Behavioral triggers of skin conductance responses and their neural correlates in the primate amygdala.

Abstract:

:The amygdala plays a crucial role in evaluating the emotional significance of stimuli and in transforming the results of this evaluation into appropriate autonomic responses. Lesion and stimulation studies suggest involvement of the amygdala in the generation of the skin conductance response (SCR), which is an indirect measure of autonomic activity that has been associated with both emotion and attention. It is unclear if this involvement marks an emotional reaction to an external stimulus or sympathetic arousal regardless of its origin. We recorded skin conductance in parallel with single-unit activity from the right amygdala of two rhesus monkeys during a rewarded image viewing task and while the monkeys sat alone in a dimly lit room, drifting in and out of sleep. In both experimental conditions, we found similar SCR-related modulation of activity at the single-unit and neural population level. This suggests that the amygdala contributes to the production or modulation of SCRs regardless of the source of sympathetic arousal.

journal_name

J Neurophysiol

authors

Laine CM,Spitler KM,Mosher CP,Gothard KM

doi

10.1152/jn.91110.2008

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

1749-54

issue

4

eissn

0022-3077

issn

1522-1598

pii

91110.2008

journal_volume

101

pub_type

杂志文章
  • The role of vibration in tactile speed perception.

    abstract::The relative motion between the surface of an object and our fingers produces patterns of skin deformation such as stretch, indentation, and vibrations. In this study, we hypothesized that motion-induced vibrations are combined with other tactile cues for the discrimination of tactile speed. Specifically, we hypothesi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00621.2015

    authors: Dallmann CJ,Ernst MO,Moscatelli A

    更新日期:2015-12-01 00:00:00

  • Stimulus-evoked modulation of sensorimotor pyramidal neuron EPSPs.

    abstract::Sensory cortical neurons display substantial receptive field dynamics during and after persistent sensory drive. Because a cell's response properties are determined by the inputs it receives, receptive field dynamics are likely to involve changes in the relative efficacy of different inputs to the cell. To test this h...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01012.2001

    authors: Kohn A,Metz C,Tommerdahl MA,Whitsel BL

    更新日期:2002-12-01 00:00:00

  • Fiber architecture and histochemistry in the cat neck muscle, biventer cervicis.

    abstract::1. Biventer cervicis (BC) is an anatomically complex muscle that is divided by tendinous inscriptions into five in-series compartments of motor units. We have analyzed the fiber architecture and fiber-type composition of these different compartments using microdissection and histochemical methods. 2. BC narrows as it ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.1.46

    authors: Richmond FJ,Armstrong JB

    更新日期:1988-07-01 00:00:00

  • Positive force feedback control of muscles.

    abstract::This study was prompted by recent evidence for the existence of positive force feedback in feline locomotor control. Our aim was to establish some basic properties of positive force feedback in relation to load compensation, stability, intrinsic muscle properties, and interaction with displacement feedback. In human s...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.77.6.3226

    authors: Prochazka A,Gillard D,Bennett DJ

    更新日期:1997-06-01 00:00:00

  • Characteristics of midbrain control of spinal nociceptive neurons and nonsomatosensory parameters in the pentobarbital-anesthetized rat.

    abstract::1. GABAergic mechanisms in the midbrain periaqueductal gray (PAG) have been proposed to control the activity of descending antinociceptive systems and defensive behavior. Here, the effect of neuronal disinhibition by gamma-aminobutyric acid (GABAA) receptor blockade at midbrain sites on spinal neuronal responses to no...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.1.33

    authors: Sandkühler J,Willmann E,Fu QG

    更新日期:1991-01-01 00:00:00

  • Retinotopic organization of lateral eye input to Limulus brain.

    abstract::1. The retinotopic organization of retinal inputs from the lateral eye of Limulus to the optic ganglia of the brain was determined from microelectrode recordings of nerve impulses. 2. The central connections of the natural subunits of the lateral optic nerve were determined using cobalt impregnation of cut axons. 3. C...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1982.48.2.505

    authors: Chamberlain SC,Barlow RB Jr

    更新日期:1982-08-01 00:00:00

  • Instructed delay discharge in primary and secondary somatosensory cortex within the context of a selective attention task.

