Responsiveness to D-glucose in neurosecretory cells of crustaceans.

Abstract:

:1. An electrophysiological study of the D-glucose sensitivity of X-organ (XO) neurosecretory cell bodies in crayfish was carried out with the use of microelectrodes, perforated, and cell-attached patch-clamp techniques. 2. Glucose depolarizes the membrane potential of XO cells in a concentration-dependent manner. 3. Depolarization produced by glucose initiates a change in the pattern of electrical activity. Silent cells began to discharge action potentials. When bursting cells are depolarized by glucose, their action potentials are no longer grouped in bursts or disappear entirely. 4. Although the membrane potential returns to its initial value after removing glucose from the bath, discharge patterns of the cells may remain different. This suggests that besides the depolarizing effect, once the cells have been exposed to glucose, the sugar switches on a process that is maintained for a long time. 5. Glucose produced a reduction of membrane steady-state conductance, and a shift of reversal potential of membrane currents to a more positive value. 6. Depolarization induced by D-glucose appears to be related with a closure of potassium channels. 7. Glucose effect was thought to be generated by a product of metabolism that would act as intracellular mediator.

journal_name

J Neurophysiol

authors

García E,Benítez A,Onetti CG

doi

10.1152/jn.1993.70.2.758

subject

Has Abstract

pub_date

1993-08-01 00:00:00

pages

758-64

issue

2

eissn

0022-3077

issn

1522-1598

journal_volume

70

pub_type

杂志文章
  • Reversible inactivation of monkey superior colliculus. I. Curvature of saccadic trajectory.

    abstract::The neurons in the intermediate layers of the monkey superior colliculus (SC) that discharge before saccadic eye movements can be divided into at least two types, burst and buildup neurons, and the differences in their characteristics are compatible with different functional contributions of the two cell types. It has...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.79.4.2082

    authors: Aizawa H,Wurtz RH

    更新日期:1998-04-01 00:00:00

  • Visual feedback during pedaling allows individuals poststroke to alter inappropriately prolonged paretic vastus medialis activity.

    abstract::Individuals who have experienced a stroke often demonstrate inappropriate muscle activity phasing in the paretic leg during locomotion. Past research has demonstrated that inappropriate paretic phasing varies between behavioral contexts and is reduced during unilateral pedaling with the nonparetic leg inactive. We inv...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00256.2017

    authors: Mullens CH,Brown DA

    更新日期:2018-06-01 00:00:00

  • Spatial phase and the temporal structure of the response to gratings in V1.

    abstract::We recorded single-unit activity of 25 units in the parafoveal representation of macaque V1 to transient appearance of sinusoidal gratings. Gratings were systematically varied in spatial phase and in one or two of the following: contrast, spatial frequency, and orientation. Individual responses were compared based on ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.80.2.554

    authors: Victor JD,Purpura KP

    更新日期:1998-08-01 00:00:00

  • Jaw muscle afferent firing during an isotonic jaw-positioning task in the monkey.

    abstract::The activity of jaw muscle receptors was studied by recording neurons in the mesencephalic nucleus of the trigeminal nerve in monkeys trained to control the position and movement of their mandible. Jaw position was measured by a weighted lever resting on the mandibular incisors. The force required to maintain the posi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1983.50.1.61

    authors: Larson CR,Finocchio DV,Smith A,Luschei ES

    更新日期:1983-07-01 00:00:00

  • Branching points of primary afferent fibers are vital for the modulation of fiber excitability by epidural DC polarization and by GABA in the rat spinal cord.

    abstract::The aim of the study was to examine whether the sustained increases in the excitability of afferent fibers traversing the dorsal columns evoked by their polarization depend on the branching points of these fibers. To this end, the effects of epidural polarization were compared in four spinal regions in deeply anesthet...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00161.2020

    authors: Li Y,Hari K,Lucas-Osma AM,Fenrich KK,Bennett DJ,Hammar I,Jankowska E

    更新日期:2020-07-01 00:00:00

  • Anticipatory postural adjustments and spatial organization of motor cortex: evidence of adaptive compensations in healthy older adults.

