Quantifying the magnitude of changes in synaptic level parameters with long-term potentiation.

abstract：:Differential Modulation by Copper and Zinc of P2X2 and P2X4 Receptor Function. The modulation by Cu2+ and Zn2+ of P2X2 and P2X4 receptors expressed in Xenopus oocytes was studied with the two-electrode, voltage-clamp technique. In oocytes expressing P2X2 receptors, both Cu2+ and Zn2+, in the concentration range 1-130 ...

journal_title：Journal of neurophysiology

authors： Xiong K,Peoples RW,Montgomery JP,Chiang Y,Stewart RR,Weight FF,Li C

更新日期：1999-05-01 00:00:00

abstract：:Foot drop is very common among people with chronic incomplete spinal cord injury (SCI) and likely stems from SCI that disturbs the corticospinal activation of the ankle dorsiflexor tibialis anterior (TA). Thus, if one can recover or increase the corticospinal excitability reduced by SCI, motor function recovery may be...

journal_title：Journal of neurophysiology

authors： Thompson AK,Fiorenza G,Smyth L,Favale B,Brangaccio J,Sniffen J

更新日期：2019-03-01 00:00:00

abstract：:The innervation patterns of vestibular saccular afferents were quantitatively investigated in pigeons using biotinylated dextran amine as a neural tracer and three-dimensional computer reconstruction. Type I hair cells were found throughout a large portion of the macula, with the highest density observed in the striol...

journal_title：Journal of neurophysiology

authors： Zakir M,Huss D,Dickman JD

更新日期：2003-01-01 00:00:00

abstract：:Thalamic intralaminar and medial nuclei participate mainly in affective and motivational aspects of pain processing. Unique to the present study were identification and characterization of spontaneously active neurons in the central lateral nucleus (CL) of the intralaminar thalamus, which were found to respond only to...

journal_title：Journal of neurophysiology

authors： Ren Y,Zhang L,Lu Y,Yang H,Westlund KN

更新日期：2009-07-01 00:00:00

abstract：:1. The active stiffness of ventral superficial abdominal muscle (VSM) of the hermit crab, Pagurus pollicarus, was measured with ramp stretches of different amplitudes and velocities. Active stiffness was calculated by subtracting the peak force produced by passive stretch and the isometric force just before stretch fr...

journal_title：Journal of neurophysiology

authors： Chapple WD

更新日期：1989-11-01 00:00:00

abstract：:During walking, maintenance and coordination of activity in leg motoneurons requires intersegmental signal transfer. In a semi-intact preparation of the stick insect, we studied membrane potential modulations in mesothoracic (middle leg) motoneurons and local premotor nonspiking interneurons that were induced by stepp...

journal_title：Journal of neurophysiology

authors： Ludwar BCh,Westmark S,Büschges A,Schmidt J

更新日期：2005-10-01 00:00:00

abstract：:1. Voltage-dependent K+ currents were studied in normal rat anterior pituitary cells using the patch-clamp technique. To obtain cultures enriched for lactotrophs, density gradient centrifugation was performed on pituitary cells isolated from lactating rats. 2. Depolarizations to about -30 mV from a holding potential o...

journal_title：Journal of neurophysiology

authors： Herrington J,Lingle CJ

更新日期：1994-08-01 00:00:00

abstract：:1. Movement of the crayfish thoracocoxal leg joint is monitored by a muscle receptor organ (TCMRO) and a chordotonal organ (TCCO). Both receptors span the joint in parallel but signal opposite directions of leg movement. The TCMRO is innervated by afferents responsive to lengthening, which corresponds to leg remotion,...

journal_title：Journal of neurophysiology

authors： Skorupski P,Rawat BM,Bush BM

更新日期：1992-03-01 00:00:00

abstract：:6-((4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl)amino)hexanoic acid ryanodine (BODIPY-ryanodine) binding and Ca(2+) imaging were used to study the properties of ryanodine receptors (RyRs) and cytoplasmic Ca(2+) (Ca) changes in neurons cultured from the embryonic rat hippocampus during the earli...

journal_title：Journal of neurophysiology

authors： Sukhareva M,Smith SV,Maric D,Barker JL

更新日期：2002-09-01 00:00:00

abstract：:The magnitude of postsynaptic Ca(2+) transients is thought to affect activity-dependent synaptic plasticity associated with learning and memory. Large Ca(2+) transients have been implicated in the induction of long-term potentiation (LTP), while smaller Ca(2+) transients have been associated with long-term depression ...

