Single tactile afferents outperform human subjects in a vibrotactile intensity discrimination task.

abstract：:1. We studied the blocking properties of a spider (Nephila clavata) toxin (JSTX) purified from venom on the spiny lobster neuromuscular junction. 2. When a small amount of JSTX was applied to the neuromuscular junction, the excitatory postsynaptic potential (EPSP) was partially suppressed. The amplitude of EPSPs remai...

journal_title：Journal of neurophysiology

authors： Miwa A,Kawai N,Saito M,Pan-Hou H,Yoshioka M

更新日期：1987-08-01 00:00:00

abstract：:This study investigated the organization of the dorsal lateral geniculate nucleus (LGN) of the tree shrew (Tupaia glis) using both microelectrode recording and anatomical techniques. The tree shrew LGN contains approximately 100,000 cells, of which 20% are in layers 2 and 6. These two layers receive input from the ips...

journal_title：Journal of neurophysiology

authors： Conway JL,Schiller PH

更新日期：1983-12-01 00:00:00

abstract：:Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

journal_title：Journal of neurophysiology

authors： Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

更新日期：2020-02-01 00:00:00

abstract：:Action observation activates brain regions involved in sensory-motor control. Recent research has shown that action observation can also facilitate motor learning; observing a tutor undergoing motor learning results in functional plasticity within the motor system and gains in subsequent motor performance. However, th...

journal_title：Journal of neurophysiology

authors： McGregor HR,Cashaback JGA,Gribble PL

更新日期：2018-12-01 00:00:00

abstract：:The scratch reflex is a motor task exhibited by the hindlimb of a turtle after complete transection of the spinal cord just posterior to the forelimb enlargement. The scratch is elicited by applying gentle tactile stimulation to a site innervated by spinal segments caudal to the level of the transection. During the sc...

journal_title：Journal of neurophysiology

authors： Mortin LI,Keifer J,Stein PS

更新日期：1985-06-01 00:00:00

abstract：:1. The present study was designed to determine the effects of microstimulation of the medullary reticular formation (MRF) on the locomotor activity of the cat in the absence of phasic afferent feedback from the limbs. To this end, both short (33 ms) and long (200 ms) trains of stimuli (trains of 0.2-ms pulses at 330 H...

journal_title：Journal of neurophysiology

authors： Perreault MC,Rossignol S,Drew T

更新日期：1994-01-01 00:00:00

abstract：:Our perception of the positions of objects in our surroundings is surprisingly unaffected by movements of the eyes, head, and body. This suggests that the brain has a mechanism for maintaining perceptual stability, based either on the spatial relationships among visible objects or internal copies of its own motor comm...

journal_title：Journal of neurophysiology

authors： Churan J,Guitton D,Pack CC

更新日期：2011-10-01 00:00:00

abstract：:Gain modulation is a ubiquitous phenomenon in cortical neurons, providing flexibility to operate under changing conditions. The prevailing view is that this modulation reflects a change in the relationship between mean input and output firing rate brought about by variation in neuronal membrane characteristics. An alt...

journal_title：Journal of neurophysiology

authors： Azouz R

更新日期：2005-10-01 00:00:00

abstract：:The R6/2 mouse is the most frequently used model for experimental and preclinical drug trials in Huntington's disease (HD). When the R6/2 mouse was first developed, it carried exon 1 of the huntingtin gene with ~150 cytosine-adenine-guanine (CAG) repeats. The model presented with a rapid and aggressive phenotype that ...

journal_title：Journal of neurophysiology

authors： Cummings DM,Alaghband Y,Hickey MA,Joshi PR,Hong SC,Zhu C,Ando TK,André VM,Cepeda C,Watson JB,Levine MS

更新日期：2012-01-01 00:00:00

abstract：:The reward value of a stimulus can be learned through two distinct mechanisms: reinforcement learning through repeated stimulus-reward pairings and abstract inference based on knowledge of the task at hand. The reinforcement mechanism is often identified with midbrain dopamine neurons. Here we show that a neural pathw...

