Activity-dependent plasticity improves M1 motor representation and corticospinal tract connectivity.

abstract：:1. We investigated gamma-aminobutyric acid (GABA) receptors using thin slice patch-clamp techniques in the swellings along axons of posterior pituitary nerve terminals. 2. Activation of the nerve terminal GABAA receptor induced a mean conductance change of 1.5 nS. Normalizing to area gave a mean conductance density of...

journal_title：Journal of neurophysiology

authors： Zhang SJ,Jackson MB

更新日期：1995-03-01 00:00:00

abstract：:The responsiveness of sensory neurons to muscle metabolites is altered under the conditions of insufficient limb blood supply in some diseases, such as peripheral artery disease. The purpose of this study was to examine ATP-induced current with activation of purinergic P2X subtypes P2X₃ and P2X₂/₃ in dorsal root gangl...

journal_title：Journal of neurophysiology

authors： Xing J,Lu J,Li J

更新日期：2013-04-01 00:00:00

abstract：:Reach-to-grasp movements require information about the distance and size of target objects. Calibration of this information could be achieved via feedback information (visual and/or haptic) regarding terminal accuracy when target objects are grasped. A number of reports suggest that the nervous system alters reach-to-...

journal_title：Journal of neurophysiology

authors： Bingham GP,Mon-Williams MA

更新日期：2013-12-01 00:00:00

abstract：:Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of t...

journal_title：Journal of neurophysiology

authors： Jimenez LO,Tring E,Trachtenberg JT,Ringach DL

更新日期：2018-07-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:Endocannabinoids are lipid derivatives that mediate paracrine and juxtacrine signaling between cells. In the hippocampal CA1 region, a retrograde endocannabinoid signal suppresses GABA release by acting on presynaptic cannabinoid receptor-1 (CB1) and can be functionally manifested as depolarization-induced suppression...

journal_title：Journal of neurophysiology

authors： Zhu PJ,Lovinger DM

更新日期：2010-02-01 00:00:00

abstract：:There is evidence that postural instability associated with Parkinson's disease (PD) is not adequately improved by levodopa, implying involvement of nondopaminergic pathways. However, the mechanisms contributing to postural instability have yet to be fully identified and tested for their levodopa responsiveness. In th...

journal_title：Journal of neurophysiology

authors： Di Giulio I,St George RJ,Kalliolia E,Peters AL,Limousin P,Day BL

更新日期：2016-08-01 00:00:00

abstract：:During auditory stimulation with several frequency components, distortion products (DPs) are generated as byproduct of nonlinear cochlear amplification. After generated, DP energy is reemitted into the ear channel where it can be measured as DP otoacoustic emission (DPOAE), and it also induces an excitatory response a...

journal_title：Journal of neurophysiology

authors： Abel C,Kössl M

更新日期：2009-03-01 00:00:00

abstract：:To examine the activity of somatosensory cortex (S1) neurons to self-generated shear forces on the index and thumb, two monkeys were trained to grasp a stationary metal tab with a key grip and exert forces without the fingers slipping in one of four orthogonal directions for 1 s. A majority (∼85%) of slowly adapting a...

journal_title：Journal of neurophysiology

authors： Fortier-Poisson P,Langlais JS,Smith AM

更新日期：2016-01-01 00:00:00

abstract：:Neurons in monkey orbitofrontal cortex (OF) are known to respond to reward-predicting cues with a strength that depends on the value of the predicted reward as determined 1) by intrinsic attributes including size and quality and 2) by extrinsic factors including the monkey's state of satiation and awareness of what ot...

journal_title：Journal of neurophysiology

authors： Roesch MR,Olson CR

更新日期：2005-10-01 00:00:00

abstract：:1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

journal_title：Journal of neurophysiology

authors： Surmeier DJ,Honda CN,Willis WD Jr

更新日期：1988-03-01 00:00:00

abstract：:Under constant light-adapted conditions, vision seems to be rather linear. However, the processes underlying the synaptic transmission between cones and second-order neurons (bipolar cells and horizontal cells) are highly nonlinear. In this paper, the gain-characteristics of the transmission from cones to horizontal c...

