Ventral pallidum firing codes hedonic reward: when a bad taste turns good.

abstract：:Experience-dependent modification in the electrical properties of central neurons is a form of intrinsic plasticity that occurs during development and has been observed following behavioral learning. We report a novel form of intrinsic plasticity in hippocampal CA1 pyramidal neurons mediated by the KV7/KCNQ and CaV1/L...

journal_title：Journal of neurophysiology

authors： Wu WW,Chan CS,Surmeier DJ,Disterhoft JF

更新日期：2008-10-01 00:00:00

abstract：:The last few years have seen an increase in the variety of in vivo experiments used for studying cerebellar physiological mechanisms. A combination of ketamine and xylazine has become a particularly popular form of anesthesia. However, because nonanesthetized control conditions are lacking in these experiments, so far...

journal_title：Journal of neurophysiology

authors： Bengtsson F,Jörntell H

更新日期：2007-09-01 00:00:00

abstract：:High-frequency activity produces transient depression at many synapses but also, as recently demonstrated, may accelerate the recovery from use-dependent depression. We have examined the possible consequences of this synaptic mechanism in neocortical excitatory synapses by recording simultaneously from presynaptic pyr...

journal_title：Journal of neurophysiology

authors： Galarreta M,Hestrin S

更新日期：2000-01-01 00:00:00

abstract：:The auditory frequency-following response (FFR) reflects synchronized and phase-locked activity along the auditory pathway in response to sound. Although FFRs were historically thought to reflect subcortical activity, recent evidence suggests an auditory cortex contribution as well. Here we present electrophysiologica...

journal_title：Journal of neurophysiology

authors： White-Schwoch T,Anderson S,Krizman J,Nicol T,Kraus N

更新日期：2019-08-01 00:00:00

abstract：:Caenorhabditis elegans responds to chemical cues using a small number of chemosensory neurons that detect a large variety of molecules in its environment. During chemotaxis, C. elegans biases its migration in spatial chemical gradients by lengthening (/shortening) periods of forward movement when it happens to be movi...

journal_title：Journal of neurophysiology

authors： Luo L,Gabel CV,Ha HI,Zhang Y,Samuel AD

更新日期：2008-05-01 00:00:00

abstract：:Studies on generalization show the nature of how learning is encoded in the brain. Previous studies have shown rather limited generalization of dynamics learning across changes in movement direction, a finding that is consistent with the idea that learning is primarily local. In contrast, studies show a broader patter...

journal_title：Journal of neurophysiology

authors： Mattar AA,Ostry DJ

更新日期：2010-07-01 00:00:00

abstract：:1. The alignment of the pupillary axes and of the visual axes has been measured in 23 normally reared cats ranging in age from 14 days to adulthood. 2. In agreement with a previous report, we find that pupillary divergence, as measured from photographs, tends to decrease during the first 2 mo of life. 3. The angle bet...

journal_title：Journal of neurophysiology

authors： Olson CR,Freeman RD

更新日期：1978-07-01 00:00:00

abstract：:1. Baclofen increases transient light responses of amacrine and ganglion cells despite acting as a classical inhibitory transmitter to both hyperpolarize and shunt these cells. 2. This effect seems to occur at the level of the inner retina and appears not to be due to an additional input from bipolar cells. 3. In some...

journal_title：Journal of neurophysiology

authors： Bai SH,Slaughter MM

更新日期：1989-02-01 00:00:00

abstract：:Previous studies have demonstrated anisotropic patterns of hand impedance under static conditions and during movement. Here we show that the pattern of kinematic error observed in studies of dynamics learning is associated with this anisotropic impedance pattern. We also show that the magnitude of kinematic error asso...

journal_title：Journal of neurophysiology

authors： Darainy M,Mattar AA,Ostry DJ

更新日期：2009-06-01 00:00:00

abstract：:Odor responses of neocortical neurons in rabbits under light pentobarbital anesthesia were studied in a restricted area in the lateral half of the prefrontal cortex close to the frontal pole. A preevent cumulative sum chart provided a visual display of the change in unit discharge rate following each odor stimulation,...

