Abstract:
:The performance of neural codes to represent attributes of sensory signals has been evaluated in the vertebrate peripheral and central nervous system. Here, we determine how information signaled by populations of neurons is modified by plasticity. Suprathreshold neuronal responses from a large number of neurons were recorded in the juvenile mouse barrel cortex using dithered random-access scanning. Pairing of one input with another resulted in a long-lasting, input-specific modification of the cortical responses. Mutual information analysis indicated that cortical plasticity efficiently changed information signaled by populations of neurons. The contribution of neural correlations to the change in mutual information was negative. The largest factor limiting fidelity of mutual information after pairing was a low reliability of the modified cortical responses.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Pita-Almenar JD,Ranganathan GN,Koester HJdoi
10.1152/jn.01001.2010subject
Has Abstractpub_date
2011-09-01 00:00:00pages
1118-24issue
3eissn
0022-3077issn
1522-1598pii
jn.01001.2010journal_volume
106pub_type
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