Adult NSC diversity and plasticity: the role of the niche.

abstract：:Not only is the sense of smell of pivotal importance to most animals but also serves as a significant model system in biological research. In recent years, great strides in our understanding of how the olfactory system is organized and operates have been made. Instrumental in these efforts has been work performed in D...

journal_title：Current opinion in neurobiology

authors： Mansourian S,Stensmyr MC

更新日期：2015-10-01 00:00:00

abstract：:Acetylcholine is the specific chemical code of spinal nerve terminal transmission at the mammalian neuromuscular junction (NMJ), whereas nicotinic acetylcholine receptors inserted into the membrane of muscle fibres mediate signalling for the muscle response. Glutamate has a primary role in neuromuscular transmission o...

journal_title：Current opinion in neurobiology

authors： Pizzi M,Brunelli G,Barlati S,Spano P

更新日期：2006-06-01 00:00:00

abstract：:The cadherin superfamily is a large (now more than 100 proteins) protein family originally identified as cell adhesion molecules. Each cadherin shows distinct expression patterns in the nervous system, and their expressions are both spatially and temporally regulated and diverse among different species. Mounting evide...

journal_title：Current opinion in neurobiology

authors： Matsunaga E,Okanoya K

更新日期：2014-10-01 00:00:00

abstract：:Slow waves, the hallmark of NREM (Non Rapid Eye Movement) sleep, are not uniformly distributed across the cortical surface, but can occur locally and asynchronously across brain regions. Their regional distribution and amplitude is affected by brain maturation and by time spent awake, mediated in part by experience-de...

journal_title：Current opinion in neurobiology

authors： Siclari F,Tononi G

更新日期：2017-06-01 00:00:00

abstract：:Genetically encoded sensors of neural activity enable visualization of circuit-level function in the central nervous system. Although our understanding of the molecular events that regulate neuronal firing, synaptic function, and plasticity has expanded rapidly over the past 15 years, an appreciation for how cellular ...

journal_title：Current opinion in neurobiology

authors： Barth AL

更新日期：2007-10-01 00:00:00

abstract：:The primary reactions of the chemo-electrical signal transduction pathway in olfactory receptor neurons are mediated by two alternative second messengers, cAMP and inositol 1,4,5-trisphosphate. The rapid and transient intracellular signalling is terminated by the action of negative-feedback loops which uncouple the re...

journal_title：Current opinion in neurobiology

authors： Breer H,Boekhoff I

更新日期：1992-08-01 00:00:00

abstract：:Ionotropic AMPA-type glutamate receptors and G-protein-coupled metabotropic GABAB receptors are key elements of neurotransmission whose cellular functions are determined by their protein constituents. Over the past couple of years unbiased proteomic approaches identified comprehensive sets of protein building blocks o...

journal_title：Current opinion in neurobiology

authors： Bettler B,Fakler B

更新日期：2017-08-01 00:00:00

abstract：:The fruit fly, Drosophila melanogaster, is equipped with a sophisticated olfactory sensory system that permits it to recognize and discriminate hundreds of discrete odorants. The perception of these odorants is essential for the animal to identify relevant food sources and suitable sites for egg-laying. Advances in th...

journal_title：Current opinion in neurobiology

authors： Vosshall LB

更新日期：2000-08-01 00:00:00

abstract：:Accepting, rejecting or modifying the many different theories of the cerebellum's role in the control of movement requires an understanding of the signals encoded in the discharge of cerebellar neurons and how those signals are transformed by the cerebellar circuitry. Particularly challenging is understanding the sens...

journal_title：Current opinion in neurobiology

authors： Ebner TJ

更新日期：1998-12-01 00:00:00

abstract：:Recent behavioral studies of infants have provided further evidence for the existence of cognitive and perceptual abilities in the first few months of life. Additional evidence from developmental neuroscience and comparative psychology has supported the view that, in some domains, such as visual attention and face and...

