Windup of flexion reflexes in chronic human spinal cord injury: a marker for neuronal plateau potentials?

abstract：:Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rat...

journal_title：Journal of neurophysiology

authors： Moorman DE,Olson CR

更新日期：2007-05-01 00:00:00

abstract：:In the auditory system of the big brown bat (Eptesicus fuscus), paired conditioned tonal (CS) and unconditioned leg stimuli (US) for auditory fear conditioning elicit tone-specific plasticity represented by best-frequency (BF) shifts that are augmented by acetylcholine, whereas unpaired CS and US for pseudoconditionin...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N

更新日期：2013-02-01 00:00:00

abstract：:The external anal sphincter (EAS) is important for the maintenance of bowel continence and may be compromised by a variety of neuropathic conditions. However, large animal models for the study of EAS functions have been sparse. The EAS guarding reflex was examined by electromyography (EMG) in neurologically intact rhe...

journal_title：Journal of neurophysiology

authors： Chang HH,Lee U,Vu T,Pikov V,Nieto JH,Christe KL,Havton LA

更新日期：2018-12-01 00:00:00

abstract：:Locusts have two large collision-detecting neurons, the descending contralateral movement detectors (DCMDs) that signal object approach and trigger evasive glides during flight. We sought to investigate whether vision for action, when the locust is in an aroused state rather than a passive viewer, significantly alters...

journal_title：Journal of neurophysiology

authors： Rind FC,Santer RD,Wright GA

更新日期：2008-08-01 00:00:00

abstract：:The ability of 17 cats to discriminate floor temperatures 2-4 degrees C below the ambient temperature was tested before and after unilateral electrolytic thalamic lesions. The lesions were made contralateral to the paws showing better performance in the temperature discrimination task. They were aimed at one or more o...

journal_title：Journal of neurophysiology

authors： Norrsell U,Craig AD

更新日期：1999-08-01 00:00:00

abstract：:Cell-surface glutamate transporters are essential for the proper function of early cortical networks because their dysfunction induces seizures in the newborn rat in vivo. We have now analyzed the consequences of their inhibition by DL-TBOA on the activity of the developing CA1 rat hippocampal network in vitro. DL-TBO...

journal_title：Journal of neurophysiology

authors： Cattani AA,Bonfardin VD,Represa A,Ben-Ari Y,Aniksztejn L

更新日期：2007-10-01 00:00:00

abstract：:This study aimed to determine whether individuals with spastic diplegic cerebral palsy (SDCP) have deficits in anticipatory inhibition of postural muscle activity. Nine individuals with SDCP (SDCP group, 3 female and 6 male, 13-24 yr of age) and nine age- and sex-matched individuals without disability (control group) ...

journal_title：Journal of neurophysiology

authors： Tomita H,Fukaya Y,Totsuka K,Tsukahara Y

更新日期：2013-04-01 00:00:00

abstract：:When they are 1-2 mo old, domesticated Mongolian gerbils begin having initially mild seizures which become more severe with age. To evaluate the development of this increasing seizure severity, we obtained field potential responses of the dentate gyrus to paired-pulse stimulation of the perforant path during seizures....

journal_title：Journal of neurophysiology

authors： Buckmaster PS,Wong EH

更新日期：2002-08-01 00:00:00

abstract：:Using intrinsic signal optical imaging (ISI), we have shown previously that the point spread of evoked activity in the rat barrel cortex in response to single-whisker stimulation encompasses a surprisingly large area. Given that our typical stimulation consists of five deflections at 5 Hz, the large area of evoked act...

journal_title：Journal of neurophysiology

authors： Polley DB,Chen-Bee CH,Frostig RD

更新日期：1999-02-01 00:00:00

abstract：:Cross-orientation suppression was measured in human primary visual cortex (V1) to test the normalization model. Subjects viewed vertical target gratings (of varying contrasts) with or without a superimposed horizontal mask grating (fixed contrast). We used functional magnetic resonance imaging (fMRI) to measure the ac...

journal_title：Journal of neurophysiology

authors： Brouwer GJ,Heeger DJ

更新日期：2011-11-01 00:00:00

abstract：:Stability of images on the retina was determined in 14 normal humans in response to rotational and translational perturbations during self-generated pitch and yaw, standing, walking, and running on a treadmill. The effects on image stability of target distance, vision, and spectacle magnification were examined. During...

