Structural modularity and grid activity in the medial entorhinal cortex.

abstract：:1. Intracellular recordings were made from neurons of the basolateral amygdala (BLA) in in vitro slice preparations to determine long-term differences in metabotropic glutamate receptor (mGluR) agonist-induced membrane responses in control and amygdala-kindled rats. 2. (2S,3S,4S)-alpha-(carboxycyclopropyl)glycine-1 (L...

journal_title：Journal of neurophysiology

authors： Holmes KH,Keele NB,Shinnick-Gallagher P

更新日期：1996-10-01 00:00:00

abstract：:We propose that the descending command from area 4 that is responsible, in part, for the change in limb trajectory required to step over an obstacle in one's path also plays a role in triggering the anticipatory postural modifications that accompany this movement. To test this hypothesis, we recorded the discharge cha...

journal_title：Journal of neurophysiology

authors： Kably B,Drew T

更新日期：1998-07-01 00:00:00

abstract：:Despite the peripheral and central immaturities that limit auditory processing in juvenile animals, they are able to lateralize sounds using binaural cues. This study explores a central mechanism that may compensate for these limitations during development. Interaural time and level difference processing by neurons in...

journal_title：Journal of neurophysiology

authors： Green JS,Sanes DH

更新日期：2005-12-01 00:00:00

abstract：:Activity-dependent developmental maturation of the neocortical network is thought to involve the stabilization and potentiation of immature synapses. In particular, N-methyl-d-aspartate (NMDA) receptor-dependent long-term plasticity that is expressed presynaptically appears to be crucial for the selection of functiona...

journal_title：Journal of neurophysiology

authors： Walz C,Jüngling K,Lessmann V,Gottmann K

更新日期：2006-12-01 00:00:00

abstract：:Motor-unit synchronization, which is a measure of the near simultaneous discharge of action potentials by motor units, has the potential to influence spike-triggered average force and the steadiness of a low-force isometric contraction. The purpose of the study was to estimate the contribution of motor-unit synchroniz...

journal_title：Journal of neurophysiology

authors： Semmler JG,Steege JW,Kornatz KW,Enoka RM

更新日期：2000-07-01 00:00:00

abstract：:Cacna1a encodes the pore-forming α1A subunit of CaV2.1 voltage-dependent calcium channels, which regulate neuronal excitability and synaptic transmission. Purkinje cells in the cortex of cerebellum abundantly express these CaV2.1 channels. Here, we show that homozygous tottering (tg) mice, which carry a loss-of-functi...

journal_title：Journal of neurophysiology

authors： de Oude NL,Hoebeek FE,Ten Brinke MM,de Zeeuw CI,Boele HJ

更新日期：2020-12-16 00:00:00

abstract：:Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...

journal_title：Journal of neurophysiology

authors： Estacion M,Vohra BP,Liu S,Hoeijmakers J,Faber CG,Merkies IS,Lauria G,Black JA,Waxman SG

更新日期：2015-09-01 00:00:00

abstract：:The nucleus tractus solitarii (nTS) is the initial central termination site for visceral afferents and is important for modulation and integration of multiple reflexes including cardiorespiratory reflexes. Glutamate is the primary excitatory neurotransmitter in the nTS and is removed from the extracellular milieu by e...

journal_title：Journal of neurophysiology

authors： Matott MP,Ruyle BC,Hasser EM,Kline DD

更新日期：2016-03-01 00:00:00

abstract：:1. Extracellular bath application of the selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor KN-62 to hippocampal slices in vitro blocked the induction of long-term depression (LTD) by low-frequency Schaffer collateral stimulation (1 Hz/15 min) of the same concentration as has been shown previously to pre...

journal_title：Journal of neurophysiology

authors： Stanton PK,Gage AT

更新日期：1996-09-01 00:00:00

abstract：:Stroke survivors' difficulty in releasing grasped objects may be attributable not only to impaired finger extension but also to delays in terminating activity in the gripping flexor muscles. This study was undertaken 1) to quantify the time needed to initiate and terminate grip muscular activity following stroke and 2...

journal_title：Journal of neurophysiology

authors： Seo NJ,Rymer WZ,Kamper DG

更新日期：2009-06-01 00:00:00

abstract：:Attention is thought to improve most aspects of perception. However, we recently showed that, somewhat surprisingly, endogenous attention can also lead to low subjective perceptual ratings (Rahnev et al., 2011). Here we investigated the neural basis of this effect and tested whether spontaneous fluctuations of the att...

journal_title：Journal of neurophysiology

authors： Rahnev DA,Bahdo L,de Lange FP,Lau H

更新日期：2012-09-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00

abstract：:In neuroendocrine cells, hormone release often requires a collective burst of action potentials synchronized by gap junctions. This is the case for the electrically coupled bag cell neurons in the reproductive system of the marine snail, Aplysia californica. These neuroendocrine cells are found in two clusters, and fi...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Colmers PL,Hodgson HM,Magoski NS

更新日期：2014-12-01 00:00:00

abstract：:We simultaneously compared the sensitivity of single primary afferent neurons supplying the glabrous skin of the hand and the psychophysical amplitude discrimination thresholds in human subjects for a set of vibrotactile stimuli delivered to the receptive field. All recorded afferents had a dynamic range narrower than...

journal_title：Journal of neurophysiology

authors： Arabzadeh E,Clifford CW,Harris JA,Mahns DA,Macefield VG,Birznieks I

更新日期：2014-11-15 00:00:00

abstract：:The preceding study demonstrated that normal subjects compensate for the additional interaction torques generated when a reaching movement is made during voluntary trunk rotation. The present paper assesses the influence of trunk rotation on finger trajectories and on interjoint coordination and determines whether sim...