journal_title：Current opinion in neurobiology

authors： Johnson MH

更新日期：1994-04-01 00:00:00

abstract：:Recent findings suggest that cerebral laterality will not be understood in terms of simple dichotomies, such as the idea that the left hemisphere is analytic and the right holistic. Rather, hemisphere differences can be better explained in terms of relatively specific principles that extend over limited domains. For v...

journal_title：Current opinion in neurobiology

authors： Brown HD,Kosslyn SM

更新日期：1993-04-01 00:00:00

abstract：:Thermal information about skin surface temperature is a key sense for the perception of object identity and valence. The identification of ion channels involved in the transduction of thermal changes has provided a genetic access point to the thermal system. However, from sensory specific 'labeled-lines' to multimodal...

journal_title：Current opinion in neurobiology

authors： Bokiniec P,Zampieri N,Lewin GR,Poulet JF

更新日期：2018-10-01 00:00:00

abstract：:Dendritic patterning exerts a profound influence on neuronal connectivity. Recent studies indicate that mammalian Notch receptors are expressed by postmitotic neurons and that Notch signaling has a considerable influence on dendritic growth and branching. Investigations into the intracellular effectors of dendritic de...

journal_title：Current opinion in neurobiology

authors： Redmond L,Ghosh A

更新日期：2001-02-01 00:00:00

abstract：:The precise causal factors for obsessive-compulsive disorder (OCD) are not known, although, decades of research have honed in on the cortico-striatal-thalamo-cortical (CSTC) circuitry in the brain as a critical pathway involved in obsessions and the intimately linked compulsive-repetitive behaviors. Recent progress in...

journal_title：Current opinion in neurobiology

authors： Ting JT,Feng G

更新日期：2011-12-01 00:00:00

abstract：:Slow axonal transport conveys cytosolic and cytoskeletal proteins into axons and synapses at overall velocities that are several orders of magnitude slower than the fast transport of membranous organelles such as vesicles and mitochondria. The phenomenon of slow transport was characterized by in vivo pulse-chase radio...

journal_title：Current opinion in neurobiology

authors： Roy S

更新日期：2020-08-01 00:00:00

abstract：:The view of cerebellar functions has been extended from controlling sensorimotor processes to processing 'contextual' information and generating predictions for a diverse range of behaviors. These functions rely on the computation of the local cerebellar microcircuits and long-range connectivity that relays cerebellar...

journal_title：Current opinion in neurobiology

authors： Xiao L,Scheiffele P

更新日期：2018-02-01 00:00:00

abstract：:Optical imaging methods are powerful tools in neuroscience as they can systematically monitor the activity of neuronal populations with high spatiotemporal resolution using calcium or voltage indicators. Moreover, caged compounds and optogenetic actuators enable to optically manipulate neural activity. Among optical m...

journal_title：Current opinion in neurobiology

authors： Yang W,Yuste R

更新日期：2018-06-01 00:00:00

abstract：:This past year has seen significant advances in our understanding of the physiology of emotion. Attention continues to focus on the amygdala and its interconnections with prefrontal cortical regions. New evidence underscores the importance of lateralization for emotion. There are also new findings on the physiological...

journal_title：Current opinion in neurobiology

authors： Davidson RJ,Sutton SK

更新日期：1995-04-01 00:00:00

abstract：:The recent cloning of the gamma-aminobutyric acid and norepinephrine Na(+)-dependent neurotransmitter transporters has led to new approaches for understanding the structure and function of these important synaptic proteins and provides a conceptual model in which to consider recent advances in the physiology, pharmaco...

journal_title：Current opinion in neurobiology

authors： Amara SG,Pacholczyk T

更新日期：1991-06-01 00:00:00

abstract：:Cerebellar long-term depression is a persistent, input-specific attenuation of the parallel fiber-Purkinje neuron synapse induced by co-activation of parallel fibers and climbing fibers. This phenomenon endows the Purkinje neuron with a powerful associative computational ability. Recent investigations have provided st...

