal frequencies in the steady-state response corresponds to the fast wave of the transient respons...

journal_title：Journal of neurophysiology

authors： Baker CL Jr,Hess RF

更新日期：1984-05-01 00:00:00

abstract：:Pharmacological modulation of gamma-aminobutyric acid-A (GABAA) receptors can provide important information on the types of subunits composing these receptors. In recombinant studies, zinc more potently inhibits alphabeta subunits compared with the alphabetagamma combination, whereas modulation by nanomolar concentrat...

journal_title：Journal of neurophysiology

authors： Defazio T,Hablitz JJ

更新日期：1998-10-01 00:00:00

abstract：:The effect of peripheral lesions on cerebral somatosensory representations is well studied for experimentally induced amputations and deafferentations acquired later in life. However, few studies have investigated the brain's capacity for plastic changes in congenital malformations. We studied somatosensory-evoked fie...

journal_title：Journal of neurophysiology

authors： Stoeckel MC,Pollok B,Witte OW,Seitz RJ,Schnitzler A

更新日期：2005-02-01 00:00:00

abstract：:Such perisaccadic mislocalization is maximal in the direction of the saccade and varies systematically with the target-saccade onset delay. We have recently shown that under head-fixed conditions perisaccadic errors do not follow the quantitative predictions of current visuomotor models that explain these mislocalizat...

journal_title：Journal of neurophysiology

authors： van Wetter SM,van Opstal AJ

更新日期：2008-10-01 00:00:00

abstract：:Sleep disturbances are prevalent in clinical anxiety, but it remains unclear whether they are cause and/or consequence of this condition. Fear conditioning constitutes a valid laboratory model for the acquisition of normal and pathological anxiety. To explore the relationship between disturbed sleep and anxiety in mor...

journal_title：Journal of neurophysiology

authors： Peters AC,Blechert J,Sämann PG,Eidner I,Czisch M,Spoormaker VI

更新日期：2014-09-15 00:00:00

abstract：:Cellular mechanisms underlying learning and memory were investigated in the octopus using a brain slice preparation of the vertical lobe, an area of the octopus brain involved in learning and memory. Field potential recordings revealed long-term potentiation (LTP) of glutamatergic synaptic field potentials similar to ...

journal_title：Journal of neurophysiology

authors： Hochner B,Brown ER,Langella M,Shomrat T,Fiorito G

更新日期：2003-11-01 00:00:00

abstract：:Inhibition is presumed to play an important role in gustatory processing in the rostral nucleus of the solitary tract (rNST). One source of inhibition, GABA, is abundant within the nucleus and comes both from local, intrasolitary sources and from outside the nucleus. In addition to the receptor-mediated effects of GAB...

journal_title：Journal of neurophysiology

authors： Chen Z,Travers SP,Travers JB

更新日期：2016-08-01 00:00:00

abstract：:Modularity in the central nervous system (CNS), i.e., the brain capability to generate a wide repertoire of movements by combining a small number of building blocks ("modules"), is thought to underlie the control of movement. Numerous studies reported evidence for such a modular organization by identifying invariant m...

journal_title：Journal of neurophysiology

authors： Delis I,Panzeri S,Pozzo T,Berret B

更新日期：2014-02-01 00:00:00

abstract：:Activity-dependent developmental maturation of the neocortical network is thought to involve the stabilization and potentiation of immature synapses. In particular, N-methyl-d-aspartate (NMDA) receptor-dependent long-term plasticity that is expressed presynaptically appears to be crucial for the selection of functiona...

journal_title：Journal of neurophysiology

authors： Walz C,Jüngling K,Lessmann V,Gottmann K

更新日期：2006-12-01 00:00:00

abstract：:In many rhythmic neuronal networks that operate in a wide range of frequencies, the time of neuronal firing relative to the cycle period (the phase) is invariant. This invariance suggests that when frequency changes, firing time is precisely adjusted either by intrinsic or synaptic mechanisms. We study the maintenance...

journal_title：Journal of neurophysiology

authors： Manor Y,Bose A,Booth V,Nadim F

更新日期：2003-11-01 00:00:00

abstract：:In quadrupeds, the dorsal-side-up body orientation during standing is maintained due to a postural system that is driven by feedback signals coming mainly from limb mechanoreceptors. In caudally decerebrated (postmammillary) rabbits, the efficacy of this system is considerably reduced. In this paper, we report that th...

journal_title：Journal of neurophysiology

authors： Zelenin PV,Hsu LJ,Orlovsky GN,Deliagina TG

更新日期：2012-06-01 00:00:00

abstract：:Extraretinal information, such as corollary discharge (CD), is hypothesized to help compensate for saccade-induced visual input disruptions. However, support for this hypothesis is largely for one-dimensional transsaccadic visual changes, with little comprehensive information on the spatial characteristics. Here we sy...

journal_title：Journal of neurophysiology

authors： Jayet Bray LC,Bansal S,Joiner WM

更新日期：2016-03-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:Unitary discharge patterns (peristimulus time histograms or PSTH) and synaptic events were studies with intracellular recording techniques in 164 cat cochlear nucleus cells to steady-frequency tone bursts 250 ms in duration. There were four response types defined on the basis of the shape of the discharge patterns to ...