journal_title：Journal of neurophysiology

authors： Pigeon P,Bortolami SB,DiZio P,Lackner JR

更新日期：2003-01-01 00:00:00

abstract：:1. High-voltage-activated Ca2+ currents [ICa(HVA)] were studied in immunolabeled mouse retinal ganglion neurons (RGNs) to elucidate channel-specific components and their developmental changes in vitro. 2. Neurons were dissociated at postnatal day 5. RGNs were selected for electrophysiological measurements by vital lab...

journal_title：Journal of neurophysiology

authors： Rothe T,Grantyn R

更新日期：1994-11-01 00:00:00

abstract：:Direct electrical coupling between neurons can be the result of both electrotonic current transfer through gap junctions and extracellular fields. Intracellular recordings from CA1 pyramidal neurons of rat hippocampal slices showed two different types of small-amplitude coupling potentials: short-duration (5 ms) bipha...

journal_title：Journal of neurophysiology

authors： Vigmond EJ,Perez Velazquez JL,Valiante TA,Bardakjian BL,Carlen PL

更新日期：1997-12-01 00:00:00

abstract：:The musculoskeletal redundancy of the body provides multiple solutions for performing motor tasks. We have proposed that the nervous system solves this unconstrained problem through the recruitment of motor modules or functional muscle synergies that map motor intention to action. Consistent with this hypothesis, we s...

journal_title：Journal of neurophysiology

authors： Torres-Oviedo G,Ting LH

更新日期：2010-06-01 00:00:00

abstract：:1. Serotonergic modulation of a hyperpolarization-activated inward current, Ih, and a calcium-dependent outward current, Io(Ca), was examined in the dorsal gastric (DG) motor neuron, with the use of intracellular recording techniques in an isolated preparation of the crab stomatogastric ganglion (STG). 2. Hyperpolariz...

journal_title：Journal of neurophysiology

authors： Kiehn O,Harris-Warrick RM

更新日期：1992-08-01 00:00:00

abstract：:1. The response properties of accessory optic system (AOS) neurons were assessed using single-unit extracellular recording from each of the three AOS terminal nuclei [medial, lateral, and dorsal terminal nuclei (MTN, LTN, and DTN)] in the anesthetized rabbit. 2. AOS neurons had large, monocular (contralateral) recepti...

journal_title：Journal of neurophysiology

authors： Soodak RE,Simpson JI

更新日期：1988-12-01 00:00:00

abstract：:In one series of experiments, vestibular neurons that could be activated antidromically by stimulation of the contralateral medial reticular formation were studied with extracellular recording in cats under pentobarbital anesthesia. These neurons were found in all of the four main vestibular nuclei, but were less prev...

journal_title：Journal of neurophysiology

authors： Peterson BW,Abzug C

更新日期：1975-11-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:Whereas the activation of Gαi/o-coupled receptors commonly results in postsynaptic responses that show acute desensitization, the presynaptic inhibition of transmitter release caused by many Gαi/o-coupled receptors is maintained during agonist exposure. However, an exception has been noted where GABAB receptor (GABABR...

journal_title：Journal of neurophysiology

authors： Pennock RL,Hentges ST

更新日期：2016-06-01 00:00:00

abstract：:The inferior olive is the sole source of the climbing fiber system, one of the two major afferent systems of the cerebellum; however, its exact role remains unknown. A longstanding hypothesis is that the inferior olive with its unique intrinsic rhythmic firing properties mediates motor timing. However, direct evidence...

journal_title：Journal of neurophysiology

authors： Liu T,Xu D,Ashe J,Bushara K

更新日期：2008-09-01 00:00:00

abstract：:Similar motor regions are activated during voluntarily executed or observed movements. We investigated whether observing movements of one's own hand through a mirror will generate activations in the cortical motor regions of both the moving and nonmoving hands. Using the lateralized readiness potential (LRP), an elect...

journal_title：Journal of neurophysiology

authors： Touzalin-Chretien P,Dufour A

更新日期：2008-07-01 00:00:00

abstract：:The aim of this study is to assess brain activity measured during continuous performance of design tracing tasks. Three issues were addressed: identification of brain areas involved in performing maze and square tracing tasks, investigation of differences and similarities in these areas related to dominant and nondomi...

journal_title：Journal of neurophysiology

authors： van Mier H,Tempel LW,Perlmutter JS,Raichle ME,Petersen SE

更新日期：1998-10-01 00:00:00

abstract：:Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

journal_title：Journal of neurophysiology

authors： Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

更新日期：2012-05-01 00:00:00

abstract：:The whisker region in the rodent primary motor (MI) cortex receives dense projections from neurons aligned with the layer IV septa in the whisker region of the primary somatosensory (SI) cortex. To compare whisker-induced responses in MI with respect to the SI responses in the septa and adjoining barrel regions, we us...

journal_title：Journal of neurophysiology

authors： Chakrabarti S,Zhang M,Alloway KD

更新日期：2008-07-01 00:00:00

abstract：:Express saccades represent the fastest possible eye movements to visual targets with reaction times that approach minimum sensory-motor conduction delays. Previous work in monkeys has identified two specific neural signals in the superior colliculus (SC: a midbrain sensorimotor integration structure involved in gaze c...

journal_title：Journal of neurophysiology

authors： Marino RA,Levy R,Munoz DP

更新日期：2015-08-01 00:00:00

abstract：:Complex patterns of intercellular calcium signaling occur in the CA1 and CA2 regions of hippocampal slice organotypic cultures from neonatal mice. Spontaneous localized intercellular Ca2+ waves involving 5-15 cells propagate concentrically from multiple foci in the stratum oriens and s. radiatum. In these same regions...

journal_title：Journal of neurophysiology

authors： Harris-White ME,Zanotti SA,Frautschy SA,Charles AC

更新日期：1998-02-01 00:00:00