Reciprocal modulation of calcium dynamics at rod and cone photoreceptor synapses by nitric oxide.

abstract：:N-methyl-D-aspartate receptors (NMDARs) are known to regulate axonal refinement and dendritic branching. However, because NMDARs are abundantly present as tri-heteromers (e.g., NR1/NR2A/NR2B) during development, the precise role of the individual subunits NR2A and NR2B in these processes has not been elucidated. Ventr...

journal_title：Journal of neurophysiology

authors： Sepulveda FJ,Bustos FJ,Inostroza E,Zúñiga FA,Neve RL,Montecino M,van Zundert B

更新日期：2010-04-01 00:00:00

abstract：:The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...

journal_title：Journal of neurophysiology

authors： Zayachkivsky A,Lehmkuhle MJ,Ekstrand JJ,Dudek FE

更新日期：2015-11-01 00:00:00

abstract：:The location of the human nociceptive area(s) near the Sylvian fissure is still controversial in spite of evidence from imaging and evoked potential studies that noxious heat stimuli activate somatosensory areas in that region. Some studies have suggested the secondary somatosensory cortex (SII) on the upper bank of t...

journal_title：Journal of neurophysiology

authors： Vogel H,Port JD,Lenz FA,Solaiyappan M,Krauss G,Treede RD

更新日期：2003-06-01 00:00:00

abstract：:Synchronization of local and distributed neuronal assemblies is thought to underlie fundamental brain processes such as perception, learning, and cognition. In neurological disease, neuronal synchrony can be altered and in epilepsy may play an important role in the generation of seizures. Linear cross-correlation and ...

journal_title：Journal of neurophysiology

authors： Warren CP,Hu S,Stead M,Brinkmann BH,Bower MR,Worrell GA

更新日期：2010-12-01 00:00:00

abstract：:If a laterally displacing prism is placed in front of one eye of a person or monkey with the other eye occluded, they initially will point to one side of a target that is located directly in front of them. Normally, people and monkeys adapt easily to the displaced vision and correct their aim after a few trials. If th...

journal_title：Journal of neurophysiology

authors： Baizer JS,Kralj-Hans I,Glickstein M

更新日期：1999-04-01 00:00:00

abstract：:Electrical synapses play significant roles in neural processing in invertebrate and vertebrate nervous systems. The view of electrical synapses as plain bidirectional intercellular channels represents a partial picture because rectifying electrical synapses expand the complexity in the communication capabilities of ne...

journal_title：Journal of neurophysiology

authors： Rela L,Szczupak L

更新日期：2007-02-01 00:00:00

abstract：:1. Ca(2+)-dependent K+ currents were studied in large pyramidal neurons (Betz cells) from layer V of cat sensorimotor cortex by use of an in vitro brain slice and single microelectrode voltage clamp. The Ca(2+)-dependent outward current was taken as the difference current obtained before and after blockade of Ca2+ inf...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Spain WJ,Crill WE

更新日期：1992-01-01 00:00:00

abstract：:The normal development and the capacity to calibrate gaze-stabilizing systems may depend on normal vision during infancy. At the end of 1 yr of dark rearing, cats have gaze-stabilizing deficits similar to that of the newborn human infant including decreased monocular optokinetic nystagmus (OKN) in the nasal to tempora...

journal_title：Journal of neurophysiology

authors： Tusa RJ,Mustari MJ,Burrows AF,Fuchs AF

更新日期：2001-08-01 00:00:00

abstract：:Spontaneous negative-going potentials occurring at an average frequency of 0.7 Hz were recorded from the dentate gyrus of slices prepared from the temporal hippocampus of young adult rats. These events (here termed "dentate waves") in several respects resembled the dentate spikes described for freely moving rats durin...

journal_title：Journal of neurophysiology

authors： Colgin LL,Kubota D,Brucher FA,Jia Y,Branyan E,Gall CM,Lynch G

更新日期：2004-12-01 00:00:00

abstract：:Action potential initiation and conduction along peripheral axons is a dynamic process that displays pronounced activity dependence. In patients with neuropathic pain, differences in the modulation of axonal conduction velocity by activity suggest that this property may provide insight into some of the pathomechanisms...

