The effects of expectancy on corticospinal excitability: passively preparing to observe a movement.

Abstract:

:The corticospinal tract excitability is modulated when preparing movements. Earlier to movement execution, the excitability of the spinal cord increases waiting for supraspinal commands to release the movement. Movement execution and movement observation share processes within the motor system, although movement observation research has focused on processes later to movement onset. We used single and paired pulse transcranial magnetic stimulation on M1 (n = 12), and electrical cervicomedullary stimulation (n = 7), to understand the modulation of the corticospinal system during the "preparation" to observe a third person's movement. Subjects passively observed a hand that would remain still or make an index finger extension. The observer's corticospinal excitability rose when "expecting to see a movement" vs. when "expecting to see a still hand." The modulation took origin at a spinal level and not at the corticocortical networks explored. We conclude that expectancy of seeing movements increases the excitability of the spinal cord.

journal_name

J Neurophysiol

authors

Arias P,Robles-García V,Espinosa N,Corral-Bergantiños Y,Mordillo-Mateos L,Grieve K,Oliviero A,Cudeiro J

doi

10.1152/jn.00353.2013

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

1479-86

issue

7

eissn

0022-3077

issn

1522-1598

pii

jn.00353.2013

journal_volume

111

pub_type

杂志文章
  • Postnatal development of the motor representation in primary motor cortex.

    abstract::The purpose of this study was to examine when the muscles and joints of the forelimb become represented in primary motor cortex (M1) during postnatal life and how local representation patterns change. We examined these questions in cats that were anesthetized (45-90 days, n = 14; adults, n = 3) and awake (n = 4; 52-86...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2000.84.5.2582

    authors: Chakrabarty S,Martin JH

    更新日期:2000-11-01 00:00:00

  • Intracortical circuits in rat anterior cingulate cortex are activated by nociceptive inputs mediated by medial thalamus.

    abstract::We investigated the afferents and intracortical synaptic organization of the anterior cingulate cortex (ACC) during noxious electrical stimulation. Extracellular field potentials were recorded simultaneously from 16 electrodes spanning all layers of the ACC in male Sprague-Dawley rats anesthetized by halothane inhalat...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00623.2006

    authors: Yang JW,Shih HC,Shyu BC

    更新日期:2006-12-01 00:00:00

  • Megamap: flexible representation of a large space embedded with nonspatial information by a hippocampal attractor network.

    abstract::The problem of how the hippocampus encodes both spatial and nonspatial information at the cellular network level remains largely unresolved. Spatial memory is widely modeled through the theoretical framework of attractor networks, but standard computational models can only represent spaces that are much smaller than t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00856.2015

    authors: Hedrick KR,Zhang K

    更新日期:2016-08-01 00:00:00

  • Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats.

    abstract::Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats. J. Neurophysiol. 78: 2388-2395, 1997. Several neurotransmitters have been reported to play important roles in the chemoreception of the carotid body. Among them acetylcholine (ACh) appears to be involved in excitatory processe...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.78.5.2388

    authors: Shirahata M,Fitzgerald RS,Sham JS

    更新日期:1997-11-01 00:00:00

  • Auditory nerve fibers excite targets through synapses that vary in convergence, strength, and short-term plasticity.

    abstract::Auditory nerve fibers are the major source of excitation to the three groups of principal cells of the ventral cochlear nucleus (VCN), bushy, T stellate, and octopus cells. Shock-evoked excitatory postsynaptic currents (eEPSCs) in slices from mice showed systematic differences between groups of principal cells, indica...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00451.2010

    authors: Cao XJ,Oertel D

    更新日期:2010-11-01 00:00:00

  • A long closed state of the synaptosomal bursting potassium channel confers a statistical memory.

    abstract::1. The statistical properties of the bursting potassium channel from fused Torpedo synaptosomes were studied by using patch-clamp recording and time series analysis. 2. Voltage steps produce channel openings; the number of channels opening fluctuates from trial to trial. The maximal current observed in each trial is s...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.6.2260

    authors: Rahamimoff R,Edry-Schiller J,Ginsburg S

    更新日期:1992-12-01 00:00:00

  • Bilateral saccadic deficits following large and reversible inactivation of unilateral frontal eye field.

