Ca(2+)-activated nonselective cationic current (I(CAN)) in turtle motoneurons.

abstract：:Cellular mechanisms underlying defense reactions induced by noxious heat and acids were studied in frogs (Rana pipiens) by measuring whole cell membrane currents in cultured dorsal root ganglion (DRG) neurons. Seventy-eight of 82 DRG neurons exposed to 3-s ramps of increasing temperature to 48 degrees C exhibited an i...

journal_title：Journal of neurophysiology

authors： Kuffler DP,Lyfenko A,Vyklický L,Vlachová V

更新日期：2002-10-01 00:00:00

abstract：:1. Serotonergic modulation of a hyperpolarization-activated inward current, Ih, and a calcium-dependent outward current, Io(Ca), was examined in the dorsal gastric (DG) motor neuron, with the use of intracellular recording techniques in an isolated preparation of the crab stomatogastric ganglion (STG). 2. Hyperpolariz...

journal_title：Journal of neurophysiology

authors： Kiehn O,Harris-Warrick RM

更新日期：1992-08-01 00:00:00

abstract：:Low-voltage-activated Ca(2+) currents (LVA-I(Ca)) are believed to perform several roles in neurons such as lowering the threshold for action potentials, promoting burst firing and oscillatory behavior, and enhancing synaptic excitation. They also may allow rapid increases in intracellular Ca(2+) concentration. We disc...

journal_title：Journal of neurophysiology

authors： Sekizawa SI,French AS,Torkkeli PH

更新日期：2000-02-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:1. R2 and LPl1 are homologous giant cholinergic neurons in the nervous system of Aplysia with overlapping and almost symmetrical axonal trees extending over most of the body wall. In spite of much experimental study, the behavioral role of the cells has remained unknown. 2. After intrasomatic injection of R2 and LPl1 ...

journal_title：Journal of neurophysiology

authors： Rayport SG,Ambron RT,Babiarz J

更新日期：1983-04-01 00:00:00

abstract：:Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radia...

journal_title：Journal of neurophysiology

authors： Klassen TL,Buckingham SD,Atherton DM,Dacks JB,Gallin WJ,Spencer AN

更新日期：2006-05-01 00:00:00

abstract：:Despite substantial advances in the field, particularly resulting from physiological studies in animals, the neural mechanisms underlying the generation of many motor behaviors in humans remain unclear. A recent study (Cappellini G et al. J Neurophysiol 104: 3064-3073, 2010) sheds more light on this topic. Like the st...

journal_title：Journal of neurophysiology

authors： Chiovetto E

更新日期：2011-04-01 00:00:00

abstract：:1. The response to an optimally oriented stimulus of both simple and complex cells in the cat's striate visual cortex (area 17) can be suppressed by the superposition of an orthogonally oriented drifting grating. This effect is referred to as cross-orientation suppression. We have examined the spatial organization and...

journal_title：Journal of neurophysiology

authors： DeAngelis GC,Robson JG,Ohzawa I,Freeman RD

更新日期：1992-07-01 00:00:00

abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...

journal_title：Journal of neurophysiology

authors： Valeyev AY,Hackman JC,Holohean AM,Wood PM,Katz JL,Davidoff RA

更新日期：1999-07-01 00:00:00

abstract：:1. Synaptic interactions between identified neurons in the flight system of the locust were investigated by the use of standard intracellular recording and staining techniques. The intent was to determine the distribution and functional significance of delayed excitatory connections, which have been previously describ...

journal_title：Journal of neurophysiology

authors： Robertson RM

更新日期：1991-05-01 00:00:00

abstract：:1. Extracellular and intracellular recordings from an isolated thoraco-abdominal preparation of the crayfish, Pacifastacus leniusculus, demonstrate that the swimmeret and the abdominal positioning systems can at times be spontaneously coordinated with each other. 2. Two forms of coordination were encountered between t...

