Ulcer healing after treatment with sucralfate emulsion or ranitidine. Randomized controlled study in peptic ulcer disease.

abstract：:Among the factors involved in the pathogenesis of gastric ulcer, the reduced clearing capacity of the stomach seems to play an important role. On this basis, cisapride, which improves gastrointestinal motility, enhances gastric emptying, and prevents duodenogastric reflux, may be effective in the treatment of the gast...

journal_title：Journal of clinical gastroenterology

authors： Testoni PA,Bagnolo F,Buizza M,Masci E,Toti GL,Spinelli A,Manzi G

更新日期：1993-07-01 00:00:00

abstract：:Two patients with primary malignant lymphoma underwent spontaneous regression. One was a 40-year-old woman with a large ulcerating tumor on the greater curvature of the gastric antrum. This tumor shrank spontaneously, leaving only a small shallow ulcer. The resected specimen showed a minute focus of malignant lymphoma...

journal_title：Journal of clinical gastroenterology

authors： Shigematsu A,Iida M,Lien GS,Imamura T,Okada M,Fuchigami T,Fujishima M,Itoh H,Iwashita A

更新日期：1989-10-01 00:00:00

abstract：GOAL:Our aim was to investigate fecal microbiota transplantation (FMT) efficacy in patients with severe and/or complicated Clostridium difficile infection (CDI). BACKGROUND:FMT is successful for recurrent CDI, although its benefit in severe or complicated CDI has not specifically been evaluated. STUDY METHODS:A multi...

journal_title：Journal of clinical gastroenterology

authors： Aroniadis OC,Brandt LJ,Greenberg A,Borody T,Kelly CR,Mellow M,Surawicz C,Cagle L,Neshatian L,Stollman N,Giovanelli A,Ray A,Smith R

更新日期：2016-05-01 00:00:00

abstract：:A 53-year-old white woman developed diabetes mellitus, migratory erythema, and anemia, clinical features suggesting the presence of a "glucagonoma." Ten years earlier, after laparotomy and pancreatic biopsy, she had been told that she had an inoperable pancreatic carcinoma. Review of that biopsy together with current ...

journal_title：Journal of clinical gastroenterology

authors： Pitchumoni CS,Thelmo W,Ahmed KS,Kumar A,Davidian M,Einhorn R,Adler J,McCarthy J

更新日期：1979-09-01 00:00:00

abstract：GOALS:Our primary goal was to evaluate whether anti-tumor necrosis factor (TNF)-α trough levels above author-determined thresholds are associated with increased rates of mucosal healing among patients with Crohn's disease and ulcerative colitis. BACKGROUND:The introduction of anti-TNF agents has considerably advanced ...

journal_title：Journal of clinical gastroenterology

authors： Barnes EL,Allegretti JR

更新日期：2016-10-01 00:00:00

abstract：:Abnormalities in esophageal peristaltic function and acid clearance appear to be responsible for prolonged esophageal acid exposure, a major determinant of the reflux esophagitis and esophageal stricture. We evaluated esophageal motility by manometry in 50 healthy controls and in 35 symptomatic reflux patients before,...

journal_title：Journal of clinical gastroenterology

authors： Grande L,Lacima G,Ros E,Pujol A,Garcia-Valdecasas JC,Fuster J,Visa J,Pera C

更新日期：1991-02-01 00:00:00

abstract：:To avoid the two pitfalls of medicine, it is essential to maintain the distinction between "functional disorders" and "organic diseases." Medicalization consists in forgetting the suffering of a patient and focusing on a sick organ. This is incorrect scientifically, because it dismisses the complexity of science by de...

journal_title：Journal of clinical gastroenterology

authors： Devroede G

更新日期：1991-10-01 00:00:00

abstract：:A patient with long-standing Waldenström's disease and cryoglobulinemia, treated with chlorambucil, developed hepatocellular carcinoma. Although HBs antigen, anti-HBs, and anti-HBc antibodies were not detected in his serum by conventional polyclonal radioimmunoassays, immunofluorescence techniques showed HBs antigen t...

journal_title：Journal of clinical gastroenterology

authors： Lotz JP,Colbert N,Degott C,Pariente EA

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The efficacy of 6-mercaptopurine (6-MP) in the treatment and long-term maintenance of remission of inflammatory bowel disease and prevention of recurrence after resection in Crohn's disease have been established. Concern about 6-MP toxicity remains, especially the development of neoplasm. The aim of...