    abstract::Inactivation permits direct assessment of the functional contribution of a given brain area to behavior. Previous inactivation studies of the frontal eye field (FEF) have either used large permanent ablations or reversible pharmacological techniques that only inactivate a small volume of tissue. Here we evaluated the ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00398.2013

    authors: Peel TR,Johnston K,Lomber SG,Corneil BD

    更新日期:2014-01-01 00:00:00

  • Effects of cerebral neuron C-PR on body postural muscles associated with a food-induced arousal state in Aplysia.

    abstract::1. Firing of cerebral neuron, C-PR, produced complex bilateral movements of various regions of the body of the marine mollusc Aplysia californica. The movements were similar to those seen when the animal assumes the head-up feeding posture during food-induced arousal. Muscles of the neck largely contracted in transver...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.3.1231

    authors: Nagahama T,Weiss KR,Kupfermann I

    更新日期:1993-09-01 00:00:00

  • Calcium-independent depolarization-activated potassium currents in superior colliculus-projecting rat visual cortical neurons.

    abstract::1. K+ conductances were characterized in isolated, identified superior colliculus-projecting (SCP) rat visual cortical neurons. SCP neurons were identified in vitro under epifluorescence illumination after in vivo retrograde labeling with rhodamine-labeled microspheres or "beads." For experiments, SCP neurons were iso...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.73.6.2163

    authors: Albert JL,Nerbonne JM

    更新日期:1995-06-01 00:00:00

  • Dynamics of receptive field size in primary visual cortex.

    abstract::Recent studies have shown that the initial responses evoked by a stimulus in neurons of primary visual cortex are dominated by low spatial frequency information in the image, whereas finer spatial scales dominate later in the response. Such phenomena could arise from the dynamics of receptive field (RF) size at early ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00830.2006

    authors: Malone BJ,Kumar VR,Ringach DL

    更新日期:2007-01-01 00:00:00

  • Time course of locomotor recovery and functional regeneration in spinal cord-transected lamprey: in vitro preparations.

    abstract::1. Previous studies indicate that after transection of the rostral spinal cord, larval lamprey begin to recover locomotor behavior 2 wk posttransection and recovery is complete at approximately 8 wk. To examine the mechanisms underlying behavioral recovery after spinal cord transection, in the present study the time c...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.72.2.847

    authors: McClellan AD

    更新日期:1994-08-01 00:00:00

  • Shared and private variability in the auditory cortex.

    abstract::The high variability of cortical sensory responses is often assumed to impose a major constraint on efficient computation. In the auditory cortex, however, response variability can be very low. We have used in vivo whole cell patch-clamp methods to study the trial-to-trial variability of the subthreshold fluctuations ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00197.2004

    authors: Deweese MR,Zador AM

    更新日期:2004-09-01 00:00:00

  • Zinc and zolpidem modulate mIPSCs in rat neocortical pyramidal neurons.

    abstract::Pharmacological modulation of gamma-aminobutyric acid-A (GABAA) receptors can provide important information on the types of subunits composing these receptors. In recombinant studies, zinc more potently inhibits alphabeta subunits compared with the alphabetagamma combination, whereas modulation by nanomolar concentrat...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.80.4.1670

    authors: Defazio T,Hablitz JJ

    更新日期:1998-10-01 00:00:00

  • Fatigue of paralyzed and control thenar muscles induced by variable or constant frequency stimulation.

    abstract::Muscles paralyzed by chronic (>1 yr) spinal cord injury fatigue readily. Our aim was to evaluate whether the fatigability of paralyzed thenar muscles (n = 10) could be reduced by the repeated delivery of variable versus constant frequency pulse trains. Fatigue was induced in four ways. Intermittent supramaximal median...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01002.2002

    authors: Thomas CK,Griffin L,Godfrey S,Ribot-Ciscar E,Butler JE

    更新日期:2003-04-01 00:00:00

  • SA1 and RA receptive fields, response variability, and population responses mapped with a probe array.