journal_title：Journal of neurophysiology

authors： Crane BT,Demer JL

更新日期：1997-10-01 00:00:00

abstract：:Cognitive and motor deficits associated with language and speech are seen in humans harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are thought to reside in structural abnormalities distributed across systems important for language and motor learning including the cerebral cortex, basal...

journal_title：Journal of neurophysiology

authors： Miller JE,Spiteri E,Condro MC,Dosumu-Johnson RT,Geschwind DH,White SA

更新日期：2008-10-01 00:00:00

abstract：:Modulation of sacral spinal dorsal horn neurons by the ventrolateral PAG was studied by extracellular recording combined with microiontophoretic applications of alpha-adrenergic agonists or antagonists. Bicuculline (BIC, 15 ng) microinjected into the ventrolateral PAG produced a consistent inhibition of the responses ...

journal_title：Journal of neurophysiology

authors： Budai D,Harasawa I,Fields HL

更新日期：1998-11-01 00:00:00

abstract：:1. Two subtypes of astrocytes that expressed distinctly different ion channel complements were identified in primary cultures from rat spinal cord and hippocampus using whole cell patch-clamp techniques. One population of cells expressed voltage-activated Na+ currents and displayed outwardly rectifying I-V relationshi...

journal_title：Journal of neurophysiology

authors： Ransom CB,Sontheimer H,Janigro D

更新日期：1996-07-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) can potentiate synaptic release at newly developed frog neuromuscular junctions. Although this potentiation depends on extracellular Ca(2+) and reflects changes in acetylcholine release, little is known about the intracellular transduction or calcium signaling pathways. We have...

journal_title：Journal of neurophysiology

authors： Kleiman RJ,Tian N,Krizaj D,Hwang TN,Copenhagen DR,Reichardt LF

更新日期：2000-07-01 00:00:00

abstract：:The purpose of these studies was to determine the role of gracile nucleus and the effects of l-arginine-derived nitric oxide (NO) synthesis in the nucleus on the cardiovascular responses to electroacupuncture (EA) stimulation of "Zusanli" (ST36). Arterial blood pressure and heart rate were monitored during EA stimulat...

journal_title：Journal of neurophysiology

authors： Chen S,Ma SX

更新日期：2003-08-01 00:00:00

abstract：:The holoplanktonic pteropod mollusk Clione limacina exhibits an active escape behavior that is characterized by fast swimming away from the source of potentially harmful stimuli. The initial phase of escape behavior is a startle response that is controlled by pedal motoneurons whose activity is independent of the norm...

journal_title：Journal of neurophysiology

authors： Norekian TP,Satterlie RA

更新日期：1997-01-01 00:00:00

abstract：:Human neuropsychological and neuroimaging studies have raised the possibility that different attributes of optic flow stimuli, namely radial direction and the position of the focus of expansion (FOE), are processed within separate cortical areas. In the human brain, visual areas V5/MT+ and V3A have been proposed as in...

journal_title：Journal of neurophysiology

authors： Strong SL,Silson EH,Gouws AD,Morland AB,McKeefry DJ

更新日期：2017-06-01 00:00:00

abstract：:Fast inhibitory synaptic transmission in the brain relies on ionotropic GABA(A) receptors (GABA(A)R). Eighteen genes code for GABA(A)R subunits, but little is known about the epsilon subunit. Our aim was to identify the synaptic transmission properties displayed by native receptors incorporating epsilon. Immunogold lo...

journal_title：Journal of neurophysiology

authors： Belujon P,Baufreton J,Grandoso L,Boué-Grabot E,Batten TF,Ugedo L,Garret M,Taupignon AI

更新日期：2009-10-01 00:00:00

abstract：:Adaptation of fingertip forces to friction at the grasping surface is necessary to prevent use of inadequate or excessive grip forces. In the current study we investigated the effect of blocking tactile information from the fingertips noninvasively on the adaptation and efficiency of grip forces to surface friction du...