    abstract::During anticipated postural perturbations induced by limb movement, the central nervous system generates anticipatory postural adjustments (APAs) in the trunk and hip musculature to minimize disturbances to equilibrium. Age-related changes in functional organization of the nervous system may contribute to changes in A...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00428.2018

    authors: Smith JA,Fisher BE

    更新日期:2018-12-01 00:00:00

  • Ocular responses to translation and their dependence on viewing distance. I. Motion of the observer.

    abstract::1. The horizontal eye movements induced by acceleration along the interaural axis were recorded from five monkeys (Macaca mulatta) by the use of the electromagnetic search-coil technique. Animals sat on a sled that was moved briefly in darkness along a linear track (bell-shaped acceleration profile: peak, 400 mm/s2; d...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.66.3.851

    authors: Schwarz U,Miles FA

    更新日期:1991-09-01 00:00:00

  • Dynamic mechanisms of visually guided 3D motion tracking.

    abstract::The continuous perception of motion-through-depth is critical for both navigation and interacting with objects in a dynamic three-dimensional (3D) world. Here we used 3D tracking to simultaneously assess the perception of motion in all directions, facilitating comparisons of responses to motion-through-depth to fronto...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00831.2016

    authors: Bonnen K,Huk AC,Cormack LK

    更新日期:2017-09-01 00:00:00

  • Motor-unit synchronization is not responsible for larger motor-unit forces in old adults.

    abstract::Motor-unit synchronization, which is a measure of the near simultaneous discharge of action potentials by motor units, has the potential to influence spike-triggered average force and the steadiness of a low-force isometric contraction. The purpose of the study was to estimate the contribution of motor-unit synchroniz...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2000.84.1.358

    authors: Semmler JG,Steege JW,Kornatz KW,Enoka RM

    更新日期:2000-07-01 00:00:00

  • Human brain cortical correlates of short-latency afferent inhibition: a combined EEG-TMS study.

    abstract::When linking in time electrical stimulation of the peripheral nerve with transcranial magnetic stimulation (TMS), the excitability of the motor cortex can be modulated to evoke clear inhibition, as reflected by the amplitude decrement in the motor-evoked potentials (MEPs). This specific property, designated short-late...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00796.2011

    authors: Ferreri F,Ponzo D,Hukkanen T,Mervaala E,Könönen M,Pasqualetti P,Vecchio F,Rossini PM,Määttä S

    更新日期:2012-07-01 00:00:00

  • Hypothalamus-brain stem circuitry responsible for vagal efferent signaling to the pancreas evoked by hypoglycemia in rat.

    abstract::Circulating glucose levels significantly affect vagal neural activity, which is important in the regulation of pancreatic functions. Little is known about the mechanisms involved. This study investigates the neural pathways responsible for hypoglycemia-induced vagal efferent signaling to the pancreas and identifies th...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00791.2003

    authors: Wu X,Gao J,Yan J,Owyang C,Li Y

    更新日期:2004-04-01 00:00:00

  • Microcircuits of excitatory and inhibitory neurons in layer 2/3 of mouse barrel cortex.

    abstract::Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00917.2011

    authors: Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

    更新日期:2012-06-01 00:00:00

  • Spatiotemporal effects of microstimulation in rat neocortex: a parametric study using multielectrode recordings.

    abstract::Using microstimulation to imprint meaningful activity patterns into intrinsically highly interconnected neuronal substrates is hampered by activation of fibers of passage leading to a spatiotemporal "blur" of activity. The focus of the present study was to characterize the shape of this blur in the neocortex to arrive...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00245.2003

    authors: Butovas S,Schwarz C

    更新日期:2003-11-01 00:00:00

  • Equalization and decorrelation in primary visual cortex.

    abstract::There are many theories on the purpose of neural adaptation, but evidence remains elusive. Here, we discuss the recent work by Benucci et al. (Nat Neurosci 16: 724-729, 2013), who measured for the first time the immediate effects of adaptation on the overall activity of a neuronal population. These measurements confir...