    abstract::Twenty-four slowly adapting type 1 (SA1) and 26 rapidly adapting (RA) cutaneous mechanoreceptive afferents in the rhesus monkey were studied with an array of independently controlled, punctate probes that covered an entire fingerpad. Each afferent had a receptive field (RF) on a single fingerpad and was studied at 73 ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.81.6.2701

    authors: Vega-Bermudez F,Johnson KO

    更新日期:1999-06-01 00:00:00

  • Reduced voltage-dependent Ca2+ signaling in CA1 neurons after brief ischemia in gerbils.

    abstract::An initial overload of intracellular Ca2+ plays a critical role in the delayed death of hippocampal CA1 neurons that die a few days after transient ischemia. Without direct evidence, the prevailing hypothesis has been that Ca2+ overload may recur until cell death. Here, we report the first measurements of intracellula...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.81.1.299

    authors: Connor JA,Razani-Boroujerdi S,Greenwood AC,Cormier RJ,Petrozzino JJ,Lin RC

    更新日期:1999-01-01 00:00:00

  • Influence of vagotomy on monosynaptic transmission at second-order nucleus tractus solitarius synapses.

    abstract::Manipulations of vagal activity are used to treat medical pathologies, but the underlying CNS changes caused by these treatments are not well understood. Furthermore, heart and lung transplant as well as treatments for many gastrointestinal disorders result in section of the vagus nerve (vagotomy). Following unilatera...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00168.2009

    authors: Swartz JB,Weinreich D

    更新日期:2009-11-01 00:00:00

  • Parvalbumin-deficiency facilitates repetitive IPSCs and gamma oscillations in the hippocampus.

    abstract::In the hippocampus, the calcium-binding protein parvalbumin (PV) is expressed in interneurons that innervate perisomatic regions. PV in GABAergic synaptic terminals was proposed to limit repetitive GABA release by buffering of "residual calcium." We assessed the role of presynaptic PV in Ca(2+)-dependent GABA release ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00576.2002

    authors: Vreugdenhil M,Jefferys JG,Celio MR,Schwaller B

    更新日期:2003-03-01 00:00:00

  • Encoding of movement dynamics by Purkinje cell simple spike activity during fast arm movements under resistive and assistive force fields.

    abstract::It is controversial whether simple-spike activity of cerebellar Purkinje cells during arm movements encodes movement kinematics like velocity or dynamics like muscle activities. To examine this issue, we trained monkeys to flex or extend the elbow by 45 degrees in 400 ms under resistive and assistive force fields but ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00206.2006

    authors: Yamamoto K,Kawato M,Kotosaka S,Kitazawa S

    更新日期:2007-02-01 00:00:00

  • Activity of commissural interneurons in spinal cord of Xenopus embryos.

    abstract::Horseradish peroxidase- (HRP) filled microelectrodes have been used to examine the anatomy and physiology of "commissural interneurons," a morphologically defined class of spinal cord interneuron in Xenopus laevis embryos. Commissural interneurons have unipolar cell bodies in the dorsal half of the spinal cord. Their ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1984.51.6.1257

    authors: Soffe SR,Clarke JD,Roberts A

    更新日期:1984-06-01 00:00:00

  • Effects of spaceflight on rhesus quadrupedal locomotion after return to 1G.

    abstract::Effects of spaceflight on Rhesus quadrupedal locomotion after return to 1G. Locomotor performance, activation patterns of the soleus (Sol), medial gastrocnemius (MG), vastus lateralis (VL), and tibialis anterior (TA) and MG tendon force during quadrupedal stepping were studied in adult Rhesus before and after 14 days ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.81.5.2451

    authors: Recktenwald MR,Hodgson JA,Roy RR,Riazanski S,McCall GE,Kozlovskaya I,Washburn DA,Fanton JW,Edgerton VR

    更新日期:1999-05-01 00:00:00

  • Relationships between neck muscle electromyography and three-dimensional head kinematics during centrally induced torsional head perturbations.