journal_title：Journal of neurophysiology

authors： Kraaij DA,Spekreijse H,Kamermans M

更新日期：2000-09-01 00:00:00

abstract：:1. The pteropod mollusk Clione limacina swims by rhythmical oscillations of two wings, and its spatial orientation during locomotion is determined by tail movements. The majority of neurons responsible for generation of the wing and tail movements are located in the pedal ganglia. On the other hand, the majority of se...

journal_title：Journal of neurophysiology

authors： Panchin YV,Popova LB,Deliagina TG,Orlovsky GN,Arshavsky YI

更新日期：1995-05-01 00:00:00

abstract：:Biological gain mechanisms regulate the sensitivity and dynamics of signaling pathways at the systemic, cellular, and molecular levels. In the sympathetic nervous system, gain in sensory-motor feedback loops is essential for homeostatic regulation of blood pressure and body temperature. This study shows how synaptic c...

journal_title：Journal of neurophysiology

authors： Wheeler DW,Kullmann PH,Horn JP

更新日期：2004-11-01 00:00:00

abstract：:Outward K+ currents were recorded using a whole cell patch-clamp configuration, from acutely dissociated adult rat cutaneous afferent dorsal root ganglion (DRG) neurons (L4 and L5) identified by retrograde labeling with Fluoro-gold. Recordings were obtained 16-24 h after dissociation from cells between 39 and 49 mm in...

journal_title：Journal of neurophysiology

authors： Everill B,Rizzo MA,Kocsis JD

更新日期：1998-04-01 00:00:00

abstract：:We have used the rat hippocampal slice preparation as a model system for studying the epileptogenic consequences of a reduction in neuronal Na+-K+ pump activity. The cardiac glycosides (CGs) strophanthidin and dihydroouabain were used to inhibit the pump. These drugs had readily reversible effects, provided they were ...

journal_title：Journal of neurophysiology

authors： McCarren M,Alger BE

更新日期：1987-02-01 00:00:00

abstract：:Are behaviors that rely on common muscles and motoneurons generated by separate or overlapping groups of pattern-generating neurons? This question was investigated for the three forms of scratching in immobilized, spinal turtles. Individual neurons were recorded extracellularly from the gray matter through most of the...

journal_title：Journal of neurophysiology

authors： Berkowitz A

更新日期：2001-08-01 00:00:00

abstract：:The effects of deep brain stimulation (DBS) on balance in people with Parkinson's disease (PD) are not well established. This study examined whether DBS randomized to the subthalamic nucleus (STN; n = 11) or globus pallidus interna (GPi; n = 10) improved compensatory stepping to recover balance after a perturbation. T...

journal_title：Journal of neurophysiology

authors： St George RJ,Carlson-Kuhta P,King LA,Burchiel KJ,Horak FB

更新日期：2015-09-01 00:00:00

abstract：:Previous studies of visual processing in humans using event-related potentials (ERPs) have demonstrated that task-related modulations of an early component called the "N1" wave (140-200 ms) reflect the operation of a voluntary discrimination process. Specifically, this component is larger in tasks requiring target dis...

journal_title：Journal of neurophysiology

authors： Hopf JM,Vogel E,Woodman G,Heinze HJ,Luck SJ

更新日期：2002-10-01 00:00:00

abstract：:We have recently demonstrated that application of the mustard oil (MO), a small-fiber excitant and inflammatory irritant, to the rat maxillary molar tooth pulp induces significant increases in jaw muscle electromyographic (EMG) activity and neuroplastic changes in trigeminal (V) subnucleus caudalis. Since subnucleus o...

journal_title：Journal of neurophysiology

authors： Park SJ,Chiang CY,Hu JW,Sessle BJ

更新日期：2001-05-01 00:00:00

abstract：:The capabilities of any sensory system are ultimately constrained by the properties of the sensory neurons: the ability to detect and represent stimuli is limited by noise due to spontaneous activity, and optimal decoding in downstream circuitry must be matched to the nature of the encoding performed at the input. Her...