journal_title：Journal of neurophysiology

authors： Onoda N,Imamura K,Obata E,Iino M

更新日期：1984-10-01 00:00:00

abstract：:Neural activity was recorded in the parietooccipital cortex while monkeys performed different tasks aimed at investigating visuomotor interactions of retinal, eye, and arm-related signals on neural activity. The tasks were arm reaching 1) to foveated targets; 2) to extrafoveal targets, with constant eye position; 3) w...

journal_title：Journal of neurophysiology

authors： Battaglia-Mayer A,Ferraina S,Mitsuda T,Marconi B,Genovesio A,Onorati P,Lacquaniti F,Caminiti R

更新日期：2000-04-01 00:00:00

abstract：:The nucleus accumbens core (AcbC) is a striatal brain region essential for integrating motivated behavior and reward processing with premotor function. In humans and rodents, research has identified sex differences and sex steroid hormone sensitivity in AcbC-mediated behaviors, in disorders, and in rats in the electro...

journal_title：Journal of neurophysiology

authors： Cao J,Dorris DM,Meitzen J

更新日期：2018-10-01 00:00:00

abstract：:Perceptual decision making is often modeled as perfect integration of sequential sensory samples until the accumulated total reaches a fixed decision bound. In that view, the buildup of neural activity during perceptual decision making is attributed to temporal integration. However, an alternative explanation is that ...

journal_title：Journal of neurophysiology

authors： Carland MA,Marcos E,Thura D,Cisek P

更新日期：2016-02-01 00:00:00

abstract：:1. The capacity for judging the location of an object relative to the body (egocentric localization) was assessed in cats by measuring the landing position attained when the cat jumped toward a platform viewed from a known distance. 2. Normal cats and kittens land at center of the platform when using one eye or both. ...

journal_title：Journal of neurophysiology

authors： Olson CR

更新日期：1980-03-01 00:00:00

abstract：:This study examined the effects of selective inactivation of the cerebellar nuclei in the cat on the control of multijoint trajectories and trajectory adaptation to avoid obstacles. Animals were restrained in a hammock and trained to perform a prehension task in which they reached to grasp a small cube of meat from a ...

journal_title：Journal of neurophysiology

authors： Martin JH,Cooper SE,Hacking A,Ghez C

更新日期：2000-04-01 00:00:00

abstract：:1. K+ conductances were characterized in isolated, identified superior colliculus-projecting (SCP) rat visual cortical neurons. SCP neurons were identified in vitro under epifluorescence illumination after in vivo retrograde labeling with rhodamine-labeled microspheres or "beads." For experiments, SCP neurons were iso...

journal_title：Journal of neurophysiology

authors： Albert JL,Nerbonne JM

更新日期：1995-06-01 00:00:00

abstract：:A consistent feature of animal locomotion is the capacity to maintain stable movements in changing environments. Here we describe long-term modification of the swing movement of the hind leg in cats in response to repeatedly impeding the movement of the leg. While studying phase transitions in the hind legs, we discov...

journal_title：Journal of neurophysiology

authors： McVea DA,Pearson KG

更新日期：2007-01-01 00:00:00

abstract：:The experiments described in this report were designed to determine the contribution of vestibulospinal neurons (VSNs) in Deiters' nucleus and of reticulospinal neurons (RSNs) in the medullary reticular formation to the modifications of the walking pattern that are associated with locomotion on an inclined plane. Neur...

journal_title：Journal of neurophysiology

authors： Matsuyama K,Drew T

更新日期：2000-11-01 00:00:00

abstract：:1. Dim backgrounds can enhance small-spot flicker responses of cat retinal horizontal cells by a factor of 2 or more. 2. Intracellular marking with horseradish peroxidase (HRP) reveals that this enhancement effect occurs in--but is not necessarily limited to--the cone-connected, A-type horizontal cell. 3. Flicker ampl...

journal_title：Journal of neurophysiology

authors： Pflug R,Nelson R,Ahnelt PK

更新日期：1990-08-01 00:00:00

abstract：:In this study, the representation of taste in the orbitofrontal cortex was investigated to determine whether or not a pleasant and an aversive taste have distinct or overlapping representations in this region. The pleasant stimulus used was sweet taste (1 M glucose), and the unpleasant stimulus was salt taste (0.1 M N...