journal_title：Journal of clinical gastroenterology

authors： Warman JI,Korelitz BI,Fleisher MR,Janardhanam R

更新日期：2003-09-01 00:00:00

abstract：:The intestinal barrier serves 2 critical functions for the survival of the individual: first, it allows nutrient absorption and second, it defends the body from dangerous macromolecule penetration. It is a complex multilayer system, consisting of an external "anatomic" barrier and an inner "functional" immunological b...

journal_title：Journal of clinical gastroenterology

authors： Scaldaferri F,Pizzoferrato M,Gerardi V,Lopetuso L,Gasbarrini A

更新日期：2012-10-01 00:00:00

abstract：:Image-guided percutaneous local and regional modalities are major treatments for hepatocellular carcinoma. Patients having better liver function and performance are usually eligible and can gain significant survival benefit, especially with more limited tumor burden. The most common local therapies are ethanol and rad...

journal_title：Journal of clinical gastroenterology

authors： Pollak JS

更新日期：2013-07-01 00:00:00

abstract：:New-onset diabetes mellitus (DM) is one of the first symptoms of pancreatic adenocarcinoma (PDAC). The frequency of endocrine disorders is estimated between 40% and 80% in patients with pancreatic cancer. DM is a risk factor for cancer development but it may also be a consequence of the tumor growth. Data confirming t...

journal_title：Journal of clinical gastroenterology

authors： Wlodarczyk B,Gasiorowska A,Malecka-Panas E

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The Maastricht 2-2000 guidelines on the current management of Helicobacter pylori infection were recently adopted by the Israeli Gastroenterological Association. GOAL:To determine the impact of these clinical guidelines on the current knowledge, attitudes, and management of H. pylori among primary care phys...

journal_title：Journal of clinical gastroenterology

authors： Shirin H,Birkenfeld S,Shevah O,Levine A,Epstein J,Boaz M,Niv Y,Avni Y

更新日期：2004-04-01 00:00:00

abstract：:We suggest an approach to patients with gastric polyps, based on a study of 73 patients seen at this institution over a 5-year period. There were 40 cases of adenomatous and 20 cases of hamartomatous polyps. Differentiation between these two groups of polyps was not possible on the basis of clinical presentation, labo...

journal_title：Journal of clinical gastroenterology

authors： Fabry TL,Frankel A,Waye JD

更新日期：1982-02-01 00:00:00

abstract：AIM:To define whether human colonic mucosa exposure to Lactobacillus rhamnosus GG (LGG), American Type Culture Collection (ATCC) 53103, may influence intestinal muscle cell contractility. METHODS:Human colon specimens were obtained from disease-free margins of resected segments for cancer. The mucosa and submucosa, af...

journal_title：Journal of clinical gastroenterology

authors： Guarino MP,Altomare A,Stasi E,Marignani M,Severi C,Alloni R,Dicuonzo G,Morelli L,Coppola R,Cicala M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The current prevalence of primary antibiotic resistance of H. pylori is not known in Korea. This study was done to evaluate the prevalence of primary antibiotic resistance of H. pylori, and to evaluate the effect of point mutations of 23S rRNA on the rate of eradication of H. pylori. METHODS:H. pylori were ...

journal_title：Journal of clinical gastroenterology

authors： Hwang TJ,Kim N,Kim HB,Lee BH,Nam RH,Park JH,Lee MK,Park YS,Lee DH,Jung HC,Song IS

更新日期：2010-09-01 00:00:00

abstract：:Antacids have been used as remedies for benign gastroduodenal disorders for centuries. They were regarded to be effective in relieving gastric pain and symptoms of hyperacidity and in promoting ulcer healing. The effectiveness was based on empiric observations and was not derived from the controlled clinical trials da...

journal_title：Journal of clinical gastroenterology

authors： Sewing KF

更新日期：1991-01-01 00:00:00

abstract：:Ranitidine and cimetidine are competitive antagonists of histamine at H2-receptor sites in the gastric mucosa. Both drugs reduce output of basal and stimulated gastric acid and pepsin secretion in normal healthy subjects and duodenal ulcer patients. Pharmacodynamic and pharmacokinetic differences exist between the dru...

journal_title：Journal of clinical gastroenterology

authors： Richards DA

更新日期：1983-01-01 00:00:00

abstract：:We studied a young man with persistent elevation of transaminases and indirect bilirubin following acute viral hepatitis. Liver biopsy showed chronic persistent hepatitis, and clinical evaluation was otherwise negative for significant liver disease. The indirect-reacting serum bilirubin rose after both caloric restric...

journal_title：Journal of clinical gastroenterology

authors： Caldwell JH,Kirschner SD,Spagna VA,Inloes RL

更新日期：1981-03-01 00:00:00

abstract：:In our study, we evaluated whether the combination of two endoscopic abnormalities in the duodenum (the "mosaic" appearance and loss of duodenal folds) is significantly associated with duodenal villous atrophy secondary to celiac sprue in adults. Fourteen patients referred for esophagogastroduodenoscopy for suspected ...