journal_title：Journal of neurophysiology

authors： Cormier RJ,Greenwood AC,Connor JA

更新日期：2001-01-01 00:00:00

abstract：:Spontaneous and stimulus-evoked excitatory postsynaptic currents (EPSCs) were recorded in calyx nerve terminals from the turtle vestibular lagena to quantify key attributes of quantal transmission at this synapse. On average, EPSC events had a magnitude of ∼ 42 pA, a rise time constant of τ(0) ∼ 229 μs, decayed to bas...

journal_title：Journal of neurophysiology

authors： Highstein SM,Mann MA,Holstein GR,Rabbitt RD

更新日期：2015-06-01 00:00:00

abstract：:1. Teased axon recordings were made from 167 spontaneously active A beta- and A delta-afferents that ended in sciatic nerve end neuromas of 6-12 days standing. When challenged with a standard bolus of systemically applied adrenaline, 100 (60%) responded, either with an increase in baseline firing frequency (excitation...

journal_title：Journal of neurophysiology

authors： Chen Y,Michaelis M,Janig W,Devor M

更新日期：1996-12-01 00:00:00

abstract：:1. The kinetic properties of embryonic Xenopus spinal cord neuron N-methyl-D-aspartate (NMDA)-activated receptors (NMDAR) were examined at the single-channel level. These receptors have a main conductance state of 50 pS and make occasional sojourns to a subconductance level of approximately 40 pS. The open channel lif...

journal_title：Journal of neurophysiology

authors： Zhang Y,Auerbach A

更新日期：1995-07-01 00:00:00

abstract：:We have addressed the source and nature of the persistent neural activity that bridges the stimulus-free gap between the conditioned stimulus (CS) and unconditioned stimulus (US) during trace eyelid conditioning. Previous work has demonstrated that this persistent activity is necessary for trace eyelid conditioning: C...

journal_title：Journal of neurophysiology

authors： Siegel JJ,Kalmbach B,Chitwood RA,Mauk MD

更新日期：2012-01-01 00:00:00

abstract：:In this study, we examined the effect of arachidonic acid (AA) on the BK alpha-subunit with or without beta-subunits expressed in Xenopus oocytes. In excised patches, AA potentiated the hSlo-alpha current and slowed inactivation only when beta2/3 subunit was co-expressed. The beta2-subunit-dependent modulation by AA p...

journal_title：Journal of neurophysiology

authors： Sun X,Zhou D,Zhang P,Moczydlowski EG,Haddad GG

更新日期：2007-01-01 00:00:00

abstract：:Autoinhibitory serotonin 1A receptors (5-HT(1A)) in dorsal raphé nucleus (DRN) have been implicated in chronic depression and in actions of selective serotonin reuptake inhibitors (SSRI). Due to experimental limitations, it was never studied at single-cell level whether changes in 5-HT(1A) receptor functionality occur...

journal_title：Journal of neurophysiology

authors： Cornelisse LN,Van der Harst JE,Lodder JC,Baarendse PJ,Timmerman AJ,Mansvelder HD,Spruijt BM,Brussaard AB

更新日期：2007-07-01 00:00:00

abstract：:Searching for items that are useful given current goals, or "target" recognition, requires observers to flexibly attend to certain object properties at the expense of others. This could involve focusing on the identity of an object while ignoring identity-preserving transformations such as changes in viewpoint or focu...

journal_title：Journal of neurophysiology

authors： Henderson M,Serences JT

更新日期：2019-04-01 00:00:00

abstract：:1. The action of N-methyl-D-aspartate (NMDA) on cone horizontal cells was studied in in vitro goldfish retinas superfused with a bicarbonate-based Ringer solution that contained D-serine (0.5 microM), a glycine analogue, but no added Mg2+. Horizontal cell light responses and electrical coupling were assessed by monito...

journal_title：Journal of neurophysiology

authors： Harsanyi K,Wang Y,Mangel SC

更新日期：1996-02-01 00:00:00

abstract：:How the CNS masters the many degrees of freedom of the musculoskeletal system to control goal-directed movements is a long-standing question. We have recently provided support to the hypothesis that the CNS relies on a modular control architecture by showing that the phasic muscle patterns for fast reaching movements ...

journal_title：Journal of neurophysiology

authors： d'Avella A,Fernandez L,Portone A,Lacquaniti F

更新日期：2008-09-01 00:00:00

abstract：:1. Visual attention is often profoundly disturbed in humans after damage to the cortex of the posterior parietal lobe, particularly of the minor hemisphere, with some patients being totally unaware of visual stimuli in the hemifield of extrapersonal space contralateral to the cortical damage. This severe form of visua...