journal_title：Journal of neurophysiology

authors： O'Doherty J,Rolls ET,Francis S,Bowtell R,McGlone F

更新日期：2001-03-01 00:00:00

abstract：:1. The little brown bat, Myotis lucifugus, employs biosonar pulses containing broadband frequency-modulated (FM) sounds of only one harmonic during the initial phases of echolocation. Neurons throughout the auditory cortex exhibit delay-dependent facilitation to artificial pulses and echoes at particular echo delays. ...

journal_title：Journal of neurophysiology

authors： Paschal WG,Wong D

更新日期：1994-07-01 00:00:00

abstract：:To localize objects relative to ourselves, we need to combine various sensory and motor signals. When these signals change abruptly, as information about eye orientation does during saccades, small differences in latency between the signals could introduce localization errors. We examine whether independent temporal i...

journal_title：Journal of neurophysiology

authors： Maij F,Brenner E,Smeets JB

更新日期：2009-07-01 00:00:00

abstract：:Robust auditory perception plays a pivotal function for processing behaviorally relevant sounds, particularly with distractions from the environment. The neuronal coding enabling this ability, however, is still not well understood. In this study, we recorded single-unit activity from the primary auditory cortex (A1) o...

journal_title：Journal of neurophysiology

authors： Ni R,Bender DA,Shanechi AM,Gamble JR,Barbour DL

更新日期：2017-02-01 00:00:00

abstract：:1. The preceding study described a corrective response in cats when one hind leg steps into a hole. In this investigation we examine the extent to which this behavior is organized at the spinal level by comparing the responses elicited in intact and chronic spinal cats. 2. Adult cats were trained to step bipedally wit...

journal_title：Journal of neurophysiology

authors： Hiebert GW,Gorassini MA,Jiang W,Prochazka A,Pearson KG

更新日期：1994-02-01 00:00:00

abstract：:Previous behavioral work has shown the existence of both anticipatory and reactive grip force responses to predictable load perturbations, but how the brain implements anticipatory control remains unclear. Here we recorded electroencephalographs while participants were subjected to predictable and unpredictable extern...

journal_title：Journal of neurophysiology

authors： Kourtis D,Kwok HF,Roach N,Wing AM,Praamstra P

更新日期：2008-02-01 00:00:00

abstract：:Sensory inputs from muscle, cutaneous, and joint afferents project to the spinal cord, where they are able to affect ongoing locomotor activity. Activation of sensory input can initiate or prolong bouts of locomotor activity depending on the identity of the sensory afferent activated and the timing of the activation w...

journal_title：Journal of neurophysiology

authors： Bui TV,Brownstone RM

更新日期：2015-04-01 00:00:00

abstract：:These experiments were designed to test the hypothesis that climbing fiber inputs evoked by a peripheral stimulus increase the responsiveness of Purkinje cells to mossy fiber inputs. This hypothesis was based on a previous series of observations demonstrating that spontaneous climbing fiber inputs are associated with ...

journal_title：Journal of neurophysiology

authors： Ebner TJ,Yu QX,Bloedel JR

更新日期：1983-07-01 00:00:00

abstract：:Paired-pulse transcranial magnetic stimulation (TMS) and peripheral stimulation combined with TMS can be used to study cortical interneuronal circuitry. By combining these procedures with concurrent transcranial alternating current stimulation (tACS), Guerra and colleagues recently showed that different cortical inter...

journal_title：Journal of neurophysiology

authors： Hussain SJ,Thirugnanasambandam N

更新日期：2017-06-01 00:00:00

abstract：:Cervical dystonia (CD) is a movement disorder that involves involuntary turning and twisting of the neck caused by abnormal muscle contraction. Deep brain stimulation (DBS) in the globus pallidus internus (GPi) is used to treat both CD and the motor symptoms of Parkinson's disease (PD). It has been suggested that the ...

journal_title：Journal of neurophysiology

authors： Tang JK,Moro E,Mahant N,Hutchison WD,Lang AE,Lozano AM,Dostrovsky JO

更新日期：2007-08-01 00:00:00

abstract：:It has been suggested that the motor system may circumvent the difficulty of controlling many degrees of freedom in the musculoskeletal apparatus by generating motor outputs through a combination of discrete muscle synergies. How a discretely organized motor system compensates for diverse perturbations has remained el...

journal_title：Journal of neurophysiology

authors： Cheung VC,d'Avella A,Bizzi E

更新日期：2009-03-01 00:00:00