journal_title：Journal of neurophysiology

authors： Bromberg-Martin ES,Matsumoto M,Hong S,Hikosaka O

更新日期：2010-08-01 00:00:00

abstract：:The role of potassium channels in regulating spontaneous firing and sound-evoked responses in the central nucleus of the inferior colliculus was studied by recording single-unit activity before and during iontophoretic application of a nonspecific potassium channel blocker, tetraethylammonium (TEA). Tone bursts and si...

journal_title：Journal of neurophysiology

authors： Zhang H,Wu SH,Kelly JB

更新日期：2004-05-01 00:00:00

abstract：:Fast oscillatory activity (more than approximately 200 Hz) has been attracting increasing attention regarding its possible role in both normal brain function and epileptogenesis. Yet, its underlying cellular mechanism remains poorly understood. Our prior investigation of the phenomenon in rat somatosensory cortex indi...

journal_title：Journal of neurophysiology

authors： Jones MS,Barth DS

更新日期：2002-08-01 00:00:00

abstract：:Some neurons in early visual cortex are highly selective for the position of oriented edges in their receptive fields (simple cells), whereas others are largely position insensitive (complex cells). These characteristics are reflected in their sensitivity to the spatial phase of moving sine-wave gratings: simple cell ...

journal_title：Journal of neurophysiology

authors： Cloherty SL,Ibbotson MR

更新日期：2015-01-15 00:00:00

abstract：:Information about the position of an object that is held in both hands, such as a golf club or a tennis racquet, is transmitted to the human central nervous system from peripheral sensors in both left and right arms. How does the brain combine these two sources of information? Using a robot to move participant's passi...

journal_title：Journal of neurophysiology

authors： Wong JD,Wilson ET,Kistemaker DA,Gribble PL

更新日期：2014-03-01 00:00:00

abstract：:1. Responses of primary sensory neurons to substance P applications by perfusion were studied with intracellular recording techniques in in vitro slice preparations of trigeminal root ganglia (guinea pigs). Application of substance P in micromolar doses produced reversible depolarizations of 2-47 mV in 48 out of 64 ne...

journal_title：Journal of neurophysiology

authors： Spigelman I,Puil E

更新日期：1990-07-01 00:00:00

abstract：:Intracellular Ca2+ is influenced by both Ca2+ influx and release. We examined intracellular Ca2+ following action potential firing in the bag cell neurons of Aplysia californica. Following brief synaptic input, these neuroendocrine cells undergo an afterdischarge, resulting in elevated Ca2+ and the secretion of neurop...

journal_title：Journal of neurophysiology

authors： Geiger JE,Magoski NS

更新日期：2008-07-01 00:00:00

abstract：:1. We studied the effect of electrical stimulation of the peribrachial region (PBR) in the brain stem on the visual response of single cells in the dorsal lateral geniculate nucleus (dLGN) to a light slit presented in a series of positions across the receptive field. The response was plotted against slit position, giv...

journal_title：Journal of neurophysiology

authors： Hartveit E,Ramberg SI,Heggelund P

更新日期：1993-10-01 00:00:00

abstract：:1. Presynaptic activity of identified primary afferents from flexor, extensor, and bifunctional hindlimb muscles was studied with intra-axonal recordings during fictive locomotion. Fictive locomotion appeared spontaneously in decorticate cats (n = 9), with stimulation of the mesencephalic locomotor region (n = 4), and...

journal_title：Journal of neurophysiology

authors： Gossard JP,Cabelguen JM,Rossignol S

更新日期：1991-04-01 00:00:00

abstract：:Behavioral performance in detection and discrimination tasks is likely to be limited by the quality and nature of the signals carried by populations of neurons in early sensory cortical areas. Here we used voltage-sensitive dye imaging (VSDI) to directly measure neural population responses in the primary visual cortex...

journal_title：Journal of neurophysiology

authors： Chen Y,Geisler WS,Seidemann E

更新日期：2008-03-01 00:00:00

abstract：:Sensory neurons appear to adapt their gain to match the variance of signals along the dimension they encode, a property we shall call "contrast normalization." Contrast normalization has been the subject of extensive physiological and theoretical study. We previously found that neurons in the lateral geniculate nucleu...