journal_title：Journal of neurophysiology

authors： Britt R,Starr A

更新日期：1976-01-01 00:00:00

abstract：:We investigated adaptation to simple force field scaling to determine whether the same strategy is used as during adaptation to more complex changes in the mechanical environment. Subjects initially trained in a force field, consisting of a rightward lateral force with a parabolic spatial profile (PF). The field stren...

journal_title：Journal of neurophysiology

authors： Hinder MR,Milner TE

更新日期：2007-11-01 00:00:00

abstract：:Many neurons in the dorsal region of the medial superior temporal area (MSTd) of monkey cerebral cortex respond to optic flow stimuli in which the center of motion is shifted off the center of the visual field. Each shifted-center-of-motion stimulus presents both different directions of planar motion throughout the vi...

journal_title：Journal of neurophysiology

authors： Duffy CJ,Wurtz RH

更新日期：1997-02-01 00:00:00

abstract：:The medial superior temporal area of the macaque monkey extrastriate visual cortex can be divided into a dorsal medial (MSTd) and a lateral ventral (MSTl) region. The functions of the two regions may not be identical: MSTd may process optic flow information that results from the movement of the observer, whereas MSTl ...

journal_title：Journal of neurophysiology

authors： Eifuku S,Wurtz RH

更新日期：1998-07-01 00:00:00

abstract：:Orexin-producing neurons are clearly essential for the regulation of wakefulness and sleep because loss of these cells produces narcolepsy. However, little is understood about how these neurons dynamically interact with other wake- and sleep-regulatory nuclei to control behavioral states. Using survival analysis of wa...

journal_title：Journal of neurophysiology

authors： Diniz Behn CG,Kopell N,Brown EN,Mochizuki T,Scammell TE

更新日期：2008-06-01 00:00:00

abstract：:Behavioral studies have shown that object recognition becomes severely impaired at fast presentation rates, indicating a limitation in temporal processing capacity. Here, we studied whether this behavioral limit in object recognition reflects limitations in the temporal processing capacity of early visual areas tuned ...

journal_title：Journal of neurophysiology

authors： McKeeff TJ,Remus DA,Tong F

更新日期：2007-07-01 00:00:00

abstract：:Generalizing newly learned movement patterns beyond the training context is challenging for most motor learning situations. Here we tested whether learning of a new physical property of the arm during self-initiated reaching generalizes to new arm configurations. Human participants performed a single-joint elbow reach...

journal_title：Journal of neurophysiology

authors： Maeda RS,Zdybal JM,Gribble PL,Pruszynski JA

更新日期：2020-03-01 00:00:00

abstract：:1. Responses of primary sensory neurons to substance P applications by perfusion were studied with intracellular recording techniques in in vitro slice preparations of trigeminal root ganglia (guinea pigs). Application of substance P in micromolar doses produced reversible depolarizations of 2-47 mV in 48 out of 64 ne...

journal_title：Journal of neurophysiology

authors： Spigelman I,Puil E

更新日期：1990-07-01 00:00:00

abstract：:Glycinergic and GABAergic inhibition are juxtaposed at one retinal synaptic layer yet likely perform different functions. These functions have usually been evaluated using receptor antagonists. In examining retinal glycine receptors, we were surprised to find that commonly used concentrations of GABA antagonists block...

journal_title：Journal of neurophysiology

authors： Wang P,Slaughter MM

更新日期：2005-06-01 00:00:00

abstract：:1. The effects of the di- and trivalent trace metal cations, Pb2+, Zn2+, and Al3+, on voltage-activated calcium channel currents recorded from cultured rat dorsal root ganglion neurons were determined. 2. All three cations blocked transient and sustained components of the voltage-gated calcium channel currents elicite...

journal_title：Journal of neurophysiology

authors： Büsselberg D,Platt B,Michael D,Carpenter DO,Haas HL

更新日期：1994-04-01 00:00:00

abstract：:The distribution of functional neurotransmitter receptors is an important determinant of neuronal information processing. To map the location of functional glutamate and GABA receptors on individual hippocampal neurons, we photolyzed "caged" glutamate and GABA while measuring the electrical currents resulting from act...

journal_title：Journal of neurophysiology

authors： Pettit DL,Augustine GJ

更新日期：2000-07-01 00:00:00

abstract：:1. A quantitative analysis of facilitation during the kindling stimulation to the amygdala was conducted by measuring the area between the excitatory potential and the baseline in the averaged tetanic response recorded at the entorhinal cortex. The changes in facilitation were then compared with the development of ele...

journal_title：Journal of neurophysiology

authors： Matsuura S,Hirayama K,Murata R

更新日期：1993-08-01 00:00:00

abstract：:Mechanisms of direction selectivity and speed selectivity were studied in single neurons of the middle temporal visual area (MT) of behaving macaque monkeys. Visual stimuli were presented in both smooth and stroboscopic motion within a neuron's receptive field as the monkey fixated a stationary point of light. Directi...

journal_title：Journal of neurophysiology

authors： Mikami A,Newsome WT,Wurtz RH

更新日期：1986-06-01 00:00:00

abstract：:1. Surgically resected tissue from the tip of the human temporal lobe of seven patients undergoing temporal lobectomy was employed to study functional properties of GABAergic inhibition mediated through activation of GABAA receptors, using patch-clamp recording techniques in acutely isolated neurons and in slices of h...

journal_title：Journal of neurophysiology

authors： Gibbs JW 3rd,Zhang YF,Kao CQ,Holloway KL,Oh KS,Coulter DA

更新日期：1996-04-01 00:00:00