journal_title：Journal of neurophysiology

authors： Chrachri A,Neil DM

更新日期：1993-05-01 00:00:00

abstract：:The responsiveness of sensory neurons to muscle metabolites is altered under the conditions of insufficient limb blood supply in some diseases, such as peripheral artery disease. The purpose of this study was to examine ATP-induced current with activation of purinergic P2X subtypes P2X₃ and P2X₂/₃ in dorsal root gangl...

journal_title：Journal of neurophysiology

authors： Xing J,Lu J,Li J

更新日期：2013-04-01 00:00:00

abstract：:Although species-specific differences in ion channel properties are well-documented, little has been known about the properties of the human Nav1.8 channel, an important contributor to pain signaling. Here we show, using techniques that include voltage clamp, current clamp, and dynamic clamp in dorsal root ganglion (D...

journal_title：Journal of neurophysiology

authors： Han C,Estacion M,Huang J,Vasylyev D,Zhao P,Dib-Hajj SD,Waxman SG

更新日期：2015-05-01 00:00:00

abstract：:Because the subthalamic nucleus (STN) acts as a driving force of the basal ganglia, it is important to know how the activities of STN neurons are regulated. Previously, we have reported that a subset of STN neurons generates a plateau potential in a voltage-dependent manner. These plateau potentials can be evoked only...

journal_title：Journal of neurophysiology

authors： Otsuka T,Abe T,Tsukagawa T,Song WJ

更新日期：2004-07-01 00:00:00

abstract：:Unitary discharge patterns (peristimulus time histograms or PSTH) and synaptic events were studies with intracellular recording techniques in 164 cat cochlear nucleus cells to steady-frequency tone bursts 250 ms in duration. There were four response types defined on the basis of the shape of the discharge patterns to ...

journal_title：Journal of neurophysiology

authors： Britt R,Starr A

更新日期：1976-01-01 00:00:00

abstract：:Feedback and descending projections from higher to lower brain centers play a prominent role in all vertebrate sensory systems. Feedback might be optimized for the specific sensory processing tasks in their target brain centers, but it has been difficult to connect the properties of feedback synapses to sensory tasks....

journal_title：Journal of neurophysiology

authors： Harvey-Girard E,Maler L

更新日期：2013-12-01 00:00:00

abstract：:In a subset of hereditary retinal diseases, early photoreceptor degeneration causes rapidly progressive blindness in children. To better understand how retinal development may interact with degenerative processes, we compared spontaneous and light-evoked activity among retinal ganglion cells in rd1 and rd10 mice, stra...

journal_title：Journal of neurophysiology

authors： Stasheff SF,Shankar M,Andrews MP

更新日期：2011-06-01 00:00:00

abstract：:1. We define an extrinsic frame of reference to represent the location of a point in extrapersonal space relative to a human subject's shoulder, and we define an intrinsic frame of reference to represent the orientation of the arm and forearm. 2. We examined the relations between coordinates in the extrinsic and intri...

journal_title：Journal of neurophysiology

authors： Soechting JF,Flanders M

更新日期：1989-08-01 00:00:00

abstract：:A large array of neuroscientific techniques, including in vivo electrophysiology, two-photon imaging, optogenetics, lesions, and microdialysis, require access to the brain through the skull. Ideally, the necessary craniotomies could be performed in a repeatable and automated fashion, without damaging the underlying br...

journal_title：Journal of neurophysiology

authors： Pak N,Siegle JH,Kinney JP,Denman DJ,Blanche TJ,Boyden ES

更新日期：2015-06-01 00:00:00

abstract：:Synaptic plasticity in the amygdala is thought to underlie aversive or rewarding learning and emotional memories. In this study, different mechanisms were found to underlie synaptic plasticity in lateral (LA) and basolateral (BLA) amygdala pathways to the primary output nucleus of the amygdala, the central amygdala (C...

journal_title：Journal of neurophysiology

authors： Fu Y,Shinnick-Gallagher P

更新日期：2005-05-01 00:00:00

abstract：:The activity of jaw muscle receptors was studied by recording neurons in the mesencephalic nucleus of the trigeminal nerve in monkeys trained to control the position and movement of their mandible. Jaw position was measured by a weighted lever resting on the mandibular incisors. The force required to maintain the posi...