journal_title：Journal of neurophysiology

authors： Arnson HA,Holy TE

更新日期：2011-07-01 00:00:00

abstract：:1. The purpose of this study is to analyze the kinematics of stepping from the point of view of limb control by attempting to dissociate the various neuronal and mechanical factors that shape actual movements observed experimentally. The cat hindlimb, like the primate arm, is a multijointed mechanical system with redu...

journal_title：Journal of neurophysiology

authors： Shen L,Poppele RE

更新日期：1995-12-01 00:00:00

abstract：:To understand the contribution of the human presupplementary motor area (pre-SMA) in sequential motor behavior, we performed a series of finger key-press experiments. Experiment 1 revealed that each subject had a spontaneous tendency to organize or "chunk" a long sequence into shorter components. We hypothesized that ...

journal_title：Journal of neurophysiology

authors： Kennerley SW,Sakai K,Rushworth MF

更新日期：2004-02-01 00:00:00

abstract：:1. This paper examines the electrophysiological properties of cultured rat adrenal chromaffin cells at different stages of neuron-like morphological differentiation in response to nerve growth factor (NGF). 2. Chromaffin cells display a large variability in the morphological changes after exposure to NGF. However, a m...

journal_title：Journal of neurophysiology

authors： Islas-Suárez L,Gómez-Chavarín M,Drucker-Colín R,Hernández-Cruz A

更新日期：1994-10-01 00:00:00

abstract：:Pyramidal cells in the dorsal cochlear nucleus (DCN) show three characteristic discharge patterns in response tones: pauser, buildup, and regular firing. Experimental evidence suggests that a rapidly inactivating K+ current (I(KIF)) plays a critical role in generating these discharge patterns. To explore the role of I...

journal_title：Journal of neurophysiology

authors： Kanold PO,Manis PB

更新日期：2001-02-01 00:00:00

abstract：:Propriospinal interneurons in the thoracic spinal cord have vital roles not only in controlling respiratory and trunk muscles, but also in providing possible substrates for recovery from spinal cord injury. Intracellular recordings were made from such interneurons in anesthetized cats under neuromuscular blockade and ...

journal_title：Journal of neurophysiology

authors： Saywell SA,Ford TW,Meehan CF,Todd AJ,Kirkwood PA

更新日期：2011-02-01 00:00:00

abstract：:Cutaneous application of painful radiant heat laser pulses evokes potentials (laser-evoked potentials) that can be recorded from scalp or intracranial electrodes. We have now tested the hypothesis that the response of thalamic neurons to a cutaneous laser stimulus occurs at latencies predicted by the conduction delay ...

journal_title：Journal of neurophysiology

authors： Kobayashi K,Winberry J,Liu CC,Treede RD,Lenz FA

更新日期：2009-05-01 00:00:00

abstract：:1. Locusts use a distinctive motor pattern to extend the tibia of a hind leg rapidly in a defensive kick, or to extend the tibiae of both hind legs in a jump. The force for the movement is generated by an almost isometric co-contraction of the extensor and flexor tibiae muscles followed by a sudden release of the stor...

journal_title：Journal of neurophysiology

authors： Hedwig B,Burrows M

更新日期：1996-03-01 00:00:00

abstract：:1. We studied the effect of temporarily inhibiting neurons in the caudal fastigial nucleus in two rhesus macaques trained to make saccades to jumping targets. We placed injections of the gamma-aminobutyric acid (GABA) agonist muscimol unilaterally or bilaterally at sites in the caudal fastigial nucleus where we had re...

journal_title：Journal of neurophysiology

authors： Robinson FR,Straube A,Fuchs AF

更新日期：1993-11-01 00:00:00

abstract：:Overestimation of roll tilt in hypergravity ("G-excess" illusion) has been demonstrated, but corresponding sustained hypogravic conditions are impossible to create in ground laboratories. In this article we describe the first systematic experimental evidence that in a hypogravity analog, humans underestimate roll tilt...

journal_title：Journal of neurophysiology

authors： Galvan-Garza RC,Clark TK,Sherwood D,Diaz-Artiles A,Rosenberg M,Natapoff A,Karmali F,Oman CM,Young LR

更新日期：2018-12-01 00:00:00