    abstract::The neuronal mechanisms that contribute to tactile perception were studied using single-unit recordings from the cutaneous hand representation of primate primary (S1) and secondary (S2) somatosensory cortex. This study followed up on our recent observation that S1 and S2 neurons developed a sustained change in dischar...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.91121.2008

    authors: Meftah el-M,Bourgeon S,Chapman CE

    更新日期:2009-05-01 00:00:00

  • IA in Kenyon cells of the mushroom body of honeybees resembles shaker currents: kinetics, modulation by K+, and simulation.

    abstract::Cultured Kenyon cells from the mushroom body of the honeybee, Apis mellifera, show a voltage-gated, fast transient K+ current that is sensitive to 4-aminopyridine, an A current. The kinetic properties of this A current and its modulation by extracellular K+ ions were investigated in vitro with the whole cell patch-cla...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.81.4.1749

    authors: Pelz C,Jander J,Rosenboom H,Hammer M,Menzel R

    更新日期:1999-04-01 00:00:00

  • Metabotropic glutamate receptors in the lateral superior olive activate TRP-like channels: age- and experience-dependent regulation.

    abstract::The lateral superior olive (LSO) is the primary auditory nucleus for processing of interaural sound level differences, which is one of the major cues for sound localization. During development, survival and maturation of LSO neurons critically depend on synaptic activity and intracellular calcium signaling. Before hea...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00686.2006

    authors: Ene FA,Kalmbach A,Kandler K

    更新日期:2007-05-01 00:00:00

  • Group I metabotropic glutamate receptors are differentially expressed by two populations of olfactory bulb granule cells.

    abstract::In the main olfactory bulb, several populations of granule cells (GCs) can be distinguished based on the soma location either superficially, interspersed with mitral cells within the mitral cell layer (MCL), or deeper, within the GC layer (GCL). Little is known about the physiological properties of superficial GCs (sG...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01202.2006

    authors: Heinbockel T,Hamilton KA,Ennis M

    更新日期:2007-04-01 00:00:00

  • GAT-3 transporters regulate inhibition in the neocortex.

    abstract::The role of GAT-3 transporters in regulating GABA(A) receptor-mediated inhibition was examined in the rat neocortex using an in vitro slice preparation. Pharmacologically isolated GABA(A) receptor-mediated responses were recorded from layer V neocortical pyramidal cells, and the effects of SNAP-5114, a GAT-3 GABA tran...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00420.2005

    authors: Kinney GA

    更新日期:2005-12-01 00:00:00

  • Powerful, onset inhibition in the ventral nucleus of the lateral lemniscus.

    abstract::The function of the ventral nucleus of the lateral lemniscus (VNLL), a secondary processing site within the auditory brain stem, is unclear. It is known to be a major source of inhibition to the inferior colliculus (IC). It is also thought to play a role in coding the temporal aspects of sound, such as onsets and the ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00167.2005

    authors: Nayagam DA,Clarey JC,Paolini AG

    更新日期:2005-08-01 00:00:00

  • Preferential correlations of a medullary neuron's activity to different sympathetic outflows as revealed by partial coherence analysis.

    abstract::1. In vagotomized, paralyzed, decerebrate cats, simultaneous recordings were taken from one or more sympathetic nerves [cervical sympathetic (CS), inferior cardiac (IC), splanchnic (SP)] and from medullary neurons in vasomotor-related regions. Coherence analyses were used to ascertain the presence of sympathetic rhyth...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.74.1.474

    authors: Cohen MI,Yu Q,Huang WX

    更新日期:1995-07-01 00:00:00

  • Locomotor training improves reciprocal and nonreciprocal inhibitory control of soleus motoneurons in human spinal cord injury.

    abstract::Pathologic reorganization of spinal networks and activity-dependent plasticity are common neuronal adaptations after spinal cord injury (SCI) in humans. In this work, we examined changes of reciprocal Ia and nonreciprocal Ib inhibition after locomotor training in 16 people with chronic SCI. The soleus H-reflex depress...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00872.2014

    authors: Knikou M,Smith AC,Mummidisetty CK

    更新日期:2015-04-01 00:00:00

  • Endocannabinoid-mediated depolarization-induced suppression of inhibition in hilar mossy cells of the rat dentate gyrus.

