Abstract:
:AMPA receptor (AMPAR) complexes comprise four of the AMPAR subunits GluA1-4 and several additional interacting proteins. Subunit composition determines AMPAR function. However, AMPAR function depends to a large extent also on interacting proteins, which influence trafficking to the cell surface, activity-dependent subcellular localization and gating of AMPARs. In this review we report about recent findings on the diversity of AMPAR complexes that allow us to better understand functional properties of native receptors in the brain.
journal_name
Curr Opin Neurobioljournal_title
Current opinion in neurobiologyauthors
Jacobi E,von Engelhardt Jdoi
10.1016/j.conb.2017.03.001subject
Has Abstractpub_date
2017-08-01 00:00:00pages
32-38eissn
0959-4388issn
1873-6882pii
S0959-4388(16)30184-2journal_volume
45pub_type
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