Hour-long adaptation in the awake early visual system.

abstract：:1. Long-term depression (LTD) is an activity-dependent reduction in the strength of synaptic transmission that can persist for hours. It is a neural model for processes underlying learning and memory, such as extinction and forgetting. LTD of excitatory postsynaptic potentials (EPSPs) in cells of the CA1 region of hip...

journal_title：Journal of neurophysiology

authors： Christofi G,Nowicky AV,Bolsover SR,Bindman LJ

更新日期：1993-01-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:The aim of this study was to investigate how maximal intermittent contractions for a hand muscle influence cortical and reflex activity, as well as the ability to voluntarily activate, the homologous muscle in the opposite limb. Twelve healthy subjects (age: 24 ± 3 years, all right hand dominant) performed maximal con...

journal_title：Journal of neurophysiology

authors： Kavanagh JJ,Feldman MR,Simmonds MJ

更新日期：2016-11-01 00:00:00

abstract：:It is controversial whether simple-spike activity of cerebellar Purkinje cells during arm movements encodes movement kinematics like velocity or dynamics like muscle activities. To examine this issue, we trained monkeys to flex or extend the elbow by 45 degrees in 400 ms under resistive and assistive force fields but ...

journal_title：Journal of neurophysiology

authors： Yamamoto K,Kawato M,Kotosaka S,Kitazawa S

更新日期：2007-02-01 00:00:00

abstract：:To investigate the specificity of fusimotor (gamma) drive during locomotion, gamma-efferents were recorded from the flexor digitorum longus (FDL) and flexor hallucis longus (FHL) nerves in a decerebrate cat preparation. These nerves innervate hindlimb muscles that differ in some aspects of their mechanical action. For...

journal_title：Journal of neurophysiology

authors： Murphy PR

更新日期：2002-01-01 00:00:00

abstract：:1. Intrasomal recordings were made with microelectrodes from 153 warm (infrared) neurons in the trigeminal ganglia of 36 crotaline snakes, Trimeresurus flavoviridis. Background discharges were observed at room temperature. The 153 warm neurons were classified into two groups: 81 were sensitive to less than or equal to...

journal_title：Journal of neurophysiology

authors： Terashima S,Liang YF

更新日期：1991-08-01 00:00:00

abstract：:Experience-dependent modification in the electrical properties of central neurons is a form of intrinsic plasticity that occurs during development and has been observed following behavioral learning. We report a novel form of intrinsic plasticity in hippocampal CA1 pyramidal neurons mediated by the KV7/KCNQ and CaV1/L...

journal_title：Journal of neurophysiology

authors： Wu WW,Chan CS,Surmeier DJ,Disterhoft JF

更新日期：2008-10-01 00:00:00

abstract：:1. Effects of hypothalamic stimulation on activity of dorsomedial medulla neurons that responded to subdiaphragmatic vagal stimulation were investigated in urethan-anesthetized rats. 2. Extracellular recordings were made from 231 neurons in the nucleus of the tractus solitarius (NTS) that fired repetitively in respons...

journal_title：Journal of neurophysiology

authors： Nishimura H,Oomura Y

更新日期：1987-10-01 00:00:00

abstract：:Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

journal_title：Journal of neurophysiology

authors： Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

更新日期：2020-02-01 00:00:00

abstract：:Current-clamp recordings were made from the deep cerebellar nuclei (DCN) of 12- to 15-day-old rats to understand the factors that mediate intrinsic spontaneous firing patterns. All of the cells recorded were spontaneously active with spiking patterns ranging continuously from regular spiking to spontaneous bursting wi...

journal_title：Journal of neurophysiology

authors： Aizenman CD,Linden DJ

更新日期：1999-10-01 00:00:00

abstract：:Individuals with cerebral palsy (CP) experience impairments in the control of head and neck movements, suggesting dysfunction in brain stem circuitry. To examine if brain stem circuitry is altered in CP, we compared reflexes evoked in the sternocleidomastoid (SCM) muscle by trigeminal nerve stimulation in adults with ...

