Ectopic gastric mucosa in proximal esophagus. Its clinical significance and hormonal profile.

Abstract:

:We have found 20 cases of ectopic gastric mucosa in the proximal esophagus. Five patients had symptoms, usually a burning sensation in the neck and/or dysphagia. We report the results of immunoperoxidase staining of this tissue for gastrin, somatostatin, vasoactive intestinal peptide, and bombesin. In 85% of biopsy specimens tested, one or more polypeptides were present. Gastrin and bombesin were found more frequently in symptomatic patients, and somatostatin in asymptomatic patients. Chronic inflammatory changes were more frequent in symptomatic patients.

journal_name

J Clin Gastroenterol

authors

Shah KK,DeRidder PH,Shah KK

doi

10.1097/00004836-198610000-00003

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

509-13

issue

5

eissn

0192-0790

issn

1539-2031

journal_volume

8

pub_type

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