journal_title：Journal of clinical gastroenterology

authors： Magazzu G,Bottari M,Tuccari G,Arco A,Pallio S,Lucanto C,Tortora A,Barresi G

更新日期：1994-10-01 00:00:00

abstract：:A 65-year-old Japanese woman had primary biliary cirrhosis (PBC) and chronic pancreatitis associated with ulcerative colitis. The association of PBC and ulcerative colitis may prove to be valid. ...

journal_title：Journal of clinical gastroenterology

authors： Kato Y,Morimoto H,Unoura M,Kobayashi K,Hattori N,Nakanuma Y

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Guidelines recommend upper endoscopic screening of cirrhotic patients for gastroesophageal varices. Cirrhosis is not always distinguishable from chronic hepatitis. GOALS:To identify low-risk patients who can be spared upper endoscopy irrespective of a diagnosis of cirrhosis. STUDY:We evaluated 13 nonendosc...

journal_title：Journal of clinical gastroenterology

authors： Gentile I,Viola C,Graf M,Liuzzi R,Quarto M,Cerini R,Piazza M,Borgia G

更新日期：2009-01-01 00:00:00

abstract：:We reviewed 15 cases of poisoning from ingestion of yellow phosphorus-containing fireworks and analyzed its associated acute hepatotoxic effects. Two patients (13%) had no clinical or biochemical evidence of hepatic damage, four (27%) had subclinical hepatic injury, five (33%) manifested varying degrees of hepatocellu...

journal_title：Journal of clinical gastroenterology

authors： Fernandez OU,Canizares LL

更新日期：1995-09-01 00:00:00

abstract：GOALS:The goal of this study was to elucidate the most important predictors for elevation of gastrin in patients on long-term PPI therapy through analysis of data from 2 published studies in Icelandic patients with erosive GERD. BACKGROUND:Gastrin elevation is a known but variable consequence of proton pump inhibitor ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Lund SH,Gizurarson S,Metz DC,Björnsson ES

更新日期：2020-03-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in adults and children and is currently the third most common indication for liver transplantation in North America. Its pathogenesis is thought to be secondary to multiple "hits" derived from the dietary components, adipose tissue, imm...

journal_title：Journal of clinical gastroenterology

authors： Mouzaki M,Allard JP

更新日期：2012-07-01 00:00:00

abstract：GOALS:To estimate the hepatocellular carcinoma surveillance in the Medicaid cirrhotic population. BACKGROUND:Most studies predate 2005 American Association for the Study of Liver Diseases surveillance recommendations and do not examine the primary target population, cirrhotics. STUDY:From 2006 to 2007, we identified ...

journal_title：Journal of clinical gastroenterology

authors： Palmer LB,Kappelman MD,Sandler RS,Hayashi PH

更新日期：2013-09-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) commonly affects women of childbearing age, leading to concerns about the effects of the disease on fertility and pregnancy, the effect of pregnancy on the disease, and the diagnosis and treatment of IBD in the pregnancy women. The literature regarding these issues is reviewed, and a r...

journal_title：Journal of clinical gastroenterology

authors： Vender RJ,Spiro HM

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Clostridium difficile is a bacterial pathogen associated with significant morbidity and mortality in patients with cirrhosis. GOALS:Our primary aim is to identify variables that are predictive of poor outcomes in cirrhosis patients with C. difficile infection (CDI). We also aim to further characterize the r...

journal_title：Journal of clinical gastroenterology

authors： Smith EZ,Northup PG,Argo CK

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Although sessile serrated adenomas (SSAs) may represent a separate and important pathway for colorectal cancer (CRC), little is known about the risk factors for these lesions. Molecular abnormalities such as BRAF have been observed in SSA and smokers. Our hypothesis is that smoking may be associated with the...

journal_title：Journal of clinical gastroenterology

authors： Anderson JC,Rangasamy P,Rustagi T,Myers M,Sanders M,Vaziri H,Wu G,Birk JW,Protiva P

更新日期：2011-09-01 00:00:00

abstract：:Infliximab is efficacious for refractory Crohn's disease, but delayed hypersensitivity reactions preclude retreatment for patients experiencing this complication. We report the results of four patients offered enrollment in an open label trial of thalidomide as "salvage" therapy for their refractory disease. Two patie...

journal_title：Journal of clinical gastroenterology

authors： Kane S,Stone LJ,Ehrenpreis E

更新日期：2002-08-01 00:00:00