Abstract：
:Advances in retooling microorganisms have enabled bioproduction of 'drop-in' biofuels, fuels that are compatible with existing spark-ignition, compression-ignition, and gas-turbine engines. As the majority of petroleum consumption in the United States consists of gasoline (47%), diesel fuel and heating oil (21%), and jet fuel (8%), 'drop-in' biofuels that replace these petrochemical sources are particularly attractive. In this review, we discuss the application of aldehyde decarbonylases to produce gasoline substitutes from fatty acid products, a recently crystallized reductase that could hydrogenate jet fuel precursors from terpene synthases, and the exquisite control of polyketide synthases to produce biofuels with desired physical properties (e.g., lower freezing points). With our increased understanding of biosynthetic logic of metabolic pathways, we discuss the unique advantages of fatty acid, terpene, and polyketide synthases for the production of bio-based gasoline, diesel and jet fuel.
journal_name
Curr Opin Biotechnoljournal_title
Current opinion in biotechnologyauthors
Zargar A,Bailey CB,Haushalter RW,Eiben CB,Katz L,Keasling JDdoi
10.1016/j.copbio.2017.03.004subject
Has Abstractpub_date
2017-06-01 00:00:00pages
156-163eissn
0958-1669issn
1879-0429pii
S0958-1669(16)30190-2journal_volume
45pub_type
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journal_title：Current opinion in biotechnology
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journal_title：Current opinion in biotechnology
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journal_title：Current opinion in biotechnology
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