journal_title：Journal of neurophysiology

authors： Smith AT,Gorassini MA

更新日期：2018-09-01 00:00:00

abstract：:The functional significance of vestibular information for the generation of gaze shifts is controversial and less well established than the vestibular contribution to gaze stability. In this study, we asked seven bilaterally avestibular patients to execute voluntary, whole body pivot turns to visual targets up to 180°...

journal_title：Journal of neurophysiology

authors： Anastasopoulos D,Ziavra N,Bronstein AM

更新日期：2019-11-01 00:00:00

abstract：:People naturally direct their gaze to visible hand movement goals. Doing so improves reach accuracy through use of signals related to gaze position and visual feedback of the hand. Here, we studied where people naturally look when acting on remembered target locations. Four targets were presented on a screen, in perip...

journal_title：Journal of neurophysiology

authors： Flanagan JR,Terao Y,Johansson RS

更新日期：2008-09-01 00:00:00

abstract：:The purpose of this study was to examine changes in motor unit activity in the biceps brachii muscle after an initial (Bout 1) and repeated (Bout 2) session of eccentric exercise separated by 1 wk. Eight subjects (aged 22 ± 2 yr) participated in experimental assessments of neuromuscular function obtained before, immed...

journal_title：Journal of neurophysiology

authors： Dartnall TJ,Nordstrom MA,Semmler JG

更新日期：2011-03-01 00:00:00

abstract：:1. The discharge patterns of 359 single neurons in the hand representation of primary somatosensory cortex (SI) of two monkeys (Macaca mulatta) were recorded during the performance of a passive texture discrimination task with the contralateral hand (104 in area 3b, 149 in area 1, and 106 in area 2). Three nyloprint s...

journal_title：Journal of neurophysiology

authors： Tremblay F,Ageranioti-Bélanger SA,Chapman CE

更新日期：1996-11-01 00:00:00

abstract：:1. We have investigated the electrical properties of neurons acutely dissociated from the substantia nigra zona compacta (SNZC) of the postnatal rat with whole cell patch-clamp recordings. Retrogradely labeled nigrostriatal neurons were identified with the use of rhodamine-labeled fluorescent latex microspheres. Over ...

journal_title：Journal of neurophysiology

authors： Silva NL,Pechura CM,Barker JL

更新日期：1990-07-01 00:00:00

abstract：:Expression of the 5-HT(1Apl(a)) receptor in Aplysia pleural sensory neurons inhibited 5-HT-mediated translocation of the novel PKC Apl II in sensory neurons and prevented PKC-dependent synaptic facilitation at sensory to motoneuron synapses (Nagakura et al. 2010). We now demonstrate that the ability of inhibitory rece...

journal_title：Journal of neurophysiology

authors： Dunn TW,Farah CA,Sossin WS

更新日期：2012-01-01 00:00:00

abstract：:ACh modulates neuronal activity throughout the cerebral cortex, including the primary visual cortex (V1). However, a number of issues regarding this modulation remain unknown, such as the effect and its function and the receptor subtypes involved. To address these issues, we combined extracellular single-unit recordin...

journal_title：Journal of neurophysiology

authors： Soma S,Shimegi S,Osaki H,Sato H

更新日期：2012-01-01 00:00:00

abstract：:Animals are adapted to respond quickly to threats in their environment. In many invertebrate and some vertebrate species, the evolutionary pressures have resulted in rapidly conducting giant axons, which allow short response times. Although neural circuits mediating escape behavior are identified in several species, l...

journal_title：Journal of neurophysiology

authors： Mullins OJ,Hackett JT,Friesen WO

更新日期：2011-01-01 00:00:00

abstract：:1. The antidromic compound action potential (ACAP) of the auditory nerve was evoked by shocks to the auditory nerve root and recorded at the round window of the cochlea in anesthetized guinea pigs. The goal of this study was to determine the characteristics of the ACAP and compare these characteristics with those of t...