journal_title：Current opinion in neurobiology

authors： Linden DJ,Connor JA

更新日期：1993-06-01 00:00:00

abstract：:Several advances have been made recently in characterizing neural progenitor cells. In vertebrates, multipotential stem cells have been demonstrated in the developing forebrain both in vitro and in vivo, and a class of stem cells has been identified in the adult CNS. Factors that regulate the proliferation and differe...

journal_title：Current opinion in neurobiology

authors： Temple S,Qian X

更新日期：1996-02-01 00:00:00

abstract：:Genetic mosaic techniques provide a powerful tool for dissecting gene function in the intricate genetic networks that underlie the formation and function of nervous systems. For instance, it is possible to make individual cells or groups of cells homozygous for mutations of interest at specific points during an organi...

journal_title：Current opinion in neurobiology

authors： Zugates CT,Lee T

更新日期：2004-10-01 00:00:00

abstract：:Most high-level sensory neurons have complex, nonlinear response properties; a comprehensive characterization of these properties remains a formidable challenge. Recent studies using complex sensory stimuli combined with linear and nonlinear analyses have provided new insights into the neuronal response properties in ...

journal_title：Current opinion in neurobiology

authors： Touryan J,Dan Y

更新日期：2001-08-01 00:00:00

abstract：:In order to understand how brain activity produces adaptive behavior we need large-scale, high-resolution recordings of neuronal activity. Fluorescent genetically encoded voltage indicators (GEVIs) offer the potential for these recordings to be performed chronically from targeted cells in a minimally invasive manner. ...

journal_title：Current opinion in neurobiology

authors： Platisa J,Pieribone VA

更新日期：2018-06-01 00:00:00

abstract：:Precise formation of neuronal circuits requires the coordinated development of the different components of the circuit. Here, we review examples of coordination at multiples scales of development in one of the best-studied systems for neural patterning and circuit assembly, the Drosophila visual system, from coordinat...

journal_title：Current opinion in neurobiology

authors： Courgeon M,Desplan C

更新日期：2019-06-01 00:00:00

abstract：:Classical eyelid conditioning has been used to great advantage in demonstrating that the cerebellum helps to improve movements through experience, and in identifying the underlying mechanisms. Results from recent studies support the hypotheses that learning occurs in both the cerebellar nucleus and cortex, and that th...

journal_title：Current opinion in neurobiology

authors： Medina JF,Nores WL,Ohyama T,Mauk MD

更新日期：2000-12-01 00:00:00

abstract：:Priming is a nonconscious form of memory in which an encounter with a stimulus influences the subsequent identification, production or classification of the same or a related stimulus. Neuroimaging studies have revealed that behavioral priming is typically accompanied by reduced activity in several cortical regions. W...

journal_title：Current opinion in neurobiology

authors： Schacter DL,Wig GS,Stevens WD

更新日期：2007-04-01 00:00:00

abstract：:The decision to urinate is a social behavior that is calculated multiple times a day. Many animals perform urine scent-marking which broadcasts their pheromones to regulate the behavior of others and humans are trained at an early age to urinate only at a socially acceptable time and place. The inability to control wh...

journal_title：Current opinion in neurobiology

authors： Mukhopadhyay S,Stowers L

更新日期：2020-02-01 00:00:00

abstract：:Recent studies show that anatomical and functional brain networks exhibit similar small-world properties. However, the networks that are compared often differ in what the nodes represent (e.g. sensors or brain areas), what kind of connectivity is measured, and what temporal and spatial scales are probed. Here, I revie...

journal_title：Current opinion in neurobiology

authors： Ioannides AA

更新日期：2007-04-01 00:00:00

abstract：:At least one non-human primate species-the marmoset monkey-exhibits developmental processes similar to human vocal development. These processes include babbling-like early vocal output and a role for social feedback in changing this output into mature-sounding vocalizations. Such parallel behaviors provide a window th...

journal_title：Current opinion in neurobiology

authors： Ghazanfar AA,Zhang YS

更新日期：2016-10-01 00:00:00