journal_title：Journal of neurophysiology

authors： Tigerholm J,Petersson ME,Obreja O,Lampert A,Carr R,Schmelz M,Fransén E

更新日期：2014-05-01 00:00:00

abstract：:Little is known about the substrates for the large-scale shifts in the cortical representation produced by limb amputation. Subcortical changes likely contribute to the cortical remodeling, yet there is little data regarding the extent and pattern of reorganization in thalamus after such a massive deafferentation. Mor...

journal_title：Journal of neurophysiology

authors： Florence SL,Hackett TA,Strata F

更新日期：2000-05-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:High-frequency stimulation (HFS) is used to treat a variety of neurological diseases, yet its underlying therapeutic action is not fully elucidated. Previously, we reported that HFS-induced elevation in [K(+)](e) or bath perfusion of raised K(e)(+) depressed rat entopeduncular nucleus (EP) neuronal activity via an enh...

journal_title：Journal of neurophysiology

authors： Shin DS,Carlen PL

更新日期：2008-05-01 00:00:00

abstract：:Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used as a measure of neuronal activity, despite an incomplete understanding of the hemodynamic and neural bases for BOLD signals. Recent work by Lee and colleagues investigated whether activating genetically specified neuro...

journal_title：Journal of neurophysiology

authors： Palmer HS

更新日期：2010-10-01 00:00:00

abstract：:The development of synaptic interconnections between the cerebellum and inferior olive, the sole source of climbing fibers, could contribute to the ontogeny of certain forms of motor learning (e.g., eyeblink conditioning). Purkinje cell complex spikes are produced exclusively by climbing fibers and exhibit short- and ...

journal_title：Journal of neurophysiology

authors： Nicholson DA,Freeman JH Jr

更新日期：2003-10-01 00:00:00

abstract：:The way in which input noise perturbs the behavior of a system depends on the internal processing structure of the system. In visual psychophysics, there is a long tradition of using external noise methods (i.e., adding noise to visual stimuli) as tools for system identification. Here, we demonstrate that external noi...

journal_title：Journal of neurophysiology

authors： Tjan BS,Lestou V,Kourtzi Z

更新日期：2006-09-01 00:00:00

abstract：:According to Alexander's law (AL), the slow phase velocity of nystagmus of vestibular origin is dependent on horizontal position, with lower velocity when gaze is directed in the slow compared with the fast phase direction. Adaptive changes in the velocity-to-position neural integrator are thought to cause AL. Althoug...

journal_title：Journal of neurophysiology

authors： Bockisch CJ,Hegemann S

更新日期：2008-12-01 00:00:00

abstract：:Although studies of the principal tongue protrudor muscle genioglossus (GG) suggest that whole muscle GG electromyographic (EMG) activities are preserved in nonrapid eye movement (NREM) sleep, it is unclear what influence sleep exerts on individual GG motor unit (MU) activities. We characterized the firing patterns of...

journal_title：Journal of neurophysiology

authors： Bailey EF,Fridel KW,Rice AD

更新日期：2007-12-01 00:00:00

abstract：:In this paper, the predictive capability of surface and untargeted intramuscular electromyography (EMG) was compared with respect to wrist-joint torque to quantify which type of measurement better represents joint torque during multiple degrees-of-freedom (DoF) movements for possible application in prosthetic control....

journal_title：Journal of neurophysiology

authors： Kamavuako EN,Scheme EJ,Englehart KB

更新日期：2013-06-01 00:00:00

abstract：:Membrane retrieval following exocytosis in synaptic terminals is fast and compensatory, however, little is known about the factors that regulate or contribute to this special form of endocytosis. We used whole-terminal capacitance measurements to examine the effect of hydrostatic pressure on compensatory endocytosis i...