journal_title：Journal of neurophysiology

authors： Gaudry KS,Reinagel P

更新日期：2007-09-01 00:00:00

abstract：:Extracellular recordings of 209 neurons were obtained with carbon fiber-containing multibarrel micropipettes. The cells were isolated in the primary somatosensory cortex of cats anesthetized with barbiturate and classified according to the nature of their response to natural stimuli, the nature of the surrounding mult...

journal_title：Journal of neurophysiology

authors： Dykes RW,Landry P,Metherate R,Hicks TP

更新日期：1984-12-01 00:00:00

abstract：:The holoplanktonic pteropod mollusk Clione limacina exhibits an active escape behavior that is characterized by fast swimming away from the source of potentially harmful stimuli. The initial phase of escape behavior is a startle response that is controlled by pedal motoneurons whose activity is independent of the norm...

journal_title：Journal of neurophysiology

authors： Norekian TP,Satterlie RA

更新日期：1997-01-01 00:00:00

abstract：:The inhibitory circuits of the striatum are known to be critical for motor function, yet their contributions to Parkinsonian motor deficits are not clear. Altered firing in the globus pallidus suggests that striatal medium spiny neurons (MSN) of the direct (D1 MSN) and indirect pathway (D2 MSN) are imbalanced during d...

journal_title：Journal of neurophysiology

authors： Damodaran S,Evans RC,Blackwell KT

更新日期：2014-02-01 00:00:00

abstract：:Controlled whisker stimulation and single-unit recordings were used to elucidate response transformations that occur during the processing of tactile information from ventral posterior medial thalamus (VPM) through cortical columns in the rat whisker/barrel cortex. Whiskers were either deflected alone, using punctate ...

journal_title：Journal of neurophysiology

authors： Brumberg JC,Pinto DJ,Simons DJ

更新日期：1999-10-01 00:00:00

abstract：:1. Neurons in the ventral intraparietal area (VIP) are known to respond to translating random dot patterns. Such responses can be explained on the basis of the input of the middle temporal area (MT) to this area. Anatomic evidence has shown that VIP receives input from the dorsal part of the medial superior temporal a...

journal_title：Journal of neurophysiology

authors： Schaafsma SJ,Duysens J

更新日期：1996-12-01 00:00:00

abstract：:Pentobarbital, a general anesthetic, has received extensive study for its ability to potentiate inhibition at GABA(A) subtype of receptors for GABA. Using whole cell current-clamp techniques and bath applications, we determined the effects of pentobarbital and GABA receptor antagonists on the membrane properties and t...

journal_title：Journal of neurophysiology

authors： Wan X,Puil E

更新日期：2002-12-01 00:00:00

abstract：:Outward K+ currents were recorded using a whole cell patch-clamp configuration, from acutely dissociated adult rat cutaneous afferent dorsal root ganglion (DRG) neurons (L4 and L5) identified by retrograde labeling with Fluoro-gold. Recordings were obtained 16-24 h after dissociation from cells between 39 and 49 mm in...

journal_title：Journal of neurophysiology

authors： Everill B,Rizzo MA,Kocsis JD

更新日期：1998-04-01 00:00:00

abstract：:The process of sensorimotor adaptation is considered to be driven by errors. While sensory prediction errors, defined as the difference between the planned and the actual movement of the cursor, drive implicit learning processes, target errors (e.g., the distance of the cursor from the target) are thought to drive exp...

journal_title：Journal of neurophysiology

authors： Reichenthal M,Avraham G,Karniel A,Shmuelof L

更新日期：2016-08-01 00:00:00

abstract：:Neural oscillations are observed ubiquitously in the mammalian brain, but their stability is known to be rather variable. Some oscillations are tonic and last for seconds or even minutes. Other oscillations appear as unstable bursts. Likewise, some oscillations rely on excitatory AMPAergic synapses, but others are GAB...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Voytek B

更新日期：2020-07-01 00:00:00

abstract：:1. Synaptic responses of medial nucleus tractus solitarius (mNTS) neurons to solitary tract (ST) activation were studied in a horizontal brain slice preparation of the rat medulla. Slices included sections of ST sufficiently long that the ST could be electrically activated several millimeters from the recording site o...

journal_title：Journal of neurophysiology

authors： Andresen MC,Yang M

更新日期：1995-10-01 00:00:00