Abstract:
:DNA demethylating agents are approved for some blood malignancies and are under active investigation in solid tumors, but how these drugs work has remained unclear. In this issue of Cell, two groups show that these agents activate a toxic cellular antiviral program through transcriptional activation of endogenous retroviral sequences.
journal_name
Celljournal_title
Cellauthors
Licht JDdoi
10.1016/j.cell.2015.08.005subject
Has Abstractpub_date
2015-08-27 00:00:00pages
938-9issue
5eissn
0092-8674issn
1097-4172pii
S0092-8674(15)01018-1journal_volume
162pub_type
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