journal_title：Journal of neurophysiology

authors： Heidelberger R,Zhou ZY,Matthews G

更新日期：2002-11-01 00:00:00

abstract：:Optogenetic activation of axons is a powerful approach for determining the synaptic properties and impact of long-range projections both in vivo and in vitro. However, because of the difficulty of measuring activity in axons, our knowledge of the reliability of optogenetic axonal stimulation has relied on data from so...

journal_title：Journal of neurophysiology

authors： Hass CA,Glickfeld LL

更新日期：2016-11-01 00:00:00

abstract：:We studied adjustments in digit forces and moments during holding a vertically oriented handle under slow, externally imposed changes in the width of the grasp. Subjects (n = 8) grasped a customized motorized handle with five digits and held it statically in the air. The handle width either increased (expanded) or dec...

journal_title：Journal of neurophysiology

authors： Zatsiorsky VM,Gao F,Latash ML

更新日期：2006-04-01 00:00:00

abstract：:While it has been well established that optostatic and optokinetic cues contribute to the perception of vertical, it is unclear how the brain processes their combined presence with the nonvisual vestibular cues. Using a psychometric approach, we examined the percept of vertical in human participants (n = 17) with thei...

journal_title：Journal of neurophysiology

authors： Niehof N,Perdreau F,Koppen M,Medendorp WP

更新日期：2019-08-01 00:00:00

abstract：:Neurons in many cortical areas involved in visuospatial processing represent remembered spatial information in retinotopic coordinates. During a gaze shift, the retinotopic representation of a target location that is fixed in the world (world-fixed reference frame) must be updated, whereas the representation of a targ...

journal_title：Journal of neurophysiology

authors： White RL 3rd,Snyder LH

更新日期：2004-04-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:Outward K+ currents were recorded using a whole cell patch-clamp configuration, from acutely dissociated adult rat cutaneous afferent dorsal root ganglion (DRG) neurons (L4 and L5) identified by retrograde labeling with Fluoro-gold. Recordings were obtained 16-24 h after dissociation from cells between 39 and 49 mm in...

journal_title：Journal of neurophysiology

authors： Everill B,Rizzo MA,Kocsis JD

更新日期：1998-04-01 00:00:00

abstract：:The ventrolateral preoptic nucleus (VLPO) is a key nucleus involved in the homeostatic regulation of sleep-wakefulness. Little is known, however, about the cellular mechanisms underlying its role in sleep regulation and how the neurotransmitters, such as GABA and noradrenaline (NA), are involved. In the present study ...

journal_title：Journal of neurophysiology

authors： Matsuo S,Jang IS,Nabekura J,Akaike N

更新日期：2003-03-01 00:00:00

abstract：:The discovery that neuroligin is a key protein involved in synapse formation offers the unprecedented opportunity to induce functional synapses between neurons and heterologous cells. We took this opportunity recording for the first-time synaptic currents in human embryonic kidney 293 (HEK293) cells transfected with n...

journal_title：Journal of neurophysiology

authors： Fu Z,Washbourne P,Ortinski P,Vicini S

更新日期：2003-12-01 00:00:00

abstract：:Current and voltage-clamp recordings were made at room temperature from cultured mouse spinal neurons using conventional two-electrode voltage-clamp techniques and electrodes filled with either 3 M KCl, 3 M CsCl, or 3 M Cs2SO4. In the presence of tetraethylammonium and tetrodotoxin, "fast" (rapidly rising and falling)...

journal_title：Journal of neurophysiology

authors： Owen DG,Segal M,Barker JL

更新日期：1986-06-01 00:00:00

abstract：:Discrete anatomic structures in the monkey somatic sensory thalamus may segregate input arising from different peripheral receptors and from different parts of the body. It has been proposed that these structures serve as components of modality- and place-specific pathways from the periphery to the cortex. We now test...

journal_title：Journal of neurophysiology

authors： Patel S,Ohara S,Dougherty PM,Gracely RH,Lenz FA

更新日期：2006-02-01 00:00:00