journal_title：Journal of neurophysiology

authors： Larson CR,Finocchio DV,Smith A,Luschei ES

更新日期：1983-07-01 00:00:00

abstract：:Previous research using a loud acoustic stimulus (LAS) to investigate motor preparation in reaction time (RT) tasks indicates that responses can be triggered well in advance of the presentation of an imperative stimulus (IS). This is intriguing given that high levels of response preparation cannot be maintained for lo...

journal_title：Journal of neurophysiology

authors： Marinovic W,de Rugy A,Lipp OV,Tresilian JR

更新日期：2013-02-01 00:00:00

abstract：:1. We investigated gamma-aminobutyric acid (GABA) receptors using thin slice patch-clamp techniques in the swellings along axons of posterior pituitary nerve terminals. 2. Activation of the nerve terminal GABAA receptor induced a mean conductance change of 1.5 nS. Normalizing to area gave a mean conductance density of...

journal_title：Journal of neurophysiology

authors： Zhang SJ,Jackson MB

更新日期：1995-03-01 00:00:00

abstract：:The activity patterns in self- and cross-reinnervated flexor digitorum longus (FDL) and soleus (SOL) muscles were examined during natural movements in awake, unrestrained cats in which electromyographic (EMG) electrodes, tendon-force gauges, and muscle-length gauges had been chronically implanted under anesthesia and ...

journal_title：Journal of neurophysiology

authors： O'Donovan MJ,Pinter MJ,Dum RP,Burke RE

更新日期：1985-10-01 00:00:00

abstract：:1. We recorded single cell activities in the caudate nucleus of the monkeys trained to perform a series of visuomotor tasks. In the first part of this paper, we summarize the types and locations of neurons in the monkey caudate nucleus. In the second part, we report the characteristics of neurons related to saccadic e...

journal_title：Journal of neurophysiology

authors： Hikosaka O,Sakamoto M,Usui S

更新日期：1989-04-01 00:00:00

abstract：:1. To examine the effect of disruption of basal ganglia output on limb stability and movement, muscimol was injected into the internal globus pallidus (GPi) of monkeys trained to make arm movements to visible or remembered targets in a two-dimensional workspace. 2. Injections of as little as 0.25 micrograms muscimol a...

journal_title：Journal of neurophysiology

authors： Inase M,Buford JA,Anderson ME

更新日期：1996-03-01 00:00:00

abstract：:A seizure-paralysis repertoire characteristic of Drosophila "bang-sensitive" mutants can be evoked electroconvulsively in tethered flies, in which behavioral episodes are associated with synchronized spike discharges in different body parts. Flight muscle DLMs (dorsal longitudinal muscles) display a stereotypic sequen...

journal_title：Journal of neurophysiology

authors： Lee J,Wu CF

更新日期：2006-11-01 00:00:00

abstract：:We have used a computer-based mathematical model of alpha-motoneurons and of group Ia synaptic input to them, based on anatomical and electrophysiological data from the cat spinal cord, in order to examine the effects of variations in neuron size and input resistance and of conductance magnitude and duration on the ge...

journal_title：Journal of neurophysiology

authors： Lev-Tov A,Miller JP,Burke RE,Rall W

更新日期：1983-08-01 00:00:00

abstract：:Adult neuronal phenotype is maintained, at least in part, by the sensitivity of individual neurons to a specific selection of neurotrophic factors and the availability of such factors in the neurons' environment. Nerve growth factor (NGF) increases the functional expression of Na(+) channel currents (I(Na)) and both N...

journal_title：Journal of neurophysiology

authors： Ford CP,Wong KV,Lu VB,Posse de Chaves E,Smith PA

更新日期：2008-03-01 00:00:00

abstract：:The spinal network coordinating locomotion is comprised of a core of glutamate and glycine interneurons. This network is modulated by several transmitter systems including spinal GABA interneurons. The purpose of this study is to explore the contribution of GABAergic neurons to the regulation of locomotor burst freque...

journal_title：Journal of neurophysiology

authors： Schmitt DE,Hill RH,Grillner S

更新日期：2004-10-01 00:00:00