journal_title：Journal of neurophysiology

authors： Lynch JC,McLaren JW

更新日期：1989-01-01 00:00:00

abstract：:Reach-to-grasp movements require information about the distance and size of target objects. Calibration of this information could be achieved via feedback information (visual and/or haptic) regarding terminal accuracy when target objects are grasped. A number of reports suggest that the nervous system alters reach-to-...

journal_title：Journal of neurophysiology

authors： Bingham GP,Mon-Williams MA

更新日期：2013-12-01 00:00:00

abstract：:The problem of how the hippocampus encodes both spatial and nonspatial information at the cellular network level remains largely unresolved. Spatial memory is widely modeled through the theoretical framework of attractor networks, but standard computational models can only represent spaces that are much smaller than t...

journal_title：Journal of neurophysiology

authors： Hedrick KR,Zhang K

更新日期：2016-08-01 00:00:00

abstract：:When an object is lifted vertically, the normal force increases and decreases in tandem with tangential (load) force to safely avoid slips. For horizontal object transport, horizontal forces at the contact surfaces can be decomposed into manipulation forces (producing acceleration/deceleration) and grasping forces. Al...

journal_title：Journal of neurophysiology

authors： Winges SA,Soechting JF,Flanders M

更新日期：2007-08-01 00:00:00

abstract：:1. Behavioral studies in the monkey and clinical studies in humans show that some visuomotor functions are spared in case of a V1 lesion. This residual vision appears to be subserved at least partially by visual activity in extrastriate cortex. Earlier studies have demonstrated that neurons in area V2 lose their visua...

journal_title：Journal of neurophysiology

authors： Girard P,Salin PA,Bullier J

更新日期：1991-11-01 00:00:00

abstract：:Several studies have demonstrated that motor adaptations to a novel task environment can be transferred between limbs. Such interlimb transfer of motor commands is consistent with the notion of centrally driven strategies that can be generalized across different frames of reference. So far, studies of interlimb transf...

journal_title：Journal of neurophysiology

authors： Houldin A,Chua R,Carpenter MG,Lam T

更新日期：2012-08-01 00:00:00

abstract：:1. Extracellular and intracellular recordings from an isolated thoraco-abdominal preparation of the crayfish, Pacifastacus leniusculus, demonstrate that the swimmeret and the abdominal positioning systems can at times be spontaneously coordinated with each other. 2. Two forms of coordination were encountered between t...

journal_title：Journal of neurophysiology

authors： Chrachri A,Neil DM

更新日期：1993-05-01 00:00:00

abstract：:Although it is generally accepted that humans cannot perceive sounds in the frequency range above 20 kHz, the question of whether the existence of such "inaudible" high-frequency components may affect the acoustic perception of audible sounds remains unanswered. In this study, we used noninvasive physiological measure...

journal_title：Journal of neurophysiology

authors： Oohashi T,Nishina E,Honda M,Yonekura Y,Fuwamoto Y,Kawai N,Maekawa T,Nakamura S,Fukuyama H,Shibasaki H

更新日期：2000-06-01 00:00:00

abstract：:1. Biventer cervicis (BC) is an anatomically complex muscle that is divided by tendinous inscriptions into five in-series compartments of motor units. We have analyzed the fiber architecture and fiber-type composition of these different compartments using microdissection and histochemical methods. 2. BC narrows as it ...

journal_title：Journal of neurophysiology

authors： Richmond FJ,Armstrong JB

更新日期：1988-07-01 00:00:00

abstract：:Whole cell membrane currents induced by the inflammatory mediators, bradykinin, 5-hydroxytryptamine (5-HT) and prostaglandin E2, were investigated in capsaicin-sensitive dorsal root ganglion (DRG) neurons from newborn rats grown on a monolayer of hippocampal glia without nerve growth factor (NGF). When firmly attached...

journal_title：Journal of neurophysiology

authors： Vyklický L,Knotková-Urbancová H,Vitásková Z,Vlachová V,Kress M,Reeh PW

更新日期：1998-02-01 00:00:00

abstract：:The study of quadrupeds has furnished most of our understanding of mammalian locomotion. To allow a more direct comparison of coordination between the four limbs in humans and quadrupeds, we studied crawling in the human, a behavior that is part of normal human development and mechanically more similar to quadrupedal ...

journal_title：Journal of neurophysiology

authors： Patrick SK,Noah JA,Yang JF

更新日期：2009-02-01 00:00:00