    abstract::Hilar mossy cells represent a unique population of local circuit neurons in the hippocampus and dentate gyrus. Here we use electrophysiological techniques in acute preparations of hippocampal slices to demonstrate that depolarization of a single hilar mossy cell can produce robust inhibition of local GABAergic afferen...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00310.2006

    authors: Hofmann ME,Nahir B,Frazier CJ

    更新日期:2006-11-01 00:00:00

  • Effects of reversible spinalization on the visceral input to viscerosomatic neurons in the lower thoracic spinal cord of the cat.

    abstract::Single-unit electrical activity has been recorded from 122 viscerosomatic neurons in the T9 and T11 segments of the cat's spinal cord. These neurons were excited by electrical and/or natural stimulation of visceral and somatic afferent fibers. The majority of viscerosomatic neurons (72%) received somatic nociceptive i...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1986.56.3.785

    authors: Tattersall JE,Cervero F,Lumb BM

    更新日期:1986-09-01 00:00:00

  • Analysis of afferent responses from isolated semicircular canal of the guitarfish using rotational acceleration white-noise inputs. I. Correlation of response dynamics with receptor innervation.

    abstract::The small-signal linear characteristics of afferent responses from the isolated semicircular canal were described by the use of white-noise rotational acceleration inputs. The results, based on cross-correlation analysis, showed a striking and systematic variation in linear system impulse response characteristics from...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1976.39.3.631

    authors: O'Leary DP,Dunn RF

    更新日期:1976-05-01 00:00:00

  • Generation and coordination of heartbeat timing oscillation in the medicinal leech. II. Intersegmental coordination.

    abstract::1. A network of four pairs of interneurons, HN(1)-HN(4), times the heartbeat of the medicinal leech. The following model accounts for the stable phase relationships in the network and the network's response to perturbation, entrainment, and stimulation. 2. There are two centers of oscillation, one the HN(3) pair in th...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1983.49.3.627

    authors: Peterson EL

    更新日期:1983-03-01 00:00:00

  • Glutamate-induced long-term potentiation enhances spontaneous EPSC amplitude but not frequency.

    abstract::1. Many examples of long-term potentiation (LPT) are induced by repetitive electrical stimulation of presynaptic axons. LTP also is induced by direct glutamate iontophoresis (1 M, 1-2 microA, 10 s) onto postsynaptic neurons in hippocampal slices without evoked presynaptic stimulation; this form of LTP is called "ionto...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.75.5.1909

    authors: Cormier RJ,Kelly PT

    更新日期:1996-05-01 00:00:00

  • Investigation of the juxtamembrane region of neuronal-Synaptobrevin in synaptic transmission at the Drosophila neuromuscular junction.

    abstract::In this study, the juxtamembrane region of the Drosophila SNARE protein neuronal-Synaptobrevin (n-Syb) was tested for its role in synaptic transmission. A transgenic approach was used to express n-Syb mutant genes. The transgenes carried engineered point mutations that alter the amino acid sequence of the conserved tr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00474.2013

    authors: DeMill CM,Qiu X,Kisiel M,Bolotta A,Stewart BA

    更新日期:2014-09-15 00:00:00

  • Inhibition and facilitation of different nocifensor reflexes by spatially remote noxious stimuli.

    abstract::1. Noxious stimuli have been shown to produce a diffuse inhibition of nociresponsive neurons in the spinal and trigeminal dorsal horns. The present study sought to extend these electrophysiological studies of diffuse noxious inhibitory controls (DNIC) by determining the effect of a spatially remote noxious stimulus on...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.72.3.1152

    authors: Morgan MM,Heinricher MM,Fields HL

    更新日期:1994-09-01 00:00:00

  • Faster processing of moving compared with flashed bars in awake macaque V1 provides a neural correlate of the flash lag illusion.