    abstract::The relationship between neck muscle electromyography (EMG) and torsional head rotation (about the nasooccipital axis) is difficult to assess during normal gaze behaviors with the head upright. Here, we induced acute head tilts similar to cervical dystonia (torticollis) in two monkeys by electrically stimulating 20 in...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00312.2012

    authors: Farshadmanesh F,Byrne P,Wang H,Corneil BD,Crawford JD

    更新日期:2012-12-01 00:00:00

  • Neuronal responses to target onset in oculomotor and somatomotor parietal circuits differ markedly in a choice task.

    abstract::We often look at and sometimes reach for visible targets. Looking at a target is fast and relatively easy. By comparison, reaching for an object is slower and is associated with a larger cost. We hypothesized that, as a result of these differences, abrupt visual onsets may drive the circuits involved in saccade planni...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00968.2012

    authors: Kubanek J,Wang C,Snyder LH

    更新日期:2013-11-01 00:00:00

  • Glycine receptors involved in synaptic transmission are selectively regulated by the cytoskeleton in mouse spinal neurons.

    abstract::Using whole cell patch-clamp recordings, we examined the effect of colchicine, a microtubule disrupter, on the properties of glycine receptors (GlyRs) in cultured spinal cord neurons. Confocal microscopy revealed that colchicine treatment effectively altered microtubule bundles and neuronal morphology. Application of ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00455.2001

    authors: van Zundert B,Alvarez FJ,Yevenes GE,Cárcamo JG,Vera JC,Aguayo LG

    更新日期:2002-01-01 00:00:00

  • Temporal resolution in olfaction II: time course of recovery from adaptation in lobster chemoreceptor cells.

    abstract::1. Adaptation and disadaptation rates determine the temporal response properties of sensory receptor cells. In chemoreception, temporal filter properties of receptor cells are poorly understood. We studied the time course of disadaptation in lobster antennular chemoreceptor cells by using in situ high-resolution stimu...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.76.2.1340

    authors: Gomez G,Atema J

    更新日期:1996-08-01 00:00:00

  • Dopamine regulates distinctively the activity patterns of striatal output neurons in advanced parkinsonian primates.

    abstract::Nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of Parkinson's disease (PD). Studies in rodent and primate models have revealed that striatal projection neurons, namely, medium spiny neurons (MSNs), increase the firing frequency. However, their activity...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00910.2014

    authors: Singh A,Liang L,Kaneoke Y,Cao X,Papa SM

    更新日期:2015-03-01 00:00:00

  • The effect of attention on neuronal responses to high and low contrast stimuli.

    abstract::It remains unclear how attention affects the tuning of individual neurons in visual cerebral cortex. Some observations suggest that attention preferentially enhances responses to low contrast stimuli, whereas others suggest that attention proportionally affects responses to all stimuli. Resolving how attention affects...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01019.2009

    authors: Lee J,Maunsell JH

    更新日期:2010-08-01 00:00:00

  • Contribution of near-threshold currents to intrinsic oscillatory activity in rat medial entorhinal cortex layer II stellate cells.

    abstract::The temporal lobe is well known for its oscillatory activity associated with exploration, navigation, and learning. Intrinsic membrane potential oscillations (MPOs) and resonance of stellate cells (SCs) in layer II of the entorhinal cortex are thought to contribute to network oscillations and thereby to the encoding o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00743.2011

    authors: Boehlen A,Henneberger C,Heinemann U,Erchova I

    更新日期:2013-01-01 00:00:00

  • Proximal arm kinematics affect grip force-load force coordination.

    abstract::During object manipulation, grip force is coordinated with load force, which is primarily determined by object kinematics. Proximal arm kinematics may affect grip force control, as proximal segment motion could affect control of distal hand muscles via biomechanical and/or neural pathways. The aim of this study was to...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00227.2015

    authors: Vermillion BC,Lum PS,Lee SW

    更新日期:2015-10-01 00:00:00

  • Slow brain potential and oscillatory EEG manifestations of impaired temporal preparation in Parkinson's disease.

    abstract::Performance in behavioral tasks is influenced by temporal expectations shaped by the temporal structure of the task. Such implicit temporal preparation is reflected in slow brain potentials and electroencephalographic oscillations and is attributed to interval timing mechanisms that probably depend on intact basal gan...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00224.2007

    authors: Praamstra P,Pope P

    更新日期:2007-11-01 00:00:00