    journal_title:Journal of neurophysiology

    pub_type: 评论,杂志文章

    doi:10.1152/jn.00521.2013

    authors: Haak KV,Fast E,Baek Y,Mesik J

    更新日期:2014-08-01 00:00:00

  • Retinotopic organization of lateral eye input to Limulus brain.

    abstract::1. The retinotopic organization of retinal inputs from the lateral eye of Limulus to the optic ganglia of the brain was determined from microelectrode recordings of nerve impulses. 2. The central connections of the natural subunits of the lateral optic nerve were determined using cobalt impregnation of cut axons. 3. C...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1982.48.2.505

    authors: Chamberlain SC,Barlow RB Jr

    更新日期:1982-08-01 00:00:00

  • Endocannabinoid-dependent neocortical layer-5 LTD in the absence of postsynaptic spiking.

    abstract::Long-term depression (LTD) was induced in neocortical layer 5 pyramidal connections by pairing presynaptic firing with subthreshold postsynaptic depolarization (dLTD) or via a spike-timing protocol (tLTD). Like tLTD, dLTD reduced short-term depression and increased the coefficient of variation consistent with a presyn...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00376.2004

    authors: Sjöström PJ,Turrigiano GG,Nelson SB

    更新日期:2004-12-01 00:00:00

  • Repetitive firing properties of neurons in the ventral region of nucleus tractus solitarius. In vitro studies in adult and neonatal rat.

    abstract::1. A brain stem slice preparation and intracellular techniques were used to examine the cellular properties of neurons within the ventral and ventrolateral region of the nucleus tractus solitarius (v-NTS) in adult and neonatal (3-12 days old) rats. These neurons are believed to be involved in the control of respirator...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.6.1213

    authors: Haddad GG,Getting PA

    更新日期:1989-12-01 00:00:00

  • Intracortical circuits in rat anterior cingulate cortex are activated by nociceptive inputs mediated by medial thalamus.

    abstract::We investigated the afferents and intracortical synaptic organization of the anterior cingulate cortex (ACC) during noxious electrical stimulation. Extracellular field potentials were recorded simultaneously from 16 electrodes spanning all layers of the ACC in male Sprague-Dawley rats anesthetized by halothane inhalat...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00623.2006

    authors: Yang JW,Shih HC,Shyu BC

    更新日期:2006-12-01 00:00:00

  • Searching for object pointers in the visual cortex.

    abstract::We perceive objects as permanent and stable despite frequent occlusions and eye movements, but their representation in the visual cortex is neither permanent nor stable. Feature selective cells respond only as long as objects are visible, and their responses depend on eye position. We explored the hypothesis that the ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00112.2020

    authors: Zhu SD,Zhang LA,von der Heydt R

    更新日期:2020-05-01 00:00:00

  • Recruitment order of cat abducens motoneurons and internuclear neurons.

    abstract::Abducens neurons undergo a dose-dependent synaptic blockade (either disinhibition or complete blockade) when tetanus neurotoxin (TeNT) is injected into the lateral rectus muscle at either a low (0.5) or a high dose (5 ng/kg). We studied the firing pattern and recruitment order in abducens neurons both in control and a...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00402.2003

    authors: Pastor AM,Gonzalez-Forero D

    更新日期:2003-10-01 00:00:00

  • Aftereffects in the responses of cat muscle spindles.

    abstract::Responses have been recorded from primary endings of muscle spindles in the cat soleus muscle. Changes in spindle responsiveness were measured following a period of conditioning that consisted of a series of rapid stretches or of tetanic ventral root stimulation. In the testing procedure the response of a single spind...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1986.56.2.451

    authors: Gregory JE,Morgan DL,Proske U

    更新日期:1986-08-01 00:00:00

  • Swimming movements elicited by electrical stimulation of turtle spinal cord. I. Low-spinal and intact preparations.

    abstract::1. Electrical stimulation applied within the dorsolateral funiculus of the spinal cord of an intact, unanesthetized turtle can elicit rhythmic limb movements similar to those observed during swimming. 2. A spontaneous display of hindlimb swimming movements is not observed in adult turtles whose spinal cord is transect...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1977.40.4.768

    authors: Lennard PR,Stein PS

    更新日期:1977-07-01 00:00:00

  • A theoretical framework for quantal analysis and its application to long-term potentiation.