    abstract::When the brain has determined the position of a moving object, because of anatomical and processing delays the object will have already moved to a new location. Given the statistical regularities present in natural motion, the brain may have acquired compensatory mechanisms to minimize the mismatch between the perceiv...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00792.2017

    authors: Subramaniyan M,Ecker AS,Patel SS,Cotton RJ,Bethge M,Pitkow X,Berens P,Tolias AS

    更新日期:2018-11-01 00:00:00

  • Synaptic transmission at parasympathetic neurons of the major pelvic ganglion from normal and diabetic male mice.

    abstract::Bladder and erectile dysfunction are common urologic complications of diabetes and are associated with reduced parasympathetic autonomic control. To determine whether disruption of ganglionic neurotransmission contributes to the loss of function, we investigated synaptic transmission at parasympathetic, major pelvic g...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00354.2012

    authors: Tompkins JD,Vizzard MA,Parsons RL

    更新日期:2013-02-01 00:00:00

  • Capacity of vertical VOR adaptation in squirrel monkey.

    abstract::Squirrel monkeys were trained using newly developed visual-vestibular mismatch paradigms to test the asymmetrical simultaneous induction of vertical vestibuloocular reflex (VOR) gain changes in opposite directions (high and low) either in the upward and downward directions or in response to high- and low-frequency sti...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00698.2001

    authors: Hirata Y,Lockard JM,Highstein SM

    更新日期:2002-12-01 00:00:00

  • Maintaining balance against force perturbations: impaired mechanisms unresponsive to levodopa in Parkinson's disease.

    abstract::There is evidence that postural instability associated with Parkinson's disease (PD) is not adequately improved by levodopa, implying involvement of nondopaminergic pathways. However, the mechanisms contributing to postural instability have yet to be fully identified and tested for their levodopa responsiveness. In th...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00996.2015

    authors: Di Giulio I,St George RJ,Kalliolia E,Peters AL,Limousin P,Day BL

    更新日期:2016-08-01 00:00:00

  • Cerebellar contributions to self-motion perception: evidence from patients with congenital cerebellar agenesis.

    abstract::The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00763.2015

    authors: Dahlem K,Valko Y,Schmahmann JD,Lewis RF

    更新日期:2016-05-01 00:00:00

  • Repetition suppression in monkey inferotemporal cortex: relation to behavioral priming.

    abstract::In tasks requiring judgments about visual stimuli, humans exhibit repetition priming, responding with increased speed when a stimulus is repeated. Repetition priming might depend on repetition suppression, a phenomenon first observed in monkey inferotemporal cortex (IT) whereby, when a stimulus is repeated, the streng...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01042.2006

    authors: McMahon DB,Olson CR

    更新日期:2007-05-01 00:00:00

  • Electrical interaction between motoneurons and afferent terminals in cat spinal cord.

    abstract::1. The electrical threshold of the terminations of single group Ia and II afferent fibers was transiently reduced by the antidromic discharge of the initial segment of spinal motoneurons in the cat. 2. This depolarization of the terminals of afferent fibers known to synapse on motoneurons confirms previous observation...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1979.42.3.635

    authors: Curtis DR,Lodge D,Headley PM

    更新日期:1979-05-01 00:00:00

  • Rapid and precise retinotopic mapping of the visual cortex obtained by voltage-sensitive dye imaging in the behaving monkey.

    abstract::Retinotopy is a fundamental organizing principle of the visual cortex. Over the years, a variety of techniques have been used to examine it. None of these techniques, however, provides a way to rapidly characterize retinotopy, at the submillimeter range, in alert, behaving subjects. Voltage-sensitive dye imaging (VSDI...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00417.2007

    authors: Yang Z,Heeger DJ,Seidemann E

    更新日期:2007-08-01 00:00:00

  • Risky business: disambiguating ambiguity-related responses in the brain.

    abstract::Previous functional MRI studies reported neural correlates of risk and ambiguity based on behavioral economic theories. A recent study controlled for uncertainty by adding noise to information of an impending aversive event and demonstrated brain areas that did not track the degree of uncertainty: the activation peake...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章,评审

    doi:10.1152/jn.00406.2009

    authors: O'Neill M,Kobayashi S

    更新日期:2009-08-01 00:00:00