Abstract:
:1. The statistical properties of the bursting potassium channel from fused Torpedo synaptosomes were studied by using patch-clamp recording and time series analysis. 2. Voltage steps produce channel openings; the number of channels opening fluctuates from trial to trial. The maximal current observed in each trial is strongly dependent on the previous history of the membrane patch. Trials with no activity are frequently clumped together and so are trials with intense activity. 3. Autocorrelation analysis reveals a strong interdependence of successive responses, which is voltage dependent. 4. We propose that the strong statistical interdependence of responses to successive depolarizing pulses (the statistical "memory") is a manifestation of a long lived closed state. We speculate that this statistical memory may be of significance in frequency modulation of transmitter release.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Rahamimoff R,Edry-Schiller J,Ginsburg Sdoi
10.1152/jn.1992.68.6.2260subject
Has Abstractpub_date
1992-12-01 00:00:00pages
2260-3issue
6eissn
0022-3077issn
1522-1598journal_volume
68pub_type
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journal_title:Journal of neurophysiology
pub_type: 杂志文章
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更新日期:2014-08-15 00:00:00
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journal_title:Journal of neurophysiology
pub_type: 杂志文章
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更新日期:2009-10-01 00:00:00
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journal_title:Journal of neurophysiology
pub_type: 杂志文章
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更新日期:1994-06-01 00:00:00
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journal_title:Journal of neurophysiology
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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