journal_title：Journal of neurophysiology

authors： Brown MC

更新日期：1994-05-01 00:00:00

abstract：:Recent physiological studies have suggested that there are several sites of interaction between the neural pathways that control saccadic eye movements and those that control visual pursuit movements. To address the question of saccade/pursuit interaction from a neuroanatomical point of view, we have studied the conne...

journal_title：Journal of neurophysiology

authors： Yan YJ,Cui DM,Lynch JC

更新日期：2001-12-01 00:00:00

abstract：:Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

journal_title：Journal of neurophysiology

authors： De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

更新日期：2015-03-15 00:00:00

abstract：:In humans, functional magnetic resonance imaging (fMRI) activity in the anterior cingulate cortex (ACC) and the nucleus accumbens (NAc) appears to reflect affective and motivational aspects of pain. The responses of this reward-aversion circuit to relief of pain, however, have not been investigated in detail. Moreover...

journal_title：Journal of neurophysiology

authors： Becerra L,Navratilova E,Porreca F,Borsook D

更新日期：2013-09-01 00:00:00

abstract：:Interhemispheric interactions through the corpus callosum play an important role in the control of bimanual forces. However, the extent to which physiological connections between primary motor cortices are modulated during increasing levels of bimanual force generation in intact humans remains poorly understood. Here ...

journal_title：Journal of neurophysiology

authors： Long J,Tazoe T,Soteropoulos DS,Perez MA

更新日期：2016-03-01 00:00:00

abstract：:1. Previous studies indicate that after transection of the rostral spinal cord, larval lamprey begin to recover locomotor behavior 2 wk posttransection and recovery is complete at approximately 8 wk. To examine the mechanisms underlying behavioral recovery after spinal cord transection, in the present study the time c...

journal_title：Journal of neurophysiology

authors： McClellan AD

更新日期：1994-08-01 00:00:00

abstract：:Biological gain mechanisms regulate the sensitivity and dynamics of signaling pathways at the systemic, cellular, and molecular levels. In the sympathetic nervous system, gain in sensory-motor feedback loops is essential for homeostatic regulation of blood pressure and body temperature. This study shows how synaptic c...

journal_title：Journal of neurophysiology

authors： Wheeler DW,Kullmann PH,Horn JP

更新日期：2004-11-01 00:00:00

abstract：:Reaching movements are subject to noise associated with planning and execution, but precisely how these noise sources interact to determine patterns of endpoint variability in three-dimensional space is not well understood. For frontal plane movements, variability is largest along the depth axis (the axis along which ...

journal_title：Journal of neurophysiology

authors： Apker GA,Buneo CA

更新日期：2012-01-01 00:00:00

abstract：:Mechanisms of direction selectivity and speed selectivity were studied in single neurons of the middle temporal visual area (MT) of behaving macaque monkeys. Visual stimuli were presented in both smooth and stroboscopic motion within a neuron's receptive field as the monkey fixated a stationary point of light. Directi...

journal_title：Journal of neurophysiology

authors： Mikami A,Newsome WT,Wurtz RH

更新日期：1986-06-01 00:00:00

abstract：:There are at least two respiration-related rhythm generators in the medulla: the pre-Bötzinger complex, which produces inspiratory (Insp) neuron bursts, and the parafacial respiratory group (pFRG), which produces predominantly preinspiratory (Pre-I) neuron bursts. The pFRG Pre-I neuron activity has not been correlated...

journal_title：Journal of neurophysiology

authors： Onimaru H,Kumagawa Y,Homma I

更新日期：2006-07-01 00:00:00

abstract：:The preceding study demonstrated that normal subjects compensate for the additional interaction torques generated when a reaching movement is made during voluntary trunk rotation. The present paper assesses the influence of trunk rotation on finger trajectories and on interjoint coordination and determines whether sim...

journal_title：Journal of neurophysiology

authors： Pigeon P,Bortolami SB,DiZio P,Lackner JR

更新日期：2003-01-01 00:00:00