    abstract::1. We present a new mathematical description of the complete distribution of electrical responses to stochastic synaptic activity (quantal analysis) that is intended as a model of experiments on central neuronal synapses. Unlike previous treatments, this distribution is calculated for each instant after the release of...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.72.3.1395

    authors: Blum KI,Idiart MA

    更新日期:1994-09-01 00:00:00

  • Generalizing movement patterns following shoulder fixation.

    abstract::Generalizing newly learned movement patterns beyond the training context is challenging for most motor learning situations. Here we tested whether learning of a new physical property of the arm during self-initiated reaching generalizes to new arm configurations. Human participants performed a single-joint elbow reach...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00696.2019

    authors: Maeda RS,Zdybal JM,Gribble PL,Pruszynski JA

    更新日期:2020-03-01 00:00:00

  • Persistent sodium currents in mesencephalic v neurons participate in burst generation and control of membrane excitability.

    abstract::The functional and biophysical properties of a persistent sodium current (I(NaP)) previously proposed to participate in the generation of subthreshold oscillations and burst discharge in mesencephalic trigeminal sensory neurons (Mes V) were investigated in brain stem slices (rats, p7-p12) using whole cell patch-clamp ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00636.2004

    authors: Wu N,Enomoto A,Tanaka S,Hsiao CF,Nykamp DQ,Izhikevich E,Chandler SH

    更新日期:2005-05-01 00:00:00

  • Activation kinetics of the delayed rectifier potassium current of bullfrog sympathetic neurons.

    abstract::We examined the activation kinetics of the delayed rectifier K+ current of bullfrog sympathetic neurons, primarily using whole cell recording. On depolarization, currents activated with a sigmoid delay but did not show a Cole-Moore shift. The time course of activation differed systematically from an exponential raised...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.79.5.2345

    authors: Klemic KG,Durand DM,Jones SW

    更新日期:1998-05-01 00:00:00

  • Sensory processing in a thermal afferent pathway.

    abstract::Extracellular recordings were made from cold-receptive afferent fibers in the trigeminal ganglion of rats anesthetized with halothane. By applying a standardized series of steady or changing temperatures to the receptive fields, we recorded the static and dynamic responses of the afferents. Comparable recordings were ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1985.53.2.429

    authors: Davies SN,Goldsmith GE,Hellon RF,Mitchell D

    更新日期:1985-02-01 00:00:00

  • Glycine response in acutely dissociated ventromedial hypothalamic neuron of the rat: new approach with gramicidin perforated patch-clamp technique.

    abstract::1. We investigated the glycine-induced response in ventromedial hypothalamic (VMH) neurons freshly dissociated from 8- to 12-day-old rats using the nystatin and gramicidin perforated patch recording modes. The nystatin-formed pores in the plasma membrane are permeable for both monovalent cations and anions, whereas th...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.72.4.1530

    authors: Abe Y,Furukawa K,Itoyama Y,Akaike N

    更新日期:1994-10-01 00:00:00

  • Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators.

    abstract::Epiretinal implants for the blind are designed to stimulate surviving retinal neurons, thus bypassing the diseased photoreceptor layer. Single-unit or multielectrode recordings from isolated animal retina are commonly used to inform the design of these implants. However, such electrical recordings provide limited info...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00852.2012

    authors: Weitz AC,Behrend MR,Lee NS,Klein RL,Chiodo VA,Hauswirth WW,Humayun MS,Weiland JD,Chow RH

    更新日期:2013-04-01 00:00:00

  • Local circuit properties underlying cortical reorganization.

    abstract::Peripheral denervation has been shown to cause reorganization of the deafferented somatotopic region in primary somatosensory cortex (S1). However, the basic mechanisms that underlie reorganization are not well understood. In the experiments described in this paper, a novel in vivo/in vitro preparation of adult rat S1...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00994.2001

    authors: Hickmott PW,Merzenich MM

    更新日期:2002-09-01 00:00:00