journal_title：Journal of neurophysiology

authors： Bilaloglu S,Lu Y,Geller D,Rizzo JR,Aluru V,Gardner EP,Raghavan P

更新日期：2016-03-01 00:00:00

abstract：:Single-unit recordings were made from layer II/III anterior piriform cortex (aPCX) neurons in adult Wistar rats to examine odor response patterns to unilaterally and bilaterally delivered stimuli. Isoamyl acetate odor stimulation was presented either unilaterally through tubes inserted into the external nares, or bila...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：1997-07-01 00:00:00

abstract：:1. The somatotopic organization of nociceptive-specific (NS) and wide dynamic range (WDR) units in the nucleus ventralis posterolateralis (VPL) of the ventrobasal (VB) complex was studied. Experiments were carried out on adult cats anesthetized with urethane-chloralose. The recording sites of nociceptive units were ma...

journal_title：Journal of neurophysiology

authors： Yokota T,Asato F,Koyama N,Masuda T,Taguchi H

更新日期：1988-11-01 00:00:00

abstract：:Procedural skill learning requires iterative comparisons between feedback of self-generated motor output and a goal sensorimotor pattern. In juvenile songbirds, neural representations of both self-generated behaviors (each bird's own immature song) and the goal motor pattern (each bird's adult tutor song) are essentia...

journal_title：Journal of neurophysiology

authors： Yuan RC,Bottjer SW

更新日期：2019-02-01 00:00:00

abstract：:1. The electrical responses of nociceptive (N) lateral and N medial neurons of the leech segmental ganglion to mechanical, chemical, and thermal stimulation of the skin were studied in a superfused ganglion-body wall preparation. 2. Mechanical indentation of the skin > 10 mN evoked in both types of cells a sustained d...

journal_title：Journal of neurophysiology

authors： Pastor J,Soria B,Belmonte C

更新日期：1996-06-01 00:00:00

abstract：:We investigated adaptation to simple force field scaling to determine whether the same strategy is used as during adaptation to more complex changes in the mechanical environment. Subjects initially trained in a force field, consisting of a rightward lateral force with a parabolic spatial profile (PF). The field stren...

journal_title：Journal of neurophysiology

authors： Hinder MR,Milner TE

更新日期：2007-11-01 00:00:00

abstract：:The excitotoxic theory of Parkinson's disease (PD) hypothesizes that a pathophysiological degeneration of dopaminergic neurons stems from neural hyperactivity at early stages of disease, leading to mitochondrial stress and cell death. Recent research has harnessed the visual system of Drosophila PD models to probe thi...

journal_title：Journal of neurophysiology

authors： Himmelberg MM,West RJH,Elliott CJH,Wade AR

更新日期：2018-03-01 00:00:00

abstract：:The problem of how the nervous system fuses sensory information from multiple modalities for upright stance control remains largely unsolved. It is well established that the visual, vestibular, and somatosensory modalities provide position and rate (e.g., velocity, acceleration) information for estimation of body dyna...

journal_title：Journal of neurophysiology

authors： Jeka J,Kiemel T,Creath R,Horak F,Peterka R

更新日期：2004-10-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) receives a dense serotonergic innervation that modulates photic input to the SCN via serotonin 1B (5-HT1B) presynaptic receptors on retinal glutamatergic terminals. However, the majority of 5-HT1B binding sites in the SCN are located on nonretinal terminals and most axonal terminals i...

journal_title：Journal of neurophysiology

authors： Bramley JR,Sollars PJ,Pickard GE,Dudek FE

更新日期：2005-06-01 00:00:00

abstract：:Nonsynaptic mechanisms exert a powerful influence on seizure threshold. It is well-established that nonsynaptic epileptiform activity can be induced in hippocampal slices by reducing extracellular Ca(2+) concentration. We show here that nonsynaptic epileptiform activity can be readily induced in vitro in normal (2 mM)...

journal_title：Journal of neurophysiology

authors： Bikson M,Baraban SC,Durand DM

更新日期：2002-01-01 00:00:00

abstract：:Internally generated, spontaneous activity is ubiquitous in the cortex, yet it does not appear to have a significant negative impact on sensory processing. Various studies have found that stimulus onset reduces the variability of cortical responses, but the characteristics of this suppression remained unexplored. By r...

journal_title：Journal of neurophysiology

authors： White B,Abbott LF,Fiser J

更新日期：2012-11-01 00:00:00